Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q5Y2_LEIMA

TriTrypDb:

LmjF.31.2780 , LMJLV39_310038300 , LMJSD75_310038300

Length:

237

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q5Y2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q5Y2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	47	49	PF00675	0.616
CLV_NRD_NRD_1	90	92	PF00675	0.562
CLV_PCSK_FUR_1	88	92	PF00082	0.715
CLV_PCSK_KEX2_1	47	49	PF00082	0.613
CLV_PCSK_KEX2_1	88	90	PF00082	0.552
DEG_APCC_KENBOX_2	225	229	PF00400	0.567
DEG_Nend_Nbox_1	1	3	PF02207	0.783
DOC_USP7_MATH_1	106	110	PF00917	0.700
DOC_USP7_MATH_1	123	127	PF00917	0.727
DOC_USP7_MATH_1	63	67	PF00917	0.680
DOC_USP7_UBL2_3	226	230	PF12436	0.706
DOC_WW_Pin1_4	112	117	PF00397	0.754
DOC_WW_Pin1_4	131	136	PF00397	0.607
DOC_WW_Pin1_4	165	170	PF00397	0.807
DOC_WW_Pin1_4	59	64	PF00397	0.614
LIG_14-3-3_CanoR_1	100	106	PF00244	0.656
LIG_14-3-3_CanoR_1	88	94	PF00244	0.561
LIG_FHA_1	195	201	PF00498	0.602
LIG_FHA_2	100	106	PF00498	0.751
LIG_FHA_2	125	131	PF00498	0.761
LIG_FHA_2	201	207	PF00498	0.649
LIG_FHA_2	8	14	PF00498	0.528
LIG_SH2_GRB2like	214	217	PF00017	0.604
LIG_SH2_SRC	214	217	PF00017	0.604
LIG_SH3_3	139	145	PF00018	0.793
LIG_SH3_3	34	40	PF00018	0.753
LIG_SH3_3	78	84	PF00018	0.611
LIG_TRAF2_1	10	13	PF00917	0.567
LIG_TRAF2_1	154	157	PF00917	0.788
LIG_TRAF2_1	170	173	PF00917	0.572
MOD_CAAXbox	234	237	PF01239	0.778
MOD_CDC14_SPxK_1	134	137	PF00782	0.719
MOD_CDK_SPxK_1	131	137	PF00069	0.722
MOD_CK1_1	194	200	PF00069	0.646
MOD_CK1_1	49	55	PF00069	0.706
MOD_CK1_1	59	65	PF00069	0.605
MOD_CK2_1	123	129	PF00069	0.809
MOD_CK2_1	182	188	PF00069	0.701
MOD_CK2_1	200	206	PF00069	0.801
MOD_CK2_1	63	69	PF00069	0.784
MOD_CK2_1	7	13	PF00069	0.541
MOD_CK2_1	99	105	PF00069	0.716
MOD_GlcNHglycan	146	149	PF01048	0.663
MOD_GlcNHglycan	193	196	PF01048	0.772
MOD_GSK3_1	12	19	PF00069	0.706
MOD_GSK3_1	161	168	PF00069	0.714
MOD_GSK3_1	189	196	PF00069	0.734
MOD_GSK3_1	46	53	PF00069	0.767
MOD_GSK3_1	59	66	PF00069	0.631
MOD_N-GLC_1	112	117	PF02516	0.736
MOD_N-GLC_1	56	61	PF02516	0.812
MOD_NEK2_1	189	194	PF00069	0.743
MOD_NEK2_1	2	7	PF00069	0.683
MOD_PIKK_1	182	188	PF00454	0.600
MOD_PIKK_1	50	56	PF00454	0.736
MOD_PKA_1	89	95	PF00069	0.573
MOD_PKA_2	46	52	PF00069	0.727
MOD_PKA_2	89	95	PF00069	0.573
MOD_PKA_2	99	105	PF00069	0.658
MOD_PKB_1	89	97	PF00069	0.733
MOD_Plk_1	12	18	PF00069	0.549
MOD_ProDKin_1	112	118	PF00069	0.754
MOD_ProDKin_1	131	137	PF00069	0.607
MOD_ProDKin_1	165	171	PF00069	0.807
MOD_ProDKin_1	59	65	PF00069	0.615
MOD_SUMO_rev_2	105	112	PF00179	0.601
TRG_ER_diArg_1	87	90	PF00400	0.544
TRG_Pf-PMV_PEXEL_1	91	96	PF00026	0.734

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X508	Leishmania donovani	79%	100%
A4HJR6	Leishmania braziliensis	34%	100%
A4I783	Leishmania infantum	80%	100%
E9B277	Leishmania mexicana (strain MHOM/GT/2001/U1103)	63%	73%