Death domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q620_LEIMA

TriTrypDb:

LmjF.31.2410 , LMJLV39_310033600 , LMJSD75_310033600

Length:

336

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q620

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q620

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	123	129	PF00089	0.808
CLV_NRD_NRD_1	54	56	PF00675	0.805
CLV_PCSK_KEX2_1	227	229	PF00082	0.823
CLV_PCSK_KEX2_1	54	56	PF00082	0.805
CLV_PCSK_PC1ET2_1	227	229	PF00082	0.823
DEG_Nend_UBRbox_2	1	3	PF02207	0.800
DEG_SCF_FBW7_1	185	191	PF00400	0.833
DEG_SPOP_SBC_1	258	262	PF00917	0.829
DEG_SPOP_SBC_1	34	38	PF00917	0.822
DOC_CKS1_1	185	190	PF01111	0.833
DOC_CYCLIN_yClb3_PxF_3	216	222	PF00134	0.831
DOC_CYCLIN_yCln2_LP_2	211	217	PF00134	0.837
DOC_PP2B_LxvP_1	175	178	PF13499	0.820
DOC_PP2B_LxvP_1	31	34	PF13499	0.827
DOC_PP4_FxxP_1	116	119	PF00568	0.811
DOC_PP4_FxxP_1	189	192	PF00568	0.842
DOC_USP7_MATH_1	132	136	PF00917	0.826
DOC_USP7_MATH_1	258	262	PF00917	0.829
DOC_USP7_MATH_1	264	268	PF00917	0.729
DOC_USP7_MATH_1	286	290	PF00917	0.819
DOC_USP7_MATH_1	34	38	PF00917	0.822
DOC_USP7_MATH_1	39	43	PF00917	0.727
DOC_USP7_MATH_1	76	80	PF00917	0.845
DOC_WW_Pin1_4	115	120	PF00397	0.810
DOC_WW_Pin1_4	125	130	PF00397	0.635
DOC_WW_Pin1_4	184	189	PF00397	0.830
DOC_WW_Pin1_4	20	25	PF00397	0.802
DOC_WW_Pin1_4	203	208	PF00397	0.522
DOC_WW_Pin1_4	35	40	PF00397	0.557
LIG_14-3-3_CanoR_1	117	127	PF00244	0.810
LIG_14-3-3_CanoR_1	199	207	PF00244	0.856
LIG_14-3-3_CanoR_1	35	39	PF00244	0.819
LIG_14-3-3_CanoR_1	60	68	PF00244	0.804
LIG_14-3-3_CanoR_1	80	86	PF00244	0.492
LIG_BRCT_BRCA1_1	112	116	PF00533	0.808
LIG_BRCT_BRCA1_1	6	10	PF00533	0.799
LIG_deltaCOP1_diTrp_1	99	108	PF00928	0.812
LIG_FHA_1	251	257	PF00498	0.819
LIG_FHA_1	258	264	PF00498	0.707
LIG_FHA_1	269	275	PF00498	0.488
LIG_FHA_2	193	199	PF00498	0.847
LIG_FHA_2	92	98	PF00498	0.842
LIG_LIR_Apic_2	113	119	PF02991	0.808
LIG_LIR_Apic_2	187	192	PF02991	0.834
LIG_LIR_Gen_1	118	127	PF02991	0.808
LIG_LIR_Gen_1	221	229	PF02991	0.831
LIG_LIR_Gen_1	231	238	PF02991	0.631
LIG_LIR_Gen_1	273	284	PF02991	0.810
LIG_LIR_Nem_3	118	123	PF02991	0.475
LIG_LIR_Nem_3	125	130	PF02991	0.687
LIG_LIR_Nem_3	221	225	PF02991	0.841
LIG_LIR_Nem_3	273	279	PF02991	0.808
LIG_LIR_Nem_3	99	105	PF02991	0.813
LIG_PDZ_Class_2	331	336	PF00595	0.731
LIG_Pex14_2	10	14	PF04695	0.809
LIG_Pex14_2	116	120	PF04695	0.813
LIG_SH2_STAT5	304	307	PF00017	0.773
LIG_SH3_1	18	24	PF00018	0.799
LIG_SH3_3	175	181	PF00018	0.819
LIG_SH3_3	18	24	PF00018	0.799
LIG_SH3_3	182	188	PF00018	0.705
LIG_SH3_3	211	217	PF00018	0.837
LIG_SH3_3	50	56	PF00018	0.815
LIG_SH3_3	83	89	PF00018	0.832
LIG_WRC_WIRS_1	229	234	PF05994	0.811
LIG_WW_2	88	91	PF00397	0.841
LIG_WW_3	206	210	PF00397	0.847
MOD_CDC14_SPxK_1	206	209	PF00782	0.847
MOD_CDK_SPxK_1	203	209	PF00069	0.855
MOD_CK1_1	110	116	PF00069	0.806
MOD_CK1_1	118	124	PF00069	0.667
MOD_CK1_1	125	131	PF00069	0.549
MOD_CK1_1	23	29	PF00069	0.814
MOD_CK1_1	240	246	PF00069	0.801
MOD_CK1_1	257	263	PF00069	0.532
MOD_CK1_1	267	273	PF00069	0.635
MOD_CK1_1	37	43	PF00069	0.572
MOD_CK1_1	81	87	PF00069	0.837
MOD_CK2_1	91	97	PF00069	0.845
MOD_GlcNHglycan	109	112	PF01048	0.805
MOD_GlcNHglycan	182	185	PF01048	0.825
MOD_GlcNHglycan	256	259	PF01048	0.830
MOD_GlcNHglycan	267	270	PF01048	0.623
MOD_GlcNHglycan	39	42	PF01048	0.813
MOD_GlcNHglycan	7	10	PF01048	0.801
MOD_GlcNHglycan	80	83	PF01048	0.851
MOD_GSK3_1	115	122	PF00069	0.809
MOD_GSK3_1	139	146	PF00069	0.832
MOD_GSK3_1	180	187	PF00069	0.826
MOD_GSK3_1	188	195	PF00069	0.696
MOD_GSK3_1	199	206	PF00069	0.525
MOD_GSK3_1	237	244	PF00069	0.803
MOD_GSK3_1	250	257	PF00069	0.590
MOD_GSK3_1	264	271	PF00069	0.578
MOD_GSK3_1	33	40	PF00069	0.820
MOD_NEK2_1	143	148	PF00069	0.822
MOD_NEK2_1	241	246	PF00069	0.801
MOD_NEK2_1	254	259	PF00069	0.596
MOD_NEK2_1	61	66	PF00069	0.805
MOD_NEK2_1	67	72	PF00069	0.689
MOD_PIKK_1	215	221	PF00454	0.830
MOD_PIKK_1	81	87	PF00454	0.837
MOD_PKA_2	198	204	PF00069	0.856
MOD_PKA_2	34	40	PF00069	0.817
MOD_PKB_1	197	205	PF00069	0.859
MOD_Plk_1	249	255	PF00069	0.811
MOD_Plk_4	119	125	PF00069	0.806
MOD_Plk_4	237	243	PF00069	0.806
MOD_ProDKin_1	115	121	PF00069	0.810
MOD_ProDKin_1	125	131	PF00069	0.637
MOD_ProDKin_1	184	190	PF00069	0.833
MOD_ProDKin_1	20	26	PF00069	0.804
MOD_ProDKin_1	203	209	PF00069	0.523
MOD_ProDKin_1	35	41	PF00069	0.557
MOD_SUMO_rev_2	307	314	PF00179	0.775
TRG_DiLeu_BaEn_1	237	242	PF01217	0.806
TRG_DiLeu_BaLyEn_6	57	62	PF01217	0.796
TRG_ER_diArg_1	53	55	PF00400	0.808