Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q5X9_LEIMA

TriTrypDb:

LmjF.31.2800 , LMJLV39_310038700 , LMJSD75_310038700

Length:

269

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q5X9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q5X9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	107	109	PF00675	0.525
CLV_NRD_NRD_1	135	137	PF00675	0.564
CLV_NRD_NRD_1	184	186	PF00675	0.567
CLV_PCSK_FUR_1	105	109	PF00082	0.586
CLV_PCSK_KEX2_1	107	109	PF00082	0.548
CLV_PCSK_KEX2_1	129	131	PF00082	0.510
CLV_PCSK_KEX2_1	183	185	PF00082	0.563
CLV_PCSK_PC1ET2_1	129	131	PF00082	0.510
CLV_PCSK_SKI1_1	107	111	PF00082	0.606
CLV_PCSK_SKI1_1	130	134	PF00082	0.543
CLV_PCSK_SKI1_1	234	238	PF00082	0.621
CLV_Separin_Metazoa	220	224	PF03568	0.661
DEG_Nend_UBRbox_4	1	3	PF02207	0.682
DOC_MAPK_gen_1	117	126	PF00069	0.572
DOC_MAPK_gen_1	155	163	PF00069	0.536
DOC_MAPK_gen_1	183	191	PF00069	0.621
DOC_MAPK_HePTP_8	114	126	PF00069	0.486
DOC_MAPK_MEF2A_6	117	126	PF00069	0.479
DOC_MAPK_MEF2A_6	155	163	PF00069	0.536
DOC_MAPK_RevD_3	170	185	PF00069	0.646
DOC_PP1_RVXF_1	185	192	PF00149	0.640
DOC_PP1_SILK_1	225	230	PF00149	0.657
DOC_USP7_MATH_1	109	113	PF00917	0.584
DOC_USP7_MATH_1	36	40	PF00917	0.586
DOC_USP7_UBL2_3	129	133	PF12436	0.501
DOC_WW_Pin1_4	171	176	PF00397	0.667
DOC_WW_Pin1_4	32	37	PF00397	0.647
LIG_14-3-3_CanoR_1	107	116	PF00244	0.686
LIG_14-3-3_CanoR_1	229	236	PF00244	0.662
LIG_14-3-3_CanoR_1	32	36	PF00244	0.732
LIG_APCC_ABBA_1	201	206	PF00400	0.735
LIG_FHA_2	32	38	PF00498	0.551
LIG_FHA_2	57	63	PF00498	0.702
LIG_IRF3_LxIS_1	159	164	PF10401	0.532
LIG_LIR_Gen_1	166	176	PF02991	0.686
LIG_LIR_Gen_1	76	85	PF02991	0.714
LIG_LIR_LC3C_4	206	210	PF02991	0.658
LIG_LIR_Nem_3	120	124	PF02991	0.579
LIG_LIR_Nem_3	166	172	PF02991	0.679
LIG_LIR_Nem_3	21	26	PF02991	0.510
LIG_PALB2_WD40_1	18	26	PF16756	0.507
LIG_Pex14_2	18	22	PF04695	0.693
LIG_SH2_PTP2	121	124	PF00017	0.565
LIG_SH2_STAT3	28	31	PF00017	0.512
LIG_SH2_STAT5	121	124	PF00017	0.565
LIG_SH2_STAT5	146	149	PF00017	0.656
LIG_SH3_3	216	222	PF00018	0.673
LIG_SUMO_SIM_anti_2	206	213	PF11976	0.601
LIG_SUMO_SIM_par_1	122	128	PF11976	0.452
LIG_SUMO_SIM_par_1	206	213	PF11976	0.622
LIG_TRAF2_1	140	143	PF00917	0.587
LIG_TRAF2_1	214	217	PF00917	0.736
LIG_TRAF2_1	96	99	PF00917	0.761
LIG_UBA3_1	227	234	PF00899	0.508
MOD_CDC14_SPxK_1	35	38	PF00782	0.609
MOD_CDK_SPxK_1	32	38	PF00069	0.605
MOD_CK1_1	145	151	PF00069	0.581
MOD_CK1_1	258	264	PF00069	0.651
MOD_CK1_1	39	45	PF00069	0.789
MOD_CK1_1	48	54	PF00069	0.675
MOD_CK1_1	73	79	PF00069	0.651
MOD_CK1_1	90	96	PF00069	0.728
MOD_CK1_1	97	103	PF00069	0.612
MOD_CK2_1	122	128	PF00069	0.608
MOD_CK2_1	171	177	PF00069	0.653
MOD_GlcNHglycan	223	226	PF01048	0.576
MOD_GlcNHglycan	260	263	PF01048	0.651
MOD_GlcNHglycan	45	48	PF01048	0.796
MOD_GlcNHglycan	89	92	PF01048	0.751
MOD_GSK3_1	142	149	PF00069	0.649
MOD_GSK3_1	32	39	PF00069	0.741
MOD_GSK3_1	48	55	PF00069	0.586
MOD_GSK3_1	71	78	PF00069	0.751
MOD_GSK3_1	90	97	PF00069	0.681
MOD_N-GLC_1	234	239	PF02516	0.562
MOD_N-GLC_1	4	9	PF02516	0.658
MOD_N-GLC_2	248	250	PF02516	0.654
MOD_NEK2_1	18	23	PF00069	0.556
MOD_NEK2_1	228	233	PF00069	0.573
MOD_NEK2_1	71	76	PF00069	0.672
MOD_PK_1	223	229	PF00069	0.658
MOD_PKA_1	107	113	PF00069	0.607
MOD_PKA_1	183	189	PF00069	0.570
MOD_PKA_2	107	113	PF00069	0.607
MOD_PKA_2	183	189	PF00069	0.570
MOD_PKA_2	228	234	PF00069	0.664
MOD_PKA_2	31	37	PF00069	0.693
MOD_PKB_1	105	113	PF00069	0.609
MOD_Plk_2-3	94	100	PF00069	0.695
MOD_Plk_4	109	115	PF00069	0.587
MOD_Plk_4	18	24	PF00069	0.621
MOD_Plk_4	223	229	PF00069	0.578
MOD_ProDKin_1	171	177	PF00069	0.669
MOD_ProDKin_1	32	38	PF00069	0.652
MOD_SUMO_rev_2	125	131	PF00179	0.601
TRG_DiLeu_BaEn_3	238	244	PF01217	0.718
TRG_DiLeu_BaEn_4	216	222	PF01217	0.659
TRG_ENDOCYTIC_2	121	124	PF00928	0.565
TRG_ENDOCYTIC_2	135	138	PF00928	0.564
TRG_ER_diArg_1	105	108	PF00400	0.587
TRG_ER_diArg_1	183	185	PF00400	0.573
TRG_NLS_MonoExtN_4	184	191	PF00514	0.640
TRG_Pf-PMV_PEXEL_1	130	134	PF00026	0.543
TRG_Pf-PMV_PEXEL_1	234	238	PF00026	0.621

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IJH6	Leptomonas seymouri	41%	100%
A0A3Q8IF41	Leishmania donovani	85%	100%
A4HJR8	Leishmania braziliensis	56%	100%
E9AHL9	Leishmania infantum	83%	100%
E9B279	Leishmania mexicana (strain MHOM/GT/2001/U1103)	78%	100%