Serine/threonine-protein phosphatase

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

serine/threonine protein phosphatase pp1(5.9), putative

Species:

Leishmania major

UniProt:

Q4Q5Z8_LEIMA

TriTrypDb:

LmjF.31.2630 , LMJLV39_310035800 , LMJSD75_310035800

Length:

365

Annotations

LeishMANIAdb annotations

A large collection of various protein phosphatases. Very highly expanded in kinetoplastids.

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	2
GO:0005737	cytoplasm	2	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4Q5Z8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q5Z8

Function

Could not find GO biological_process term for this entry.

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	7
GO:0004721	phosphoprotein phosphatase activity	3	7
GO:0004722	protein serine/threonine phosphatase activity	4	7
GO:0005488	binding	1	7
GO:0016787	hydrolase activity	2	7
GO:0016788	hydrolase activity, acting on ester bonds	3	7
GO:0016791	phosphatase activity	5	7
GO:0017018	myosin phosphatase activity	5	7
GO:0042578	phosphoric ester hydrolase activity	4	7
GO:0043167	ion binding	2	7
GO:0043169	cation binding	3	7
GO:0046872	metal ion binding	4	7
GO:0140096	catalytic activity, acting on a protein	2	7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	252	256	PF00656	0.380
CLV_NRD_NRD_1	100	102	PF00675	0.315
CLV_NRD_NRD_1	200	202	PF00675	0.380
CLV_NRD_NRD_1	245	247	PF00675	0.369
CLV_NRD_NRD_1	319	321	PF00675	0.419
CLV_PCSK_KEX2_1	199	201	PF00082	0.380
CLV_PCSK_KEX2_1	245	247	PF00082	0.369
CLV_PCSK_KEX2_1	26	28	PF00082	0.650
CLV_PCSK_KEX2_1	319	321	PF00082	0.461
CLV_PCSK_PC1ET2_1	199	201	PF00082	0.380
CLV_PCSK_PC1ET2_1	26	28	PF00082	0.650
CLV_PCSK_PC1ET2_1	319	321	PF00082	0.461
CLV_PCSK_SKI1_1	101	105	PF00082	0.275
CLV_PCSK_SKI1_1	13	17	PF00082	0.442
CLV_PCSK_SKI1_1	208	212	PF00082	0.380
CLV_PCSK_SKI1_1	245	249	PF00082	0.380
CLV_PCSK_SKI1_1	320	324	PF00082	0.417
DEG_Nend_Nbox_1	1	3	PF02207	0.467
DOC_CYCLIN_RxL_1	315	327	PF00134	0.509
DOC_MAPK_gen_1	199	206	PF00069	0.333
DOC_MAPK_gen_1	319	325	PF00069	0.379
DOC_PP1_RVXF_1	167	173	PF00149	0.380
DOC_PP1_RVXF_1	278	285	PF00149	0.380
DOC_PP4_FxxP_1	326	329	PF00568	0.391
DOC_USP7_MATH_1	32	36	PF00917	0.548
DOC_USP7_UBL2_3	315	319	PF12436	0.469
DOC_WW_Pin1_4	232	237	PF00397	0.380
DOC_WW_Pin1_4	28	33	PF00397	0.684
LIG_14-3-3_CanoR_1	200	205	PF00244	0.380
LIG_14-3-3_CanoR_1	280	285	PF00244	0.380
LIG_14-3-3_CanoR_1	320	326	PF00244	0.406
LIG_14-3-3_CanoR_1	70	80	PF00244	0.671
LIG_Actin_WH2_2	234	251	PF00022	0.380
LIG_AP2alpha_1	210	214	PF02296	0.380
LIG_BRCT_BRCA1_1	282	286	PF00533	0.380
LIG_Clathr_ClatBox_1	110	114	PF01394	0.508
LIG_Clathr_ClatBox_1	358	362	PF01394	0.465
LIG_DCNL_PONY_1	1	4	PF03556	0.444
LIG_FHA_1	159	165	PF00498	0.480
LIG_FHA_1	20	26	PF00498	0.454
LIG_FHA_1	293	299	PF00498	0.397
LIG_FHA_1	67	73	PF00498	0.716
LIG_FHA_2	283	289	PF00498	0.380
LIG_FHA_2	87	93	PF00498	0.380
LIG_GBD_Chelix_1	290	298	PF00786	0.480
LIG_Integrin_isoDGR_2	224	226	PF01839	0.261
LIG_LIR_Apic_2	261	267	PF02991	0.380
LIG_LIR_Apic_2	324	329	PF02991	0.389
LIG_LIR_Gen_1	142	152	PF02991	0.380
LIG_LIR_Gen_1	211	222	PF02991	0.380
LIG_LIR_Gen_1	92	103	PF02991	0.515
LIG_LIR_Nem_3	142	148	PF02991	0.359
LIG_LIR_Nem_3	311	317	PF02991	0.436
LIG_LIR_Nem_3	334	338	PF02991	0.451
LIG_MAD2	246	254	PF02301	0.369
LIG_Pex14_2	172	176	PF04695	0.380
LIG_Pex14_2	210	214	PF04695	0.380
LIG_PTB_Apo_2	171	178	PF02174	0.436
LIG_REV1ctd_RIR_1	174	184	PF16727	0.380
LIG_REV1ctd_RIR_1	314	325	PF16727	0.421
LIG_SH2_PTP2	145	148	PF00017	0.380
LIG_SH2_STAP1	202	206	PF00017	0.480
LIG_SH2_STAT5	145	148	PF00017	0.359
LIG_SH2_STAT5	151	154	PF00017	0.380
LIG_SH2_STAT5	331	334	PF00017	0.444
LIG_SH2_STAT5	95	98	PF00017	0.515
LIG_SH2_STAT6	313	317	PF00017	0.459
LIG_SUMO_SIM_anti_2	299	304	PF11976	0.380
LIG_SUMO_SIM_par_1	109	114	PF11976	0.508
LIG_SUMO_SIM_par_1	321	327	PF11976	0.394
LIG_TRAF2_1	89	92	PF00917	0.515
LIG_UBA3_1	1	6	PF00899	0.417
LIG_WRC_WIRS_1	33	38	PF05994	0.612
MOD_CK1_1	158	164	PF00069	0.380
MOD_CK1_1	31	37	PF00069	0.607
MOD_CK1_1	73	79	PF00069	0.702
MOD_CK2_1	2	8	PF00069	0.590
MOD_CK2_1	282	288	PF00069	0.380
MOD_CK2_1	86	92	PF00069	0.380
MOD_GlcNHglycan	255	258	PF01048	0.380
MOD_GlcNHglycan	326	329	PF01048	0.391
MOD_GlcNHglycan	61	64	PF01048	0.722
MOD_GSK3_1	28	35	PF00069	0.611
MOD_GSK3_1	59	66	PF00069	0.658
MOD_GSK3_1	71	78	PF00069	0.659
MOD_GSK3_1	82	89	PF00069	0.554
MOD_N-GLC_1	292	297	PF02516	0.480
MOD_N-GLC_1	63	68	PF02516	0.699
MOD_N-GLC_2	118	120	PF02516	0.380
MOD_N-GLC_2	330	332	PF02516	0.424
MOD_NEK2_1	103	108	PF00069	0.586
MOD_NEK2_1	210	215	PF00069	0.362
MOD_NEK2_1	348	353	PF00069	0.442
MOD_NEK2_1	72	77	PF00069	0.614
MOD_PIKK_1	103	109	PF00454	0.515
MOD_PIKK_1	292	298	PF00454	0.484
MOD_PK_1	200	206	PF00069	0.380
MOD_PKA_1	200	206	PF00069	0.380
MOD_PKA_2	200	206	PF00069	0.380
MOD_PKA_2	248	254	PF00069	0.380
MOD_PKA_2	37	43	PF00069	0.536
MOD_PKB_1	68	76	PF00069	0.690
MOD_Plk_1	155	161	PF00069	0.380
MOD_Plk_1	183	189	PF00069	0.380
MOD_Plk_2-3	237	243	PF00069	0.369
MOD_Plk_4	321	327	PF00069	0.394
MOD_ProDKin_1	232	238	PF00069	0.380
MOD_ProDKin_1	28	34	PF00069	0.686
TRG_DiLeu_BaEn_1	160	165	PF01217	0.380
TRG_DiLeu_BaEn_1	92	97	PF01217	0.515
TRG_ENDOCYTIC_2	127	130	PF00928	0.321
TRG_ENDOCYTIC_2	145	148	PF00928	0.359
TRG_ENDOCYTIC_2	192	195	PF00928	0.321
TRG_ENDOCYTIC_2	314	317	PF00928	0.423
TRG_ENDOCYTIC_2	338	341	PF00928	0.399
TRG_ENDOCYTIC_2	95	98	PF00928	0.515
TRG_ER_diArg_1	200	202	PF00400	0.380
TRG_ER_diArg_1	244	246	PF00400	0.369
TRG_NES_CRM1_1	346	362	PF08389	0.555

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7S7	Leptomonas seymouri	63%	100%
A0A0N0P7Y2	Leptomonas seymouri	36%	67%
A0A0N1HSR2	Leptomonas seymouri	49%	98%
A0A0N1I0V3	Leptomonas seymouri	56%	93%
A0A0N1IBK9	Leptomonas seymouri	46%	100%
A0A0N1ILH2	Leptomonas seymouri	31%	86%
A0A0N1P9X9	Leptomonas seymouri	44%	100%
A0A0N1PAV9	Leptomonas seymouri	79%	100%
A0A0N1PBN9	Leptomonas seymouri	42%	78%
A0A0N1PCC5	Leptomonas seymouri	44%	100%
A0A0N1PDK9	Leptomonas seymouri	46%	100%
A0A0S4IIW0	Bodo saltans	37%	92%
A0A0S4ILF8	Bodo saltans	46%	100%
A0A0S4IS15	Bodo saltans	37%	76%
A0A0S4J1J1	Bodo saltans	36%	94%
A0A0S4JDD1	Bodo saltans	39%	81%
A0A0S4JEU6	Bodo saltans	39%	77%
A0A0S4JJ52	Bodo saltans	64%	96%
A0A0S4JJ96	Bodo saltans	55%	100%
A0A0S4JJH3	Bodo saltans	55%	100%
A0A0S4JKZ6	Bodo saltans	39%	74%
A0A0S4KGD7	Bodo saltans	47%	100%
A0A0S4KKU2	Bodo saltans	43%	100%
A0A1X0NK88	Trypanosomatidae	66%	100%
A0A1X0NNN6	Trypanosomatidae	46%	100%
A0A1X0NS37	Trypanosomatidae	44%	100%
A0A1X0NS65	Trypanosomatidae	45%	100%
A0A1X0NUA6	Trypanosomatidae	44%	91%
A0A1X0NYR5	Trypanosomatidae	64%	100%
A0A1X0P6J3	Trypanosomatidae	38%	96%
A0A1X0P6Y9	Trypanosomatidae	43%	77%
A0A1X0P7H9	Trypanosomatidae	40%	82%
A0A1X0P7Q5	Trypanosomatidae	34%	94%
A0A1X0P982	Trypanosomatidae	49%	100%
A0A1X0P9R6	Trypanosomatidae	30%	81%
A0A1X0PA67	Trypanosomatidae	60%	100%
A0A1X0PAK9	Trypanosomatidae	59%	100%
A0A1X0PBJ2	Trypanosomatidae	42%	100%
A0A3Q8I8M6	Leishmania donovani	33%	84%
A0A3Q8ID20	Leishmania donovani	36%	76%
A0A3Q8IFB2	Leishmania donovani	60%	100%
A0A3Q8IH18	Leishmania donovani	46%	100%
A0A3Q8IHY7	Leishmania donovani	63%	100%
A0A3R7KQR6	Trypanosoma rangeli	42%	100%
A0A3R7M399	Trypanosoma rangeli	31%	84%
A0A3R7MBA3	Trypanosoma rangeli	40%	81%
A0A3R7MFZ7	Trypanosoma rangeli	49%	100%
A0A3R7MM48	Trypanosoma rangeli	43%	91%
A0A3R7N275	Trypanosoma rangeli	64%	100%
A0A3R7NP99	Trypanosoma rangeli	40%	100%
A0A3S5H6T9	Leishmania donovani	46%	98%
A0A3S5H7Q6	Leishmania donovani	97%	100%
A0A3S7WUR2	Leishmania donovani	43%	78%
A0A3S7WZ39	Leishmania donovani	46%	100%
A0A3S7X190	Leishmania donovani	63%	100%
A0A3S7X1Y0	Leishmania donovani	46%	100%
A0A3S7X7I6	Leishmania donovani	61%	100%
A0A3S7X7J8	Leishmania donovani	54%	100%
A0A3S7X7K2	Leishmania donovani	60%	100%
A0A3S7X8K6	Leishmania donovani	43%	100%
A0A3S7XAY3	Leishmania donovani	32%	90%
A0A422N8P1	Trypanosoma rangeli	59%	100%
A0A422N9D5	Trypanosoma rangeli	34%	93%
A0A422NKG0	Trypanosoma rangeli	44%	100%
A0A422NPG1	Trypanosoma rangeli	65%	100%
A0A422NWG6	Trypanosoma rangeli	37%	77%
A0A422NYN7	Trypanosoma rangeli	45%	100%
A0A422P483	Trypanosoma rangeli	35%	86%
A0C1E4	Paramecium tetraurelia	46%	100%
A0CCD2	Paramecium tetraurelia	46%	100%
A0CNL9	Paramecium tetraurelia	45%	100%
A0DJ90	Paramecium tetraurelia	46%	100%
A2X2G3	Oryza sativa subsp. indica	45%	100%
A2XN40	Oryza sativa subsp. indica	45%	100%
A2YEB4	Oryza sativa subsp. indica	45%	100%
A3C4N5	Oryza sativa subsp. japonica	46%	100%
A4H7D2	Leishmania braziliensis	34%	67%
A4H7Z3	Leishmania braziliensis	48%	98%
A4H9C0	Leishmania braziliensis	42%	78%
A4HAI7	Leishmania braziliensis	60%	100%
A4HAI8	Leishmania braziliensis	60%	100%
A4HAI9	Leishmania braziliensis	61%	100%
A4HAJ8	Leishmania braziliensis	54%	100%
A4HBE2	Leishmania braziliensis	43%	100%
A4HF98	Leishmania braziliensis	37%	67%
A4HGA9	Leishmania braziliensis	63%	100%
A4HGX0	Leishmania braziliensis	47%	100%
A4HJQ1	Leishmania braziliensis	87%	100%
A4HKU9	Leishmania braziliensis	46%	100%
A4HP65	Leishmania braziliensis	31%	91%
A4HVT0	Leishmania infantum	33%	84%
A4HWC1	Leishmania infantum	46%	98%
A4HXP1	Leishmania infantum	43%	78%
A4I1H6	Leishmania infantum	46%	100%
A4I2J0	Leishmania infantum	36%	76%
A4I3E3	Leishmania infantum	63%	100%
A4I400	Leishmania infantum	46%	100%
A4I768	Leishmania infantum	97%	100%
A4I8C8	Leishmania infantum	46%	100%
A4I9P2	Leishmania infantum	54%	100%
A4IAJ0	Leishmania infantum	43%	100%
A4IDH0	Leishmania infantum	32%	90%
A6H772	Bos taurus	48%	100%
A8WGP3	Danio rerio	47%	100%
A8XE00	Caenorhabditis briggsae	47%	100%
A9JRC7	Danio rerio	48%	100%
B0XUR7	Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163)	59%	68%
C9ZJZ6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	48%	100%
C9ZM48	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	31%	86%
C9ZMF3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	68%	100%
C9ZN02	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	100%
C9ZN06	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	56%	100%
C9ZWN3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	68%	100%
C9ZX13	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	85%
D0A019	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	77%
D0A358	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	93%
D0A805	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	63%	100%
D0A970	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	45%	100%
D0AAU4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	45%	100%
E9AHS8	Leishmania infantum	60%	100%
E9AHS9	Leishmania infantum	59%	100%
E9AHT0	Leishmania infantum	60%	100%
E9AHT1	Leishmania infantum	61%	100%
E9APH5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	84%
E9AQ21	Leishmania mexicana (strain MHOM/GT/2001/U1103)	46%	98%
E9ARF2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	43%	78%
E9ASX3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	33%	90%
E9AXL1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	46%	100%
E9AYN4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	73%
E9AZN0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	63%	100%
E9B090	Leishmania mexicana (strain MHOM/GT/2001/U1103)	46%	100%
E9B262	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
E9B387	Leishmania mexicana (strain MHOM/GT/2001/U1103)	46%	100%
E9B4P8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	60%	100%
E9B4P9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	60%	100%
E9B4Q0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	61%	100%
E9B4Q1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	61%	100%
E9B4Q6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	54%	100%
E9B5L4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	44%	100%
G5EGK8	Caenorhabditis elegans	44%	100%
O02658	Caenorhabditis elegans	54%	100%
O04856	Nicotiana tabacum	65%	100%
O04857	Nicotiana tabacum	65%	100%
O04858	Nicotiana tabacum	64%	100%
O04860	Nicotiana tabacum	46%	100%
O04951	Arabidopsis thaliana	45%	100%
O15757	Dictyostelium discoideum	64%	100%
O43049	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	38%	77%
O74789	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	40%	100%
O76932	Drosophila melanogaster	46%	100%
O82733	Arabidopsis thaliana	68%	100%
O82734	Arabidopsis thaliana	63%	100%
P0C5D7	Oryza sativa subsp. indica	46%	100%
P11084	Oryctolagus cuniculus	48%	100%
P11493	Sus scrofa	46%	100%
P11611	Oryctolagus cuniculus	46%	100%
P11612	Drosophila melanogaster	58%	100%
P12982	Drosophila melanogaster	67%	100%
P13681	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	65%	100%
P16298	Homo sapiens	41%	70%
P20604	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	46%	100%
P20651	Rattus norvegicus	41%	70%
P20654	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	66%	100%
P22198	Zea mays	64%	100%
P23287	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	35%	66%
P23594	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	48%	99%
P23595	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	48%	97%
P23635	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	46%	100%
P23636	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	44%	100%
P23696	Drosophila melanogaster	46%	100%
P23733	Trypanosoma brucei brucei	67%	100%
P23734	Trypanosoma brucei brucei	68%	100%
P23778	Brassica napus	45%	100%
P23880	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	68%	100%
P30366	Arabidopsis thaliana	67%	100%
P32345	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	44%	100%
P32598	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	66%	100%
P32838	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	41%	99%
P32945	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	53%	66%
P34350	Caenorhabditis elegans	35%	97%
P36614	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	46%	100%
