LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania major
UniProt:
Q4Q637_LEIMA
TriTrypDb:
LmjF.31.2240 , LMJLV39_310031700 , LMJSD75_310031700
Length:
152

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 4
GO:0110165 cellular anatomical entity 1 4
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Expansion

Sequence features

Q4Q637
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q637

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 116 118 PF00675 0.492
CLV_NRD_NRD_1 52 54 PF00675 0.424
CLV_PCSK_KEX2_1 116 118 PF00082 0.492
CLV_PCSK_KEX2_1 47 49 PF00082 0.432
CLV_PCSK_PC1ET2_1 47 49 PF00082 0.432
CLV_PCSK_PC7_1 112 118 PF00082 0.476
CLV_PCSK_SKI1_1 47 51 PF00082 0.429
DOC_CKS1_1 68 73 PF01111 0.678
DOC_CYCLIN_yCln2_LP_2 14 20 PF00134 0.389
DOC_PP2B_LxvP_1 14 17 PF13499 0.389
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3Q8IGB0 Leishmania donovani 87% 100%
A4I707 Leishmania infantum 87% 100%
E9B225 Leishmania mexicana (strain MHOM/GT/2001/U1103) 81% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS