LeishMANIAdb
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CX9C domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
CX9C domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q5M8_LEIMA
TriTrypDb:
LmjF.32.0550 , LMJLV39_320010900 , LMJSD75_320010900
Length:
113

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Cellular components
Term Name Level Count
GO:0016020 membrane 2 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

Q4Q5M8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q5M8

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 31 33 PF00675 0.453
CLV_NRD_NRD_1 82 84 PF00675 0.502
CLV_PCSK_SKI1_1 4 8 PF00082 0.555
DOC_MAPK_gen_1 50 59 PF00069 0.541
DOC_USP7_UBL2_3 100 104 PF12436 0.378
DOC_USP7_UBL2_3 29 33 PF12436 0.529
LIG_FHA_2 3 9 PF00498 0.538
LIG_LIR_Gen_1 5 15 PF02991 0.512
LIG_LIR_Nem_3 5 10 PF02991 0.550
LIG_LIR_Nem_3 96 101 PF02991 0.442
LIG_REV1ctd_RIR_1 96 104 PF16727 0.433
LIG_SH2_STAT5 101 104 PF00017 0.439
LIG_WRC_WIRS_1 103 108 PF05994 0.376
MOD_CK2_1 2 8 PF00069 0.423
MOD_GlcNHglycan 46 49 PF01048 0.518
MOD_GSK3_1 44 51 PF00069 0.480
MOD_NEK2_2 102 107 PF00069 0.345
MOD_NMyristoyl 1 7 PF02799 0.527
MOD_PIKK_1 93 99 PF00454 0.437
MOD_PK_1 16 22 PF00069 0.377
MOD_Plk_4 102 108 PF00069 0.371
MOD_SUMO_for_1 59 62 PF00179 0.508
MOD_SUMO_rev_2 8 17 PF00179 0.400
TRG_NLS_MonoExtC_3 31 37 PF00514 0.324
TRG_NLS_MonoExtN_4 29 36 PF00514 0.428

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P7N4 Leptomonas seymouri 65% 100%
A0A0S4JBG6 Bodo saltans 51% 100%
A0A1X0NUS0 Trypanosomatidae 51% 100%
A0A3S7X589 Leishmania donovani 93% 100%
A0A422NJZ3 Trypanosoma rangeli 50% 100%
A4HK36 Leishmania braziliensis 76% 100%
A4I7M7 Leishmania infantum 93% 100%
D0A9S2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 50% 100%
E9B2H8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 85% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS