Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q653_LEIMA

TriTrypDb:

LmjF.31.2090 , LMJLV39_310029600 , LMJSD75_310029600

Length:

383

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q653

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q653

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	176	178	PF00675	0.574
CLV_NRD_NRD_1	192	194	PF00675	0.522
CLV_NRD_NRD_1	204	206	PF00675	0.588
CLV_NRD_NRD_1	212	214	PF00675	0.465
CLV_NRD_NRD_1	260	262	PF00675	0.599
CLV_NRD_NRD_1	28	30	PF00675	0.664
CLV_NRD_NRD_1	57	59	PF00675	0.698
CLV_PCSK_KEX2_1	204	206	PF00082	0.650
CLV_PCSK_KEX2_1	212	214	PF00082	0.463
CLV_PCSK_KEX2_1	260	262	PF00082	0.599
CLV_PCSK_KEX2_1	28	30	PF00082	0.669
CLV_PCSK_KEX2_1	57	59	PF00082	0.617
CLV_PCSK_SKI1_1	205	209	PF00082	0.540
CLV_PCSK_SKI1_1	213	217	PF00082	0.537
CLV_PCSK_SKI1_1	284	288	PF00082	0.570
CLV_PCSK_SKI1_1	291	295	PF00082	0.595
DEG_APCC_DBOX_1	192	200	PF00400	0.531
DEG_SCF_FBW7_1	228	235	PF00400	0.624
DOC_MAPK_gen_1	201	210	PF00069	0.617
DOC_PP4_FxxP_1	163	166	PF00568	0.650
DOC_USP7_MATH_1	125	129	PF00917	0.702
DOC_USP7_MATH_1	262	266	PF00917	0.672
DOC_USP7_MATH_1	27	31	PF00917	0.712
DOC_USP7_MATH_1	273	277	PF00917	0.788
DOC_USP7_MATH_1	322	326	PF00917	0.646
DOC_WW_Pin1_4	140	145	PF00397	0.809
DOC_WW_Pin1_4	146	151	PF00397	0.657
DOC_WW_Pin1_4	19	24	PF00397	0.808
DOC_WW_Pin1_4	228	233	PF00397	0.681
DOC_WW_Pin1_4	267	272	PF00397	0.669
LIG_14-3-3_CanoR_1	177	182	PF00244	0.558
LIG_14-3-3_CanoR_1	18	23	PF00244	0.739
LIG_14-3-3_CanoR_1	205	211	PF00244	0.659
LIG_14-3-3_CanoR_1	227	232	PF00244	0.508
LIG_14-3-3_CanoR_1	28	36	PF00244	0.664
LIG_14-3-3_CanoR_1	291	300	PF00244	0.616
LIG_14-3-3_CanoR_1	335	344	PF00244	0.652
LIG_14-3-3_CanoR_1	47	56	PF00244	0.636
LIG_Clathr_ClatBox_1	286	290	PF01394	0.553
LIG_CtBP_PxDLS_1	124	128	PF00389	0.667
LIG_LIR_Apic_2	161	166	PF02991	0.659
LIG_LIR_Gen_1	180	189	PF02991	0.590
LIG_LIR_Gen_1	242	250	PF02991	0.552
LIG_LIR_Gen_1	290	301	PF02991	0.611
LIG_LIR_Gen_1	309	318	PF02991	0.582
LIG_LIR_Gen_1	321	329	PF02991	0.631
LIG_LIR_Gen_1	65	71	PF02991	0.651
LIG_LIR_Gen_1	96	103	PF02991	0.600
LIG_LIR_Nem_3	180	185	PF02991	0.613
LIG_LIR_Nem_3	242	247	PF02991	0.568
LIG_LIR_Nem_3	290	296	PF02991	0.603
LIG_LIR_Nem_3	309	314	PF02991	0.587
LIG_LIR_Nem_3	321	326	PF02991	0.632
LIG_LIR_Nem_3	65	70	PF02991	0.621
LIG_LIR_Nem_3	96	102	PF02991	0.519
LIG_PCNA_yPIPBox_3	299	312	PF02747	0.640
LIG_PDZ_Class_1	378	383	PF00595	0.688
LIG_Pex14_2	244	248	PF04695	0.594
LIG_Pex14_2	323	327	PF04695	0.570
LIG_SH2_CRK	67	71	PF00017	0.563
LIG_SH2_NCK_1	63	67	PF00017	0.571
LIG_SH2_STAP1	67	71	PF00017	0.640
LIG_SH2_STAT5	162	165	PF00017	0.584
LIG_SH2_STAT5	234	237	PF00017	0.516
LIG_SH2_STAT5	285	288	PF00017	0.512
LIG_SH2_STAT5	355	358	PF00017	0.603
LIG_SH3_1	358	364	PF00018	0.647
LIG_SH3_3	119	125	PF00018	0.582
LIG_SH3_3	138	144	PF00018	0.514
LIG_SH3_3	341	347	PF00018	0.641
LIG_SH3_3	358	364	PF00018	0.596
LIG_SH3_5	158	162	PF00018	0.668
LIG_SUMO_SIM_anti_2	74	81	PF11976	0.521
LIG_SUMO_SIM_par_1	206	211	PF11976	0.610
MOD_CDK_SPK_2	146	151	PF00069	0.593
MOD_CK1_1	149	155	PF00069	0.798
MOD_CK1_1	180	186	PF00069	0.629
MOD_CK1_1	30	36	PF00069	0.665
MOD_CK1_1	50	56	PF00069	0.783
MOD_CK2_1	189	195	PF00069	0.550
MOD_CK2_1	335	341	PF00069	0.646
MOD_CMANNOS	327	330	PF00535	0.563
MOD_GlcNHglycan	279	282	PF01048	0.757
MOD_GlcNHglycan	351	354	PF01048	0.695
MOD_GlcNHglycan	380	383	PF01048	0.664
MOD_GSK3_1	173	180	PF00069	0.624
MOD_GSK3_1	228	235	PF00069	0.636
MOD_GSK3_1	27	34	PF00069	0.708
MOD_GSK3_1	273	280	PF00069	0.641
MOD_GSK3_1	312	319	PF00069	0.743
MOD_NEK2_1	173	178	PF00069	0.579
MOD_NEK2_1	277	282	PF00069	0.631
MOD_NEK2_1	31	36	PF00069	0.568
MOD_NEK2_2	115	120	PF00069	0.579
MOD_PIKK_1	180	186	PF00454	0.612
MOD_PIKK_1	248	254	PF00454	0.597
MOD_PIKK_1	50	56	PF00454	0.645
MOD_PKA_1	177	183	PF00069	0.530
MOD_PKA_2	189	195	PF00069	0.481
MOD_PKA_2	27	33	PF00069	0.629
MOD_PKA_2	334	340	PF00069	0.586
MOD_PKA_2	48	54	PF00069	0.624
MOD_Plk_1	125	131	PF00069	0.602
MOD_Plk_1	289	295	PF00069	0.630
MOD_Plk_4	177	183	PF00069	0.578
MOD_Plk_4	322	328	PF00069	0.518
MOD_Plk_4	75	81	PF00069	0.511
MOD_ProDKin_1	140	146	PF00069	0.810
MOD_ProDKin_1	19	25	PF00069	0.811
MOD_ProDKin_1	228	234	PF00069	0.675
MOD_ProDKin_1	267	273	PF00069	0.663
MOD_SUMO_rev_2	337	345	PF00179	0.651
TRG_DiLeu_BaEn_2	340	346	PF01217	0.593
TRG_ENDOCYTIC_2	67	70	PF00928	0.565
TRG_ER_diArg_1	185	188	PF00400	0.630
TRG_ER_diArg_1	260	262	PF00400	0.589
TRG_ER_diArg_1	46	49	PF00400	0.690
TRG_ER_diArg_1	56	58	PF00400	0.589
TRG_NES_CRM1_1	239	253	PF08389	0.572
TRG_Pf-PMV_PEXEL_1	238	242	PF00026	0.619

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I674	Leptomonas seymouri	47%	76%
A0A3Q8IGG7	Leishmania donovani	94%	100%
A4I6Y7	Leishmania infantum	93%	100%
E9B208	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	100%