Putative transcription like protein nupm1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

transcription like protein nupm1, putative

Species:

Leishmania major

UniProt:

Q4Q668_LEIMA

TriTrypDb:

LmjF.31.1940 , LMJLV39_310027700 , LMJSD75_310027700

Length:

485

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	3
GO:0110165	cellular anatomical entity	1	3

Expansion

Sequence features

Q4Q668

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q668

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	105	107	PF00675	0.462
CLV_NRD_NRD_1	112	114	PF00675	0.473
CLV_NRD_NRD_1	118	120	PF00675	0.442
CLV_NRD_NRD_1	200	202	PF00675	0.616
CLV_NRD_NRD_1	241	243	PF00675	0.445
CLV_NRD_NRD_1	417	419	PF00675	0.565
CLV_NRD_NRD_1	48	50	PF00675	0.496
CLV_PCSK_FUR_1	238	242	PF00082	0.474
CLV_PCSK_FUR_1	418	422	PF00082	0.531
CLV_PCSK_KEX2_1	103	105	PF00082	0.462
CLV_PCSK_KEX2_1	111	113	PF00082	0.481
CLV_PCSK_KEX2_1	118	120	PF00082	0.433
CLV_PCSK_KEX2_1	200	202	PF00082	0.616
CLV_PCSK_KEX2_1	240	242	PF00082	0.477
CLV_PCSK_KEX2_1	417	419	PF00082	0.570
CLV_PCSK_KEX2_1	420	422	PF00082	0.560
CLV_PCSK_KEX2_1	48	50	PF00082	0.496
CLV_PCSK_PC1ET2_1	103	105	PF00082	0.462
CLV_PCSK_PC1ET2_1	420	422	PF00082	0.536
CLV_PCSK_PC7_1	108	114	PF00082	0.392
CLV_PCSK_SKI1_1	282	286	PF00082	0.606
CLV_Separin_Metazoa	92	96	PF03568	0.667
DEG_Kelch_Keap1_1	62	67	PF01344	0.823
DEG_SCF_FBW7_2	85	92	PF00400	0.681
DEG_SPOP_SBC_1	166	170	PF00917	0.760
DEG_SPOP_SBC_1	374	378	PF00917	0.660
DOC_AGCK_PIF_1	251	256	PF00069	0.546
DOC_CYCLIN_yCln2_LP_2	478	484	PF00134	0.748
DOC_PP2B_LxvP_1	180	183	PF13499	0.730
DOC_PP2B_LxvP_1	36	39	PF13499	0.663
DOC_PP2B_LxvP_1	465	468	PF13499	0.752
DOC_USP7_MATH_1	148	152	PF00917	0.838
DOC_USP7_MATH_1	296	300	PF00917	0.767
DOC_USP7_MATH_1	362	366	PF00917	0.839
DOC_USP7_MATH_1	374	378	PF00917	0.732
DOC_USP7_MATH_1	450	454	PF00917	0.753
DOC_USP7_MATH_1	461	465	PF00917	0.715
DOC_USP7_MATH_1	79	83	PF00917	0.710
DOC_USP7_UBL2_3	420	424	PF12436	0.753
DOC_USP7_UBL2_3	97	101	PF12436	0.632
DOC_WW_Pin1_4	383	388	PF00397	0.831
DOC_WW_Pin1_4	85	90	PF00397	0.685
LIG_14-3-3_CanoR_1	129	134	PF00244	0.605
LIG_14-3-3_CanoR_1	167	173	PF00244	0.748
LIG_14-3-3_CanoR_1	176	180	PF00244	0.668
LIG_14-3-3_CanoR_1	216	224	PF00244	0.667
LIG_14-3-3_CanoR_1	309	314	PF00244	0.775
LIG_14-3-3_CanoR_1	418	424	PF00244	0.826
LIG_BRCT_BRCA1_1	330	334	PF00533	0.739
LIG_BRCT_BRCA1_1	432	436	PF00533	0.736
LIG_Clathr_ClatBox_1	335	339	PF01394	0.734
LIG_FHA_1	167	173	PF00498	0.757
LIG_FHA_1	186	192	PF00498	0.622
LIG_FHA_1	308	314	PF00498	0.802
LIG_FHA_2	325	331	PF00498	0.717
LIG_FHA_2	420	426	PF00498	0.723
LIG_LIR_Apic_2	177	182	PF02991	0.825
LIG_LIR_Gen_1	255	260	PF02991	0.598
LIG_LIR_Nem_3	330	335	PF02991	0.813
LIG_LIR_Nem_3	422	426	PF02991	0.723
LIG_LIR_Nem_3	72	78	PF02991	0.773
LIG_LYPXL_yS_3	332	335	PF13949	0.813
LIG_MLH1_MIPbox_1	432	436	PF16413	0.736
LIG_MYND_1	85	89	PF01753	0.684
LIG_PCNA_yPIPBox_3	424	436	PF02747	0.729
LIG_Pex14_2	21	25	PF04695	0.405
LIG_Pex14_2	371	375	PF04695	0.651
LIG_SH2_STAP1	256	260	PF00017	0.657
LIG_SH2_STAT5	179	182	PF00017	0.755
LIG_SH2_STAT5	230	233	PF00017	0.641
LIG_SH2_STAT5	32	35	PF00017	0.643
LIG_SH3_3	465	471	PF00018	0.768
LIG_TRAF2_1	107	110	PF00917	0.665
LIG_TRAF2_1	114	117	PF00917	0.669
LIG_TRAF2_1	467	470	PF00917	0.674
LIG_TRAF2_1	89	92	PF00917	0.677
LIG_WW_3	83	87	PF00397	0.624
MOD_CK1_1	151	157	PF00069	0.719
MOD_CK1_1	161	167	PF00069	0.727
MOD_CK1_1	202	208	PF00069	0.704
MOD_CK1_1	211	217	PF00069	0.683
MOD_CK1_1	220	226	PF00069	0.564
MOD_CK1_1	263	269	PF00069	0.675
MOD_CK1_1	273	279	PF00069	0.729
MOD_CK1_1	307	313	PF00069	0.705
MOD_CK1_1	358	364	PF00069	0.675
MOD_CK1_1	378	384	PF00069	0.720
MOD_CK1_1	446	452	PF00069	0.814
MOD_CK1_1	62	68	PF00069	0.798
MOD_CK2_1	129	135	PF00069	0.623
MOD_CK2_1	140	146	PF00069	0.746
MOD_CK2_1	258	264	PF00069	0.576
MOD_CK2_1	324	330	PF00069	0.653
MOD_CK2_1	463	469	PF00069	0.630
MOD_CK2_1	61	67	PF00069	0.717
MOD_GlcNHglycan	14	17	PF01048	0.439
MOD_GlcNHglycan	160	163	PF01048	0.721
MOD_GlcNHglycan	183	186	PF01048	0.703
MOD_GlcNHglycan	204	207	PF01048	0.729
MOD_GlcNHglycan	213	216	PF01048	0.603
MOD_GlcNHglycan	272	275	PF01048	0.718
MOD_GlcNHglycan	281	285	PF01048	0.643
MOD_GlcNHglycan	3	6	PF01048	0.539
MOD_GlcNHglycan	306	309	PF01048	0.697
MOD_GlcNHglycan	315	318	PF01048	0.692
MOD_GlcNHglycan	357	360	PF01048	0.687
MOD_GlcNHglycan	390	393	PF01048	0.711
MOD_GlcNHglycan	402	405	PF01048	0.681
MOD_GlcNHglycan	432	435	PF01048	0.647
MOD_GlcNHglycan	465	468	PF01048	0.759
MOD_GlcNHglycan	64	67	PF01048	0.654
MOD_GSK3_1	148	155	PF00069	0.717
MOD_GSK3_1	157	164	PF00069	0.729
MOD_GSK3_1	181	188	PF00069	0.648
MOD_GSK3_1	207	214	PF00069	0.700
MOD_GSK3_1	259	266	PF00069	0.630
MOD_GSK3_1	268	275	PF00069	0.710
MOD_GSK3_1	292	299	PF00069	0.671
MOD_GSK3_1	309	316	PF00069	0.692
MOD_GSK3_1	324	331	PF00069	0.579
MOD_GSK3_1	347	354	PF00069	0.718
MOD_GSK3_1	358	365	PF00069	0.618
MOD_GSK3_1	374	381	PF00069	0.770
MOD_GSK3_1	446	453	PF00069	0.754
MOD_N-GLC_1	362	367	PF02516	0.690
MOD_N-GLC_1	436	441	PF02516	0.604
MOD_NEK2_1	1	6	PF00069	0.575
MOD_NEK2_1	265	270	PF00069	0.707
MOD_NEK2_1	355	360	PF00069	0.647
MOD_NEK2_1	375	380	PF00069	0.717
MOD_NEK2_1	435	440	PF00069	0.553
MOD_NEK2_1	60	65	PF00069	0.803
MOD_NEK2_2	162	167	PF00069	0.679
MOD_NEK2_2	185	190	PF00069	0.650
MOD_OFUCOSY	297	302	PF10250	0.577
MOD_PIKK_1	117	123	PF00454	0.591
MOD_PIKK_1	152	158	PF00454	0.578
MOD_PIKK_1	217	223	PF00454	0.672
MOD_PIKK_1	273	279	PF00454	0.825
MOD_PIKK_1	347	353	PF00454	0.692
MOD_PK_1	129	135	PF00069	0.498
MOD_PK_1	309	315	PF00069	0.732
MOD_PKA_1	200	206	PF00069	0.699
MOD_PKA_2	117	123	PF00069	0.591
MOD_PKA_2	166	172	PF00069	0.703
MOD_PKA_2	175	181	PF00069	0.587
MOD_PKA_2	199	205	PF00069	0.814
MOD_PKA_2	208	214	PF00069	0.575
MOD_PKA_2	217	223	PF00069	0.589
MOD_PKA_2	351	357	PF00069	0.626
MOD_PKB_1	290	298	PF00069	0.754
MOD_Plk_1	185	191	PF00069	0.650
MOD_Plk_1	472	478	PF00069	0.677
MOD_Plk_4	175	181	PF00069	0.824
MOD_Plk_4	226	232	PF00069	0.557
MOD_Plk_4	366	372	PF00069	0.559
MOD_ProDKin_1	383	389	PF00069	0.810
MOD_ProDKin_1	85	91	PF00069	0.602
TRG_DiLeu_BaEn_2	329	335	PF01217	0.647
TRG_DiLeu_BaEn_4	243	249	PF01217	0.566
TRG_ENDOCYTIC_2	256	259	PF00928	0.566
TRG_ENDOCYTIC_2	332	335	PF00928	0.682
TRG_ER_diArg_1	104	106	PF00400	0.592
TRG_ER_diArg_1	111	113	PF00400	0.502
TRG_ER_diArg_1	231	234	PF00400	0.528
TRG_ER_diArg_1	238	241	PF00400	0.531
TRG_ER_diArg_1	416	418	PF00400	0.717
TRG_ER_diArg_1	48	50	PF00400	0.615
TRG_NLS_MonoCore_2	102	107	PF00514	0.539
TRG_NLS_MonoExtN_4	101	107	PF00514	0.571
TRG_Pf-PMV_PEXEL_1	319	323	PF00026	0.701
TRG_Pf-PMV_PEXEL_1	49	53	PF00026	0.587

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IGX0	Leptomonas seymouri	42%	99%
A0A3Q8IGF6	Leishmania donovani	89%	100%
A4HJH6	Leishmania braziliensis	59%	100%
A4HJX3	Leishmania braziliensis	59%	100%
A4I6W9	Leishmania infantum	89%	100%
E9B1Z3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	100%