Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q6G1_LEIMA

TriTrypDb:

LmjF.31.1020 , LMJLV39_310016300 , LMJSD75_310015900

Length:

951

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q6G1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q6G1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	121	125	PF00656	0.658
CLV_C14_Caspase3-7	16	20	PF00656	0.690
CLV_C14_Caspase3-7	236	240	PF00656	0.643
CLV_C14_Caspase3-7	34	38	PF00656	0.594
CLV_C14_Caspase3-7	864	868	PF00656	0.630
CLV_C14_Caspase3-7	915	919	PF00656	0.661
CLV_NRD_NRD_1	144	146	PF00675	0.693
CLV_NRD_NRD_1	222	224	PF00675	0.568
CLV_NRD_NRD_1	275	277	PF00675	0.679
CLV_NRD_NRD_1	284	286	PF00675	0.361
CLV_NRD_NRD_1	290	292	PF00675	0.493
CLV_NRD_NRD_1	329	331	PF00675	0.655
CLV_NRD_NRD_1	472	474	PF00675	0.561
CLV_NRD_NRD_1	505	507	PF00675	0.426
CLV_NRD_NRD_1	52	54	PF00675	0.658
CLV_NRD_NRD_1	528	530	PF00675	0.443
CLV_NRD_NRD_1	580	582	PF00675	0.458
CLV_NRD_NRD_1	721	723	PF00675	0.433
CLV_NRD_NRD_1	787	789	PF00675	0.494
CLV_PCSK_KEX2_1	144	146	PF00082	0.679
CLV_PCSK_KEX2_1	222	224	PF00082	0.568
CLV_PCSK_KEX2_1	275	277	PF00082	0.753
CLV_PCSK_KEX2_1	286	288	PF00082	0.489
CLV_PCSK_KEX2_1	290	292	PF00082	0.505
CLV_PCSK_KEX2_1	299	301	PF00082	0.480
CLV_PCSK_KEX2_1	329	331	PF00082	0.655
CLV_PCSK_KEX2_1	472	474	PF00082	0.532
CLV_PCSK_KEX2_1	505	507	PF00082	0.426
CLV_PCSK_KEX2_1	52	54	PF00082	0.692
CLV_PCSK_KEX2_1	528	530	PF00082	0.443
CLV_PCSK_KEX2_1	580	582	PF00082	0.507
CLV_PCSK_KEX2_1	721	723	PF00082	0.460
CLV_PCSK_KEX2_1	78	80	PF00082	0.558
CLV_PCSK_KEX2_1	787	789	PF00082	0.494
CLV_PCSK_PC1ET2_1	286	288	PF00082	0.482
CLV_PCSK_PC1ET2_1	299	301	PF00082	0.497
CLV_PCSK_PC1ET2_1	78	80	PF00082	0.558
CLV_PCSK_PC7_1	524	530	PF00082	0.444
CLV_PCSK_SKI1_1	395	399	PF00082	0.697
CLV_PCSK_SKI1_1	499	503	PF00082	0.515
CLV_PCSK_SKI1_1	556	560	PF00082	0.485
CLV_PCSK_SKI1_1	619	623	PF00082	0.401
CLV_PCSK_SKI1_1	721	725	PF00082	0.492
CLV_PCSK_SKI1_1	788	792	PF00082	0.486
CLV_PCSK_SKI1_1	845	849	PF00082	0.568
DEG_MDM2_SWIB_1	614	621	PF02201	0.434
DEG_SPOP_SBC_1	653	657	PF00917	0.509
DEG_SPOP_SBC_1	730	734	PF00917	0.677
DOC_CDC14_PxL_1	536	544	PF14671	0.387
DOC_CDC14_PxL_1	639	647	PF14671	0.599
DOC_CYCLIN_RxL_1	552	563	PF00134	0.462
DOC_CYCLIN_RxL_1	613	624	PF00134	0.394
DOC_CYCLIN_yCln2_LP_2	723	726	PF00134	0.458
DOC_MAPK_gen_1	66	75	PF00069	0.643
DOC_MAPK_gen_1	78	84	PF00069	0.503
DOC_PP1_RVXF_1	497	503	PF00149	0.532
DOC_PP2B_LxvP_1	47	50	PF13499	0.557
DOC_PP2B_LxvP_1	723	726	PF13499	0.458
DOC_PP4_FxxP_1	210	213	PF00568	0.539
DOC_USP7_MATH_1	183	187	PF00917	0.640
DOC_USP7_MATH_1	226	230	PF00917	0.518
DOC_USP7_MATH_1	248	252	PF00917	0.669
DOC_USP7_MATH_1	258	262	PF00917	0.696
DOC_USP7_MATH_1	263	267	PF00917	0.706
DOC_USP7_MATH_1	345	349	PF00917	0.569
DOC_USP7_MATH_1	354	358	PF00917	0.637
DOC_USP7_MATH_1	364	368	PF00917	0.571
DOC_USP7_MATH_1	465	469	PF00917	0.672
DOC_USP7_MATH_1	490	494	PF00917	0.417
DOC_USP7_MATH_1	592	596	PF00917	0.457
DOC_USP7_MATH_1	652	656	PF00917	0.621
DOC_USP7_MATH_1	728	732	PF00917	0.612
DOC_USP7_MATH_1	794	798	PF00917	0.483
DOC_USP7_MATH_1	847	851	PF00917	0.653
DOC_USP7_UBL2_3	295	299	PF12436	0.538
DOC_USP7_UBL2_3	62	66	PF12436	0.657
DOC_WW_Pin1_4	157	162	PF00397	0.713
DOC_WW_Pin1_4	231	236	PF00397	0.641
DOC_WW_Pin1_4	726	731	PF00397	0.585
DOC_WW_Pin1_4	835	840	PF00397	0.552
LIG_14-3-3_CanoR_1	144	149	PF00244	0.647
LIG_14-3-3_CanoR_1	225	235	PF00244	0.557
LIG_14-3-3_CanoR_1	567	577	PF00244	0.429
LIG_14-3-3_CanoR_1	580	588	PF00244	0.574
LIG_14-3-3_CanoR_1	69	74	PF00244	0.615
LIG_14-3-3_CanoR_1	79	85	PF00244	0.535
LIG_14-3-3_CanoR_1	819	826	PF00244	0.556
LIG_Actin_WH2_2	353	371	PF00022	0.668
LIG_BRCT_BRCA1_1	874	878	PF00533	0.539
LIG_BRCT_BRCA1_2	874	880	PF00533	0.538
LIG_Clathr_ClatBox_1	645	649	PF01394	0.478
LIG_CSL_BTD_1	232	235	PF09270	0.603
LIG_deltaCOP1_diTrp_1	615	622	PF00928	0.389
LIG_deltaCOP1_diTrp_1	693	698	PF00928	0.374
LIG_eIF4E_1	496	502	PF01652	0.533
LIG_EVH1_1	724	728	PF00568	0.577
LIG_FHA_1	103	109	PF00498	0.698
LIG_FHA_1	242	248	PF00498	0.702
LIG_FHA_1	350	356	PF00498	0.638
LIG_FHA_1	370	376	PF00498	0.721
LIG_FHA_1	456	462	PF00498	0.617
LIG_FHA_1	934	940	PF00498	0.614
LIG_FHA_2	133	139	PF00498	0.695
LIG_FHA_2	234	240	PF00498	0.639
LIG_FHA_2	545	551	PF00498	0.508
LIG_FHA_2	818	824	PF00498	0.685
LIG_FHA_2	920	926	PF00498	0.720
LIG_GSK3_LRP6_1	726	732	PF00069	0.570
LIG_LIR_Apic_2	208	213	PF02991	0.541
LIG_LIR_Apic_2	376	380	PF02991	0.581
LIG_LIR_Gen_1	306	315	PF02991	0.462
LIG_LIR_Gen_1	611	622	PF02991	0.439
LIG_LIR_Gen_1	636	646	PF02991	0.662
LIG_LIR_Gen_1	64	75	PF02991	0.762
LIG_LIR_Gen_1	83	92	PF02991	0.503
LIG_LIR_Gen_1	945	951	PF02991	0.546
LIG_LIR_Nem_3	306	311	PF02991	0.460
LIG_LIR_Nem_3	442	448	PF02991	0.502
LIG_LIR_Nem_3	611	617	PF02991	0.416
LIG_LIR_Nem_3	620	625	PF02991	0.370
LIG_LIR_Nem_3	636	642	PF02991	0.466
LIG_LIR_Nem_3	64	70	PF02991	0.797
LIG_LIR_Nem_3	763	769	PF02991	0.727
LIG_LIR_Nem_3	83	88	PF02991	0.481
LIG_LIR_Nem_3	945	950	PF02991	0.565
LIG_MYND_1	209	213	PF01753	0.539
LIG_Pex14_1	618	622	PF04695	0.390
LIG_Pex14_1	695	699	PF04695	0.356
LIG_Pex14_2	614	618	PF04695	0.381
LIG_Pex14_2	942	946	PF04695	0.573
LIG_SH2_CRK	390	394	PF00017	0.658
LIG_SH2_CRK	445	449	PF00017	0.656
LIG_SH2_NCK_1	377	381	PF00017	0.575
LIG_SH2_PTP2	537	540	PF00017	0.376
LIG_SH2_SRC	537	540	PF00017	0.463
LIG_SH2_SRC	95	98	PF00017	0.654
LIG_SH2_STAP1	146	150	PF00017	0.649
LIG_SH2_STAP1	496	500	PF00017	0.377
LIG_SH2_STAT5	106	109	PF00017	0.648
LIG_SH2_STAT5	537	540	PF00017	0.376
LIG_SH2_STAT5	628	631	PF00017	0.498
LIG_SH2_STAT5	702	705	PF00017	0.419
LIG_SH2_STAT5	766	769	PF00017	0.564
LIG_SH3_1	722	728	PF00018	0.423
LIG_SH3_3	107	113	PF00018	0.696
LIG_SH3_3	240	246	PF00018	0.743
LIG_SH3_3	70	76	PF00018	0.654
LIG_SH3_3	722	728	PF00018	0.503
LIG_SH3_3	753	759	PF00018	0.608
LIG_SH3_3	91	97	PF00018	0.576
LIG_SH3_4	893	900	PF00018	0.619
LIG_SUMO_SIM_anti_2	438	445	PF11976	0.563
LIG_SUMO_SIM_par_1	105	112	PF11976	0.699
LIG_SUMO_SIM_par_1	644	650	PF11976	0.480
LIG_SUMO_SIM_par_1	80	86	PF11976	0.454
LIG_SUMO_SIM_par_1	802	809	PF11976	0.517
LIG_TRAF2_1	279	282	PF00917	0.483
LIG_TRAF2_1	321	324	PF00917	0.595
LIG_TRAF2_1	712	715	PF00917	0.607
LIG_TYR_ITIM	443	448	PF00017	0.655
LIG_TYR_ITIM	533	538	PF00017	0.465
LIG_WRC_WIRS_1	795	800	PF05994	0.434
MOD_CDK_SPxxK_3	157	164	PF00069	0.669
MOD_CK1_1	266	272	PF00069	0.664
MOD_CK1_1	30	36	PF00069	0.688
MOD_CK1_1	341	347	PF00069	0.589
MOD_CK1_1	358	364	PF00069	0.684
MOD_CK1_1	416	422	PF00069	0.653
MOD_CK1_1	453	459	PF00069	0.528
MOD_CK1_1	468	474	PF00069	0.472
MOD_CK1_1	5	11	PF00069	0.702
MOD_CK1_1	584	590	PF00069	0.587
MOD_CK1_1	655	661	PF00069	0.616
MOD_CK1_1	729	735	PF00069	0.628
MOD_CK1_1	828	834	PF00069	0.741
MOD_CK1_1	83	89	PF00069	0.564
MOD_CK1_1	919	925	PF00069	0.688
MOD_CK1_1	945	951	PF00069	0.632
MOD_CK2_1	132	138	PF00069	0.662
MOD_CK2_1	148	154	PF00069	0.534
MOD_CK2_1	184	190	PF00069	0.610
MOD_CK2_1	276	282	PF00069	0.566
MOD_CK2_1	318	324	PF00069	0.629
MOD_CK2_1	364	370	PF00069	0.661
MOD_CK2_1	544	550	PF00069	0.474
MOD_CK2_1	641	647	PF00069	0.567
MOD_CK2_1	709	715	PF00069	0.470
MOD_CK2_1	817	823	PF00069	0.711
MOD_CMANNOS	695	698	PF00535	0.360
MOD_DYRK1A_RPxSP_1	157	161	PF00069	0.644
MOD_GlcNHglycan	251	254	PF01048	0.634
MOD_GlcNHglycan	260	263	PF01048	0.757
MOD_GlcNHglycan	268	271	PF01048	0.629
MOD_GlcNHglycan	29	32	PF01048	0.734
MOD_GlcNHglycan	313	316	PF01048	0.542
MOD_GlcNHglycan	347	350	PF01048	0.580
MOD_GlcNHglycan	453	456	PF01048	0.606
MOD_GlcNHglycan	46	50	PF01048	0.788
MOD_GlcNHglycan	562	565	PF01048	0.413
MOD_GlcNHglycan	588	591	PF01048	0.618
MOD_GlcNHglycan	659	662	PF01048	0.605
MOD_GlcNHglycan	7	10	PF01048	0.667
MOD_GlcNHglycan	711	714	PF01048	0.500
MOD_GlcNHglycan	808	811	PF01048	0.607
MOD_GlcNHglycan	867	870	PF01048	0.657
MOD_GlcNHglycan	899	902	PF01048	0.588
MOD_GlcNHglycan	904	907	PF01048	0.568
MOD_GSK3_1	144	151	PF00069	0.668
MOD_GSK3_1	227	234	PF00069	0.594
MOD_GSK3_1	249	256	PF00069	0.678
MOD_GSK3_1	258	265	PF00069	0.681
MOD_GSK3_1	266	273	PF00069	0.580
MOD_GSK3_1	324	331	PF00069	0.612
MOD_GSK3_1	341	348	PF00069	0.643
MOD_GSK3_1	350	357	PF00069	0.620
MOD_GSK3_1	369	376	PF00069	0.681
MOD_GSK3_1	415	422	PF00069	0.634
MOD_GSK3_1	451	458	PF00069	0.624
MOD_GSK3_1	579	586	PF00069	0.575
MOD_GSK3_1	637	644	PF00069	0.549
MOD_GSK3_1	65	72	PF00069	0.669
MOD_GSK3_1	652	659	PF00069	0.637
MOD_GSK3_1	668	675	PF00069	0.380
MOD_GSK3_1	726	733	PF00069	0.630
MOD_GSK3_1	815	822	PF00069	0.663
MOD_GSK3_1	827	834	PF00069	0.596
MOD_GSK3_1	865	872	PF00069	0.624
MOD_N-GLC_1	183	188	PF02516	0.662
MOD_N-GLC_1	239	244	PF02516	0.618
MOD_N-GLC_1	27	32	PF02516	0.710
MOD_N-GLC_1	422	427	PF02516	0.664
MOD_N-GLC_2	744	746	PF02516	0.543
MOD_NEK2_1	241	246	PF00069	0.783
MOD_NEK2_1	311	316	PF00069	0.575
MOD_NEK2_1	444	449	PF00069	0.553
MOD_NEK2_1	554	559	PF00069	0.385
MOD_NEK2_1	573	578	PF00069	0.438
MOD_NEK2_1	769	774	PF00069	0.520
MOD_NEK2_1	865	870	PF00069	0.696
MOD_NEK2_1	942	947	PF00069	0.539
MOD_NEK2_2	364	369	PF00069	0.657
MOD_PIKK_1	139	145	PF00454	0.627
MOD_PIKK_1	369	375	PF00454	0.732
MOD_PIKK_1	423	429	PF00454	0.699
MOD_PIKK_1	478	484	PF00454	0.660
MOD_PIKK_1	56	62	PF00454	0.659
MOD_PIKK_1	581	587	PF00454	0.569
MOD_PIKK_1	744	750	PF00454	0.647
MOD_PK_1	144	150	PF00069	0.663
MOD_PK_1	69	75	PF00069	0.574
MOD_PKA_1	144	150	PF00069	0.621
MOD_PKA_2	144	150	PF00069	0.681
MOD_PKA_2	266	272	PF00069	0.688
MOD_PKA_2	328	334	PF00069	0.782
MOD_PKA_2	338	344	PF00069	0.530
MOD_PKA_2	419	425	PF00069	0.612
MOD_PKA_2	451	457	PF00069	0.601
MOD_PKA_2	468	474	PF00069	0.473
