Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q663_LEIMA

TriTrypDb:

LmjF.31.1990 , LMJLV39_310028300 , LMJSD75_310028300 , LMJSD75_310028400

Length:

709

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q663

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q663

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	225	229	PF00656	0.617
CLV_C14_Caspase3-7	307	311	PF00656	0.607
CLV_C14_Caspase3-7	565	569	PF00656	0.613
CLV_NRD_NRD_1	108	110	PF00675	0.637
CLV_NRD_NRD_1	11	13	PF00675	0.629
CLV_NRD_NRD_1	192	194	PF00675	0.628
CLV_NRD_NRD_1	207	209	PF00675	0.549
CLV_NRD_NRD_1	343	345	PF00675	0.641
CLV_NRD_NRD_1	394	396	PF00675	0.604
CLV_NRD_NRD_1	55	57	PF00675	0.586
CLV_NRD_NRD_1	604	606	PF00675	0.540
CLV_NRD_NRD_1	683	685	PF00675	0.559
CLV_NRD_NRD_1	706	708	PF00675	0.531
CLV_PCSK_KEX2_1	108	110	PF00082	0.637
CLV_PCSK_KEX2_1	11	13	PF00082	0.629
CLV_PCSK_KEX2_1	192	194	PF00082	0.628
CLV_PCSK_KEX2_1	207	209	PF00082	0.549
CLV_PCSK_KEX2_1	343	345	PF00082	0.641
CLV_PCSK_KEX2_1	394	396	PF00082	0.604
CLV_PCSK_KEX2_1	55	57	PF00082	0.586
CLV_PCSK_KEX2_1	603	605	PF00082	0.544
CLV_PCSK_KEX2_1	682	684	PF00082	0.553
CLV_PCSK_KEX2_1	706	708	PF00082	0.531
CLV_PCSK_PC7_1	104	110	PF00082	0.612
CLV_PCSK_SKI1_1	207	211	PF00082	0.594
CLV_PCSK_SKI1_1	395	399	PF00082	0.557
CLV_Separin_Metazoa	679	683	PF03568	0.534
DEG_SCF_FBW7_1	178	183	PF00400	0.589
DOC_CDC14_PxL_1	662	670	PF14671	0.544
DOC_CKS1_1	452	457	PF01111	0.625
DOC_CKS1_1	694	699	PF01111	0.757
DOC_CYCLIN_RxL_1	205	216	PF00134	0.626
DOC_CYCLIN_yCln2_LP_2	250	253	PF00134	0.586
DOC_MAPK_gen_1	32	42	PF00069	0.537
DOC_MAPK_MEF2A_6	406	414	PF00069	0.609
DOC_PP2B_LxvP_1	250	253	PF13499	0.626
DOC_PP2B_LxvP_1	362	365	PF13499	0.629
DOC_PP2B_LxvP_1	509	512	PF13499	0.590
DOC_PP2B_LxvP_1	618	621	PF13499	0.564
DOC_USP7_MATH_1	202	206	PF00917	0.579
DOC_USP7_MATH_1	302	306	PF00917	0.611
DOC_USP7_MATH_1	320	324	PF00917	0.694
DOC_USP7_MATH_1	418	422	PF00917	0.658
DOC_USP7_MATH_1	498	502	PF00917	0.579
DOC_USP7_MATH_1	553	557	PF00917	0.606
DOC_USP7_MATH_1	572	576	PF00917	0.538
DOC_USP7_MATH_1	675	679	PF00917	0.545
DOC_USP7_MATH_2	474	480	PF00917	0.569
DOC_WW_Pin1_4	107	112	PF00397	0.643
DOC_WW_Pin1_4	123	128	PF00397	0.518
DOC_WW_Pin1_4	157	162	PF00397	0.618
DOC_WW_Pin1_4	176	181	PF00397	0.712
DOC_WW_Pin1_4	182	187	PF00397	0.746
DOC_WW_Pin1_4	210	215	PF00397	0.620
DOC_WW_Pin1_4	241	246	PF00397	0.592
