LeishMANIAdb
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Death domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Download

Quick info

Protein:
Death domain-containing protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania major
UniProt:
Q4Q620_LEIMA
TriTrypDb:
LmjF.31.2410 * , LMJLV39_310033600 * , LMJSD75_310033600 *
Length:
336

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 1
NetGPI no yes: 0, no: 1
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q620
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q620

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_MEL_PAP_1 123 129 PF00089 0.808
CLV_NRD_NRD_1 54 56 PF00675 0.805
CLV_PCSK_KEX2_1 227 229 PF00082 0.823
CLV_PCSK_KEX2_1 54 56 PF00082 0.805
CLV_PCSK_PC1ET2_1 227 229 PF00082 0.823
DEG_Nend_UBRbox_2 1 3 PF02207 0.800
DEG_SCF_FBW7_1 185 191 PF00400 0.833
DEG_SPOP_SBC_1 258 262 PF00917 0.829
DEG_SPOP_SBC_1 34 38 PF00917 0.822
DOC_CKS1_1 185 190 PF01111 0.833
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS