Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q6B5_LEIMA

TriTrypDb:

LmjF.31.1470 , LMJLV39_310022500 , LMJSD75_310021800

Length:

1041

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q6B5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q6B5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	425	429	PF00656	0.682
CLV_C14_Caspase3-7	950	954	PF00656	0.631
CLV_NRD_NRD_1	282	284	PF00675	0.674
CLV_NRD_NRD_1	36	38	PF00675	0.775
CLV_NRD_NRD_1	437	439	PF00675	0.596
CLV_NRD_NRD_1	459	461	PF00675	0.601
CLV_NRD_NRD_1	805	807	PF00675	0.699
CLV_NRD_NRD_1	842	844	PF00675	0.732
CLV_PCSK_FUR_1	280	284	PF00082	0.629
CLV_PCSK_KEX2_1	282	284	PF00082	0.674
CLV_PCSK_KEX2_1	36	38	PF00082	0.796
CLV_PCSK_KEX2_1	437	439	PF00082	0.670
CLV_PCSK_KEX2_1	459	461	PF00082	0.601
CLV_PCSK_KEX2_1	805	807	PF00082	0.699
CLV_PCSK_PC7_1	278	284	PF00082	0.657
CLV_PCSK_SKI1_1	101	105	PF00082	0.730
CLV_PCSK_SKI1_1	124	128	PF00082	0.680
CLV_PCSK_SKI1_1	168	172	PF00082	0.529
CLV_PCSK_SKI1_1	175	179	PF00082	0.493
CLV_PCSK_SKI1_1	327	331	PF00082	0.660
CLV_PCSK_SKI1_1	597	601	PF00082	0.844
CLV_PCSK_SKI1_1	823	827	PF00082	0.581
CLV_PCSK_SKI1_1	957	961	PF00082	0.693
CLV_Separin_Metazoa	820	824	PF03568	0.643
DEG_APCC_DBOX_1	282	290	PF00400	0.624
DEG_COP1_1	81	91	PF00400	0.786
DEG_Nend_Nbox_1	1	3	PF02207	0.784
DEG_SPOP_SBC_1	105	109	PF00917	0.694
DEG_SPOP_SBC_1	422	426	PF00917	0.587
DOC_ANK_TNKS_1	832	839	PF00023	0.688
DOC_CKS1_1	143	148	PF01111	0.598
DOC_CYCLIN_RxL_1	97	108	PF00134	0.730
DOC_CYCLIN_yCln2_LP_2	386	392	PF00134	0.646
DOC_CYCLIN_yCln2_LP_2	720	726	PF00134	0.779
DOC_MAPK_JIP1_4	554	560	PF00069	0.539
DOC_PP1_RVXF_1	877	884	PF00149	0.647
DOC_PP2B_LxvP_1	853	856	PF13499	0.655
DOC_PP4_FxxP_1	492	495	PF00568	0.628
DOC_PP4_FxxP_1	790	793	PF00568	0.776
DOC_PP4_FxxP_1	890	893	PF00568	0.638
DOC_USP7_MATH_1	105	109	PF00917	0.635
DOC_USP7_MATH_1	139	143	PF00917	0.723
DOC_USP7_MATH_1	222	226	PF00917	0.776
DOC_USP7_MATH_1	240	244	PF00917	0.592
DOC_USP7_MATH_1	422	426	PF00917	0.809
DOC_USP7_MATH_1	431	435	PF00917	0.698
DOC_USP7_MATH_1	467	471	PF00917	0.742
DOC_USP7_MATH_1	50	54	PF00917	0.730
DOC_USP7_MATH_1	512	516	PF00917	0.769
DOC_USP7_MATH_1	541	545	PF00917	0.714
DOC_USP7_MATH_1	646	650	PF00917	0.746
DOC_USP7_MATH_1	661	665	PF00917	0.713
DOC_USP7_MATH_1	796	800	PF00917	0.729
DOC_USP7_MATH_1	943	947	PF00917	0.675
DOC_USP7_MATH_1	977	981	PF00917	0.757
DOC_USP7_MATH_2	956	962	PF00917	0.611
DOC_WW_Pin1_4	142	147	PF00397	0.676
DOC_WW_Pin1_4	151	156	PF00397	0.583
DOC_WW_Pin1_4	22	27	PF00397	0.770
DOC_WW_Pin1_4	267	272	PF00397	0.759
DOC_WW_Pin1_4	45	50	PF00397	0.724
DOC_WW_Pin1_4	470	475	PF00397	0.691
DOC_WW_Pin1_4	642	647	PF00397	0.765
DOC_WW_Pin1_4	659	664	PF00397	0.676
DOC_WW_Pin1_4	667	672	PF00397	0.606
DOC_WW_Pin1_4	68	73	PF00397	0.798
DOC_WW_Pin1_4	683	688	PF00397	0.561
DOC_WW_Pin1_4	808	813	PF00397	0.776
DOC_WW_Pin1_4	832	837	PF00397	0.687
DOC_WW_Pin1_4	847	852	PF00397	0.727
DOC_WW_Pin1_4	89	94	PF00397	0.665
DOC_WW_Pin1_4	899	904	PF00397	0.643
DOC_WW_Pin1_4	964	969	PF00397	0.773
LIG_14-3-3_CanoR_1	124	132	PF00244	0.798
LIG_14-3-3_CanoR_1	201	207	PF00244	0.437
LIG_14-3-3_CanoR_1	292	300	PF00244	0.620
LIG_14-3-3_CanoR_1	369	376	PF00244	0.627
LIG_14-3-3_CanoR_1	432	436	PF00244	0.587
LIG_14-3-3_CanoR_1	453	461	PF00244	0.648
LIG_14-3-3_CanoR_1	465	474	PF00244	0.566
LIG_14-3-3_CanoR_1	578	582	PF00244	0.559
LIG_14-3-3_CanoR_1	795	801	PF00244	0.791
LIG_14-3-3_CanoR_1	854	864	PF00244	0.729
LIG_14-3-3_CanoR_1	898	903	PF00244	0.711
LIG_14-3-3_CanoR_1	981	987	PF00244	0.679
LIG_Actin_WH2_2	153	170	PF00022	0.649
LIG_Actin_WH2_2	712	727	PF00022	0.755
LIG_BRCT_BRCA1_1	153	157	PF00533	0.669
LIG_BRCT_BRCA1_1	768	772	PF00533	0.697
LIG_BRCT_BRCA1_1	901	905	PF00533	0.670
LIG_BRCT_BRCA1_1	918	922	PF00533	0.485
LIG_BRCT_BRCA1_2	918	924	PF00533	0.669
LIG_CSL_BTD_1	335	338	PF09270	0.503
LIG_CtBP_PxDLS_1	671	675	PF00389	0.731
LIG_deltaCOP1_diTrp_1	880	890	PF00928	0.712
LIG_eIF4E_1	904	910	PF01652	0.598
LIG_FHA_1	1005	1011	PF00498	0.606
LIG_FHA_1	203	209	PF00498	0.599
LIG_FHA_1	391	397	PF00498	0.622
LIG_FHA_1	4	10	PF00498	0.768
LIG_FHA_1	633	639	PF00498	0.762
LIG_FHA_1	643	649	PF00498	0.684
LIG_FHA_1	98	104	PF00498	0.625
LIG_FHA_2	482	488	PF00498	0.595
LIG_FHA_2	69	75	PF00498	0.795
LIG_FHA_2	704	710	PF00498	0.653
LIG_FHA_2	782	788	PF00498	0.644
LIG_LIR_Apic_2	140	146	PF02991	0.749
LIG_LIR_Apic_2	19	23	PF02991	0.692
LIG_LIR_Apic_2	490	495	PF02991	0.640
LIG_LIR_Apic_2	787	793	PF02991	0.740
LIG_LIR_Apic_2	901	907	PF02991	0.632
LIG_LIR_Gen_1	154	164	PF02991	0.440
LIG_LIR_Gen_1	398	404	PF02991	0.501
LIG_LIR_Gen_1	476	483	PF02991	0.615
LIG_LIR_Gen_1	799	808	PF02991	0.718
LIG_LIR_Gen_1	81	89	PF02991	0.791
LIG_LIR_Nem_3	154	160	PF02991	0.623
LIG_LIR_Nem_3	334	339	PF02991	0.535
LIG_LIR_Nem_3	398	403	PF02991	0.523
LIG_LIR_Nem_3	476	482	PF02991	0.616
LIG_LIR_Nem_3	799	803	PF02991	0.711
LIG_LIR_Nem_3	81	85	PF02991	0.791
LIG_LIR_Nem_3	880	886	PF02991	0.704
LIG_LIR_Nem_3	941	945	PF02991	0.569
LIG_MLH1_MIPbox_1	153	157	PF16413	0.514
LIG_MLH1_MIPbox_1	901	905	PF16413	0.658
LIG_MYND_1	683	687	PF01753	0.700
LIG_NRP_CendR_1	1040	1041	PF00754	0.710
LIG_Pex14_1	98	102	PF04695	0.538
LIG_RPA_C_Fungi	455	467	PF08784	0.674
LIG_SH2_CRK	1012	1016	PF00017	0.580
LIG_SH2_CRK	564	568	PF00017	0.608
LIG_SH2_NCK_1	143	147	PF00017	0.759
LIG_SH2_NCK_1	564	568	PF00017	0.476
LIG_SH2_NCK_1	974	978	PF00017	0.549
LIG_SH2_PTP2	20	23	PF00017	0.769
LIG_SH2_SRC	20	23	PF00017	0.769
LIG_SH2_SRC	777	780	PF00017	0.620
LIG_SH2_STAP1	381	385	PF00017	0.544
LIG_SH2_STAT3	581	584	PF00017	0.668
LIG_SH2_STAT5	102	105	PF00017	0.626
LIG_SH2_STAT5	1020	1023	PF00017	0.660
LIG_SH2_STAT5	20	23	PF00017	0.769
LIG_SH2_STAT5	203	206	PF00017	0.517
LIG_SH2_STAT5	33	36	PF00017	0.575
LIG_SH2_STAT5	581	584	PF00017	0.668
LIG_SH2_STAT5	904	907	PF00017	0.619
LIG_SH3_1	20	26	PF00018	0.773
LIG_SH3_2	224	229	PF14604	0.621
LIG_SH3_3	20	26	PF00018	0.773
LIG_SH3_3	221	227	PF00018	0.616
LIG_SH3_3	310	316	PF00018	0.635
LIG_SH3_3	325	331	PF00018	0.642
LIG_SH3_3	332	338	PF00018	0.653
LIG_SH3_3	547	553	PF00018	0.700
LIG_SH3_3	748	754	PF00018	0.738
LIG_SH3_3	790	796	PF00018	0.556
LIG_SH3_3	807	813	PF00018	0.500
LIG_SH3_3	937	943	PF00018	0.749
LIG_SH3_3	946	952	PF00018	0.662
LIG_SUMO_SIM_par_1	338	345	PF11976	0.598
LIG_SUMO_SIM_par_1	635	645	PF11976	0.767
LIG_SUMO_SIM_par_1	669	675	PF11976	0.726
LIG_TRAF2_1	976	979	PF00917	0.623
LIG_TRAF2_2	271	276	PF00917	0.735
LIG_TRAF2_2	49	54	PF00917	0.703
LIG_TYR_ITIM	1010	1015	PF00017	0.571
LIG_TYR_ITIM	724	729	PF00017	0.551
LIG_WRC_WIRS_1	82	87	PF05994	0.716
MOD_CDK_SPxxK_3	142	149	PF00069	0.669
MOD_CDK_SPxxK_3	267	274	PF00069	0.602
MOD_CDK_SPxxK_3	45	52	PF00069	0.816
MOD_CDK_SPxxK_3	847	854	PF00069	0.618
MOD_CK1_1	107	113	PF00069	0.718
MOD_CK1_1	142	148	PF00069	0.607
MOD_CK1_1	159	165	PF00069	0.627
MOD_CK1_1	16	22	PF00069	0.675
MOD_CK1_1	207	213	PF00069	0.508
MOD_CK1_1	267	273	PF00069	0.821
MOD_CK1_1	345	351	PF00069	0.669
MOD_CK1_1	371	377	PF00069	0.664
MOD_CK1_1	411	417	PF00069	0.684
MOD_CK1_1	424	430	PF00069	0.683
MOD_CK1_1	447	453	PF00069	0.748
MOD_CK1_1	468	474	PF00069	0.746
MOD_CK1_1	546	552	PF00069	0.702
MOD_CK1_1	591	597	PF00069	0.592
MOD_CK1_1	624	630	PF00069	0.703
MOD_CK1_1	649	655	PF00069	0.729
MOD_CK1_1	659	665	PF00069	0.811
MOD_CK1_1	670	676	PF00069	0.701
MOD_CK1_1	681	687	PF00069	0.703
