Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q6F5_LEIMA

TriTrypDb:

LmjF.31.1080 , LMJLV39_310017100 , LMJSD75_310016700

Length:

974

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q6F5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q6F5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	171	175	PF00656	0.592
CLV_C14_Caspase3-7	237	241	PF00656	0.613
CLV_NRD_NRD_1	130	132	PF00675	0.716
CLV_NRD_NRD_1	136	138	PF00675	0.579
CLV_NRD_NRD_1	37	39	PF00675	0.729
CLV_NRD_NRD_1	70	72	PF00675	0.808
CLV_NRD_NRD_1	87	89	PF00675	0.490
CLV_NRD_NRD_1	95	97	PF00675	0.674
CLV_NRD_NRD_1	966	968	PF00675	0.764
CLV_NRD_NRD_1	972	974	PF00675	0.709
CLV_PCSK_FUR_1	67	71	PF00082	0.672
CLV_PCSK_KEX2_1	130	132	PF00082	0.716
CLV_PCSK_KEX2_1	136	138	PF00082	0.579
CLV_PCSK_KEX2_1	37	39	PF00082	0.786
CLV_PCSK_KEX2_1	69	71	PF00082	0.814
CLV_PCSK_KEX2_1	87	89	PF00082	0.474
CLV_PCSK_KEX2_1	95	97	PF00082	0.674
CLV_PCSK_KEX2_1	972	974	PF00082	0.789
CLV_PCSK_SKI1_1	225	229	PF00082	0.651
CLV_PCSK_SKI1_1	427	431	PF00082	0.609
CLV_PCSK_SKI1_1	492	496	PF00082	0.627
CLV_PCSK_SKI1_1	73	77	PF00082	0.606
CLV_PCSK_SKI1_1	87	91	PF00082	0.586
CLV_PCSK_SKI1_1	918	922	PF00082	0.776
DEG_APCC_DBOX_1	245	253	PF00400	0.516
DEG_APCC_DBOX_1	72	80	PF00400	0.573
DEG_SCF_FBW7_1	514	521	PF00400	0.649
DEG_SPOP_SBC_1	263	267	PF00917	0.598
DEG_SPOP_SBC_1	274	278	PF00917	0.637
DEG_SPOP_SBC_1	287	291	PF00917	0.704
DEG_SPOP_SBC_1	530	534	PF00917	0.637
DEG_SPOP_SBC_1	547	551	PF00917	0.606
DEG_SPOP_SBC_1	582	586	PF00917	0.684
DEG_SPOP_SBC_1	619	623	PF00917	0.740
DOC_CKS1_1	390	395	PF01111	0.679
DOC_CKS1_1	493	498	PF01111	0.686
DOC_CKS1_1	682	687	PF01111	0.596
DOC_CKS1_1	774	779	PF01111	0.590
DOC_CYCLIN_yCln2_LP_2	490	496	PF00134	0.612
DOC_MAPK_gen_1	187	195	PF00069	0.539
DOC_MAPK_MEF2A_6	187	195	PF00069	0.606
DOC_MAPK_MEF2A_6	3	10	PF00069	0.707
DOC_PP1_RVXF_1	456	463	PF00149	0.584
DOC_PP4_FxxP_1	386	389	PF00568	0.718
DOC_PP4_FxxP_1	390	393	PF00568	0.677
DOC_PP4_FxxP_1	928	931	PF00568	0.764
DOC_PP4_MxPP_1	789	792	PF00568	0.709
DOC_USP7_MATH_1	112	116	PF00917	0.717
DOC_USP7_MATH_1	264	268	PF00917	0.746
DOC_USP7_MATH_1	272	276	PF00917	0.701
DOC_USP7_MATH_1	287	291	PF00917	0.793
DOC_USP7_MATH_1	319	323	PF00917	0.751
DOC_USP7_MATH_1	324	328	PF00917	0.686
DOC_USP7_MATH_1	36	40	PF00917	0.637
DOC_USP7_MATH_1	377	381	PF00917	0.651
DOC_USP7_MATH_1	397	401	PF00917	0.678
DOC_USP7_MATH_1	432	436	PF00917	0.711
DOC_USP7_MATH_1	440	444	PF00917	0.586
DOC_USP7_MATH_1	446	450	PF00917	0.540
DOC_USP7_MATH_1	483	487	PF00917	0.673
DOC_USP7_MATH_1	498	502	PF00917	0.549
DOC_USP7_MATH_1	512	516	PF00917	0.580
DOC_USP7_MATH_1	546	550	PF00917	0.712
DOC_USP7_MATH_1	582	586	PF00917	0.644
DOC_USP7_MATH_1	657	661	PF00917	0.711
DOC_USP7_MATH_1	668	672	PF00917	0.576
DOC_USP7_MATH_1	695	699	PF00917	0.727
DOC_USP7_MATH_1	711	715	PF00917	0.645
DOC_USP7_MATH_1	718	722	PF00917	0.667
DOC_USP7_MATH_1	727	731	PF00917	0.560
DOC_USP7_MATH_1	738	742	PF00917	0.558
DOC_USP7_MATH_1	746	750	PF00917	0.526
DOC_USP7_MATH_1	806	810	PF00917	0.574
DOC_USP7_MATH_1	838	842	PF00917	0.633
DOC_USP7_MATH_1	863	867	PF00917	0.738
DOC_USP7_MATH_1	873	877	PF00917	0.652
DOC_USP7_MATH_1	911	915	PF00917	0.755
DOC_USP7_MATH_1	916	920	PF00917	0.728
DOC_USP7_UBL2_3	350	354	PF12436	0.643
DOC_WW_Pin1_4	270	275	PF00397	0.724
DOC_WW_Pin1_4	277	282	PF00397	0.640
DOC_WW_Pin1_4	322	327	PF00397	0.783
DOC_WW_Pin1_4	389	394	PF00397	0.741
DOC_WW_Pin1_4	492	497	PF00397	0.693
DOC_WW_Pin1_4	514	519	PF00397	0.731
DOC_WW_Pin1_4	548	553	PF00397	0.643
DOC_WW_Pin1_4	559	564	PF00397	0.632
DOC_WW_Pin1_4	620	625	PF00397	0.772
DOC_WW_Pin1_4	646	651	PF00397	0.709
DOC_WW_Pin1_4	681	686	PF00397	0.637
DOC_WW_Pin1_4	691	696	PF00397	0.649
DOC_WW_Pin1_4	730	735	PF00397	0.739
DOC_WW_Pin1_4	773	778	PF00397	0.589
DOC_WW_Pin1_4	906	911	PF00397	0.783
DOC_WW_Pin1_4	932	937	PF00397	0.772
DOC_WW_Pin1_4	96	101	PF00397	0.667
LIG_14-3-3_CanoR_1	101	107	PF00244	0.676
LIG_14-3-3_CanoR_1	262	272	PF00244	0.613
LIG_14-3-3_CanoR_1	37	43	PF00244	0.729
LIG_14-3-3_CanoR_1	56	61	PF00244	0.601
LIG_BIR_II_1	1	5	PF00653	0.720
LIG_BRCT_BRCA1_1	145	149	PF00533	0.615
LIG_BRCT_BRCA1_1	290	294	PF00533	0.701
LIG_BRCT_BRCA1_1	440	444	PF00533	0.623
LIG_BRCT_BRCA1_1	483	487	PF00533	0.755
LIG_BRCT_BRCA1_1	609	613	PF00533	0.705
LIG_BRCT_BRCA1_1	692	696	PF00533	0.722
LIG_BRCT_BRCA1_1	713	717	PF00533	0.775
LIG_BRCT_BRCA1_1	735	739	PF00533	0.685
LIG_BRCT_BRCA1_1	764	768	PF00533	0.746
LIG_BRCT_BRCA1_1	839	843	PF00533	0.605
LIG_BRCT_BRCA1_1	860	864	PF00533	0.776
LIG_BRCT_BRCA1_1	934	938	PF00533	0.776
LIG_EH_1	387	391	PF12763	0.740
LIG_EH_1	401	405	PF12763	0.632
LIG_EH_1	539	543	PF12763	0.766
LIG_FHA_1	165	171	PF00498	0.599
LIG_FHA_1	410	416	PF00498	0.620
LIG_FHA_1	465	471	PF00498	0.665
LIG_FHA_1	956	962	PF00498	0.767
LIG_FHA_2	365	371	PF00498	0.695
LIG_LIR_Apic_2	387	393	PF02991	0.704
LIG_LIR_Gen_1	197	206	PF02991	0.655
LIG_LIR_Gen_1	484	494	PF02991	0.706
LIG_LIR_Nem_3	11	16	PF02991	0.762
LIG_LIR_Nem_3	197	202	PF02991	0.661
LIG_LIR_Nem_3	484	490	PF02991	0.705
LIG_LIR_Nem_3	610	616	PF02991	0.705
LIG_PCNA_yPIPBox_3	153	166	PF02747	0.631
LIG_Pex14_2	386	390	PF04695	0.720
