Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q5W7_LEIMA

TriTrypDb:

LmjF.31.2910 , LMJLV39_310039900 , LMJSD75_310039900

Length:

247

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q5W7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q5W7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	126	130	PF00656	0.824
CLV_NRD_NRD_1	106	108	PF00675	0.616
CLV_NRD_NRD_1	214	216	PF00675	0.817
CLV_NRD_NRD_1	245	247	PF00675	0.801
CLV_NRD_NRD_1	91	93	PF00675	0.697
CLV_PCSK_KEX2_1	105	107	PF00082	0.621
CLV_PCSK_KEX2_1	214	216	PF00082	0.817
CLV_PCSK_KEX2_1	245	247	PF00082	0.801
CLV_PCSK_KEX2_1	91	93	PF00082	0.697
CLV_PCSK_SKI1_1	154	158	PF00082	0.581
CLV_PCSK_SKI1_1	42	46	PF00082	0.640
DEG_APCC_DBOX_1	41	49	PF00400	0.644
DEG_SCF_FBW7_1	142	149	PF00400	0.762
DEG_SPOP_SBC_1	184	188	PF00917	0.728
DOC_WW_Pin1_4	142	147	PF00397	0.748
DOC_WW_Pin1_4	170	175	PF00397	0.805
DOC_WW_Pin1_4	185	190	PF00397	0.638
DOC_WW_Pin1_4	4	9	PF00397	0.780
DOC_WW_Pin1_4	53	58	PF00397	0.739
LIG_14-3-3_CanoR_1	17	26	PF00244	0.655
LIG_14-3-3_CanoR_1	235	243	PF00244	0.591
LIG_14-3-3_CanoR_1	50	58	PF00244	0.638
LIG_14-3-3_CanoR_1	99	105	PF00244	0.625
LIG_14-3-3_CterR_2	245	247	PF00244	0.724
LIG_BRCT_BRCA1_1	65	69	PF00533	0.701
LIG_eIF4E_1	41	47	PF01652	0.640
LIG_FHA_1	155	161	PF00498	0.644
LIG_FHA_2	129	135	PF00498	0.614
LIG_FHA_2	88	94	PF00498	0.609
LIG_GBD_Chelix_1	152	160	PF00786	0.583
LIG_MYND_1	142	146	PF01753	0.763
LIG_SH2_STAT5	51	54	PF00017	0.686
LIG_SH3_2	210	215	PF14604	0.819
LIG_SH3_3	207	213	PF00018	0.663
LIG_SUMO_SIM_par_1	180	188	PF11976	0.727
MOD_CDK_SPK_2	142	147	PF00069	0.765
MOD_CDK_SPK_2	170	175	PF00069	0.690
MOD_CDK_SPxK_1	4	10	PF00069	0.777
MOD_CK1_1	170	176	PF00069	0.779
MOD_CK1_1	228	234	PF00069	0.826
MOD_CK1_1	33	39	PF00069	0.660
MOD_CK1_1	56	62	PF00069	0.788
MOD_CK1_1	67	73	PF00069	0.713
MOD_CK2_1	67	73	PF00069	0.772
MOD_CK2_1	87	93	PF00069	0.600
MOD_Cter_Amidation	243	246	PF01082	0.806
MOD_GlcNHglycan	115	118	PF01048	0.703
MOD_GlcNHglycan	165	168	PF01048	0.736
MOD_GlcNHglycan	169	172	PF01048	0.745
MOD_GlcNHglycan	19	22	PF01048	0.636
MOD_GlcNHglycan	66	69	PF01048	0.624
MOD_GSK3_1	142	149	PF00069	0.765
MOD_GSK3_1	154	161	PF00069	0.549
MOD_GSK3_1	163	170	PF00069	0.722
MOD_GSK3_1	180	187	PF00069	0.530
MOD_GSK3_1	52	59	PF00069	0.573
MOD_GSK3_1	63	70	PF00069	0.633
MOD_N-GLC_1	184	189	PF02516	0.728
MOD_NEK2_1	163	168	PF00069	0.774
MOD_NEK2_1	52	57	PF00069	0.536
MOD_NEK2_1	84	89	PF00069	0.623
MOD_NEK2_2	100	105	PF00069	0.764
MOD_PIKK_1	236	242	PF00454	0.729
MOD_PKA_2	108	114	PF00069	0.775
MOD_PKA_2	30	36	PF00069	0.667
MOD_Plk_1	158	164	PF00069	0.693
MOD_ProDKin_1	142	148	PF00069	0.747
MOD_ProDKin_1	170	176	PF00069	0.806
MOD_ProDKin_1	185	191	PF00069	0.638
MOD_ProDKin_1	4	10	PF00069	0.777
MOD_ProDKin_1	53	59	PF00069	0.745
TRG_ER_diArg_1	104	107	PF00400	0.623
TRG_ER_diArg_1	213	215	PF00400	0.817
TRG_ER_diArg_1	217	220	PF00400	0.750
TRG_Pf-PMV_PEXEL_1	154	159	PF00026	0.581
TRG_Pf-PMV_PEXEL_1	235	240	PF00026	0.693

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IGF1	Leishmania donovani	94%	100%
A4HJT0	Leishmania braziliensis	74%	100%
A4I796	Leishmania infantum	94%	100%
E9B291	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%