MOD_PKA_2	579	585	PF00069	0.465
MOD_PKA_2	682	688	PF00069	0.418
MOD_PKA_2	812	818	PF00069	0.639
MOD_Plk_1	173	179	PF00069	0.583
MOD_Plk_1	239	245	PF00069	0.610
MOD_Plk_1	554	560	PF00069	0.481
MOD_Plk_1	744	750	PF00069	0.545
MOD_Plk_1	872	878	PF00069	0.537
MOD_Plk_1	887	893	PF00069	0.649
MOD_Plk_2-3	916	922	PF00069	0.684
MOD_Plk_4	102	108	PF00069	0.625
MOD_Plk_4	173	179	PF00069	0.672
MOD_Plk_4	227	233	PF00069	0.669
MOD_Plk_4	439	445	PF00069	0.692
MOD_Plk_4	641	647	PF00069	0.627
MOD_Plk_4	668	674	PF00069	0.467
MOD_Plk_4	794	800	PF00069	0.433
MOD_Plk_4	80	86	PF00069	0.521
MOD_Plk_4	887	893	PF00069	0.608
MOD_Plk_4	942	948	PF00069	0.627
MOD_ProDKin_1	157	163	PF00069	0.710
MOD_ProDKin_1	231	237	PF00069	0.641
MOD_ProDKin_1	726	732	PF00069	0.594
MOD_ProDKin_1	835	841	PF00069	0.550
MOD_SUMO_for_1	43	46	PF00179	0.552
MOD_SUMO_for_1	912	915	PF00179	0.575
MOD_SUMO_rev_2	301	307	PF00179	0.478
MOD_SUMO_rev_2	321	327	PF00179	0.521
MOD_SUMO_rev_2	620	627	PF00179	0.396
TRG_DiLeu_BaEn_1	861	866	PF01217	0.696
TRG_DiLeu_BaEn_2	497	503	PF01217	0.378
TRG_DiLeu_BaEn_4	402	408	PF01217	0.576
TRG_DiLeu_BaLyEn_6	273	278	PF01217	0.672
TRG_DiLeu_BaLyEn_6	719	724	PF01217	0.403
TRG_DiLeu_BaLyEn_6	84	89	PF01217	0.602
TRG_ENDOCYTIC_2	390	393	PF00928	0.676
TRG_ENDOCYTIC_2	445	448	PF00928	0.655
TRG_ENDOCYTIC_2	535	538	PF00928	0.391
TRG_ENDOCYTIC_2	628	631	PF00928	0.498
TRG_ENDOCYTIC_2	700	703	PF00928	0.481
TRG_ENDOCYTIC_2	766	769	PF00928	0.595
TRG_ER_diArg_1	144	146	PF00400	0.625
TRG_ER_diArg_1	222	225	PF00400	0.591
TRG_ER_diArg_1	275	277	PF00400	0.679
TRG_ER_diArg_1	285	288	PF00400	0.349
TRG_ER_diArg_1	449	452	PF00400	0.671
TRG_ER_diArg_1	51	53	PF00400	0.659
TRG_ER_diArg_1	528	530	PF00400	0.443
TRG_ER_diArg_1	579	581	PF00400	0.449
TRG_ER_diArg_1	721	723	PF00400	0.433
TRG_ER_diArg_1	786	788	PF00400	0.499
TRG_NES_CRM1_1	620	635	PF08389	0.423
TRG_NLS_Bipartite_1	275	289	PF00514	0.559
TRG_NLS_MonoExtN_4	394	399	PF00514	0.651
TRG_Pf-PMV_PEXEL_1	499	504	PF00026	0.602
TRG_Pf-PMV_PEXEL_1	528	532	PF00026	0.433
TRG_Pf-PMV_PEXEL_1	556	560	PF00026	0.439
TRG_Pf-PMV_PEXEL_1	619	624	PF00026	0.398

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PC02	Leptomonas seymouri	40%	97%
A0A3S7X4E6	Leishmania donovani	86%	100%
A4HJ82	Leishmania braziliensis	60%	100%
A4I6M6	Leishmania infantum	86%	100%
E9B1P9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	100%