LIG_SH2_CRK	199	203	PF00017	0.605
LIG_SH2_NCK_1	199	203	PF00017	0.605
LIG_SH2_STAP1	199	203	PF00017	0.605
LIG_SH3_3	278	284	PF00018	0.722
LIG_SH3_3	28	34	PF00018	0.785
LIG_SH3_3	490	496	PF00018	0.695
LIG_SH3_3	538	544	PF00018	0.765
LIG_SH3_3	549	555	PF00018	0.608
LIG_SH3_3	613	619	PF00018	0.776
LIG_SH3_3	771	777	PF00018	0.623
LIG_SH3_3	788	794	PF00018	0.701
LIG_SH3_3	813	819	PF00018	0.571
LIG_SH3_4	350	357	PF00018	0.647
LIG_SUMO_SIM_anti_2	102	111	PF11976	0.719
MOD_CDK_SPK_2	548	553	PF00069	0.667
MOD_CDK_SPK_2	96	101	PF00069	0.667
MOD_CDK_SPxxK_3	96	103	PF00069	0.670
MOD_CK1_1	115	121	PF00069	0.727
MOD_CK1_1	204	210	PF00069	0.574
MOD_CK1_1	273	279	PF00069	0.720
MOD_CK1_1	289	295	PF00069	0.768
MOD_CK1_1	307	313	PF00069	0.516
MOD_CK1_1	322	328	PF00069	0.617
MOD_CK1_1	375	381	PF00069	0.780
MOD_CK1_1	4	10	PF00069	0.722
MOD_CK1_1	409	415	PF00069	0.636
MOD_CK1_1	431	437	PF00069	0.728
MOD_CK1_1	48	54	PF00069	0.750
MOD_CK1_1	502	508	PF00069	0.723
MOD_CK1_1	521	527	PF00069	0.529
MOD_CK1_1	575	581	PF00069	0.749
MOD_CK1_1	591	597	PF00069	0.572
MOD_CK1_1	600	606	PF00069	0.685
MOD_CK1_1	608	614	PF00069	0.567
MOD_CK1_1	637	643	PF00069	0.768
MOD_CK1_1	661	667	PF00069	0.758
MOD_CK1_1	669	675	PF00069	0.652
MOD_CK1_1	698	704	PF00069	0.733
MOD_CK1_1	730	736	PF00069	0.723
MOD_CK1_1	766	772	PF00069	0.644
MOD_CK1_1	828	834	PF00069	0.752
MOD_CK1_1	858	864	PF00069	0.775
MOD_CK1_1	866	872	PF00069	0.656
MOD_CK1_1	914	920	PF00069	0.690
MOD_CK1_1	955	961	PF00069	0.772
MOD_CK1_1	963	969	PF00069	0.666
MOD_CK1_1	99	105	PF00069	0.777
MOD_CK2_1	191	197	PF00069	0.554
MOD_CK2_1	215	221	PF00069	0.611
MOD_CK2_1	227	233	PF00069	0.516
MOD_CK2_1	364	370	PF00069	0.697
MOD_DYRK1A_RPxSP_1	96	100	PF00069	0.664
MOD_GlcNHglycan	183	187	PF01048	0.535
MOD_GlcNHglycan	210	213	PF01048	0.552
MOD_GlcNHglycan	309	312	PF01048	0.700
MOD_GlcNHglycan	314	317	PF01048	0.692
MOD_GlcNHglycan	326	329	PF01048	0.600
MOD_GlcNHglycan	339	342	PF01048	0.585
MOD_GlcNHglycan	375	378	PF01048	0.686
MOD_GlcNHglycan	379	382	PF01048	0.658
MOD_GlcNHglycan	399	402	PF01048	0.675
MOD_GlcNHglycan	408	411	PF01048	0.654
MOD_GlcNHglycan	430	433	PF01048	0.685
MOD_GlcNHglycan	434	437	PF01048	0.649
MOD_GlcNHglycan	448	451	PF01048	0.576
MOD_GlcNHglycan	501	504	PF01048	0.821
MOD_GlcNHglycan	514	517	PF01048	0.607
MOD_GlcNHglycan	518	521	PF01048	0.555
MOD_GlcNHglycan	526	529	PF01048	0.623
MOD_GlcNHglycan	533	536	PF01048	0.554
MOD_GlcNHglycan	574	577	PF01048	0.690
MOD_GlcNHglycan	593	596	PF01048	0.535
MOD_GlcNHglycan	599	602	PF01048	0.734
MOD_GlcNHglycan	604	607	PF01048	0.650
MOD_GlcNHglycan	610	613	PF01048	0.513
MOD_GlcNHglycan	668	671	PF01048	0.642
MOD_GlcNHglycan	673	676	PF01048	0.576
MOD_GlcNHglycan	677	680	PF01048	0.674
MOD_GlcNHglycan	686	689	PF01048	0.559
MOD_GlcNHglycan	720	723	PF01048	0.682
MOD_GlcNHglycan	725	728	PF01048	0.698
MOD_GlcNHglycan	729	732	PF01048	0.643
MOD_GlcNHglycan	735	738	PF01048	0.638
MOD_GlcNHglycan	740	743	PF01048	0.588
MOD_GlcNHglycan	748	751	PF01048	0.519
MOD_GlcNHglycan	808	811	PF01048	0.660
MOD_GlcNHglycan	827	830	PF01048	0.623
MOD_GlcNHglycan	845	848	PF01048	0.526
MOD_GlcNHglycan	857	860	PF01048	0.609
MOD_GlcNHglycan	879	882	PF01048	0.764
MOD_GlcNHglycan	913	916	PF01048	0.691
MOD_GlcNHglycan	918	921	PF01048	0.650
MOD_GSK3_1	114	121	PF00069	0.787
MOD_GSK3_1	143	150	PF00069	0.663
MOD_GSK3_1	204	211	PF00069	0.549
MOD_GSK3_1	234	241	PF00069	0.666
MOD_GSK3_1	258	265	PF00069	0.612
MOD_GSK3_1	270	277	PF00069	0.773
MOD_GSK3_1	303	310	PF00069	0.746
MOD_GSK3_1	318	325	PF00069	0.612
MOD_GSK3_1	326	333	PF00069	0.679
MOD_GSK3_1	364	371	PF00069	0.759
MOD_GSK3_1	372	379	PF00069	0.730
MOD_GSK3_1	388	395	PF00069	0.583
MOD_GSK3_1	402	409	PF00069	0.667
MOD_GSK3_1	427	434	PF00069	0.727
MOD_GSK3_1	479	486	PF00069	0.731
MOD_GSK3_1	48	55	PF00069	0.817
MOD_GSK3_1	498	505	PF00069	0.753
MOD_GSK3_1	512	519	PF00069	0.565
MOD_GSK3_1	524	531	PF00069	0.630
MOD_GSK3_1	56	63	PF00069	0.699
MOD_GSK3_1	571	578	PF00069	0.742
MOD_GSK3_1	584	591	PF00069	0.619
MOD_GSK3_1	597	604	PF00069	0.593
MOD_GSK3_1	618	625	PF00069	0.742
MOD_GSK3_1	634	641	PF00069	0.554
MOD_GSK3_1	657	664	PF00069	0.762
MOD_GSK3_1	669	676	PF00069	0.610
MOD_GSK3_1	691	698	PF00069	0.714
MOD_GSK3_1	712	719	PF00069	0.724
MOD_GSK3_1	723	730	PF00069	0.623
MOD_GSK3_1	733	740	PF00069	0.641
MOD_GSK3_1	762	769	PF00069	0.643
MOD_GSK3_1	802	809	PF00069	0.645
MOD_GSK3_1	821	828	PF00069	0.601
MOD_GSK3_1	833	840	PF00069	0.603
MOD_GSK3_1	855	862	PF00069	0.670
MOD_GSK3_1	873	880	PF00069	0.609
MOD_GSK3_1	952	959	PF00069	0.755
MOD_N-GLC_1	123	128	PF02516	0.559
MOD_N-GLC_1	191	196	PF02516	0.530
MOD_N-GLC_1	365	370	PF02516	0.654
MOD_N-GLC_1	372	377	PF02516	0.677
MOD_N-GLC_1	45	50	PF02516	0.783
MOD_N-GLC_1	646	651	PF02516	0.702
MOD_N-GLC_1	690	695	PF02516	0.747
MOD_N-GLC_1	855	860	PF02516	0.765
MOD_N-GLC_1	866	871	PF02516	0.613
MOD_N-GLC_2	299	301	PF02516	0.690
MOD_NEK2_1	1	6	PF00069	0.736
MOD_NEK2_1	165	170	PF00069	0.600
MOD_NEK2_1	191	196	PF00069	0.547
MOD_NEK2_1	206	211	PF00069	0.448
MOD_NEK2_1	227	232	PF00069	0.664
MOD_NEK2_1	337	342	PF00069	0.713
MOD_NEK2_1	406	411	PF00069	0.766
MOD_NEK2_1	428	433	PF00069	0.576
