Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q5P7_LEIMA

TriTrypDb:

LmjF.32.0380 , LMJLV39_320009000 , LMJSD75_320009000

Length:

437

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Cellular components
Term	Name	Level	Count
GO:0005815	microtubule organizing center	2	2
GO:0036064	ciliary basal body	3	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4Q5P7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q5P7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	298	302	PF00656	0.652
CLV_C14_Caspase3-7	430	434	PF00656	0.635
CLV_NRD_NRD_1	100	102	PF00675	0.463
CLV_NRD_NRD_1	128	130	PF00675	0.537
CLV_NRD_NRD_1	158	160	PF00675	0.705
CLV_NRD_NRD_1	379	381	PF00675	0.627
CLV_NRD_NRD_1	39	41	PF00675	0.488
CLV_NRD_NRD_1	392	394	PF00675	0.403
CLV_NRD_NRD_1	7	9	PF00675	0.609
CLV_NRD_NRD_1	71	73	PF00675	0.672
CLV_NRD_NRD_1	90	92	PF00675	0.674
CLV_PCSK_KEX2_1	100	102	PF00082	0.454
CLV_PCSK_KEX2_1	127	129	PF00082	0.533
CLV_PCSK_KEX2_1	196	198	PF00082	0.632
CLV_PCSK_KEX2_1	39	41	PF00082	0.490
CLV_PCSK_KEX2_1	392	394	PF00082	0.525
CLV_PCSK_KEX2_1	7	9	PF00082	0.609
CLV_PCSK_KEX2_1	71	73	PF00082	0.672
CLV_PCSK_KEX2_1	89	91	PF00082	0.682
CLV_PCSK_PC1ET2_1	196	198	PF00082	0.632
CLV_PCSK_PC7_1	124	130	PF00082	0.523
CLV_PCSK_PC7_1	35	41	PF00082	0.473
CLV_PCSK_SKI1_1	380	384	PF00082	0.609
CLV_PCSK_SKI1_1	42	46	PF00082	0.510
CLV_PCSK_SKI1_1	90	94	PF00082	0.525
CLV_Separin_Metazoa	68	72	PF03568	0.577
DEG_APCC_DBOX_1	41	49	PF00400	0.447
DOC_CKS1_1	152	157	PF01111	0.690
DOC_MAPK_gen_1	7	13	PF00069	0.600
DOC_PP2B_LxvP_1	199	202	PF13499	0.552
DOC_USP7_MATH_1	167	171	PF00917	0.647
DOC_USP7_MATH_1	281	285	PF00917	0.661
DOC_USP7_MATH_1	309	313	PF00917	0.669
DOC_USP7_MATH_1	329	333	PF00917	0.707
DOC_USP7_MATH_1	410	414	PF00917	0.621
DOC_WW_Pin1_4	151	156	PF00397	0.688
DOC_WW_Pin1_4	261	266	PF00397	0.651
DOC_WW_Pin1_4	271	276	PF00397	0.576
DOC_WW_Pin1_4	292	297	PF00397	0.666
DOC_WW_Pin1_4	372	377	PF00397	0.524
DOC_WW_Pin1_4	412	417	PF00397	0.640
DOC_WW_Pin1_4	421	426	PF00397	0.546
LIG_14-3-3_CanoR_1	134	139	PF00244	0.628
LIG_14-3-3_CanoR_1	219	228	PF00244	0.644
LIG_14-3-3_CanoR_1	364	373	PF00244	0.663
LIG_14-3-3_CanoR_1	39	49	PF00244	0.521
LIG_14-3-3_CanoR_1	408	416	PF00244	0.614
LIG_14-3-3_CanoR_1	59	63	PF00244	0.527
LIG_14-3-3_CanoR_1	72	78	PF00244	0.648
LIG_BRCT_BRCA1_1	359	363	PF00533	0.685
LIG_BRCT_BRCA1_1	374	378	PF00533	0.506
LIG_BRCT_BRCA1_1	416	420	PF00533	0.533
LIG_EVH1_1	199	203	PF00568	0.556
LIG_FHA_1	288	294	PF00498	0.566
LIG_FHA_1	383	389	PF00498	0.561
LIG_FHA_1	44	50	PF00498	0.465
LIG_FHA_2	296	302	PF00498	0.702
LIG_FHA_2	428	434	PF00498	0.621
LIG_LIR_Apic_2	186	190	PF02991	0.558
LIG_Pex14_1	250	254	PF04695	0.512
LIG_PTAP_UEV_1	415	420	PF05743	0.658
LIG_Rb_LxCxE_1	310	326	PF01857	0.642
LIG_SH2_STAT5	389	392	PF00017	0.526
LIG_SH2_STAT5	396	399	PF00017	0.449
LIG_SH3_1	197	203	PF00018	0.639
LIG_SH3_2	203	208	PF14604	0.633
LIG_SH3_3	161	167	PF00018	0.709
LIG_SH3_3	195	201	PF00018	0.672
LIG_SH3_3	266	272	PF00018	0.668
LIG_SH3_3	277	283	PF00018	0.616
LIG_SH3_3	322	328	PF00018	0.698
LIG_SH3_3	413	419	PF00018	0.644
LIG_SH3_3	8	14	PF00018	0.593
MOD_CDK_SPK_2	261	266	PF00069	0.651
MOD_CDK_SPK_2	372	377	PF00069	0.524
MOD_CDK_SPK_2	421	426	PF00069	0.630
MOD_CDK_SPxxK_3	421	428	PF00069	0.613
MOD_CK1_1	165	171	PF00069	0.682
MOD_CK1_1	261	267	PF00069	0.610
MOD_CK1_1	295	301	PF00069	0.687
MOD_CK1_1	333	339	PF00069	0.691
MOD_CK1_1	367	373	PF00069	0.652
MOD_CK1_1	412	418	PF00069	0.640
MOD_CK1_1	43	49	PF00069	0.536
MOD_CK1_1	61	67	PF00069	0.579
MOD_Cter_Amidation	378	381	PF01082	0.633
MOD_GlcNHglycan	142	145	PF01048	0.613
MOD_GlcNHglycan	238	241	PF01048	0.600
MOD_GlcNHglycan	303	306	PF01048	0.620
MOD_GlcNHglycan	332	335	PF01048	0.701
MOD_GlcNHglycan	366	369	PF01048	0.665
MOD_GlcNHglycan	401	405	PF01048	0.508
MOD_GlcNHglycan	416	419	PF01048	0.552
MOD_GlcNHglycan	42	45	PF01048	0.548
MOD_GSK3_1	288	295	PF00069	0.690
MOD_GSK3_1	329	336	PF00069	0.702
MOD_GSK3_1	358	365	PF00069	0.685
MOD_GSK3_1	367	374	PF00069	0.588
MOD_GSK3_1	410	417	PF00069	0.620
MOD_N-GLC_1	236	241	PF02516	0.607
MOD_NEK2_1	235	240	PF00069	0.587
MOD_NEK2_2	110	115	PF00069	0.544
MOD_PIKK_1	104	110	PF00454	0.468
MOD_PIKK_1	178	184	PF00454	0.692
MOD_PIKK_1	259	265	PF00454	0.655
MOD_PIKK_1	358	364	PF00454	0.557
MOD_PKA_1	127	133	PF00069	0.489
MOD_PKA_2	110	116	PF00069	0.566
MOD_PKA_2	127	133	PF00069	0.435
MOD_PKA_2	207	213	PF00069	0.674
MOD_PKA_2	427	433	PF00069	0.605
MOD_PKA_2	58	64	PF00069	0.635
MOD_PKA_2	73	79	PF00069	0.628
MOD_PKB_1	217	225	PF00069	0.614
MOD_Plk_1	309	315	PF00069	0.631
MOD_Plk_4	73	79	PF00069	0.679
MOD_ProDKin_1	151	157	PF00069	0.690
MOD_ProDKin_1	261	267	PF00069	0.652
MOD_ProDKin_1	271	277	PF00069	0.575
MOD_ProDKin_1	292	298	PF00069	0.667
MOD_ProDKin_1	372	378	PF00069	0.524
MOD_ProDKin_1	412	418	PF00069	0.640
MOD_ProDKin_1	421	427	PF00069	0.534
MOD_SUMO_for_1	183	186	PF00179	0.697
MOD_SUMO_for_1	192	195	PF00179	0.612
MOD_SUMO_for_1	307	310	PF00179	0.628
TRG_DiLeu_BaLyEn_6	289	294	PF01217	0.589
TRG_ER_diArg_1	127	129	PF00400	0.533
TRG_ER_diArg_1	39	41	PF00400	0.490
TRG_ER_diArg_1	392	395	PF00400	0.526
TRG_ER_diArg_1	6	8	PF00400	0.625
TRG_ER_diArg_1	70	72	PF00400	0.579
TRG_ER_diArg_1	89	91	PF00400	0.575
TRG_Pf-PMV_PEXEL_1	395	399	PF00026	0.390
TRG_Pf-PMV_PEXEL_1	91	96	PF00026	0.667

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HK18	Leishmania braziliensis	64%	83%
A4I7K2	Leishmania infantum	88%	83%
E9B2F9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	85%