3'-5' exonuclease domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q5Z1_LEIMA

TriTrypDb:

LmjF.31.2700 , LMJLV39_310037100 , LMJSD75_310037100

Length:

891

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	2
GO:0005737	cytoplasm	2	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	3
GO:0016020	membrane	2	1

Expansion

Sequence features

Q4Q5Z1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q5Z1

Function

Biological processes
Term	Name	Level	Count
GO:0000459	exonucleolytic trimming involved in rRNA processing	8	5
GO:0000467	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	9	5
GO:0000469	cleavage involved in rRNA processing	7	5
GO:0006139	nucleobase-containing compound metabolic process	3	5
GO:0006364	rRNA processing	8	5
GO:0006396	RNA processing	6	5
GO:0006725	cellular aromatic compound metabolic process	3	5
GO:0006807	nitrogen compound metabolic process	2	5
GO:0008152	metabolic process	1	5
GO:0009987	cellular process	1	5
GO:0016070	RNA metabolic process	5	5
GO:0016072	rRNA metabolic process	7	5
GO:0031123	RNA 3'-end processing	7	5
GO:0031125	rRNA 3'-end processing	9	5
GO:0034470	ncRNA processing	7	5
GO:0034641	cellular nitrogen compound metabolic process	3	5
GO:0034660	ncRNA metabolic process	6	5
GO:0043170	macromolecule metabolic process	3	5
GO:0043628	regulatory ncRNA 3'-end processing	8	5
GO:0044237	cellular metabolic process	2	5
GO:0044238	primary metabolic process	2	5
GO:0046483	heterocycle metabolic process	3	5
GO:0071704	organic substance metabolic process	2	5
GO:0090304	nucleic acid metabolic process	4	5
GO:0090305	nucleic acid phosphodiester bond hydrolysis	5	5
GO:0090501	RNA phosphodiester bond hydrolysis	6	5
GO:0090503	RNA phosphodiester bond hydrolysis, exonucleolytic	7	5
GO:1901360	organic cyclic compound metabolic process	3	5

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	10
GO:0003824	catalytic activity	1	8
GO:0004518	nuclease activity	4	8
GO:0004527	exonuclease activity	5	8
GO:0005488	binding	1	10
GO:0008408	3'-5' exonuclease activity	6	7
GO:0016787	hydrolase activity	2	8
GO:0016788	hydrolase activity, acting on ester bonds	3	8
GO:0097159	organic cyclic compound binding	2	10
GO:1901363	heterocyclic compound binding	2	10
GO:0000175	3'-5'-RNA exonuclease activity	7	5
GO:0004532	RNA exonuclease activity	5	5
GO:0004540	RNA nuclease activity	4	5
GO:0016796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	6	5
GO:0016896	RNA exonuclease activity, producing 5'-phosphomonoesters	6	5
GO:0140098	catalytic activity, acting on RNA	3	5
GO:0140640	catalytic activity, acting on a nucleic acid	2	5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	182	186	PF00656	0.426
CLV_C14_Caspase3-7	282	286	PF00656	0.538
CLV_NRD_NRD_1	149	151	PF00675	0.537
CLV_NRD_NRD_1	196	198	PF00675	0.467
CLV_NRD_NRD_1	4	6	PF00675	0.374
CLV_NRD_NRD_1	453	455	PF00675	0.469
CLV_NRD_NRD_1	487	489	PF00675	0.358
CLV_NRD_NRD_1	514	516	PF00675	0.471
CLV_NRD_NRD_1	655	657	PF00675	0.733
CLV_NRD_NRD_1	66	68	PF00675	0.564
CLV_NRD_NRD_1	661	663	PF00675	0.740
CLV_NRD_NRD_1	682	684	PF00675	0.526
CLV_NRD_NRD_1	72	74	PF00675	0.502
CLV_NRD_NRD_1	793	795	PF00675	0.545
CLV_PCSK_FUR_1	791	795	PF00082	0.485
CLV_PCSK_KEX2_1	149	151	PF00082	0.458
CLV_PCSK_KEX2_1	3	5	PF00082	0.377
CLV_PCSK_KEX2_1	453	455	PF00082	0.469
CLV_PCSK_KEX2_1	487	489	PF00082	0.505
CLV_PCSK_KEX2_1	514	516	PF00082	0.471
CLV_PCSK_KEX2_1	657	659	PF00082	0.717
CLV_PCSK_KEX2_1	661	663	PF00082	0.705
CLV_PCSK_KEX2_1	682	684	PF00082	0.487
CLV_PCSK_KEX2_1	72	74	PF00082	0.510
CLV_PCSK_KEX2_1	793	795	PF00082	0.544
CLV_PCSK_PC1ET2_1	657	659	PF00082	0.642
CLV_PCSK_SKI1_1	149	153	PF00082	0.414
CLV_PCSK_SKI1_1	213	217	PF00082	0.353
CLV_PCSK_SKI1_1	302	306	PF00082	0.450
CLV_PCSK_SKI1_1	487	491	PF00082	0.401
CLV_PCSK_SKI1_1	603	607	PF00082	0.320
CLV_PCSK_SKI1_1	72	76	PF00082	0.495
CLV_PCSK_SKI1_1	734	738	PF00082	0.414
CLV_PCSK_SKI1_1	764	768	PF00082	0.359
CLV_PCSK_SKI1_1	839	843	PF00082	0.382
DEG_APCC_DBOX_1	586	594	PF00400	0.431
DEG_APCC_DBOX_1	602	610	PF00400	0.254
DEG_APCC_DBOX_1	71	79	PF00400	0.467
DEG_APCC_DBOX_1	733	741	PF00400	0.428
DEG_APCC_KENBOX_2	462	466	PF00400	0.336
DEG_COP1_1	42	52	PF00400	0.471
DEG_MDM2_SWIB_1	39	47	PF02201	0.422
DEG_SCF_FBW7_2	568	575	PF00400	0.539
DOC_CDC14_PxL_1	779	787	PF14671	0.491
DOC_CKS1_1	408	413	PF01111	0.466