DOC_WW_Pin1_4	254	259	PF00397	0.747
DOC_WW_Pin1_4	336	341	PF00397	0.623
DOC_WW_Pin1_4	44	49	PF00397	0.556
DOC_WW_Pin1_4	451	456	PF00397	0.798
DOC_WW_Pin1_4	689	694	PF00397	0.731
LIG_14-3-3_CanoR_1	109	115	PF00244	0.638
LIG_14-3-3_CanoR_1	138	145	PF00244	0.618
LIG_14-3-3_CanoR_1	192	202	PF00244	0.576
LIG_14-3-3_CanoR_1	207	213	PF00244	0.531
LIG_14-3-3_CanoR_1	281	287	PF00244	0.680
LIG_14-3-3_CanoR_1	324	329	PF00244	0.623
LIG_14-3-3_CanoR_1	480	485	PF00244	0.585
LIG_14-3-3_CanoR_1	507	512	PF00244	0.547
LIG_14-3-3_CanoR_1	55	65	PF00244	0.629
LIG_14-3-3_CanoR_1	557	564	PF00244	0.607
LIG_14-3-3_CanoR_1	634	638	PF00244	0.618
LIG_14-3-3_CanoR_1	682	691	PF00244	0.572
LIG_BIR_II_1	1	5	PF00653	0.628
LIG_BRCT_BRCA1_1	231	235	PF00533	0.576
LIG_BRCT_BRCA1_2	231	237	PF00533	0.564
LIG_FHA_1	246	252	PF00498	0.577
LIG_FHA_1	328	334	PF00498	0.619
LIG_FHA_1	457	463	PF00498	0.777
LIG_FHA_1	464	470	PF00498	0.736
LIG_FHA_2	166	172	PF00498	0.656
LIG_FHA_2	290	296	PF00498	0.601
LIG_FHA_2	346	352	PF00498	0.615
LIG_FHA_2	421	427	PF00498	0.562
LIG_FHA_2	563	569	PF00498	0.625
LIG_Integrin_RGD_1	226	228	PF01839	0.579
LIG_LIR_Apic_2	247	252	PF02991	0.618
LIG_LIR_Gen_1	272	280	PF02991	0.605
LIG_LIR_Gen_1	37	46	PF02991	0.541
LIG_LIR_Gen_1	476	486	PF02991	0.565
LIG_LIR_Nem_3	188	194	PF02991	0.730
LIG_LIR_Nem_3	242	246	PF02991	0.721
LIG_LIR_Nem_3	272	276	PF02991	0.607
LIG_LIR_Nem_3	37	42	PF02991	0.538
LIG_LIR_Nem_3	430	436	PF02991	0.606
LIG_LIR_Nem_3	476	481	PF02991	0.560
LIG_LIR_Nem_3	612	618	PF02991	0.613
LIG_LYPXL_yS_3	14	17	PF13949	0.576
LIG_NRBOX	385	391	PF00104	0.768
LIG_NRP_CendR_1	706	709	PF00754	0.531
LIG_PCNA_yPIPBox_3	383	395	PF02747	0.594
LIG_PTB_Apo_2	581	588	PF02174	0.579
LIG_PTB_Phospho_1	581	587	PF10480	0.581
LIG_RPA_C_Fungi	188	200	PF08784	0.583
LIG_SH2_CRK	452	456	PF00017	0.629
LIG_SH2_CRK	478	482	PF00017	0.567
LIG_SH2_GRB2like	436	439	PF00017	0.615
LIG_SH2_STAP1	478	482	PF00017	0.567
LIG_SH2_STAP1	616	620	PF00017	0.702
LIG_SH2_STAT5	249	252	PF00017	0.621
LIG_SH2_STAT5	436	439	PF00017	0.615
LIG_SH3_1	260	266	PF00018	0.647
LIG_SH3_3	121	127	PF00018	0.632
LIG_SH3_3	175	181	PF00018	0.836
LIG_SH3_3	255	261	PF00018	0.642
LIG_SH3_3	272	278	PF00018	0.501
LIG_SH3_3	459	465	PF00018	0.572
LIG_SH3_3	479	485	PF00018	0.569
LIG_SH3_3	489	495	PF00018	0.514
LIG_SUMO_SIM_anti_2	369	375	PF11976	0.609
LIG_SUMO_SIM_par_1	208	213	PF11976	0.632
LIG_TRFH_1	249	253	PF08558	0.583
LIG_WRC_WIRS_1	152	157	PF05994	0.632
LIG_WW_3	179	183	PF00397	0.597
LIG_WW_3	262	266	PF00397	0.645
MOD_CDC14_SPxK_1	257	260	PF00782	0.617
MOD_CDK_SPK_2	123	128	PF00069	0.616
MOD_CDK_SPxK_1	176	182	PF00069	0.599
MOD_CDK_SPxK_1	254	260	PF00069	0.620
MOD_CDK_SPxxK_3	336	343	PF00069	0.626
MOD_CK1_1	110	116	PF00069	0.633
MOD_CK1_1	154	160	PF00069	0.678
MOD_CK1_1	185	191	PF00069	0.605
MOD_CK1_1	213	219	PF00069	0.797
MOD_CK1_1	236	242	PF00069	0.799
MOD_CK1_1	254	260	PF00069	0.687
MOD_CK1_1	289	295	PF00069	0.813
MOD_CK1_1	327	333	PF00069	0.615
MOD_CK1_1	336	342	PF00069	0.586
MOD_CK1_1	47	53	PF00069	0.627
MOD_CK1_1	501	507	PF00069	0.643
MOD_CK1_1	538	544	PF00069	0.561
MOD_CK1_1	555	561	PF00069	0.577
MOD_CK1_1	58	64	PF00069	0.559
MOD_CK1_1	614	620	PF00069	0.795
MOD_CK1_1	633	639	PF00069	0.485
MOD_CK1_1	692	698	PF00069	0.745
MOD_CK1_1	77	83	PF00069	0.577
MOD_CK1_1	84	90	PF00069	0.603
MOD_CK2_1	289	295	PF00069	0.600
MOD_CK2_1	329	335	PF00069	0.619
MOD_CK2_1	345	351	PF00069	0.548
MOD_CK2_1	420	426	PF00069	0.566
MOD_CK2_1	428	434	PF00069	0.530
MOD_CK2_1	546	552	PF00069	0.578
MOD_CK2_1	574	580	PF00069	0.698
MOD_DYRK1A_RPxSP_1	182	186	PF00069	0.596
MOD_GlcNHglycan	120	123	PF01048	0.686
MOD_GlcNHglycan	156	159	PF01048	0.722
MOD_GlcNHglycan	182	185	PF01048	0.626
MOD_GlcNHglycan	187	190	PF01048	0.591
MOD_GlcNHglycan	204	207	PF01048	0.637
MOD_GlcNHglycan	231	234	PF01048	0.593
MOD_GlcNHglycan	238	241	PF01048	0.510
MOD_GlcNHglycan	313	316	PF01048	0.702
MOD_GlcNHglycan	335	338	PF01048	0.716
MOD_GlcNHglycan	441	444	PF01048	0.627
MOD_GlcNHglycan	500	503	PF01048	0.728
MOD_GlcNHglycan	529	532	PF01048	0.623
MOD_GlcNHglycan	543	546	PF01048	0.722
MOD_GlcNHglycan	548	551	PF01048	0.756
MOD_GlcNHglycan	685	688	PF01048	0.606
MOD_GlcNHglycan	76	79	PF01048	0.595
MOD_GlcNHglycan	83	86	PF01048	0.596
MOD_GSK3_1	140	147	PF00069	0.591
MOD_GSK3_1	172	179	PF00069	0.741
MOD_GSK3_1	229	236	PF00069	0.782
MOD_GSK3_1	241	248	PF00069	0.554
MOD_GSK3_1	286	293	PF00069	0.633
MOD_GSK3_1	320	327	PF00069	0.649
MOD_GSK3_1	329	336	PF00069	0.627
MOD_GSK3_1	434	441	PF00069	0.594
MOD_GSK3_1	451	458	PF00069	0.812
MOD_GSK3_1	47	54	PF00069	0.623
MOD_GSK3_1	476	483	PF00069	0.583
MOD_GSK3_1	501	508	PF00069	0.657
MOD_GSK3_1	511	518	PF00069	0.561
MOD_GSK3_1	551	558	PF00069	0.669
MOD_GSK3_1	619	626	PF00069	0.673
MOD_GSK3_1	685	692	PF00069	0.612
MOD_GSK3_1	70	77	PF00069	0.591
MOD_LATS_1	116	122	PF00433	0.635
MOD_LATS_1	53	59	PF00433	0.621
MOD_N-GLC_1	194	199	PF02516	0.614
MOD_N-GLC_1	4	9	PF02516	0.613
MOD_N-GLC_1	469	474	PF02516	0.577
MOD_N-GLC_1	526	531	PF02516	0.549
MOD_NEK2_1	140	145	PF00069	0.614
MOD_NEK2_1	151	156	PF00069	0.558
MOD_NEK2_1	328	333	PF00069	0.579
MOD_NEK2_1	456	461	PF00069	0.617
MOD_NEK2_1	49	54	PF00069	0.583
MOD_NEK2_1	505	510	PF00069	0.571
MOD_NEK2_1	535	540	PF00069	0.587
MOD_PIKK_1	140	146	PF00454	0.609
MOD_PIKK_1	4	10	PF00454	0.613
MOD_PIKK_1	557	563	PF00454	0.614
MOD_PIKK_1	623	629	PF00454	0.619
MOD_PK_1	265	271	PF00069	0.631
MOD_PK_1	507	513	PF00069	0.550
MOD_PKA_1	55	61	PF00069	0.576
MOD_PKA_1	683	689	PF00069	0.573
MOD_PKA_2	280	286	PF00069	0.673
MOD_PKA_2	311	317	PF00069	0.644
MOD_PKA_2	515	521	PF00069	0.576
MOD_PKA_2	527	533	PF00069	0.464
MOD_PKA_2	538	544	PF00069	0.508
MOD_PKA_2	55	61	PF00069	0.576
MOD_PKA_2	556	562	PF00069	0.543
MOD_PKA_2	633	639	PF00069	0.618
MOD_PKA_2	683	689	PF00069	0.573
MOD_Plk_1	116	122	PF00069	0.642
MOD_Plk_1	296	302	PF00069	0.642
MOD_Plk_1	611	617	PF00069	0.584
MOD_Plk_2-3	428	434	PF00069	0.562
MOD_Plk_2-3	463	469	PF00069	0.603
MOD_Plk_4	151	157	PF00069	0.632
MOD_Plk_4	245	251	PF00069	0.629
MOD_Plk_4	501	507	PF00069	0.662
MOD_Plk_4	611	617	PF00069	0.584
MOD_ProDKin_1	107	113	PF00069	0.643
MOD_ProDKin_1	123	129	PF00069	0.514
MOD_ProDKin_1	157	163	PF00069	0.621
MOD_ProDKin_1	176	182	PF00069	0.714
MOD_ProDKin_1	210	216	PF00069	0.618
MOD_ProDKin_1	241	247	PF00069	0.594
MOD_ProDKin_1	254	260	PF00069	0.748
MOD_ProDKin_1	336	342	PF00069	0.624
MOD_ProDKin_1	44	50	PF00069	0.557
MOD_ProDKin_1	451	457	PF00069	0.795
MOD_ProDKin_1	689	695	PF00069	0.729
MOD_SUMO_rev_2	590	596	PF00179	0.562
TRG_DiLeu_BaEn_1	369	374	PF01217	0.607
TRG_DiLeu_BaEn_1	385	390	PF01217	0.494
TRG_DiLeu_BaLyEn_6	205	210	PF01217	0.595
TRG_DiLeu_LyEn_5	385	390	PF01217	0.592
TRG_ENDOCYTIC_2	14	17	PF00928	0.576
TRG_ENDOCYTIC_2	273	276	PF00928	0.603
TRG_ENDOCYTIC_2	478	481	PF00928	0.569
TRG_ENDOCYTIC_2	615	618	PF00928	0.618
TRG_ER_diArg_1	191	193	PF00400	0.631
TRG_ER_diArg_1	207	209	PF00400	0.543
TRG_ER_diArg_1	360	363	PF00400	0.601
TRG_ER_diArg_1	393	395	PF00400	0.607
TRG_ER_diArg_1	55	57	PF00400	0.586
TRG_ER_diArg_1	603	605	PF00400	0.544
TRG_ER_diArg_1	681	684	PF00400	0.549
TRG_ER_diArg_1	706	709	PF00400	0.601
TRG_Pf-PMV_PEXEL_1	395	400	PF00026	0.589

Homologs


Protein	Taxonomy	Sequence identity	Coverage
E9B1Z8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	73%	100%