LeishMANIAdb
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Leishmanolysin

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Leishmanolysin
Gene product:
GP63-like protein, leishmanolysin-like protein
Species:
Leishmania major
UniProt:
Q4Q662_LEIMA
TriTrypDb:
LmjF.31.2000 , LMJLV39_310028700 * , LMJSD75_310028800 *
Length:
636

Annotations

LeishMANIAdb annotations

Publication identifier(s): 31356625
GPI-anchored cell surface protease. Broad-spectrum ectoenzyme involved in pathogenesis. Heavily expanded family in all parazitic species.. Localization: Cell surface (experimental)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 2
Forrest at al. (procyclic) no yes: 2
Silverman et al. no yes: 0
Pissara et al. yes yes: 69
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 5
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 62, no: 10
NetGPI no yes: 0, no: 72
Cellular components
Term Name Level Count
GO:0005737 cytoplasm 2 7
GO:0016020 membrane 2 73
GO:0110165 cellular anatomical entity 1 73
GO:0018995 host cellular component 2 4
GO:0033643 host cell part 3 4
GO:0033646 host intracellular part 4 4
GO:0033647 host intracellular organelle 5 4
GO:0033648 host intracellular membrane-bounded organelle 6 4
GO:0042025 host cell nucleus 7 4

Expansion

Sequence features

Q4Q662
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q662

Function

Biological processes
Term Name Level Count
GO:0006508 proteolysis 4 73
GO:0006807 nitrogen compound metabolic process 2 73
GO:0007155 cell adhesion 2 73
GO:0008152 metabolic process 1 73
GO:0009987 cellular process 1 73
GO:0019538 protein metabolic process 3 73
GO:0043170 macromolecule metabolic process 3 73
GO:0044238 primary metabolic process 2 73
GO:0071704 organic substance metabolic process 2 73
GO:1901564 organonitrogen compound metabolic process 3 73
GO:0009966 regulation of signal transduction 4 4
GO:0010646 regulation of cell communication 4 4
GO:0010749 regulation of nitric oxide mediated signal transduction 6 4
GO:0023051 regulation of signaling 3 4
GO:0035821 modulation of process of another organism 2 4
GO:0044003 modulation by symbiont of host process 3 4
GO:0044068 modulation by symbiont of host cellular process 4 4
GO:0044081 modulation by symbiont of host nitric oxide-mediated signal transduction 5 4
GO:0044403 biological process involved in symbiotic interaction 2 4
GO:0044419 biological process involved in interspecies interaction between organisms 1 4
GO:0044501 modulation of signal transduction in another organism 3 4
GO:0048583 regulation of response to stimulus 3 4
GO:0050789 regulation of biological process 2 4
GO:0050794 regulation of cellular process 3 4