P36873	Homo sapiens	68%	100%
P36874	Xenopus laevis	68%	100%
P48452	Bos taurus	41%	70%
P48453	Mus musculus	41%	70%
P48454	Homo sapiens	41%	71%
P48455	Mus musculus	41%	71%
P48457	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	40%	66%
P48458	Caenorhabditis elegans	49%	100%
P48459	Caenorhabditis elegans	50%	80%
P48460	Caenorhabditis elegans	43%	80%
P48461	Drosophila melanogaster	67%	100%
P48462	Drosophila melanogaster	67%	100%
P48463	Gallus gallus	46%	100%
P48480	Acetabularia peniculus	66%	100%
P48481	Acetabularia peniculus	66%	100%
P48482	Arabidopsis thaliana	66%	100%
P48483	Arabidopsis thaliana	67%	100%
P48484	Arabidopsis thaliana	62%	100%
P48485	Arabidopsis thaliana	66%	100%
P48486	Arabidopsis thaliana	64%	100%
P48487	Brassica oleracea	67%	100%
P48488	Medicago sativa subsp. varia	65%	100%
P48489	Oryza sativa subsp. japonica	66%	100%
P48490	Phaseolus vulgaris	65%	100%
P48528	Arabidopsis thaliana	47%	100%
P48529	Arabidopsis thaliana	45%	100%
P48577	Acetabularia peniculus	46%	100%
P48578	Arabidopsis thaliana	45%	100%
P48579	Helianthus annuus	47%	100%
P48580	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	46%	100%
P48726	Paramecium tetraurelia	45%	100%
P48727	Caenorhabditis elegans	69%	100%
P49576	Paramecium tetraurelia	46%	100%
P53043	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	40%	71%
P60510	Homo sapiens	48%	100%
P61287	Bos taurus	68%	100%
P61292	Sus scrofa	68%	100%
P62136	Homo sapiens	68%	100%
P62137	Mus musculus	68%	100%
P62138	Rattus norvegicus	68%	100%
P62139	Oryctolagus cuniculus	68%	100%
P62140	Homo sapiens	68%	100%
P62141	Mus musculus	68%	100%
P62142	Rattus norvegicus	68%	100%
P62143	Oryctolagus cuniculus	68%	100%
P62207	Gallus gallus	68%	100%
P62714	Homo sapiens	46%	100%
P62715	Mus musculus	46%	100%
P62716	Rattus norvegicus	46%	100%
P63087	Mus musculus	68%	100%
P63088	Rattus norvegicus	68%	100%
P63328	Mus musculus	41%	70%
P63329	Rattus norvegicus	41%	70%
P63330	Mus musculus	46%	100%
P63331	Rattus norvegicus	46%	100%
P67774	Bos taurus	46%	100%
P67775	Homo sapiens	46%	100%
P67776	Sus scrofa	46%	100%
P67777	Oryctolagus cuniculus	46%	100%
P78968	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	58%	71%
P91420	Caenorhabditis elegans	53%	100%
P97470	Mus musculus	48%	100%
Q05547	Drosophila melanogaster	67%	100%
Q06009	Medicago sativa	46%	100%
Q07098	Arabidopsis thaliana	45%	100%
Q07099	Arabidopsis thaliana	44%	100%
Q07100	Arabidopsis thaliana	46%	100%
Q08209	Homo sapiens	41%	70%
Q0DBD3	Oryza sativa subsp. japonica	45%	100%
Q0E2S4	Oryza sativa subsp. japonica	45%	100%
Q0G819	Caenorhabditis elegans	43%	67%
Q0P594	Bos taurus	46%	100%
Q10298	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	41%	100%
Q10BT5	Oryza sativa subsp. japonica	45%	100%
Q27497	Caenorhabditis elegans	67%	100%
Q27884	Drosophila melanogaster	45%	100%
Q3SWW9	Bos taurus	68%	100%
Q3T0E7	Bos taurus	68%	100%
Q4Q1M5	Leishmania major	32%	100%
Q4Q2C2	Leishmania major	43%	100%
Q4Q3C0	Leishmania major	54%	100%
Q4Q3C5	Leishmania major	61%	100%
Q4Q3C6	Leishmania major	61%	100%
Q4Q3C7	Leishmania major	60%	100%
Q4Q3C8	Leishmania major	60%	100%
Q4Q4W8	Leishmania major	46%	100%
Q4Q7Z5	Leishmania major	45%	100%
Q4Q8K1	Leishmania major	63%	100%
Q4Q8T8	Leishmania major	37%	73%
Q4Q9W1	Leishmania major	46%	100%
Q4QE27	Leishmania major	42%	78%
Q4QFG0	Leishmania major	46%	98%
Q4QG03	Leishmania major	34%	84%
Q4WUR1	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	40%	68%
Q54RD6	Dictyostelium discoideum	44%	100%
Q59KY8	Candida albicans (strain SC5314 / ATCC MYA-2876)	45%	100%
Q5A6B6	Candida albicans (strain SC5314 / ATCC MYA-2876)	45%	88%
Q5BJ92	Rattus norvegicus	47%	100%
Q5I085	Xenopus tropicalis	68%	100%
Q5R6K8	Pongo abelii	48%	100%
Q5R740	Pongo abelii	68%	100%
Q61JR3	Caenorhabditis briggsae	67%	100%
Q627N3	Caenorhabditis briggsae	69%	100%
Q6BFF6	Paramecium tetraurelia	45%	100%
Q6CNT6	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	42%	100%
Q6FM81	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	45%	100%
Q6GQL2	Xenopus laevis	68%	100%
Q6IP91	Xenopus laevis	47%	100%
Q6NVU2	Xenopus tropicalis	68%	100%
Q6P861	Xenopus tropicalis	47%	100%
Q74ZR2	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	43%	100%
Q7SZ10	Xenopus laevis	68%	100%
Q84XU2	Arabidopsis thaliana	45%	68%
Q8LSN3	Pisum sativum	44%	100%
Q8MJ46	Canis lupus familiaris	67%	100%
Q8MJ47	Canis lupus familiaris	68%	100%
Q8WMS6	Canis lupus familiaris	68%	100%
Q8X178	Blumeria hordei	45%	100%
Q9FN02	Arabidopsis thaliana	31%	88%
Q9HFQ2	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	46%	100%
Q9LHE7	Arabidopsis thaliana	44%	100%
Q9M9W3	Arabidopsis thaliana	64%	100%
Q9NES8	Caenorhabditis elegans	43%	74%
Q9SX52	Arabidopsis thaliana	43%	100%
Q9U9A3	Dictyostelium discoideum	45%	100%
Q9UW86	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	66%	100%
Q9XGH7	Nicotiana tabacum	45%	100%
Q9XTT8	Caenorhabditis elegans	44%	100%
Q9XW79	Caenorhabditis elegans	46%	100%
Q9XZE5	Dictyostelium discoideum	45%	100%
Q9Y0B7	Dictyostelium discoideum	47%	100%
Q9ZSE4	Hevea brasiliensis	46%	100%
V5AUW3	Trypanosoma cruzi	50%	100%
V5B3V2	Trypanosoma cruzi	38%	96%
V5B5K9	Trypanosoma cruzi	43%	100%
V5B8G5	Trypanosoma cruzi	42%	100%
V5BBR3	Trypanosoma cruzi	34%	93%
V5BGM0	Trypanosoma cruzi	45%	92%
V5BKU4	Trypanosoma cruzi	64%	100%
V5BQD7	Trypanosoma cruzi	32%	84%
V5D2G9	Trypanosoma cruzi	65%	100%
V5D5S2	Trypanosoma cruzi	45%	77%
V5DCW3	Trypanosoma cruzi	43%	100%
V5DIG8	Trypanosoma cruzi	35%	84%
V5DMS5	Trypanosoma cruzi	40%	100%