MOD_NEK2_1	439	444	PF00069	0.498
MOD_NEK2_1	523	528	PF00069	0.723
MOD_NEK2_1	588	593	PF00069	0.741
MOD_NEK2_1	638	643	PF00069	0.771
MOD_NEK2_1	662	667	PF00069	0.597
MOD_NEK2_1	696	701	PF00069	0.657
MOD_NEK2_1	712	717	PF00069	0.620
MOD_NEK2_1	843	848	PF00069	0.697
MOD_NEK2_1	855	860	PF00069	0.615
MOD_NEK2_1	877	882	PF00069	0.718
MOD_NEK2_1	961	966	PF00069	0.721
MOD_NEK2_2	838	843	PF00069	0.607
MOD_NEK2_2	873	878	PF00069	0.732
MOD_PIKK_1	1	7	PF00454	0.716
MOD_PIKK_1	926	932	PF00454	0.732
MOD_PIKK_1	952	958	PF00454	0.697
MOD_PK_1	56	62	PF00069	0.592
MOD_PKA_1	37	43	PF00069	0.645
MOD_PKA_2	102	108	PF00069	0.773
MOD_PKA_2	238	244	PF00069	0.597
MOD_PKA_2	36	42	PF00069	0.723
MOD_PKA_2	608	614	PF00069	0.651
MOD_Plk_1	115	121	PF00069	0.737
MOD_Plk_1	191	197	PF00069	0.533
MOD_Plk_1	215	221	PF00069	0.611
MOD_Plk_4	102	108	PF00069	0.773
MOD_Plk_4	238	244	PF00069	0.597
MOD_Plk_4	56	62	PF00069	0.792
MOD_Plk_4	763	769	PF00069	0.647
MOD_Plk_4	838	844	PF00069	0.757
MOD_Plk_4	873	879	PF00069	0.764
MOD_Plk_4	956	962	PF00069	0.776
MOD_ProDKin_1	270	276	PF00069	0.723
MOD_ProDKin_1	277	283	PF00069	0.638
MOD_ProDKin_1	322	328	PF00069	0.783
MOD_ProDKin_1	389	395	PF00069	0.740
MOD_ProDKin_1	492	498	PF00069	0.692
MOD_ProDKin_1	514	520	PF00069	0.733
MOD_ProDKin_1	548	554	PF00069	0.636
MOD_ProDKin_1	559	565	PF00069	0.633
MOD_ProDKin_1	620	626	PF00069	0.772
MOD_ProDKin_1	646	652	PF00069	0.709
MOD_ProDKin_1	681	687	PF00069	0.637
MOD_ProDKin_1	691	697	PF00069	0.650
MOD_ProDKin_1	730	736	PF00069	0.739
MOD_ProDKin_1	773	779	PF00069	0.592
MOD_ProDKin_1	906	912	PF00069	0.782
MOD_ProDKin_1	932	938	PF00069	0.775
MOD_ProDKin_1	96	102	PF00069	0.668
MOD_SUMO_for_1	107	110	PF00179	0.684
MOD_SUMO_for_1	186	189	PF00179	0.574
MOD_SUMO_for_1	250	253	PF00179	0.527
MOD_SUMO_rev_2	230	237	PF00179	0.659
TRG_DiLeu_BaEn_4	215	221	PF01217	0.611
TRG_ENDOCYTIC_2	199	202	PF00928	0.610
TRG_ENDOCYTIC_2	203	206	PF00928	0.541
TRG_ER_diArg_1	100	103	PF00400	0.671
TRG_ER_diArg_1	135	137	PF00400	0.659
TRG_ER_diArg_1	29	32	PF00400	0.786
TRG_ER_diArg_1	36	38	PF00400	0.734
TRG_ER_diArg_1	66	69	PF00400	0.812
TRG_ER_diArg_1	70	73	PF00400	0.762
TRG_ER_diArg_1	971	973	PF00400	0.775
TRG_NES_CRM1_1	183	197	PF08389	0.604
TRG_NLS_MonoExtC_3	966	971	PF00514	0.762
TRG_Pf-PMV_PEXEL_1	153	158	PF00026	0.447
TRG_Pf-PMV_PEXEL_1	88	93	PF00026	0.687

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X4C6	Leishmania donovani	86%	100%
A4HJ89	Leishmania braziliensis	63%	100%
A4I6N2	Leishmania infantum	86%	100%
E9B1Q5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%