GO:0051701 biological process involved in interaction with host 3 4
GO:0052027 modulation by symbiont of host signal transduction pathway 4 4
GO:0065007 biological regulation 1 4
GO:0075130 modulation by symbiont of host protein kinase-mediated signal transduction 5 4
GO:1902531 regulation of intracellular signal transduction 5 4
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 73
GO:0004175 endopeptidase activity 4 73
GO:0004222 metalloendopeptidase activity 5 73
GO:0005488 binding 1 73
GO:0008233 peptidase activity 3 73
GO:0008237 metallopeptidase activity 4 73
GO:0016787 hydrolase activity 2 73
GO:0043167 ion binding 2 73
GO:0043169 cation binding 3 73
GO:0046872 metal ion binding 4 73
GO:0140096 catalytic activity, acting on a protein 2 73
GO:0008047 enzyme activator activity 3 4
GO:0008160 protein tyrosine phosphatase activator activity 6 4
GO:0019208 phosphatase regulator activity 3 4
GO:0019211 phosphatase activator activity 4 4
GO:0019888 protein phosphatase regulator activity 4 4
GO:0030234 enzyme regulator activity 2 4
GO:0072542 protein phosphatase activator activity 5 4
GO:0098772 molecular function regulator activity 1 4
GO:0140677 molecular function activator activity 2 4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 168 170 PF00675 0.400
CLV_NRD_NRD_1 278 280 PF00675 0.547
CLV_NRD_NRD_1 358 360 PF00675 0.446
CLV_PCSK_FUR_1 276 280 PF00082 0.525
CLV_PCSK_FUR_1 309 313 PF00082 0.535
CLV_PCSK_KEX2_1 168 170 PF00082 0.544
CLV_PCSK_KEX2_1 278 280 PF00082 0.547
CLV_PCSK_KEX2_1 311 313 PF00082 0.484
CLV_PCSK_KEX2_1 357 359 PF00082 0.444
CLV_PCSK_PC1ET2_1 311 313 PF00082 0.527
CLV_PCSK_PC1ET2_1 357 359 PF00082 0.466
CLV_PCSK_PC7_1 164 170 PF00082 0.400
CLV_PCSK_SKI1_1 146 150 PF00082 0.521
CLV_PCSK_SKI1_1 299 303 PF00082 0.477
CLV_PCSK_SKI1_1 359 363 PF00082 0.491
CLV_PCSK_SKI1_1 408 412 PF00082 0.484
CLV_PCSK_SKI1_1 446 450 PF00082 0.502
DEG_SPOP_SBC_1 171 175 PF00917 0.200
DEG_SPOP_SBC_1 600 604 PF00917 0.514
DOC_CDC14_PxL_1 302 310 PF14671 0.294
DOC_MAPK_gen_1 309 316 PF00069 0.288
DOC_PP1_RVXF_1 388 394 PF00149 0.364
DOC_PP2B_LxvP_1 365 368 PF13499 0.388
DOC_PP4_FxxP_1 189 192 PF00568 0.308
DOC_PP4_FxxP_1 410 413 PF00568 0.205
DOC_PP4_FxxP_1 521 524 PF00568 0.203
DOC_USP7_MATH_1 125 129 PF00917 0.265
DOC_USP7_MATH_1 133 137 PF00917 0.242
DOC_USP7_MATH_1 170 174 PF00917 0.352
DOC_USP7_MATH_1 270 274 PF00917 0.347
DOC_USP7_MATH_1 28 32 PF00917 0.489
DOC_USP7_MATH_1 349 353 PF00917 0.309
DOC_USP7_MATH_1 455 459 PF00917 0.257
DOC_USP7_MATH_1 564 568 PF00917 0.294
DOC_USP7_MATH_1 601 605 PF00917 0.466
DOC_USP7_MATH_1 607 611 PF00917 0.454
DOC_USP7_UBL2_3 530 534 PF12436 0.354
DOC_WW_Pin1_4 213 218 PF00397 0.274
DOC_WW_Pin1_4 419 424 PF00397 0.325
DOC_WW_Pin1_4 565 570 PF00397 0.343
DOC_WW_Pin1_4 605 610 PF00397 0.550
LIG_14-3-3_CanoR_1 169 178 PF00244 0.255
LIG_14-3-3_CanoR_1 278 286 PF00244 0.240
LIG_14-3-3_CanoR_1 374 379 PF00244 0.305
LIG_14-3-3_CanoR_1 435 444 PF00244 0.296
LIG_14-3-3_CanoR_1 446 456 PF00244 0.321
LIG_BIR_II_1 1 5 PF00653 0.567
LIG_BRCT_BRCA1_1 292 296 PF00533 0.393
LIG_deltaCOP1_diTrp_1 12 19 PF00928 0.440
LIG_FHA_1 145 151 PF00498 0.296
LIG_FHA_1 172 178 PF00498 0.309
LIG_FHA_1 195 201 PF00498 0.278
LIG_FHA_1 231 237 PF00498 0.396
LIG_FHA_1 272 278 PF00498 0.411
LIG_FHA_1 290 296 PF00498 0.336
LIG_FHA_1 420 426 PF00498 0.327
LIG_FHA_1 537 543 PF00498 0.387
LIG_FHA_1 84 90 PF00498 0.290
LIG_LIR_Apic_2 188 192 PF02991 0.315
LIG_LIR_Apic_2 520 524 PF02991 0.198
LIG_LIR_Apic_2 585 591 PF02991 0.290
LIG_LIR_Gen_1 537 547 PF02991 0.342
LIG_LIR_Nem_3 202 208 PF02991 0.371
LIG_LIR_Nem_3 335 341 PF02991 0.395
LIG_LIR_Nem_3 385 391 PF02991 0.348
LIG_LIR_Nem_3 458 462 PF02991 0.349
LIG_LIR_Nem_3 476 481 PF02991 0.289
LIG_LIR_Nem_3 48 52 PF02991 0.514
LIG_LIR_Nem_3 537 543 PF02991 0.367
LIG_LIR_Nem_3 95 101 PF02991 0.273
LIG_MYND_3 107 111 PF01753 0.200
LIG_PTB_Apo_2 245 252 PF02174 0.243
LIG_PTB_Phospho_1 245 251 PF10480 0.252
LIG_RPA_C_Fungi 369 381 PF08784 0.214
LIG_SH2_CRK 375 379 PF00017 0.381
LIG_SH2_CRK 478 482 PF00017 0.446
LIG_SH2_CRK 49 53 PF00017 0.495
LIG_SH2_CRK 588 592 PF00017 0.222
LIG_SH2_GRB2like 246 249 PF00017 0.413
LIG_SH2_GRB2like 588 591 PF00017 0.413
LIG_SH2_SRC 583 586 PF00017 0.392
LIG_SH2_SRC 588 591 PF00017 0.392
LIG_SH2_STAP1 452 456 PF00017 0.218
LIG_SH2_STAP1 459 463 PF00017 0.208
LIG_SH2_STAP1 540 544 PF00017 0.510
LIG_SH2_STAT5 116 119 PF00017 0.275
LIG_SH2_STAT5 185 188 PF00017 0.382
LIG_SH2_STAT5 208 211 PF00017 0.370
LIG_SH2_STAT5 246 249 PF00017 0.321
LIG_SH2_STAT5 251 254 PF00017 0.317
LIG_SH2_STAT5 462 465 PF00017 0.363
LIG_SH2_STAT5 478 481 PF00017 0.355
LIG_SH3_3 102 108 PF00018 0.405
LIG_SH3_3 164 170 PF00018 0.244
LIG_SH3_3 461 467 PF00018 0.351
LIG_SH3_3 478 484 PF00018 0.412
LIG_SH3_3 563 569 PF00018 0.280
LIG_SH3_3 594 600 PF00018 0.377
LIG_SUMO_SIM_anti_2 541 546 PF11976 0.492
LIG_SUMO_SIM_par_1 146 152 PF11976 0.191
LIG_SUMO_SIM_par_1 85 92 PF11976 0.209
LIG_TYR_ITIM 47 52 PF00017 0.497
MOD_CDK_SPK_2 213 218 PF00069 0.413
MOD_CK1_1 127 133 PF00069 0.474
MOD_CK1_1 271 277 PF00069 0.321
MOD_CK1_1 376 382 PF00069 0.363
MOD_CK1_1 433 439 PF00069 0.406
MOD_CK1_1 491 497 PF00069 0.425
MOD_CK1_1 549 555 PF00069 0.344
MOD_CK1_1 610 616 PF00069 0.531
MOD_CK2_1 252 258 PF00069 0.255
MOD_CK2_1 330 336 PF00069 0.416
MOD_CK2_1 391 397 PF00069 0.414
MOD_CK2_1 88 94 PF00069 0.362
MOD_Cter_Amidation 309 312 PF01082 0.258
MOD_GlcNHglycan 126 130 PF01048 0.383
MOD_GlcNHglycan 270 273 PF01048 0.437
MOD_GlcNHglycan 319 322 PF01048 0.355
MOD_GlcNHglycan 430 433 PF01048 0.429
MOD_GlcNHglycan 453 456 PF01048 0.512
MOD_GlcNHglycan 490 493 PF01048 0.303
MOD_GlcNHglycan 609 612 PF01048 0.598
MOD_GlcNHglycan 621 624 PF01048 0.449
MOD_GlcNHglycan 72 75 PF01048 0.759
MOD_GSK3_1 111 118 PF00069 0.319
MOD_GSK3_1 177 184 PF00069 0.363
MOD_GSK3_1 190 197 PF00069 0.346
MOD_GSK3_1 212 219 PF00069 0.313
MOD_GSK3_1 230 237 PF00069 0.272
MOD_GSK3_1 252 259 PF00069 0.264
MOD_GSK3_1 29 36 PF00069 0.484
MOD_GSK3_1 413 420 PF00069 0.260
MOD_GSK3_1 426 433 PF00069 0.310
MOD_GSK3_1 447 454 PF00069 0.402
MOD_GSK3_1 465 472 PF00069 0.324
MOD_GSK3_1 599 606 PF00069 0.598
MOD_GSK3_1 83 90 PF00069 0.357
MOD_LATS_1 532 538 PF00433 0.204
MOD_N-GLC_1 317 322 PF02516 0.399
MOD_N-GLC_1 534 539 PF02516 0.271
MOD_N-GLC_1 70 75 PF02516 0.794
MOD_NEK2_1 149 154 PF00069 0.475
MOD_NEK2_1 289 294 PF00069 0.430
MOD_NEK2_1 301 306 PF00069 0.353
MOD_NEK2_1 317 322 PF00069 0.273
MOD_NEK2_1 401 406 PF00069 0.300
MOD_NEK2_1 426 431 PF00069 0.255
MOD_NEK2_1 469 474 PF00069 0.444
MOD_NEK2_1 485 490 PF00069 0.282
MOD_NEK2_1 519 524 PF00069 0.280
MOD_NEK2_1 619 624 PF00069 0.435
MOD_PIKK_1 256 262 PF00454 0.369
MOD_PIKK_1 33 39 PF00454 0.492
MOD_PIKK_1 519 525 PF00454 0.283
MOD_PKA_2 195 201 PF00069 0.348
MOD_PKA_2 373 379 PF00069 0.380
MOD_PKA_2 440 446 PF00069 0.350
MOD_Plk_1 317 323 PF00069 0.346
MOD_Plk_4 127 133 PF00069 0.360
MOD_Plk_4 144 150 PF00069 0.330
MOD_Plk_4 172 178 PF00069 0.425
MOD_Plk_4 216 222 PF00069 0.371
MOD_Plk_4 291 297 PF00069 0.453
MOD_Plk_4 421 427 PF00069 0.317
MOD_Plk_4 546 552 PF00069 0.354
MOD_ProDKin_1 213 219 PF00069 0.310
MOD_ProDKin_1 419 425 PF00069 0.383
MOD_ProDKin_1 565 571 PF00069 0.408
MOD_ProDKin_1 605 611 PF00069 0.695
MOD_SUMO_for_1 361 364 PF00179 0.342
MOD_SUMO_rev_2 139 147 PF00179 0.297
TRG_ENDOCYTIC_2 21 24 PF00928 0.660
TRG_ENDOCYTIC_2 375 378 PF00928 0.339
TRG_ENDOCYTIC_2 478 481 PF00928 0.438
TRG_ENDOCYTIC_2 49 52 PF00928 0.695
TRG_ENDOCYTIC_2 540 543 PF00928 0.516
TRG_ENDOCYTIC_2 583 586 PF00928 0.375
TRG_ER_diArg_1 167 169 PF00400 0.505
TRG_ER_diArg_1 276 279 PF00400 0.412

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IL11 Leptomonas seymouri 58% 97%
A0A0S4IN60 Bodo saltans 30% 71%
A0A0S4IUT6 Bodo saltans 30% 77%
A0A0S4IYM3 Bodo saltans 33% 87%
A0A1D5NSK0 Danio rerio 25% 100%
A0A1X0NDG7 Trypanosomatidae 31% 97%
A0A1X0NDJ3 Trypanosomatidae 26% 88%
A0A1X0NDK2 Trypanosomatidae 30% 100%
A0A1X0NDK7 Trypanosomatidae 27% 89%
A0A1X0NDK9 Trypanosomatidae 29% 100%
A0A1X0NDM7 Trypanosomatidae 29% 99%
A0A1X0NDU8 Trypanosomatidae 27% 95%
A0A1X0NE71 Trypanosomatidae 29% 100%
