LeishMANIAdb
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Ig-like domain-containing protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Ig-like domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q5Q8_LEIMA
TriTrypDb:
LmjF.32.0270 , LMJLV39_320007900 * , LMJSD75_320007900 *
Length:
1302

Annotations

LeishMANIAdb annotations

Receptor-like surface protein, evolutionarily mildly expanded in Kinetoplastids.. Localization: Cell surface (by feature)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 5
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 8
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 7, no: 2
NetGPI no yes: 0, no: 9
Cellular components
TermNameLevelCount
GO:0005737 cytoplasm 2 2
GO:0016020 membrane 2 9
GO:0110165 cellular anatomical entity 1 9
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Expansion

Sequence features

Q4Q5Q8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 1269 1273 PF00656 0.671
CLV_C14_Caspase3-7 781 785 PF00656 0.378
CLV_NRD_NRD_1 1044 1046 PF00675 0.574
CLV_NRD_NRD_1 390 392 PF00675 0.578
CLV_NRD_NRD_1 8 10 PF00675 0.610
CLV_PCSK_FUR_1 6 10 PF00082 0.515
CLV_PCSK_KEX2_1 1044 1046 PF00082 0.574
CLV_PCSK_KEX2_1 1175 1177 PF00082 0.334
CLV_PCSK_KEX2_1 1186 1188 PF00082 0.437
CLV_PCSK_KEX2_1 1254 1256 PF00082 0.459
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P870 Leptomonas seymouri 56% 98%
A0A1X0P6J8 Trypanosomatidae 35% 80%
A0A3Q8IF84 Leishmania donovani 91% 100%
A0A422P0Y6 Trypanosoma rangeli 34% 88%
A4HK08 Leishmania braziliensis 78% 100%
A4I7J1 Leishmania infantum 91% 100%
E9B2E8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 87% 100%
V5DTF6 Trypanosoma cruzi 35% 88%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS