Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q5S0_LEIMA

TriTrypDb:

LmjF.32.0160 , LMJLV39_320006600 , LMJSD75_320006700

Length:

386

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q5S0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q5S0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	19	23	PF00656	0.706
CLV_C14_Caspase3-7	214	218	PF00656	0.604
CLV_C14_Caspase3-7	275	279	PF00656	0.568
CLV_NRD_NRD_1	161	163	PF00675	0.809
CLV_NRD_NRD_1	199	201	PF00675	0.721
CLV_NRD_NRD_1	313	315	PF00675	0.692
CLV_NRD_NRD_1	350	352	PF00675	0.822
CLV_PCSK_FUR_1	197	201	PF00082	0.720
CLV_PCSK_KEX2_1	199	201	PF00082	0.721
CLV_PCSK_KEX2_1	313	315	PF00082	0.692
CLV_PCSK_KEX2_1	346	348	PF00082	0.821
CLV_PCSK_KEX2_1	368	370	PF00082	0.726
CLV_PCSK_KEX2_1	69	71	PF00082	0.688
CLV_PCSK_KEX2_1	75	77	PF00082	0.623
CLV_PCSK_KEX2_1	80	82	PF00082	0.614
CLV_PCSK_PC1ET2_1	346	348	PF00082	0.821
CLV_PCSK_PC1ET2_1	368	370	PF00082	0.726
CLV_PCSK_PC1ET2_1	69	71	PF00082	0.688
CLV_PCSK_PC1ET2_1	75	77	PF00082	0.623
CLV_PCSK_PC1ET2_1	80	82	PF00082	0.614
CLV_PCSK_PC7_1	76	82	PF00082	0.812
CLV_PCSK_SKI1_1	337	341	PF00082	0.732
CLV_PCSK_SKI1_1	66	70	PF00082	0.799
DEG_Nend_UBRbox_2	1	3	PF02207	0.736
DEG_SPOP_SBC_1	23	27	PF00917	0.667
DOC_ANK_TNKS_1	143	150	PF00023	0.748
DOC_MAPK_MEF2A_6	171	179	PF00069	0.722
DOC_PP4_FxxP_1	331	334	PF00568	0.786
DOC_USP7_MATH_1	138	142	PF00917	0.760
DOC_USP7_MATH_1	23	27	PF00917	0.743
DOC_USP7_MATH_1	277	281	PF00917	0.708
DOC_USP7_MATH_1	302	306	PF00917	0.723
DOC_USP7_MATH_1	339	343	PF00917	0.736
DOC_USP7_MATH_1	58	62	PF00917	0.572
DOC_USP7_MATH_1	83	87	PF00917	0.747
DOC_USP7_UBL2_3	163	167	PF12436	0.644
DOC_WW_Pin1_4	306	311	PF00397	0.824
DOC_WW_Pin1_4	56	61	PF00397	0.647
LIG_14-3-3_CanoR_1	101	110	PF00244	0.526
LIG_14-3-3_CanoR_1	183	193	PF00244	0.730
LIG_14-3-3_CanoR_1	84	88	PF00244	0.751
LIG_APCC_ABBA_1	193	198	PF00400	0.540
LIG_BRCT_BRCA1_1	64	68	PF00533	0.595
LIG_deltaCOP1_diTrp_1	267	273	PF00928	0.696
LIG_EVH1_2	124	128	PF00568	0.563
LIG_FHA_2	273	279	PF00498	0.563
LIG_LIR_Nem_3	2	7	PF02991	0.738
LIG_LIR_Nem_3	65	71	PF02991	0.665
LIG_MYND_1	60	64	PF01753	0.776
LIG_Pex14_1	269	273	PF04695	0.702
LIG_PTAP_UEV_1	17	22	PF05743	0.694
LIG_SH2_NCK_1	274	278	PF00017	0.776
LIG_SH2_STAT5	274	277	PF00017	0.771
LIG_SH2_STAT5	4	7	PF00017	0.741
LIG_SH3_2	64	69	PF14604	0.736
LIG_SH3_3	105	111	PF00018	0.741
LIG_SH3_3	11	17	PF00018	0.767
LIG_SH3_3	205	211	PF00018	0.757
LIG_SH3_3	54	60	PF00018	0.794
LIG_SH3_3	61	67	PF00018	0.701
LIG_SUMO_SIM_par_1	175	180	PF11976	0.792
LIG_TRAF2_1	10	13	PF00917	0.762
LIG_TRAF2_1	279	282	PF00917	0.651
LIG_WRC_WIRS_1	270	275	PF05994	0.638
LIG_WRC_WIRS_1	340	345	PF05994	0.811
LIG_WW_3	239	243	PF00397	0.704
MOD_CDK_SPxxK_3	306	313	PF00069	0.824
MOD_CK1_1	104	110	PF00069	0.564
MOD_CK1_1	169	175	PF00069	0.726
MOD_CK1_1	27	33	PF00069	0.783
MOD_CK1_1	272	278	PF00069	0.769
MOD_CK1_1	35	41	PF00069	0.679
MOD_CK1_1	364	370	PF00069	0.583
MOD_CK1_1	45	51	PF00069	0.537
MOD_CK2_1	155	161	PF00069	0.674
MOD_Cter_Amidation	73	76	PF01082	0.557
MOD_GlcNHglycan	103	106	PF01048	0.705
MOD_GlcNHglycan	139	143	PF01048	0.773
MOD_GlcNHglycan	171	174	PF01048	0.743
MOD_GlcNHglycan	18	21	PF01048	0.773
MOD_GlcNHglycan	213	216	PF01048	0.608
MOD_GlcNHglycan	251	254	PF01048	0.743
MOD_GlcNHglycan	29	32	PF01048	0.691
MOD_GlcNHglycan	293	296	PF01048	0.798
MOD_GlcNHglycan	304	307	PF01048	0.638
MOD_GlcNHglycan	326	329	PF01048	0.797
MOD_GlcNHglycan	378	381	PF01048	0.739
MOD_GlcNHglycan	383	386	PF01048	0.703
MOD_GlcNHglycan	46	50	PF01048	0.590
MOD_GlcNHglycan	52	55	PF01048	0.768
MOD_GSK3_1	110	117	PF00069	0.792
MOD_GSK3_1	23	30	PF00069	0.766
MOD_GSK3_1	268	275	PF00069	0.707
MOD_GSK3_1	291	298	PF00069	0.796
MOD_GSK3_1	302	309	PF00069	0.639
MOD_GSK3_1	320	327	PF00069	0.558
MOD_GSK3_1	35	42	PF00069	0.687
MOD_GSK3_1	357	364	PF00069	0.588
MOD_GSK3_1	374	381	PF00069	0.508
MOD_GSK3_1	58	65	PF00069	0.570
MOD_LATS_1	99	105	PF00433	0.746
MOD_N-GLC_1	222	227	PF02516	0.765
MOD_N-GLC_1	302	307	PF02516	0.770
MOD_NEK2_1	312	317	PF00069	0.830
MOD_NEK2_1	32	37	PF00069	0.578
MOD_NEK2_1	357	362	PF00069	0.600
MOD_NEK2_1	378	383	PF00069	0.576
MOD_NEK2_2	269	274	PF00069	0.752
MOD_PIKK_1	357	363	PF00454	0.845
MOD_PKA_2	244	250	PF00069	0.821
MOD_PKA_2	312	318	PF00069	0.828
MOD_PKA_2	35	41	PF00069	0.768
MOD_PKA_2	364	370	PF00069	0.773
MOD_PKA_2	83	89	PF00069	0.807
MOD_Plk_1	222	228	PF00069	0.719
MOD_Plk_4	123	129	PF00069	0.819
MOD_Plk_4	269	275	PF00069	0.755
MOD_Plk_4	295	301	PF00069	0.805
MOD_Plk_4	320	326	PF00069	0.811
MOD_ProDKin_1	306	312	PF00069	0.823
MOD_ProDKin_1	56	62	PF00069	0.645
MOD_SUMO_rev_2	158	165	PF00179	0.626
MOD_SUMO_rev_2	252	262	PF00179	0.688
MOD_SUMO_rev_2	341	348	PF00179	0.743
TRG_ER_diArg_1	189	192	PF00400	0.673
TRG_ER_diArg_1	312	314	PF00400	0.688
TRG_ER_diArg_1	33	36	PF00400	0.767
TRG_NLS_MonoExtN_4	66	73	PF00514	0.744

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8ICV9	Leishmania donovani	88%	100%
A4HJZ6	Leishmania braziliensis	64%	100%
A4I7H9	Leishmania infantum	88%	100%
E9B2D6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	83%	98%