A0A1X0NEE9 Trypanosomatidae 28% 69%
A0A1X0NER9 Trypanosomatidae 30% 99%
A0A1X0NET7 Trypanosomatidae 29% 100%
A0A1X0NEX7 Trypanosomatidae 29% 97%
A0A1X0NEZ6 Trypanosomatidae 29% 97%
A0A1X0NF32 Trypanosomatidae 28% 100%
A0A1X0NF41 Trypanosomatidae 31% 100%
A0A1X0NFJ0 Trypanosomatidae 29% 100%
A0A1X0NFK3 Trypanosomatidae 27% 95%
A0A1X0NFL1 Trypanosomatidae 28% 67%
A0A1X0NFS0 Trypanosomatidae 28% 73%
A0A1X0NFT1 Trypanosomatidae 28% 70%
A0A1X0NFU4 Trypanosomatidae 28% 78%
A0A1X0NFZ9 Trypanosomatidae 30% 100%
A0A1X0NG20 Trypanosomatidae 28% 100%
A0A1X0NGP3 Trypanosomatidae 27% 74%
A0A1X0NGY3 Trypanosomatidae 27% 83%
A0A1X0NGZ3 Trypanosomatidae 31% 100%
A0A1X0NH86 Trypanosomatidae 27% 72%
A0A1X0NHP6 Trypanosomatidae 28% 100%
A0A1X0NHQ6 Trypanosomatidae 29% 100%
A0A1X0NI38 Trypanosomatidae 28% 72%
A0A1X0NI74 Trypanosomatidae 29% 85%
A0A1X0NII4 Trypanosomatidae 28% 76%
A0A1X0NIZ3 Trypanosomatidae 32% 100%
A0A1X0NJS3 Trypanosomatidae 31% 97%
A0A1X0NJU4 Trypanosomatidae 29% 74%
A0A1X0NK29 Trypanosomatidae 28% 69%
A0A1X0NK66 Trypanosomatidae 28% 96%
A0A1X0NKJ8 Trypanosomatidae 28% 85%
A0A1X0NKW9 Trypanosomatidae 32% 100%
A0A1X0NME2 Trypanosomatidae 28% 100%
A0A1X0NMK3 Trypanosomatidae 27% 100%
A0A1X0NMK7 Trypanosomatidae 34% 100%
A0A1X0NMV0 Trypanosomatidae 28% 86%
A0A1X0NN43 Trypanosomatidae 29% 89%
A0A1X0NNK8 Trypanosomatidae 26% 97%
A0A1X0NP64 Trypanosomatidae 28% 72%
A0A1X0NPW0 Trypanosomatidae 28% 99%
A0A1X0NQJ5 Trypanosomatidae 31% 100%
A0A1X0NQM4 Trypanosomatidae 31% 100%
A0A1X0NQN3 Trypanosomatidae 33% 100%
A0A1X0NQU4 Trypanosomatidae 33% 99%
A0A1X0NQW6 Trypanosomatidae 31% 100%
A0A1X0NRF3 Trypanosomatidae 29% 95%
A0A1X0NRY8 Trypanosomatidae 32% 100%
A0A1X0NU16 Trypanosomatidae 35% 100%
A0A1X0NUR2 Trypanosomatidae 31% 86%
A0A1X0NV28 Trypanosomatidae 36% 100%
A0A1X0NVC3 Trypanosomatidae 29% 93%
A0A1X0NVE0 Trypanosomatidae 30% 81%
A0A1X0NW07 Trypanosomatidae 26% 100%
A0A1X0NX94 Trypanosomatidae 30% 98%
A0A1X0NX98 Trypanosomatidae 28% 79%
A0A1X0NXB6 Trypanosomatidae 27% 90%
A0A1X0NXH6 Trypanosomatidae 33% 87%
A0A1X0NXQ4 Trypanosomatidae 30% 94%
A0A1X0NXR7 Trypanosomatidae 35% 85%
A0A1X0NY94 Trypanosomatidae 35% 100%
A0A1X0NYE3 Trypanosomatidae 31% 100%
A0A1X0NYE7 Trypanosomatidae 31% 100%
A0A1X0NYN2 Trypanosomatidae 32% 100%
A0A1X0NYN4 Trypanosomatidae 28% 89%
A0A1X0NYS5 Trypanosomatidae 32% 100%
A0A1X0NYZ2 Trypanosomatidae 37% 100%
A0A1X0NZ46 Trypanosomatidae 28% 100%
A0A1X0NZ63 Trypanosomatidae 29% 100%
A0A1X0NZN6 Trypanosomatidae 29% 98%
A0A1X0P055 Trypanosomatidae 33% 100%
A0A1X0P154 Trypanosomatidae 30% 100%
A0A1X0P331 Trypanosomatidae 34% 100%
A0A1X0P3K0 Trypanosomatidae 27% 87%
A0A1X0P3S2 Trypanosomatidae 27% 100%
A0A1X0P4L8 Trypanosomatidae 27% 100%
A0A1X0P4Y5 Trypanosomatidae 28% 99%
A0A1X0P544 Trypanosomatidae 31% 99%
A0A1X0P5J0 Trypanosomatidae 31% 93%
A0A1X0P7K5 Trypanosomatidae 29% 72%
A0A1X0P7R3 Trypanosomatidae 37% 100%
A0A1X0P8B4 Trypanosomatidae 29% 100%
A0A1X0P9Z4 Trypanosomatidae 29% 100%
A0A1X0PB04 Trypanosomatidae 30% 100%
A0A3Q8I8N3 Leishmania donovani 36% 100%
A0A3Q8I8P8 Leishmania donovani 36% 100%
A0A3Q8I8S6 Leishmania donovani 36% 99%
A0A3Q8I8S9 Leishmania donovani 35% 100%
A0A3Q8IAZ8 Leishmania donovani 36% 100%
A0A3Q8IC35 Leishmania donovani 36% 100%
A0A3Q8IC44 Leishmania donovani 35% 100%
A0A3Q8IH61 Leishmania donovani 35% 100%
A0A3Q8IIN4 Leishmania donovani 95% 100%
A0A3R7JT49 Trypanosoma rangeli 34% 75%
A0A3R7JTB6 Trypanosoma rangeli 31% 90%
A0A3R7JV87 Trypanosoma rangeli 34% 100%
A0A3R7K7T9 Trypanosoma rangeli 32% 100%
A0A3R7K9S1 Trypanosoma rangeli 34% 100%
A0A3R7KB14 Trypanosoma rangeli 32% 72%
A0A3R7KLR6 Trypanosoma rangeli 31% 99%
A0A3R7KMY2 Trypanosoma rangeli 36% 95%
A0A3R7LFC4 Trypanosoma rangeli 36% 94%
A0A3R7LFZ4 Trypanosoma rangeli 38% 100%
A0A3R7LWG1 Trypanosoma rangeli 31% 100%
A0A3R7LX11 Trypanosoma rangeli 36% 100%
A0A3R7M1R8 Trypanosoma rangeli 35% 100%
A0A3R7M574 Trypanosoma rangeli 36% 99%
A0A3R7M7N6 Trypanosoma rangeli 35% 92%
A0A3R7MTS2 Trypanosoma rangeli 38% 100%
A0A3R7MW36 Trypanosoma rangeli 34% 100%
A0A3R7MXF4 Trypanosoma rangeli 35% 100%
A0A3R7N1W7 Trypanosoma rangeli 31% 100%
A0A3R7N289 Trypanosoma rangeli 36% 88%
A0A3R7NTI8 Trypanosoma rangeli 34% 100%
A0A3R7R2J4 Trypanosoma rangeli 35% 98%
A0A3R7R5R1 Trypanosoma rangeli 32% 100%
A0A3R7R818 Trypanosoma rangeli 32% 100%
A0A3S5H6G0 Leishmania donovani 35% 100%
A0A3S5IQY2 Trypanosoma rangeli 37% 100%
A0A3S7WR43 Leishmania donovani 36% 100%
A0A3S7WR46 Leishmania donovani 36% 100%
A0A3S7WR60 Leishmania donovani 36% 100%
A0A3S7X192 Leishmania donovani 42% 100%
A0A422MP17 Trypanosoma rangeli 33% 100%
A0A422MRQ6 Trypanosoma rangeli 35% 85%
A0A422MU95 Trypanosoma rangeli 35% 100%
A0A422MVF5 Trypanosoma rangeli 31% 100%
A0A422MVS3 Trypanosoma rangeli 31% 100%
A0A422MW99 Trypanosoma rangeli 28% 85%
A0A422MZ47 Trypanosoma rangeli 39% 100%
A0A422MZG4 Trypanosoma rangeli 34% 100%
A0A422N361 Trypanosoma rangeli 34% 100%
A0A422N7Q6 Trypanosoma rangeli 36% 98%
A0A422NDS2 Trypanosoma rangeli 34% 100%
A0A422NDT3 Trypanosoma rangeli 30% 100%
A0A422NP82 Trypanosoma rangeli 38% 100%
A4H626 Leishmania braziliensis 36% 100%
A4H627 Leishmania braziliensis 33% 100%
A4H630 Leishmania braziliensis 37% 100%
A4H631 Leishmania braziliensis 37% 100%
A4H632 Leishmania braziliensis 35% 100%
A4H633 Leishmania braziliensis 40% 100%
A4H634 Leishmania braziliensis 38% 100%
A4H635 Leishmania braziliensis 37% 100%
A4H636 Leishmania braziliensis 33% 100%
A4H637 Leishmania braziliensis 38% 100%
A4H638 Leishmania braziliensis 38% 100%
A4H639 Leishmania braziliensis 36% 100%
A4H640 Leishmania braziliensis 38% 100%
A4H6D3 Leishmania braziliensis 34% 100%
A4H6D5 Leishmania braziliensis 36% 90%
A4H6D7 Leishmania braziliensis 33% 100%
A4H6D8 Leishmania braziliensis 35% 100%
A4H6D9 Leishmania braziliensis 36% 100%
A4H6E0 Leishmania braziliensis 36% 89%
A4H6E1 Leishmania braziliensis 33% 100%
A4H6E2 Leishmania braziliensis 34% 100%
A4H6E3 Leishmania braziliensis 36% 100%
A4H6E5 Leishmania braziliensis 40% 100%
A4HJI2 Leishmania braziliensis 79% 98%
A4HUF6 Leishmania infantum 37% 100%
A4HUF8 Leishmania infantum 35% 100%
A4HUF9 Leishmania infantum 36% 99%
A4HUG0 Leishmania infantum 35% 83%
A4I6X5 Leishmania infantum 95% 100%
C9ZUT5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 36% 100%
D0A1R8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 100%
D0A7S8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 28% 94%
D0A855 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 35% 100%
E9AHH5 Leishmania infantum 42% 100%
E9AN53 Leishmania mexicana (strain MHOM/GT/2001/U1103) 37% 97%
E9AN54 Leishmania mexicana (strain MHOM/GT/2001/U1103) 37% 100%
E9AN55 Leishmania mexicana (strain MHOM/GT/2001/U1103) 37% 99%
E9AN56 Leishmania mexicana (strain MHOM/GT/2001/U1103) 37% 98%
E9AN57 Leishmania mexicana (strain MHOM/GT/2001/U1103) 38% 100%
E9AZL8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 41% 100%
E9B1Z9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%
O62446 Caenorhabditis elegans 24% 96%
P08148 Leishmania major 37% 100%
P15706 Leishmania chagasi 35% 100%
P23223 Leishmania donovani 37% 100%
P43150 Leishmania mexicana 37% 98%
Q00689 Leishmania guyanensis 38% 100%
Q06031 Crithidia fasciculata 35% 97%
Q27673 Leishmania amazonensis 36% 100%
Q29AK2 Drosophila pseudoobscura pseudoobscura 23% 93%
Q4Q8L3 Leishmania major 42% 100%
Q4QHG9 Leishmania major 38% 100%
Q4QHH0 Leishmania major 37% 99%
Q4QHH1 Leishmania major 38% 100%
Q4QHH2 Leishmania major 37% 100%
Q61YG1 Caenorhabditis briggsae 24% 96%
Q6LA77 Leishmania infantum 35% 100%
Q8BMN4 Mus musculus 23% 93%
Q8MNZ1 Leishmania tropica 36% 97%
Q96KR4 Homo sapiens 22% 97%
Q9VH19 Drosophila melanogaster 24% 93%
V5A359 Trypanosoma cruzi 39% 100%
V5A488 Trypanosoma cruzi 31% 79%
V5AII7 Trypanosoma cruzi 38% 100%
V5APQ4 Trypanosoma cruzi 30% 80%
V5AX72 Trypanosoma cruzi 32% 86%
V5B5M0 Trypanosoma cruzi 32% 86%
V5B9W5 Trypanosoma cruzi 28% 94%
V5BAN1 Trypanosoma cruzi 32% 81%
V5BLT3 Trypanosoma cruzi 33% 100%
V5CI97 Trypanosoma cruzi 30% 100%
V5D358 Trypanosoma cruzi 33% 75%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS