Putative serine/threonine-protein kinase

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Repressor of differentiation kinase 2, putative

Species:

Leishmania major

UniProt:

Q4Q5W2_LEIMA

TriTrypDb:

LmjF.31.2960 , LMJLV39_310040500 , LMJSD75_310040500

Length:

441

Annotations

LeishMANIAdb annotations

A large and apprently artificial collection of diverse kinetoplastid protein kinases. None of them appear to be TM.

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 45

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	yes	yes: 7

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 7

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 60
NetGPI	no	yes: 0, no: 60

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q5W2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q5W2

Function

Biological processes
Term	Name	Level	Count
GO:0006468	protein phosphorylation	5	61
GO:0006793	phosphorus metabolic process	3	61
GO:0006796	phosphate-containing compound metabolic process	4	61
GO:0006807	nitrogen compound metabolic process	2	61
GO:0008152	metabolic process	1	61
GO:0009987	cellular process	1	61
GO:0016310	phosphorylation	5	61
GO:0019538	protein metabolic process	3	61
GO:0036211	protein modification process	4	61
GO:0043170	macromolecule metabolic process	3	61
GO:0043412	macromolecule modification	4	61
GO:0044237	cellular metabolic process	2	61
GO:0044238	primary metabolic process	2	61
GO:0071704	organic substance metabolic process	2	61
GO:1901564	organonitrogen compound metabolic process	3	61

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	61
GO:0003824	catalytic activity	1	61
GO:0004672	protein kinase activity	3	61
GO:0004674	protein serine/threonine kinase activity	4	48
GO:0005488	binding	1	61
GO:0005524	ATP binding	5	61
GO:0016301	kinase activity	4	61
GO:0016740	transferase activity	2	61
GO:0016772	transferase activity, transferring phosphorus-containing groups	3	61
GO:0016773	phosphotransferase activity, alcohol group as acceptor	4	61
GO:0017076	purine nucleotide binding	4	61
GO:0030554	adenyl nucleotide binding	5	61
GO:0032553	ribonucleotide binding	3	61
GO:0032555	purine ribonucleotide binding	4	61
GO:0032559	adenyl ribonucleotide binding	5	61
GO:0035639	purine ribonucleoside triphosphate binding	4	61
GO:0036094	small molecule binding	2	61
GO:0043167	ion binding	2	61
GO:0043168	anion binding	3	61
GO:0097159	organic cyclic compound binding	2	61
GO:0097367	carbohydrate derivative binding	2	61
GO:0140096	catalytic activity, acting on a protein	2	61
GO:1901265	nucleoside phosphate binding	3	61
GO:1901363	heterocyclic compound binding	2	61

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	119	123	PF00656	0.298
CLV_NRD_NRD_1	242	244	PF00675	0.353
CLV_NRD_NRD_1	6	8	PF00675	0.543
CLV_PCSK_KEX2_1	242	244	PF00082	0.319
CLV_PCSK_KEX2_1	308	310	PF00082	0.474
CLV_PCSK_KEX2_1	353	355	PF00082	0.418
CLV_PCSK_KEX2_1	45	47	PF00082	0.436
CLV_PCSK_PC1ET2_1	308	310	PF00082	0.475
CLV_PCSK_PC1ET2_1	353	355	PF00082	0.430
CLV_PCSK_PC1ET2_1	45	47	PF00082	0.441
CLV_PCSK_SKI1_1	128	132	PF00082	0.295
CLV_PCSK_SKI1_1	135	139	PF00082	0.302
CLV_PCSK_SKI1_1	167	171	PF00082	0.328
CLV_PCSK_SKI1_1	243	247	PF00082	0.351
CLV_PCSK_SKI1_1	327	331	PF00082	0.484
CLV_PCSK_SKI1_1	363	367	PF00082	0.409
CLV_PCSK_SKI1_1	45	49	PF00082	0.311
DEG_APCC_DBOX_1	300	308	PF00400	0.474
DEG_Nend_UBRbox_2	1	3	PF02207	0.555
DEG_SPOP_SBC_1	19	23	PF00917	0.767
DOC_CYCLIN_RxL_1	42	52	PF00134	0.285
DOC_MAPK_gen_1	131	139	PF00069	0.453
DOC_MAPK_gen_1	167	176	PF00069	0.331
DOC_MAPK_MEF2A_6	110	118	PF00069	0.317
DOC_MAPK_MEF2A_6	141	150	PF00069	0.276
DOC_PP2B_LxvP_1	16	19	PF13499	0.697
DOC_PP4_FxxP_1	295	298	PF00568	0.296
DOC_PP4_FxxP_1	421	424	PF00568	0.281
DOC_USP7_MATH_1	200	204	PF00917	0.340
DOC_WW_Pin1_4	205	210	PF00397	0.342
DOC_WW_Pin1_4	34	39	PF00397	0.636
LIG_14-3-3_CanoR_1	261	269	PF00244	0.389
LIG_14-3-3_CanoR_1	279	284	PF00244	0.330
LIG_14-3-3_CanoR_1	354	361	PF00244	0.399
LIG_Clathr_ClatBox_1	115	119	PF01394	0.308
LIG_Clathr_ClatBox_1	280	284	PF01394	0.327
LIG_Clathr_ClatBox_1	365	369	PF01394	0.272
LIG_eIF4E_1	42	48	PF01652	0.285
LIG_EVH1_1	16	20	PF00568	0.619
LIG_FHA_1	169	175	PF00498	0.343
LIG_FHA_1	176	182	PF00498	0.318
LIG_FHA_1	328	334	PF00498	0.499
LIG_FHA_1	62	68	PF00498	0.270
LIG_FHA_1	85	91	PF00498	0.328
LIG_FHA_2	288	294	PF00498	0.209
LIG_FHA_2	433	439	PF00498	0.332
LIG_GBD_Chelix_1	325	333	PF00786	0.436
LIG_LIR_Apic_2	208	214	PF02991	0.340
LIG_LIR_Apic_2	293	298	PF02991	0.322
LIG_LIR_Gen_1	144	155	PF02991	0.309
LIG_LIR_Nem_3	125	130	PF02991	0.299
LIG_LIR_Nem_3	144	150	PF02991	0.315
LIG_Pex14_2	295	299	PF04695	0.269
LIG_Pex14_2	53	57	PF04695	0.316
LIG_REV1ctd_RIR_1	137	145	PF16727	0.209
LIG_SH2_CRK	127	131	PF00017	0.289
LIG_SH2_SRC	120	123	PF00017	0.359
LIG_SH2_SRC	193	196	PF00017	0.328
LIG_SH2_STAP1	193	197	PF00017	0.308
LIG_SH2_STAP1	236	240	PF00017	0.318
LIG_SH2_STAP1	269	273	PF00017	0.394
LIG_SH2_STAP1	429	433	PF00017	0.393
LIG_SH2_STAT5	211	214	PF00017	0.336
LIG_SH2_STAT5	42	45	PF00017	0.275
LIG_SH3_3	14	20	PF00018	0.643
LIG_SUMO_SIM_par_1	113	119	PF11976	0.295
LIG_SUMO_SIM_par_1	279	284	PF11976	0.290
LIG_TRAF2_1	403	406	PF00917	0.543
LIG_TRAF2_1	435	438	PF00917	0.334
LIG_TRFH_1	210	214	PF08558	0.332
LIG_WRC_WIRS_1	365	370	PF05994	0.288
MOD_CK1_1	223	229	PF00069	0.316
MOD_CK1_1	267	273	PF00069	0.326
MOD_CK1_1	332	338	PF00069	0.547
MOD_CK1_1	52	58	PF00069	0.307
MOD_CK2_1	18	24	PF00069	0.527
MOD_CK2_1	287	293	PF00069	0.358
MOD_CK2_1	299	305	PF00069	0.450
MOD_CK2_1	364	370	PF00069	0.344
MOD_CK2_1	432	438	PF00069	0.325
MOD_GlcNHglycan	269	272	PF01048	0.359
MOD_GlcNHglycan	377	381	PF01048	0.669
MOD_GlcNHglycan	54	57	PF01048	0.343
MOD_GlcNHglycan	60	64	PF01048	0.460
MOD_GSK3_1	18	25	PF00069	0.703
MOD_GSK3_1	201	208	PF00069	0.337
MOD_GSK3_1	260	267	PF00069	0.380
MOD_GSK3_1	299	306	PF00069	0.441
MOD_N-GLC_1	76	81	PF02516	0.220
MOD_N-GLC_2	256	258	PF02516	0.209
MOD_NEK2_1	175	180	PF00069	0.330
MOD_NEK2_1	187	192	PF00069	0.304
MOD_NEK2_1	299	304	PF00069	0.426
MOD_NEK2_1	348	353	PF00069	0.519
MOD_NEK2_2	269	274	PF00069	0.243
MOD_PIKK_1	327	333	PF00454	0.522
MOD_PIKK_1	422	428	PF00454	0.439
MOD_PK_1	279	285	PF00069	0.457
MOD_PK_1	371	377	PF00069	0.308
MOD_PKA_1	353	359	PF00069	0.398
MOD_PKA_2	260	266	PF00069	0.365
MOD_PKA_2	287	293	PF00069	0.350
MOD_PKA_2	353	359	PF00069	0.411
MOD_Plk_1	193	199	PF00069	0.280
MOD_ProDKin_1	205	211	PF00069	0.342
MOD_ProDKin_1	34	40	PF00069	0.626
MOD_SUMO_rev_2	367	373	PF00179	0.514
TRG_DiLeu_BaEn_1	111	116	PF01217	0.350
TRG_DiLeu_BaLyEn_6	276	281	PF01217	0.427
TRG_DiLeu_BaLyEn_6	43	48	PF01217	0.209
TRG_DiLeu_LyEn_5	344	349	PF01217	0.397
TRG_ENDOCYTIC_2	127	130	PF00928	0.289
TRG_ENDOCYTIC_2	236	239	PF00928	0.331
TRG_ER_diArg_1	241	243	PF00400	0.400
TRG_Pf-PMV_PEXEL_1	279	284	PF00026	0.395
TRG_Pf-PMV_PEXEL_1	327	331	PF00026	0.487
TRG_Pf-PMV_PEXEL_1	46	50	PF00026	0.209

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P2D3	Leptomonas seymouri	28%	84%
A0A0N0P3N5	Leptomonas seymouri	42%	100%
A0A0N0P3Q8	Leptomonas seymouri	28%	100%
A0A0N0P953	Leptomonas seymouri	37%	92%
A0A0N1HVN6	Leptomonas seymouri	27%	100%
A0A0N1I9A0	Leptomonas seymouri	31%	68%
A0A0N1IHM7	Leptomonas seymouri	37%	75%
A0A0N1PD05	Leptomonas seymouri	37%	99%
A0A0N1PDW7	Leptomonas seymouri	30%	100%
A0A0N1PE80	Leptomonas seymouri	29%	78%
A0A0N1PEW4	Leptomonas seymouri	28%	72%
A0A0S4IMB7	Bodo saltans	40%	99%
A0A0S4IQ75	Bodo saltans	35%	88%
A0A0S4IRU8	Bodo saltans	27%	100%
A0A0S4IRZ7	Bodo saltans	33%	89%
A0A0S4IVW1	Bodo saltans	26%	70%
A0A0S4IX86	Bodo saltans	44%	100%
A0A0S4J4B3	Bodo saltans	27%	99%
A0A0S4J575	Bodo saltans	26%	71%
A0A0S4J6L4	Bodo saltans	28%	100%
A0A0S4JHA7	Bodo saltans	29%	96%
A0A0S4JI45	Bodo saltans	26%	68%
A0A0S4JIJ6	Bodo saltans	27%	78%
A0A0S4JIY0	Bodo saltans	29%	68%
A0A0S4JN19	Bodo saltans	28%	71%
A0A0S4JPZ1	Bodo saltans	65%	98%
A0A0S4KHR9	Bodo saltans	29%	100%
A0A0S4KN74	Bodo saltans	29%	100%
A0A1X0NIA0	Trypanosomatidae	44%	100%
A0A1X0NIX2	Trypanosomatidae	67%	100%
A0A1X0NNF5	Trypanosomatidae	35%	71%
A0A1X0NTL6	Trypanosomatidae	37%	94%
A0A1X0NUB2	Trypanosomatidae	28%	76%
A0A1X0P1A2	Trypanosomatidae	27%	95%
A0A1X0P4Z7	Trypanosomatidae	28%	79%
A0A1X0P527	Trypanosomatidae	39%	99%
A0A1X0P549	Trypanosomatidae	36%	93%
A0A1X0P5B1	Trypanosomatidae	26%	100%
A0A1X0P5F2	Trypanosomatidae	27%	100%
A0A1X0P863	Trypanosomatidae	33%	89%
A0A1X0P935	Trypanosomatidae	27%	100%
A0A1X0P994	Trypanosomatidae	32%	88%
A0A1X0P9C4	Trypanosomatidae	38%	88%
A0A3Q8IAQ1	Leishmania donovani	39%	100%
A0A3Q8IB30	Leishmania donovani	30%	100%
A0A3Q8IB74	Leishmania donovani	23%	100%
A0A3Q8IC87	Leishmania donovani	31%	100%
A0A3Q8IDK8	Leishmania donovani	28%	79%
A0A3Q8IEH3	Leishmania donovani	27%	100%
A0A3Q8IFK8	Leishmania donovani	99%	100%
A0A3Q8IFW0	Leishmania donovani	43%	100%
A0A3Q8IHH8	Leishmania donovani	38%	88%
A0A3Q8IIG1	Leishmania donovani	31%	100%
A0A3Q8IIH5	Leishmania donovani	38%	79%
A0A3Q8INQ4	Leishmania donovani	28%	100%
A0A3Q8INS5	Leishmania donovani	26%	100%
A0A3R7KCZ4	Trypanosoma rangeli	44%	100%
A0A3R7KMF0	Trypanosoma rangeli	29%	100%
A0A3R7KZ44	Trypanosoma rangeli	33%	75%
A0A3R7M848	Trypanosoma rangeli	29%	94%
A0A3R7MKG5	Trypanosoma rangeli	64%	100%
A0A3R7RIN5	Trypanosoma rangeli	38%	88%
A0A3S5H4Z4	Leishmania donovani	29%	83%
A0A3S5H5U5	Leishmania donovani	24%	100%
A0A3S5H606	Leishmania donovani	30%	100%
A0A3S5IRC3	Trypanosoma rangeli	30%	100%
A0A3S7WTN9	Leishmania donovani	27%	100%
A0A3S7WWE7	Leishmania donovani	22%	100%
A0A3S7WYP4	Leishmania donovani	26%	100%
A0A3S7X123	Leishmania donovani	26%	100%
A0A3S7X2W3	Leishmania donovani	26%	100%
A0A3S7X5M4	Leishmania donovani	31%	67%
A0A3S7X6T8	Leishmania donovani	38%	98%
A0A3S7X7D5	Leishmania donovani	27%	100%
A0A3S7X7Y2	Leishmania donovani	31%	100%
A0A3S7X8Z8	Leishmania donovani	25%	100%
A0A3S7X9S2	Leishmania donovani	30%	100%
A0A3S7XAL3	Leishmania donovani	38%	89%
A0A3S7XAT9	Leishmania donovani	36%	88%
A0A3S7XAX0	Leishmania donovani	40%	93%
A0A422NCP0	Trypanosoma rangeli	34%	89%
A0A422NH41	Trypanosoma rangeli	30%	77%
A0A422NT89	Trypanosoma rangeli	24%	67%
A0A422NUF0	Trypanosoma rangeli	39%	100%
A2BD05	Sus scrofa	33%	100%
A3B529	Oryza sativa subsp. japonica	29%	100%
A4H3C7	Leishmania braziliensis	29%	83%
A4H459	Leishmania braziliensis	26%	100%
A4H4S9	Leishmania braziliensis	24%	100%
A4H539	Leishmania braziliensis	30%	100%
A4H7W1	Leishmania braziliensis	36%	80%
A4H8C4	Leishmania braziliensis	28%	100%
A4H9L8	Leishmania braziliensis	31%	100%
A4HAC8	Leishmania braziliensis	27%	100%
A4HAS1	Leishmania braziliensis	29%	100%
A4HCD7	Leishmania braziliensis	29%	100%
A4HCE6	Leishmania braziliensis	40%	100%
A4HDU3	Leishmania braziliensis	25%	100%
A4HED7	Leishmania braziliensis	27%	100%
A4HG26	Leishmania braziliensis	25%	100%
A4HG27	Leishmania braziliensis	27%	81%
A4HG92	Leishmania braziliensis	27%	100%
A4HH03	Leishmania braziliensis	29%	100%
A4HHN1	Leishmania braziliensis	26%	100%
A4HHQ5	Leishmania braziliensis	39%	87%
A4HHS9	Leishmania braziliensis	24%	100%
A4HJT5	Leishmania braziliensis	93%	100%
A4HJW2	Leishmania braziliensis	43%	100%
A4HKG9	Leishmania braziliensis	26%	67%
A4HLR0	Leishmania braziliensis	37%	98%
A4HN71	Leishmania braziliensis	27%	100%
A4HNI1	Leishmania braziliensis	33%	92%
A4HP12	Leishmania braziliensis	34%	87%
A4HQG8	Leishmania braziliensis	29%	100%
A4HRM6	Leishmania infantum	29%	83%
A4HTB4	Leishmania infantum	30%	100%
A4HW88	Leishmania infantum	38%	79%
A4HWP5	Leishmania infantum	27%	100%
A4HXY2	Leishmania infantum	30%	100%
A4HZA2	Leishmania infantum	22%	100%
A4HZV1	Leishmania infantum	29%	100%
A4HZW8	Leishmania infantum	39%	100%
A4I140	Leishmania infantum	26%	100%
A4I1T4	Leishmania infantum	28%	100%
A4I1U3	Leishmania infantum	26%	100%
A4I349	Leishmania infantum	28%	78%
A4I3C6	Leishmania infantum	27%	100%
A4I435	Leishmania infantum	31%	100%
A4I4U6	Leishmania infantum	27%	100%
A4I4X0	Leishmania infantum	38%	88%
A4I7A1	Leishmania infantum	99%	100%
A4I7C4	Leishmania infantum	43%	100%
A4I7Z6	Leishmania infantum	31%	67%
A4I960	Leishmania infantum	38%	98%
A4I9H1	Leishmania infantum	27%	100%
A4I9Y5	Leishmania infantum	31%	100%
A4IB02	Leishmania infantum	25%	100%
A4IDC1	Leishmania infantum	34%	86%
A4IDC2	Leishmania infantum	36%	88%
A4IDK3	Leishmania infantum	40%	93%
B0LT89	Rattus norvegicus	29%	100%
C9ZIN1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	88%
C9ZKE1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	100%
C9ZLJ4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	100%
C9ZMH9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	63%	100%
C9ZUU2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	24%	67%
C9ZWI1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZWK2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	60%	100%
D0A2Z1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	33%	90%
D0A2Z6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	89%
D0AA64	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	29%	77%
D3ZBE5	Rattus norvegicus	36%	100%
E8NHS0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9ACA4	Leishmania major	29%	100%
E9ACW6	Leishmania major	26%	100%
E9ACW7	Leishmania major	28%	79%
E9AE77	Leishmania major	23%	100%
E9AFM1	Leishmania major	30%	100%
E9AG71	Leishmania infantum	24%	100%
E9AGS0	Leishmania infantum	24%	100%
E9AJJ2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	82%
E9AKB7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9AKZ7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9ALA7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9ALJ2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9APY9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	37%	79%
E9AQF3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9ARP5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9ARW9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	24%	100%
E9ASJ2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9ASS2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	87%
E9ASS3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	88%
E9AT06	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	92%
E9AUY2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	22%	100%
E9AVR5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	31%	100%
E9AVS7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
E9AX78	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9AXW8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9AZF5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9AZF6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	81%
E9AZL3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9B0C2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9B296	Leishmania mexicana (strain MHOM/GT/2001/U1103)	98%	100%
E9B2B7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	43%	100%
E9B2V8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	67%
E9B436	Leishmania mexicana (strain MHOM/GT/2001/U1103)	39%	98%
E9B4G9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9B4Z4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	100%
E9B5Y5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	100%
E9B745	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	92%
J9W0G9	Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487)	30%	77%
O01775	Caenorhabditis elegans	31%	100%
O14305	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	31%	94%
O22932	Arabidopsis thaliana	28%	100%
O22971	Arabidopsis thaliana	33%	88%
O60285	Homo sapiens	32%	67%
P06245	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	100%
P08458	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	90%
P11801	Homo sapiens	29%	100%
P22209	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	30%	100%
P28178	Dictyostelium discoideum	27%	92%
P28829	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	67%
P52497	Candida albicans	29%	71%
Q03428	Trypanosoma brucei brucei	40%	100%
Q08942	Trypanosoma brucei brucei	40%	100%
Q0V7M1	Bos taurus	29%	100%
Q10SC8	Oryza sativa subsp. japonica	28%	97%
Q27687	Leishmania major	30%	100%
Q2TA06	Bos taurus	27%	100%
Q4Q1J2	Leishmania major	39%	93%
Q4Q1S3	Leishmania major	36%	88%
Q4Q1S4	Leishmania major	35%	87%
Q4Q204	Leishmania major	28%	100%
Q4Q2Z2	Leishmania major	32%	100%
Q4Q3K6	Leishmania major	27%	100%
Q4Q3Y9	Leishmania major	38%	98%
Q4Q598	Leishmania major	31%	67%
Q4Q5T9	Leishmania major	43%	100%
Q4Q7W2	Leishmania major	31%	100%
Q4Q9I7	Leishmania major	28%	100%
Q4Q9K2	Leishmania major	27%	100%
Q4QA98	Leishmania major	26%	100%
Q4QBQ2	Leishmania major	40%	100%
Q4QBR6	Leishmania major	31%	100%
Q4QDK3	Leishmania major	24%	100%
Q4QF23	Leishmania major	26%	100%
Q4QFJ2	Leishmania major	38%	79%
Q4QIJ7	Leishmania major	30%	100%
Q4QJJ0	Leishmania major	24%	100%
Q501V0	Danio rerio	28%	100%
Q54QD5	Dictyostelium discoideum	30%	91%
Q5KQF5	Oryza sativa subsp. japonica	28%	98%
Q5QNM6	Oryza sativa subsp. japonica	29%	86%
Q5W736	Oryza sativa subsp. japonica	28%	96%
Q8C0Q4	Mus musculus	30%	70%
Q8TDX7	Homo sapiens	35%	100%
Q91YA2	Mus musculus	29%	100%
Q99KH8	Mus musculus	29%	100%
Q9ES70	Mus musculus	33%	100%
Q9ES74	Mus musculus	35%	100%
Q9FJ54	Arabidopsis thaliana	30%	100%
Q9FJ55	Arabidopsis thaliana	28%	91%
Q9GM70	Oryctolagus cuniculus	29%	100%
Q9LP51	Arabidopsis thaliana	30%	85%
Q9N2N1	Leishmania major	27%	100%
Q9NAH6	Caenorhabditis elegans	28%	80%
Q9SN43	Arabidopsis thaliana	28%	90%
Q9TXJ0	Caenorhabditis elegans	27%	100%
Q9Y077	Leishmania major	26%	100%
V5BC28	Trypanosoma cruzi	65%	88%
V5BCH2	Trypanosoma cruzi	28%	100%
V5BHW8	Trypanosoma cruzi	25%	70%
V5BKJ3	Trypanosoma cruzi	28%	100%
V5BPJ0	Trypanosoma cruzi	32%	89%
V5BPK4	Trypanosoma cruzi	31%	73%
V5BR65	Trypanosoma cruzi	41%	100%
V5BSA6	Trypanosoma cruzi	27%	67%
V5D579	Trypanosoma cruzi	44%	100%
V5DFW9	Trypanosoma cruzi	30%	76%
V5DQT5	Trypanosoma cruzi	29%	96%
V5DTI8	Trypanosoma cruzi	27%	100%
V5DUH0	Trypanosoma cruzi	27%	80%