MOD_CK1_1	696	702	PF00069	0.769
MOD_CK1_1	741	747	PF00069	0.803
MOD_CK1_1	858	864	PF00069	0.714
MOD_CK1_1	980	986	PF00069	0.572
MOD_CK2_1	138	144	PF00069	0.832
MOD_CK2_1	50	56	PF00069	0.781
MOD_CK2_1	607	613	PF00069	0.836
MOD_CK2_1	68	74	PF00069	0.730
MOD_CK2_1	715	721	PF00069	0.703
MOD_CK2_1	741	747	PF00069	0.793
MOD_CK2_1	781	787	PF00069	0.636
MOD_CK2_1	972	978	PF00069	0.707
MOD_CK2_1	994	1000	PF00069	0.705
MOD_Cter_Amidation	457	460	PF01082	0.609
MOD_GlcNHglycan	109	112	PF01048	0.605
MOD_GlcNHglycan	146	149	PF01048	0.707
MOD_GlcNHglycan	212	215	PF01048	0.594
MOD_GlcNHglycan	234	238	PF01048	0.712
MOD_GlcNHglycan	26	29	PF01048	0.749
MOD_GlcNHglycan	261	264	PF01048	0.731
MOD_GlcNHglycan	266	269	PF01048	0.763
MOD_GlcNHglycan	319	322	PF01048	0.766
MOD_GlcNHglycan	344	347	PF01048	0.590
MOD_GlcNHglycan	371	374	PF01048	0.587
MOD_GlcNHglycan	40	43	PF01048	0.586
MOD_GlcNHglycan	417	420	PF01048	0.723
MOD_GlcNHglycan	454	457	PF01048	0.712
MOD_GlcNHglycan	467	470	PF01048	0.721
MOD_GlcNHglycan	527	530	PF01048	0.778
MOD_GlcNHglycan	589	593	PF01048	0.729
MOD_GlcNHglycan	658	661	PF01048	0.819
MOD_GlcNHglycan	680	683	PF01048	0.772
MOD_GlcNHglycan	688	691	PF01048	0.582
MOD_GlcNHglycan	696	699	PF01048	0.687
MOD_GlcNHglycan	945	948	PF01048	0.631
MOD_GlcNHglycan	960	963	PF01048	0.766
MOD_GlcNHglycan	974	977	PF01048	0.633
MOD_GSK3_1	103	110	PF00069	0.645
MOD_GSK3_1	135	142	PF00069	0.716
MOD_GSK3_1	151	158	PF00069	0.609
MOD_GSK3_1	338	345	PF00069	0.615
MOD_GSK3_1	368	375	PF00069	0.664
MOD_GSK3_1	38	45	PF00069	0.667
MOD_GSK3_1	408	415	PF00069	0.661
MOD_GSK3_1	440	447	PF00069	0.843
MOD_GSK3_1	461	468	PF00069	0.594
MOD_GSK3_1	481	488	PF00069	0.530
MOD_GSK3_1	500	507	PF00069	0.621
MOD_GSK3_1	542	549	PF00069	0.692
MOD_GSK3_1	587	594	PF00069	0.571
MOD_GSK3_1	607	614	PF00069	0.835
MOD_GSK3_1	642	649	PF00069	0.758
MOD_GSK3_1	662	669	PF00069	0.698
MOD_GSK3_1	681	688	PF00069	0.717
MOD_GSK3_1	781	788	PF00069	0.689
MOD_GSK3_1	855	862	PF00069	0.736
MOD_GSK3_1	916	923	PF00069	0.697
MOD_GSK3_1	934	941	PF00069	0.698
MOD_GSK3_1	964	971	PF00069	0.691
MOD_N-GLC_1	124	129	PF02516	0.763
MOD_N-GLC_1	412	417	PF02516	0.560
MOD_NEK2_1	103	108	PF00069	0.732
MOD_NEK2_1	135	140	PF00069	0.731
MOD_NEK2_1	156	161	PF00069	0.439
MOD_NEK2_1	202	207	PF00069	0.528
MOD_NEK2_1	395	400	PF00069	0.491
MOD_NEK2_1	587	592	PF00069	0.804
MOD_NEK2_1	672	677	PF00069	0.810
MOD_NEK2_1	678	683	PF00069	0.770
MOD_NEK2_1	715	720	PF00069	0.699
MOD_NEK2_1	781	786	PF00069	0.602
MOD_NEK2_1	972	977	PF00069	0.735
MOD_NEK2_2	934	939	PF00069	0.556
MOD_PIKK_1	980	986	PF00454	0.657
MOD_PKA_2	135	141	PF00069	0.700
MOD_PKA_2	284	290	PF00069	0.487
MOD_PKA_2	368	374	PF00069	0.613
MOD_PKA_2	431	437	PF00069	0.588
MOD_PKA_2	452	458	PF00069	0.616
MOD_PKA_2	577	583	PF00069	0.556
MOD_PKA_2	678	684	PF00069	0.698
MOD_PKA_2	741	747	PF00069	0.691
MOD_PKA_2	938	944	PF00069	0.750
MOD_PKA_2	980	986	PF00069	0.639
MOD_PKB_1	290	298	PF00069	0.597
MOD_PKB_1	552	560	PF00069	0.632
MOD_Plk_1	500	506	PF00069	0.773
MOD_Plk_1	612	618	PF00069	0.598
MOD_Plk_1	715	721	PF00069	0.703
MOD_Plk_1	80	86	PF00069	0.793
MOD_Plk_1	994	1000	PF00069	0.626
MOD_Plk_4	156	162	PF00069	0.583
MOD_Plk_4	16	22	PF00069	0.695
MOD_Plk_4	395	401	PF00069	0.504
MOD_Plk_4	500	506	PF00069	0.699
MOD_Plk_4	577	583	PF00069	0.630
MOD_Plk_4	646	652	PF00069	0.802
MOD_Plk_4	715	721	PF00069	0.732
MOD_Plk_4	917	923	PF00069	0.697
MOD_Plk_4	994	1000	PF00069	0.603
MOD_ProDKin_1	142	148	PF00069	0.672
MOD_ProDKin_1	151	157	PF00069	0.571
MOD_ProDKin_1	22	28	PF00069	0.771
MOD_ProDKin_1	267	273	PF00069	0.759
MOD_ProDKin_1	45	51	PF00069	0.725
MOD_ProDKin_1	470	476	PF00069	0.682
MOD_ProDKin_1	642	648	PF00069	0.766
MOD_ProDKin_1	659	665	PF00069	0.676
MOD_ProDKin_1	667	673	PF00069	0.607
MOD_ProDKin_1	68	74	PF00069	0.798
MOD_ProDKin_1	683	689	PF00069	0.563
MOD_ProDKin_1	808	814	PF00069	0.772
MOD_ProDKin_1	832	838	PF00069	0.688
MOD_ProDKin_1	847	853	PF00069	0.728
MOD_ProDKin_1	89	95	PF00069	0.661
MOD_ProDKin_1	899	905	PF00069	0.640
MOD_ProDKin_1	964	970	PF00069	0.768
TRG_DiLeu_BaEn_1	173	178	PF01217	0.675
TRG_DiLeu_BaLyEn_6	335	340	PF01217	0.726
TRG_ENDOCYTIC_2	1012	1015	PF00928	0.584
TRG_ENDOCYTIC_2	1020	1023	PF00928	0.585
TRG_ENDOCYTIC_2	726	729	PF00928	0.549
TRG_ER_diArg_1	1039	1041	PF00400	0.706
TRG_ER_diArg_1	280	283	PF00400	0.660
TRG_ER_diArg_1	289	292	PF00400	0.564
TRG_ER_diArg_1	35	37	PF00400	0.667
TRG_ER_diArg_1	437	439	PF00400	0.596
TRG_ER_diArg_1	459	461	PF00400	0.601
TRG_ER_diArg_1	505	508	PF00400	0.582
TRG_ER_diArg_1	552	555	PF00400	0.794
TRG_ER_diArg_1	729	732	PF00400	0.737
TRG_ER_diArg_1	897	900	PF00400	0.721

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1ILA0	Leptomonas seymouri	31%	100%
A0A3S7X4K1	Leishmania donovani	87%	100%
A4HJC9	Leishmania braziliensis	65%	100%
A4I6S5	Leishmania infantum	87%	100%
E9B1U7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	99%