Ribosomal_S10 domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q616_LEIMA

TriTrypDb:

LmjF.31.2450 , LMJLV39_310034000 , LMJSD75_310034000

Length:

236

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 3
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 14
NetGPI	no	yes: 0, no: 14

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q616

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q616

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	18	20	PF00675	0.435
CLV_PCSK_SKI1_1	10	14	PF00082	0.427
CLV_PCSK_SKI1_1	102	106	PF00082	0.473
CLV_PCSK_SKI1_1	220	224	PF00082	0.650
DOC_CYCLIN_yClb5_NLxxxL_5	214	223	PF00134	0.489
DOC_CYCLIN_yCln2_LP_2	12	18	PF00134	0.422
DOC_CYCLIN_yCln2_LP_2	210	216	PF00134	0.521
DOC_MAPK_gen_1	149	159	PF00069	0.332
DOC_PP2B_LxvP_1	12	15	PF13499	0.422
DOC_USP7_UBL2_3	101	105	PF12436	0.459
DOC_WW_Pin1_4	23	28	PF00397	0.468
LIG_BRCT_BRCA1_1	35	39	PF00533	0.463
LIG_FHA_1	133	139	PF00498	0.584
LIG_FHA_1	152	158	PF00498	0.441
LIG_FHA_1	188	194	PF00498	0.513
LIG_FHA_1	199	205	PF00498	0.513
LIG_FHA_1	28	34	PF00498	0.514
LIG_FHA_1	57	63	PF00498	0.396
LIG_FHA_2	175	181	PF00498	0.623
LIG_IRF3_LxIS_1	29	36	PF10401	0.464
LIG_LIR_Gen_1	151	159	PF02991	0.461
LIG_LIR_Gen_1	180	187	PF02991	0.640
LIG_LIR_Gen_1	36	47	PF02991	0.369
LIG_LIR_Nem_3	180	185	PF02991	0.471
LIG_Pex14_1	155	159	PF04695	0.364
LIG_SH2_CRK	182	186	PF00017	0.478
LIG_SH2_CRK	216	220	PF00017	0.532
LIG_SH2_STAP1	153	157	PF00017	0.379
LIG_SH2_STAT5	143	146	PF00017	0.484
LIG_SH2_STAT5	153	156	PF00017	0.329
LIG_SH2_STAT5	21	24	PF00017	0.451
LIG_SH3_2	15	20	PF14604	0.427
LIG_SH3_3	12	18	PF00018	0.422
LIG_SH3_3	219	225	PF00018	0.719
LIG_SH3_3	26	32	PF00018	0.471
LIG_TYR_ITIM	214	219	PF00017	0.501
MOD_CK1_1	107	113	PF00069	0.513
MOD_CK1_1	174	180	PF00069	0.599
MOD_CK2_1	106	112	PF00069	0.470
MOD_CK2_1	174	180	PF00069	0.599
MOD_GlcNHglycan	132	135	PF01048	0.580
MOD_GSK3_1	104	111	PF00069	0.447
MOD_GSK3_1	23	30	PF00069	0.442
MOD_N-GLC_1	180	185	PF02516	0.496
MOD_NEK2_1	171	176	PF00069	0.447
MOD_NEK2_1	33	38	PF00069	0.492
MOD_NEK2_1	88	93	PF00069	0.447
MOD_NEK2_2	141	146	PF00069	0.416
MOD_NEK2_2	61	66	PF00069	0.269
MOD_PIKK_1	187	193	PF00454	0.485
MOD_PKA_2	141	147	PF00069	0.458
MOD_PKA_2	88	94	PF00069	0.360
MOD_Plk_1	180	186	PF00069	0.505
MOD_Plk_2-3	203	209	PF00069	0.562
MOD_Plk_4	151	157	PF00069	0.526
MOD_Plk_4	180	186	PF00069	0.555
MOD_ProDKin_1	23	29	PF00069	0.468
TRG_DiLeu_BaEn_2	204	210	PF01217	0.528
TRG_ENDOCYTIC_2	153	156	PF00928	0.493
TRG_ENDOCYTIC_2	162	165	PF00928	0.436
TRG_ENDOCYTIC_2	182	185	PF00928	0.580
TRG_ENDOCYTIC_2	21	24	PF00928	0.469
TRG_ENDOCYTIC_2	216	219	PF00928	0.568
TRG_ER_diArg_1	77	80	PF00400	0.411

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I730	Leptomonas seymouri	43%	100%
A0A0N1I8Q6	Leptomonas seymouri	25%	100%
A0A0N1PCW5	Leptomonas seymouri	24%	100%
A0A3Q8IF19	Leishmania donovani	22%	100%
A0A3Q8IKA6	Leishmania donovani	83%	100%
A0A3S5H7Q5	Leishmania donovani	23%	100%
A4HJM9	Leishmania braziliensis	56%	100%
A4I749	Leishmania infantum	23%	100%
A4I750	Leishmania infantum	23%	100%
A4I751	Leishmania infantum	83%	100%
E9B244	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9B245	Leishmania mexicana (strain MHOM/GT/2001/U1103)	75%	100%
Q4Q617	Leishmania major	22%	100%