DOC_CKS1_1	569	574	PF01111	0.587
DOC_CKS1_1	640	645	PF01111	0.608
DOC_CYCLIN_RxL_1	833	846	PF00134	0.392
DOC_CYCLIN_yCln2_LP_2	109	115	PF00134	0.461
DOC_MAPK_gen_1	149	158	PF00069	0.387
DOC_MAPK_gen_1	164	174	PF00069	0.330
DOC_MAPK_gen_1	460	468	PF00069	0.438
DOC_MAPK_MEF2A_6	167	174	PF00069	0.516
DOC_MAPK_MEF2A_6	487	495	PF00069	0.377
DOC_PP1_RVXF_1	402	409	PF00149	0.407
DOC_PP2B_LxvP_1	47	50	PF13499	0.568
DOC_PP4_FxxP_1	459	462	PF00568	0.400
DOC_PP4_FxxP_1	528	531	PF00568	0.358
DOC_SPAK_OSR1_1	478	482	PF12202	0.329
DOC_USP7_MATH_1	193	197	PF00917	0.478
DOC_USP7_MATH_1	257	261	PF00917	0.295
DOC_USP7_MATH_1	281	285	PF00917	0.583
DOC_USP7_MATH_1	344	348	PF00917	0.657
DOC_USP7_MATH_1	629	633	PF00917	0.618
DOC_USP7_MATH_1	667	671	PF00917	0.632
DOC_USP7_MATH_1	795	799	PF00917	0.590
DOC_USP7_MATH_1	809	813	PF00917	0.700
DOC_WW_Pin1_4	243	248	PF00397	0.385
DOC_WW_Pin1_4	308	313	PF00397	0.582
DOC_WW_Pin1_4	407	412	PF00397	0.494
DOC_WW_Pin1_4	568	573	PF00397	0.714
DOC_WW_Pin1_4	639	644	PF00397	0.699
DOC_WW_Pin1_4	649	654	PF00397	0.718
DOC_WW_Pin1_4	804	809	PF00397	0.686
DOC_WW_Pin1_4	810	815	PF00397	0.706
DOC_WW_Pin1_4	881	886	PF00397	0.480
LIG_14-3-3_CanoR_1	128	133	PF00244	0.407
LIG_14-3-3_CanoR_1	682	686	PF00244	0.457
LIG_14-3-3_CanoR_1	793	801	PF00244	0.639
LIG_14-3-3_CanoR_1	865	871	PF00244	0.330
LIG_Actin_WH2_2	131	146	PF00022	0.350
LIG_AP2alpha_2	111	113	PF02296	0.458
LIG_APCC_ABBA_1	156	161	PF00400	0.415
LIG_APCC_ABBA_1	163	168	PF00400	0.429
LIG_APCC_ABBA_1	599	604	PF00400	0.357
LIG_BIR_III_4	745	749	PF00653	0.525
LIG_BRCT_BRCA1_1	269	273	PF00533	0.379
LIG_BRCT_BRCA1_1	32	36	PF00533	0.494
LIG_BRCT_BRCA1_1	506	510	PF00533	0.285
LIG_BRCT_BRCA1_1	831	835	PF00533	0.354
LIG_BRCT_BRCA1_2	506	512	PF00533	0.295
LIG_DLG_GKlike_1	208	215	PF00625	0.433
LIG_EH1_1	834	842	PF00400	0.429
LIG_FHA_1	138	144	PF00498	0.460
LIG_FHA_1	207	213	PF00498	0.516
LIG_FHA_1	286	292	PF00498	0.422
LIG_FHA_1	318	324	PF00498	0.537
LIG_FHA_1	42	48	PF00498	0.463
LIG_FHA_1	682	688	PF00498	0.494
LIG_FHA_1	78	84	PF00498	0.342
LIG_FHA_1	87	93	PF00498	0.274
LIG_FHA_2	198	204	PF00498	0.615
LIG_FHA_2	221	227	PF00498	0.400
LIG_FHA_2	280	286	PF00498	0.648
LIG_FHA_2	293	299	PF00498	0.379
LIG_FHA_2	351	357	PF00498	0.587
LIG_FHA_2	389	395	PF00498	0.531
LIG_FHA_2	784	790	PF00498	0.586
LIG_FHA_2	882	888	PF00498	0.457
LIG_LIR_Apic_2	457	462	PF02991	0.400
LIG_LIR_Apic_2	526	531	PF02991	0.351
LIG_LIR_Gen_1	22	32	PF02991	0.382
LIG_LIR_Gen_1	445	452	PF02991	0.424
LIG_LIR_Gen_1	499	505	PF02991	0.320
LIG_LIR_Gen_1	541	548	PF02991	0.434
LIG_LIR_Gen_1	595	601	PF02991	0.372
LIG_LIR_Gen_1	832	842	PF02991	0.340
LIG_LIR_Nem_3	117	123	PF02991	0.539
LIG_LIR_Nem_3	168	172	PF02991	0.326
LIG_LIR_Nem_3	22	27	PF02991	0.388
LIG_LIR_Nem_3	33	39	PF02991	0.357
LIG_LIR_Nem_3	445	450	PF02991	0.457
LIG_LIR_Nem_3	499	503	PF02991	0.325
LIG_LIR_Nem_3	541	546	PF02991	0.441
LIG_LIR_Nem_3	595	599	PF02991	0.371
LIG_LIR_Nem_3	695	700	PF02991	0.485
LIG_LIR_Nem_3	832	838	PF02991	0.342
LIG_LIR_Nem_3	9	15	PF02991	0.329
LIG_LYPXL_S_1	696	700	PF13949	0.384
LIG_LYPXL_yS_3	169	172	PF13949	0.441
LIG_PAM2_1	25	37	PF00658	0.325
LIG_Pex14_1	866	870	PF04695	0.325
LIG_Pex14_2	39	43	PF04695	0.407
LIG_Pex14_2	440	444	PF04695	0.377
LIG_Pex14_2	862	866	PF04695	0.331
LIG_Rb_LxCxE_1	295	314	PF01857	0.542
LIG_REV1ctd_RIR_1	697	706	PF16727	0.486
LIG_RPA_C_Fungi	666	678	PF08784	0.578
LIG_SH2_CRK	34	38	PF00017	0.397
LIG_SH2_CRK	372	376	PF00017	0.347
LIG_SH2_CRK	500	504	PF00017	0.310
LIG_SH2_GRB2like	372	375	PF00017	0.348
LIG_SH2_GRB2like	396	399	PF00017	0.461
LIG_SH2_NCK_1	372	376	PF00017	0.370
LIG_SH2_NCK_1	845	849	PF00017	0.444
LIG_SH2_SRC	372	375	PF00017	0.372
LIG_SH2_SRC	543	546	PF00017	0.433
LIG_SH2_SRC	561	564	PF00017	0.292
LIG_SH2_SRC	829	832	PF00017	0.469
LIG_SH2_STAP1	139	143	PF00017	0.376
LIG_SH2_STAP1	261	265	PF00017	0.421
LIG_SH2_STAP1	500	504	PF00017	0.310
LIG_SH2_STAP1	543	547	PF00017	0.475
LIG_SH2_STAT3	252	255	PF00017	0.344
LIG_SH2_STAT3	458	461	PF00017	0.349
LIG_SH2_STAT5	139	142	PF00017	0.374
LIG_SH2_STAT5	396	399	PF00017	0.366
LIG_SH2_STAT5	458	461	PF00017	0.349
LIG_SH2_STAT5	689	692	PF00017	0.414
LIG_SH2_STAT5	829	832	PF00017	0.483
LIG_SH3_3	109	115	PF00018	0.461
LIG_SH3_3	272	278	PF00018	0.397
LIG_SH3_3	374	380	PF00018	0.449
LIG_SH3_3	4	10	PF00018	0.369
LIG_SH3_3	637	643	PF00018	0.700
LIG_SUMO_SIM_anti_2	131	136	PF11976	0.423
LIG_SUMO_SIM_anti_2	176	182	PF11976	0.356
LIG_SUMO_SIM_anti_2	202	211	PF11976	0.447
LIG_SUMO_SIM_anti_2	501	507	PF11976	0.317
LIG_SUMO_SIM_anti_2	595	601	PF11976	0.439
LIG_SUMO_SIM_anti_2	776	784	PF11976	0.436
LIG_SUMO_SIM_par_1	179	185	PF11976	0.413
LIG_SUMO_SIM_par_1	501	507	PF11976	0.256
LIG_TRAF2_1	200	203	PF00917	0.673
LIG_TRAF2_1	560	563	PF00917	0.462
LIG_TYR_ITIM	32	37	PF00017	0.345
LIG_UBA3_1	532	538	PF00899	0.414
LIG_WRC_WIRS_1	609	614	PF05994	0.415
MOD_CDK_SPxK_1	568	574	PF00069	0.470
MOD_CDK_SPxxK_3	649	656	PF00069	0.603
MOD_CDK_SPxxK_3	804	811	PF00069	0.542
MOD_CK1_1	211	217	PF00069	0.548
MOD_CK1_1	220	226	PF00069	0.473
MOD_CK1_1	284	290	PF00069	0.661
MOD_CK1_1	311	317	PF00069	0.440
MOD_CK1_1	472	478	PF00069	0.359
MOD_CK1_1	496	502	PF00069	0.359
MOD_CK1_1	66	72	PF00069	0.616
MOD_CK1_1	762	768	PF00069	0.439
MOD_CK1_1	804	810	PF00069	0.733
MOD_CK1_1	822	828	PF00069	0.543
MOD_CK1_1	84	90	PF00069	0.227
MOD_CK1_1	846	852	PF00069	0.522
MOD_CK2_1	19	25	PF00069	0.351
MOD_CK2_1	197	203	PF00069	0.532
MOD_CK2_1	220	226	PF00069	0.460
MOD_CK2_1	292	298	PF00069	0.467
MOD_CK2_1	783	789	PF00069	0.580
MOD_CK2_1	794	800	PF00069	0.682
MOD_CK2_1	866	872	PF00069	0.451
MOD_GlcNHglycan	116	119	PF01048	0.594
MOD_GlcNHglycan	175	178	PF01048	0.441
MOD_GlcNHglycan	219	222	PF01048	0.435
MOD_GlcNHglycan	269	272	PF01048	0.581
MOD_GlcNHglycan	27	30	PF01048	0.549
MOD_GlcNHglycan	313	316	PF01048	0.562
MOD_GlcNHglycan	424	427	PF01048	0.529
MOD_GlcNHglycan	471	474	PF01048	0.428
MOD_GlcNHglycan	557	560	PF01048	0.418
MOD_GlcNHglycan	631	634	PF01048	0.696
MOD_GlcNHglycan	649	652	PF01048	0.616
MOD_GlcNHglycan	728	731	PF01048	0.566
MOD_GlcNHglycan	740	743	PF01048	0.618
MOD_GlcNHglycan	753	756	PF01048	0.682
MOD_GlcNHglycan	849	852	PF01048	0.500
MOD_GSK3_1	193	200	PF00069	0.513
MOD_GSK3_1	202	209	PF00069	0.420
MOD_GSK3_1	281	288	PF00069	0.500
MOD_GSK3_1	384	391	PF00069	0.414
MOD_GSK3_1	489	496	PF00069	0.327
MOD_GSK3_1	647	654	PF00069	0.746
MOD_GSK3_1	77	84	PF00069	0.293
MOD_GSK3_1	773	780	PF00069	0.433
MOD_GSK3_1	843	850	PF00069	0.444
MOD_LATS_1	195	201	PF00433	0.480
MOD_N-GLC_1	285	290	PF02516	0.485
MOD_N-GLC_1	342	347	PF02516	0.518
MOD_N-GLC_1	373	378	PF02516	0.357
MOD_N-GLC_1	442	447	PF02516	0.382
MOD_N-GLC_1	751	756	PF02516	0.697
MOD_N-GLC_1	804	809	PF02516	0.705
MOD_N-GLC_2	217	219	PF02516	0.402
MOD_N-GLC_2	465	467	PF02516	0.325
MOD_NEK2_1	292	297	PF00069	0.376
MOD_NEK2_1	316	321	PF00069	0.605
MOD_NEK2_1	323	328	PF00069	0.770
MOD_NEK2_1	41	46	PF00069	0.356
MOD_NEK2_1	431	436	PF00069	0.400
MOD_NEK2_1	504	509	PF00069	0.324
MOD_NEK2_1	510	515	PF00069	0.397
MOD_NEK2_1	735	740	PF00069	0.475
MOD_NEK2_1	801	806	PF00069	0.758
MOD_PK_1	128	134	PF00069	0.387
MOD_PKA_1	197	203	PF00069	0.510
MOD_PKA_1	656	662	PF00069	0.620
MOD_PKA_2	349	355	PF00069	0.537
MOD_PKA_2	66	72	PF00069	0.520
MOD_PKA_2	681	687	PF00069	0.461
MOD_PKA_2	866	872	PF00069	0.398
MOD_PKB_1	664	672	PF00069	0.785
MOD_Plk_1	202	208	PF00069	0.441
MOD_Plk_1	257	263	PF00069	0.313
MOD_Plk_1	342	348	PF00069	0.547
MOD_Plk_1	373	379	PF00069	0.356
MOD_Plk_1	431	437	PF00069	0.411
MOD_Plk_1	442	448	PF00069	0.415
MOD_Plk_2-3	373	379	PF00069	0.356
MOD_Plk_4	19	25	PF00069	0.449
MOD_Plk_4	202	208	PF00069	0.635
MOD_Plk_4	472	478	PF00069	0.417
MOD_Plk_4	489	495	PF00069	0.302
MOD_Plk_4	595	601	PF00069	0.370
MOD_Plk_4	673	679	PF00069	0.574
MOD_Plk_4	692	698	PF00069	0.386
MOD_Plk_4	777	783	PF00069	0.388
MOD_Plk_4	86	92	PF00069	0.299
MOD_Plk_4	866	872	PF00069	0.375
MOD_ProDKin_1	243	249	PF00069	0.378
MOD_ProDKin_1	308	314	PF00069	0.593
MOD_ProDKin_1	407	413	PF00069	0.499
MOD_ProDKin_1	568	574	PF00069	0.718
MOD_ProDKin_1	639	645	PF00069	0.701
MOD_ProDKin_1	649	655	PF00069	0.718
MOD_ProDKin_1	804	810	PF00069	0.688
MOD_ProDKin_1	881	887	PF00069	0.476
MOD_SUMO_for_1	548	551	PF00179	0.366
MOD_SUMO_rev_2	161	165	PF00179	0.473
MOD_SUMO_rev_2	418	423	PF00179	0.513
MOD_SUMO_rev_2	797	804	PF00179	0.512
TRG_DiLeu_BaEn_1	202	207	PF01217	0.389
TRG_DiLeu_BaEn_1	774	779	PF01217	0.407
TRG_DiLeu_BaEn_3	680	686	PF01217	0.429
TRG_DiLeu_BaEn_4	419	425	PF01217	0.455
TRG_DiLeu_BaLyEn_6	141	146	PF01217	0.333
TRG_DiLeu_BaLyEn_6	70	75	PF01217	0.530
TRG_DiLeu_BaLyEn_6	836	841	PF01217	0.372
TRG_ENDOCYTIC_2	139	142	PF00928	0.426
TRG_ENDOCYTIC_2	169	172	PF00928	0.328
TRG_ENDOCYTIC_2	20	23	PF00928	0.520
TRG_ENDOCYTIC_2	34	37	PF00928	0.287
TRG_ENDOCYTIC_2	372	375	PF00928	0.348
TRG_ENDOCYTIC_2	447	450	PF00928	0.459
TRG_ENDOCYTIC_2	486	489	PF00928	0.399
TRG_ENDOCYTIC_2	500	503	PF00928	0.353
TRG_ENDOCYTIC_2	543	546	PF00928	0.433
TRG_ENDOCYTIC_2	620	623	PF00928	0.563
TRG_ENDOCYTIC_2	697	700	PF00928	0.435
TRG_ER_diArg_1	149	151	PF00400	0.384
TRG_ER_diArg_1	2	5	PF00400	0.421
TRG_ER_diArg_1	452	454	PF00400	0.457
TRG_ER_diArg_1	486	488	PF00400	0.496
TRG_ER_diArg_1	514	516	PF00400	0.432
TRG_ER_diArg_1	586	589	PF00400	0.437
TRG_ER_diArg_1	661	664	PF00400	0.633
TRG_ER_diArg_1	71	73	PF00400	0.560
TRG_ER_diArg_1	791	794	PF00400	0.477
TRG_NES_CRM1_1	173	185	PF08389	0.396
TRG_Pf-PMV_PEXEL_1	144	148	PF00026	0.282
TRG_Pf-PMV_PEXEL_1	225	230	PF00026	0.493
TRG_Pf-PMV_PEXEL_1	4	9	PF00026	0.379
TRG_Pf-PMV_PEXEL_1	514	518	PF00026	0.457
TRG_Pf-PMV_PEXEL_1	603	607	PF00026	0.499
TRG_Pf-PMV_PEXEL_1	839	843	PF00026	0.382

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IJE4	Leptomonas seymouri	53%	97%
A0A1X0NK05	Trypanosomatidae	35%	100%
A0A3Q8ISV5	Leishmania donovani	93%	100%
A0A422NPF9	Trypanosoma rangeli	36%	100%
A4HJQ7	Leishmania braziliensis	76%	98%
A4I774	Leishmania infantum	93%	100%
E9B268	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
V5D1X6	Trypanosoma cruzi	36%	100%