LeishMANIAdb
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Secreted protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Secreted protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania major
UniProt:
Q4Q6H2_LEIMA
TriTrypDb:
LmjF.31.0910 , LMJLV39_310015000 * , LMJSD75_310014700 *
Length:
168

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 3
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q6H2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q6H2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 4 6 PF00675 0.584
CLV_PCSK_KEX2_1 4 6 PF00082 0.584
CLV_PCSK_KEX2_1 66 68 PF00082 0.561
CLV_PCSK_PC1ET2_1 66 68 PF00082 0.561
CLV_PCSK_SKI1_1 149 153 PF00082 0.645
CLV_PCSK_SKI1_1 4 8 PF00082 0.702
CLV_PCSK_SKI1_1 90 94 PF00082 0.481
CLV_PCSK_SKI1_1 97 101 PF00082 0.421
DEG_APCC_KENBOX_2 22 26 PF00400 0.483
DEG_Nend_Nbox_1 1 3 PF02207 0.520
DOC_CKS1_1 91 96 PF01111 0.472
DOC_CYCLIN_RxL_1 102 112 PF00134 0.502
DOC_USP7_MATH_1 15 19 PF00917 0.482
DOC_USP7_MATH_1 39 43 PF00917 0.570
DOC_WW_Pin1_4 83 88 PF00397 0.496
DOC_WW_Pin1_4 90 95 PF00397 0.457
LIG_14-3-3_CanoR_1 67 74 PF00244 0.579
LIG_APCC_ABBA_1 19 24 PF00400 0.474
LIG_CSL_BTD_1 28 31 PF09270 0.504
LIG_FHA_1 98 104 PF00498 0.540
LIG_SH2_STAT5 130 133 PF00017 0.671
LIG_SH3_3 81 87 PF00018 0.631
MOD_CDK_SPxxK_3 83 90 PF00069 0.495
MOD_CK2_1 114 120 PF00069 0.510
MOD_CK2_1 39 45 PF00069 0.479
MOD_CK2_1 83 89 PF00069 0.549
MOD_GlcNHglycan 100 103 PF01048 0.429
MOD_GlcNHglycan 71 74 PF01048 0.699
MOD_GSK3_1 109 116 PF00069 0.524
MOD_NEK2_1 107 112 PF00069 0.470
MOD_NEK2_1 132 137 PF00069 0.669
MOD_NEK2_1 68 73 PF00069 0.583
MOD_NEK2_1 98 103 PF00069 0.479
MOD_PKA_2 68 74 PF00069 0.554
MOD_PKB_1 67 75 PF00069 0.580
MOD_Plk_4 15 21 PF00069 0.478
MOD_ProDKin_1 83 89 PF00069 0.496
MOD_ProDKin_1 90 96 PF00069 0.453
MOD_SUMO_for_1 54 57 PF00179 0.494
TRG_DiLeu_BaLyEn_6 2 7 PF01217 0.509
TRG_ER_diArg_1 4 6 PF00400 0.566
TRG_Pf-PMV_PEXEL_1 4 9 PF00026 0.494

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8IIG0 Leishmania donovani 72% 100%
A4I6L7 Leishmania infantum 72% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS