LeishMANIAdb
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Putative serine/threonine protein kinase

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Putative serine/threonine protein kinase
Gene product:
Repressor of differentiation kinase 1, putative
Species:
Leishmania major
UniProt:
Q4Q5K1_LEIMA
TriTrypDb:
LmjF.32.0810 * , LMJLV39_320013800 * , LMJSD75_320013800 *
Length:
1368

Annotations

LeishMANIAdb annotations

This unusual receptor kinase contains at least 2TM segments (possibly even 4TM), an N-terminal sensor domain and 2 tandem protein kinase domains!. This kinase family is a result of expansive receptor evolution within kinetoplastids. Localization: Cell surface (by feature)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
Term Name Level Count
GO:0016020 membrane 2 6
GO:0110165 cellular anatomical entity 1 6

Expansion

Sequence features

Q4Q5K1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006468 protein phosphorylation 5 7
GO:0006793 phosphorus metabolic process 3 7
GO:0006796 phosphate-containing compound metabolic process 4 7
GO:0006807 nitrogen compound metabolic process 2 7
GO:0008152 metabolic process 1 7
GO:0009987 cellular process 1 7
GO:0016310 phosphorylation 5 7
GO:0019538 protein metabolic process 3 7
GO:0036211 protein modification process 4 7
GO:0043170 macromolecule metabolic process 3 7
GO:0043412 macromolecule modification 4 7
GO:0044237 cellular metabolic process 2 7
GO:0044238 primary metabolic process 2 7
GO:0071704 organic substance metabolic process 2 7
GO:1901564 organonitrogen compound metabolic process 3 7
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 7
GO:0003824 catalytic activity 1 7
GO:0004672 protein kinase activity 3 7
GO:0004674 protein serine/threonine kinase activity 4 6
GO:0005488 binding 1 7
GO:0005524 ATP binding 5 7
GO:0016301 kinase activity 4 7
GO:0016740 transferase activity 2 7
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 7
GO:0016773 phosphotransferase activity, alcohol group as acceptor 4 7
GO:0017076 purine nucleotide binding 4 7
GO:0030554 adenyl nucleotide binding 5 7
GO:0032553 ribonucleotide binding 3 7
GO:0032555 purine ribonucleotide binding 4 7
GO:0032559 adenyl ribonucleotide binding 5 7
GO:0035639 purine ribonucleoside triphosphate binding 4 7
GO:0036094 small molecule binding 2 7
GO:0043167 ion binding 2 7
GO:0043168 anion binding 3 7
GO:0097159 organic cyclic compound binding 2 7
GO:0097367 carbohydrate derivative binding 2 7
GO:0140096 catalytic activity, acting on a protein 2 7
GO:1901265 nucleoside phosphate binding 3 7
GO:1901363 heterocyclic compound binding 2 7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1187 1191 PF00656 0.526
CLV_C14_Caspase3-7 1306 1310 PF00656 0.526
CLV_C14_Caspase3-7 1334 1338 PF00656 0.530
CLV_C14_Caspase3-7 41 45 PF00656 0.695
CLV_C14_Caspase3-7 563 567 PF00656 0.345
CLV_C14_Caspase3-7 61 65 PF00656 0.508
CLV_C14_Caspase3-7 621 625 PF00656 0.441
CLV_NRD_NRD_1 1201 1203 PF00675 0.303
CLV_NRD_NRD_1 286 288 PF00675 0.430
CLV_NRD_NRD_1 398 400 PF00675 0.302
CLV_NRD_NRD_1 46 48 PF00675 0.414
CLV_NRD_NRD_1 628 630 PF00675 0.574
CLV_NRD_NRD_1 861 863 PF00675 0.351
CLV_PCSK_KEX2_1 1131 1133 PF00082 0.303
CLV_PCSK_KEX2_1 1201 1203 PF00082 0.303
CLV_PCSK_KEX2_1 1354 1356 PF00082 0.258
CLV_PCSK_KEX2_1 224 226 PF00082 0.339
CLV_PCSK_KEX2_1 286 288 PF00082 0.370
CLV_PCSK_KEX2_1 46 48 PF00082 0.414
CLV_PCSK_KEX2_1 548 550 PF00082 0.482
CLV_PCSK_KEX2_1 628 630 PF00082 0.574
CLV_PCSK_KEX2_1 859 861 PF00082 0.326
CLV_PCSK_PC1ET2_1 1131 1133 PF00082 0.303
CLV_PCSK_PC1ET2_1 1354 1356 PF00082 0.258
CLV_PCSK_PC1ET2_1 224 226 PF00082 0.339
CLV_PCSK_PC1ET2_1 548 550 PF00082 0.482
CLV_PCSK_PC1ET2_1 859 861 PF00082 0.326
CLV_PCSK_PC7_1 1197 1203 PF00082 0.274
CLV_PCSK_SKI1_1 1138 1142 PF00082 0.284
CLV_PCSK_SKI1_1 1202 1206 PF00082 0.274
CLV_PCSK_SKI1_1 3 7 PF00082 0.443
CLV_PCSK_SKI1_1 325 329 PF00082 0.308
CLV_PCSK_SKI1_1 350 354 PF00082 0.430
CLV_PCSK_SKI1_1 403 407 PF00082 0.277
CLV_PCSK_SKI1_1 411 415 PF00082 0.309
CLV_PCSK_SKI1_1 46 50 PF00082 0.422
CLV_PCSK_SKI1_1 545 549 PF00082 0.480
CLV_PCSK_SKI1_1 712 716 PF00082 0.537
CLV_PCSK_SKI1_1 751 755 PF00082 0.317
CLV_PCSK_SKI1_1 842 846 PF00082 0.368
CLV_PCSK_SKI1_1 995 999 PF00082 0.515
DEG_APCC_DBOX_1 1201 1209 PF00400 0.474
DEG_Nend_Nbox_1 1 3 PF02207 0.593
DEG_SCF_FBW7_1 1029 1035 PF00400 0.703
DEG_SCF_FBW7_1 974 981 PF00400 0.758
DEG_SPOP_SBC_1 1032 1036 PF00917 0.632
DEG_SPOP_SBC_1 380 384 PF00917 0.519
DEG_SPOP_SBC_1 688 692 PF00917 0.310
DEG_SPOP_SBC_1 773 777 PF00917 0.496
DEG_SPOP_SBC_1 79 83 PF00917 0.626
DEG_SPOP_SBC_1 916 920 PF00917 0.632
DOC_CDC14_PxL_1 1130 1138 PF14671 0.474
DOC_CKS1_1 1029 1034 PF01111 0.703
DOC_CKS1_1 436 441 PF01111 0.527
DOC_CYCLIN_yClb3_PxF_3 1022 1030 PF00134 0.703
DOC_CYCLIN_yCln2_LP_2 949 955 PF00134 0.665
DOC_MAPK_DCC_7 294 304 PF00069 0.569
DOC_MAPK_gen_1 1201 1207 PF00069 0.474
DOC_MAPK_gen_1 1258 1267 PF00069 0.474
DOC_MAPK_gen_1 399 406 PF00069 0.503
DOC_MAPK_gen_1 468 477 PF00069 0.551
DOC_MAPK_gen_1 490 499 PF00069 0.497
DOC_MAPK_gen_1 709 717 PF00069 0.304
DOC_MAPK_gen_1 746 754 PF00069 0.511
DOC_MAPK_gen_1 859 866 PF00069 0.530
DOC_MAPK_MEF2A_6 1224 1232 PF00069 0.474
DOC_MAPK_MEF2A_6 20 29 PF00069 0.643
DOC_MAPK_MEF2A_6 237 246 PF00069 0.491
DOC_MAPK_MEF2A_6 492 501 PF00069 0.495
DOC_MAPK_NFAT4_5 20 28 PF00069 0.644
DOC_MAPK_RevD_3 1117 1132 PF00069 0.474
DOC_PP1_RVXF_1 726 733 PF00149 0.326
DOC_PP1_RVXF_1 749 755 PF00149 0.516
DOC_PP1_RVXF_1 762 768 PF00149 0.488
DOC_PP4_FxxP_1 365 368 PF00568 0.514
DOC_USP7_MATH_1 1015 1019 PF00917 0.599
DOC_USP7_MATH_1 1108 1112 PF00917 0.474
DOC_USP7_MATH_1 1181 1185 PF00917 0.474
DOC_USP7_MATH_1 1276 1280 PF00917 0.474
DOC_USP7_MATH_1 131 135 PF00917 0.603
DOC_USP7_MATH_1 1344 1348 PF00917 0.498
DOC_USP7_MATH_1 15 19 PF00917 0.656
DOC_USP7_MATH_1 380 384 PF00917 0.518
DOC_USP7_MATH_1 745 749 PF00917 0.643
DOC_USP7_MATH_1 78 82 PF00917 0.613
DOC_USP7_MATH_1 784 788 PF00917 0.503
DOC_USP7_MATH_1 889 893 PF00917 0.686
DOC_USP7_MATH_1 917 921 PF00917 0.669
DOC_USP7_MATH_1 934 938 PF00917 0.654
DOC_USP7_MATH_1 954 958 PF00917 0.676
DOC_USP7_MATH_1 976 980 PF00917 0.746
DOC_USP7_MATH_1 987 991 PF00917 0.641
DOC_USP7_UBL2_3 838 842 PF12436 0.502
DOC_USP7_UBL2_3 859 863 PF12436 0.546
DOC_WW_Pin1_4 1028 1033 PF00397 0.765
DOC_WW_Pin1_4 1042 1047 PF00397 0.729
DOC_WW_Pin1_4 11 16 PF00397 0.731
DOC_WW_Pin1_4 1265 1270 PF00397 0.474
DOC_WW_Pin1_4 356 361 PF00397 0.531
DOC_WW_Pin1_4 435 440 PF00397 0.534
DOC_WW_Pin1_4 909 914 PF00397 0.589
DOC_WW_Pin1_4 927 932 PF00397 0.565
DOC_WW_Pin1_4 955 960 PF00397 0.654
DOC_WW_Pin1_4 970 975 PF00397 0.758
LIG_14-3-3_CanoR_1 1247 1254 PF00244 0.490
LIG_14-3-3_CanoR_1 225 231 PF00244 0.594
LIG_14-3-3_CanoR_1 294 300 PF00244 0.562
LIG_14-3-3_CanoR_1 962 966 PF00244 0.655
LIG_14-3-3_CanoR_1 991 997 PF00244 0.664
LIG_APCC_ABBA_1 302 307 PF00400 0.600
LIG_BIR_III_2 1309 1313 PF00653 0.481
LIG_BIR_III_2 888 892 PF00653 0.592
LIG_BIR_III_4 1079 1083 PF00653 0.644
LIG_BRCT_BRCA1_1 1110 1114 PF00533 0.474
LIG_BRCT_BRCA1_1 1362 1366 PF00533 0.474
LIG_BRCT_BRCA1_1 373 377 PF00533 0.523
LIG_BRCT_BRCA1_1 689 693 PF00533 0.310
LIG_BRCT_BRCA1_1 929 933 PF00533 0.532
LIG_Clathr_ClatBox_1 1229 1233 PF01394 0.474
LIG_Clathr_ClatBox_1 845 849 PF01394 0.581
LIG_EH1_1 521 529 PF00400 0.333
LIG_FHA_1 1306 1312 PF00498 0.526
LIG_FHA_1 187 193 PF00498 0.323
LIG_FHA_1 283 289 PF00498 0.643
LIG_FHA_1 347 353 PF00498 0.562
LIG_FHA_1 389 395 PF00498 0.506
LIG_FHA_1 408 414 PF00498 0.596
LIG_FHA_1 444 450 PF00498 0.537
LIG_FHA_1 462 468 PF00498 0.445
LIG_FHA_1 470 476 PF00498 0.474
LIG_FHA_1 521 527 PF00498 0.323
LIG_FHA_1 680 686 PF00498 0.386
LIG_FHA_1 775 781 PF00498 0.538
LIG_FHA_1 975 981 PF00498 0.706
LIG_FHA_2 1217 1223 PF00498 0.474
LIG_FHA_2 1355 1361 PF00498 0.476
LIG_FHA_2 226 232 PF00498 0.573
LIG_FHA_2 308 314 PF00498 0.579
LIG_FHA_2 326 332 PF00498 0.537
LIG_FHA_2 380 386 PF00498 0.521
LIG_FHA_2 806 812 PF00498 0.507
LIG_FHA_2 980 986 PF00498 0.704
LIG_Integrin_isoDGR_2 401 403 PF01839 0.303
LIG_Integrin_RGD_1 564 566 PF01839 0.539
LIG_IRF3_LxIS_1 1283 1289 PF10401 0.474
LIG_IRF3_LxIS_1 239 245 PF10401 0.467
LIG_LIR_Apic_2 1263 1269 PF02991 0.474
LIG_LIR_Gen_1 1111 1121 PF02991 0.526
LIG_LIR_Gen_1 1169 1180 PF02991 0.474
LIG_LIR_Gen_1 1289 1298 PF02991 0.502
LIG_LIR_Gen_1 1363 1368 PF02991 0.474
LIG_LIR_Gen_1 258 264 PF02991 0.487
LIG_LIR_Gen_1 361 371 PF02991 0.509
LIG_LIR_Gen_1 587 596 PF02991 0.306
LIG_LIR_Gen_1 643 654 PF02991 0.370
LIG_LIR_Gen_1 716 725 PF02991 0.299
LIG_LIR_Gen_1 874 885 PF02991 0.558
LIG_LIR_LC3C_4 525 529 PF02991 0.383
LIG_LIR_Nem_3 1111 1117 PF02991 0.474
LIG_LIR_Nem_3 1169 1175 PF02991 0.474
LIG_LIR_Nem_3 1190 1195 PF02991 0.526
LIG_LIR_Nem_3 1363 1367 PF02991 0.474
LIG_LIR_Nem_3 219 223 PF02991 0.506
LIG_LIR_Nem_3 258 262 PF02991 0.487
LIG_LIR_Nem_3 359 365 PF02991 0.512
LIG_LIR_Nem_3 539 544 PF02991 0.245
LIG_LIR_Nem_3 587 592 PF02991 0.305
LIG_LIR_Nem_3 643 649 PF02991 0.370
LIG_LIR_Nem_3 691 697 PF02991 0.318
LIG_LIR_Nem_3 716 721 PF02991 0.268
LIG_LIR_Nem_3 874 880 PF02991 0.549
LIG_LRP6_Inhibitor_1 218 224 PF00058 0.311
LIG_MLH1_MIPbox_1 690 694 PF16413 0.312
LIG_MYND_1 1022 1026 PF01753 0.701
LIG_MYND_3 299 303 PF01753 0.607
LIG_NRBOX 242 248 PF00104 0.500
LIG_PDZ_Class_2 1363 1368 PF00595 0.474
LIG_Pex14_2 160 164 PF04695 0.333
LIG_Pex14_2 365 369 PF04695 0.510
LIG_Pex14_2 510 514 PF04695 0.487
LIG_Pex14_2 693 697 PF04695 0.316
LIG_PTB_Apo_2 268 275 PF02174 0.539
LIG_PTB_Phospho_1 268 274 PF10480 0.531
LIG_SH2_CRK 718 722 PF00017 0.284
LIG_SH2_GRB2like 269 272 PF00017 0.522
LIG_SH2_GRB2like 362 365 PF00017 0.515
LIG_SH2_NCK_1 269 273 PF00017 0.546
LIG_SH2_PTP2 1266 1269 PF00017 0.474
LIG_SH2_PTP2 877 880 PF00017 0.543
LIG_SH2_SRC 42 45 PF00017 0.693
LIG_SH2_SRC 684 687 PF00017 0.379
LIG_SH2_STAP1 885 889 PF00017 0.563
LIG_SH2_STAP1 906 910 PF00017 0.593
LIG_SH2_STAT5 1118 1121 PF00017 0.503
LIG_SH2_STAT5 1163 1166 PF00017 0.491
LIG_SH2_STAT5 1172 1175 PF00017 0.520
LIG_SH2_STAT5 1213 1216 PF00017 0.474
LIG_SH2_STAT5 1266 1269 PF00017 0.474
LIG_SH2_STAT5 178 181 PF00017 0.318
LIG_SH2_STAT5 191 194 PF00017 0.338
LIG_SH2_STAT5 222 225 PF00017 0.488
LIG_SH2_STAT5 259 262 PF00017 0.483
LIG_SH2_STAT5 269 272 PF00017 0.538
LIG_SH2_STAT5 274 277 PF00017 0.609
LIG_SH2_STAT5 320 323 PF00017 0.526
LIG_SH2_STAT5 362 365 PF00017 0.516
LIG_SH2_STAT5 437 440 PF00017 0.563
LIG_SH2_STAT5 578 581 PF00017 0.289
LIG_SH2_STAT5 684 687 PF00017 0.364
LIG_SH2_STAT5 877 880 PF00017 0.543
LIG_SH3_3 1019 1025 PF00018 0.815
LIG_SH3_3 1026 1032 PF00018 0.766
LIG_SH3_3 112 118 PF00018 0.639
LIG_SH3_3 1327 1333 PF00018 0.495
LIG_SH3_3 150 156 PF00018 0.511
LIG_SH3_3 233 239 PF00018 0.552
LIG_SH3_3 308 314 PF00018 0.529
LIG_SH3_3 324 330 PF00018 0.506
LIG_SH3_3 339 345 PF00018 0.481
LIG_SH3_3 731 737 PF00018 0.339
LIG_SH3_3 795 801 PF00018 0.519
LIG_SH3_3 920 926 PF00018 0.678
LIG_SUMO_SIM_anti_2 1171 1178 PF11976 0.474
LIG_SUMO_SIM_anti_2 207 212 PF11976 0.245
LIG_SUMO_SIM_anti_2 245 251 PF11976 0.492
LIG_SUMO_SIM_anti_2 307 313 PF11976 0.523
LIG_SUMO_SIM_anti_2 389 396 PF11976 0.471
LIG_SUMO_SIM_anti_2 523 528 PF11976 0.318
LIG_SUMO_SIM_par_1 1328 1335 PF11976 0.472
LIG_SUMO_SIM_par_1 242 248 PF11976 0.489
LIG_SUMO_SIM_par_1 389 396 PF11976 0.544
LIG_SUMO_SIM_par_1 533 539 PF11976 0.313
LIG_SUMO_SIM_par_1 652 657 PF11976 0.314
LIG_SUMO_SIM_par_1 703 708 PF11976 0.292
LIG_SUMO_SIM_par_1 758 763 PF11976 0.478
LIG_TRAF2_1 1357 1360 PF00917 0.557
LIG_TRAF2_1 229 232 PF00917 0.641
LIG_UBA3_1 759 764 PF00899 0.324
LIG_WRC_WIRS_1 1361 1366 PF05994 0.310
LIG_WRC_WIRS_1 217 222 PF05994 0.398
LIG_WRC_WIRS_1 394 399 PF05994 0.413
LIG_WRC_WIRS_1 474 479 PF05994 0.360
LIG_WRC_WIRS_1 599 604 PF05994 0.368
MOD_CDK_SPxK_1 435 441 PF00069 0.390
MOD_CDK_SPxxK_3 955 962 PF00069 0.531
MOD_CK1_1 1060 1066 PF00069 0.437
MOD_CK1_1 1071 1077 PF00069 0.415
MOD_CK1_1 13 19 PF00069 0.538
MOD_CK1_1 1305 1311 PF00069 0.233
MOD_CK1_1 245 251 PF00069 0.354
MOD_CK1_1 355 361 PF00069 0.374
MOD_CK1_1 383 389 PF00069 0.378
MOD_CK1_1 422 428 PF00069 0.452
MOD_CK1_1 60 66 PF00069 0.497
MOD_CK1_1 613 619 PF00069 0.473
MOD_CK1_1 687 693 PF00069 0.362
MOD_CK1_1 805 811 PF00069 0.352
MOD_CK1_1 850 856 PF00069 0.378
MOD_CK1_1 871 877 PF00069 0.437
MOD_CK1_1 927 933 PF00069 0.390
MOD_CK1_1 970 976 PF00069 0.707
MOD_CK1_1 979 985 PF00069 0.674
MOD_CK1_1 990 996 PF00069 0.543
MOD_CK2_1 1286 1292 PF00069 0.310
MOD_CK2_1 1344 1350 PF00069 0.369
MOD_CK2_1 1354 1360 PF00069 0.265
MOD_CK2_1 136 142 PF00069 0.471
MOD_CK2_1 225 231 PF00069 0.433
MOD_CK2_1 307 313 PF00069 0.394
MOD_CK2_1 325 331 PF00069 0.400
MOD_CK2_1 383 389 PF00069 0.378
MOD_CK2_1 459 465 PF00069 0.438
MOD_CK2_1 555 561 PF00069 0.397
MOD_CK2_1 592 598 PF00069 0.355
MOD_CK2_1 805 811 PF00069 0.352
MOD_CK2_1 889 895 PF00069 0.499
MOD_CK2_1 916 922 PF00069 0.490
MOD_CK2_1 979 985 PF00069 0.634
MOD_Cter_Amidation 44 47 PF01082 0.601
MOD_GlcNHglycan 1017 1020 PF01048 0.677
MOD_GlcNHglycan 1076 1079 PF01048 0.449
MOD_GlcNHglycan 1110 1113 PF01048 0.310
MOD_GlcNHglycan 1242 1245 PF01048 0.310
MOD_GlcNHglycan 1278 1281 PF01048 0.310
MOD_GlcNHglycan 459 462 PF01048 0.356
MOD_GlcNHglycan 786 789 PF01048 0.399
MOD_GlcNHglycan 849 852 PF01048 0.390
MOD_GlcNHglycan 870 873 PF01048 0.431
MOD_GlcNHglycan 919 922 PF01048 0.578
MOD_GSK3_1 1028 1035 PF00069 0.635
MOD_GSK3_1 1037 1044 PF00069 0.642
MOD_GSK3_1 1053 1060 PF00069 0.677
MOD_GSK3_1 1067 1074 PF00069 0.323
MOD_GSK3_1 11 18 PF00069 0.618
MOD_GSK3_1 1108 1115 PF00069 0.383
MOD_GSK3_1 1144 1151 PF00069 0.340
MOD_GSK3_1 1162 1169 PF00069 0.328
MOD_GSK3_1 1236 1243 PF00069 0.310
MOD_GSK3_1 1278 1285 PF00069 0.306
MOD_GSK3_1 181 188 PF00069 0.332
MOD_GSK3_1 21 28 PF00069 0.532
MOD_GSK3_1 226 233 PF00069 0.469
MOD_GSK3_1 352 359 PF00069 0.409
MOD_GSK3_1 379 386 PF00069 0.384
MOD_GSK3_1 415 422 PF00069 0.489
MOD_GSK3_1 457 464 PF00069 0.356
MOD_GSK3_1 469 476 PF00069 0.346
MOD_GSK3_1 512 519 PF00069 0.331
MOD_GSK3_1 58 65 PF00069 0.489
MOD_GSK3_1 606 613 PF00069 0.422
MOD_GSK3_1 620 627 PF00069 0.517
MOD_GSK3_1 640 647 PF00069 0.359
MOD_GSK3_1 684 691 PF00069 0.372
MOD_GSK3_1 772 779 PF00069 0.346
MOD_GSK3_1 868 875 PF00069 0.557
MOD_GSK3_1 970 977 PF00069 0.685
MOD_N-GLC_1 1053 1058 PF02516 0.639
MOD_N-GLC_1 226 231 PF02516 0.511
MOD_N-GLC_1 282 287 PF02516 0.528
MOD_N-GLC_1 3 8 PF02516 0.578
MOD_N-GLC_1 305 310 PF02516 0.407
MOD_N-GLC_1 346 351 PF02516 0.478
MOD_N-GLC_1 356 361 PF02516 0.318
MOD_N-GLC_1 371 376 PF02516 0.346
MOD_N-GLC_1 419 424 PF02516 0.456
MOD_N-GLC_1 457 462 PF02516 0.350
MOD_N-GLC_1 486 491 PF02516 0.317
MOD_N-GLC_1 927 932 PF02516 0.388
MOD_NEK2_1 1068 1073 PF00069 0.394
MOD_NEK2_1 1214 1219 PF00069 0.310
MOD_NEK2_1 1260 1265 PF00069 0.389
MOD_NEK2_1 1286 1291 PF00069 0.342
MOD_NEK2_1 23 28 PF00069 0.601
MOD_NEK2_1 230 235 PF00069 0.541
MOD_NEK2_1 242 247 PF00069 0.306
MOD_NEK2_1 486 491 PF00069 0.334
MOD_NEK2_1 522 527 PF00069 0.353
MOD_NEK2_1 560 565 PF00069 0.425
MOD_NEK2_1 58 63 PF00069 0.525
MOD_NEK2_1 67 72 PF00069 0.473
MOD_NEK2_1 705 710 PF00069 0.337
MOD_NEK2_1 739 744 PF00069 0.310
MOD_NEK2_1 760 765 PF00069 0.324
MOD_NEK2_1 783 788 PF00069 0.355
MOD_NEK2_1 933 938 PF00069 0.524
MOD_NEK2_2 1102 1107 PF00069 0.381
MOD_NEK2_2 1181 1186 PF00069 0.310
MOD_NEK2_2 473 478 PF00069 0.338
MOD_PIKK_1 1166 1172 PF00454 0.310
MOD_PIKK_1 201 207 PF00454 0.310
MOD_PIKK_1 672 678 PF00454 0.404
MOD_PIKK_1 696 702 PF00454 0.355
MOD_PIKK_1 753 759 PF00454 0.426
MOD_PIKK_1 802 808 PF00454 0.489
MOD_PIKK_1 947 953 PF00454 0.650
MOD_PKA_1 1354 1360 PF00069 0.288
MOD_PKA_2 1246 1252 PF00069 0.397
MOD_PKA_2 1260 1266 PF00069 0.257
MOD_PKA_2 1354 1360 PF00069 0.310
MOD_PKA_2 277 283 PF00069 0.436
MOD_PKA_2 491 497 PF00069 0.280
MOD_PKA_2 555 561 PF00069 0.397
MOD_PKA_2 745 751 PF00069 0.428
MOD_PKA_2 961 967 PF00069 0.582
MOD_PKA_2 990 996 PF00069 0.567
MOD_Plk_1 1068 1074 PF00069 0.411
MOD_Plk_1 226 232 PF00069 0.518
MOD_Plk_1 3 9 PF00069 0.684
MOD_Plk_1 305 311 PF00069 0.469
MOD_Plk_1 325 331 PF00069 0.377
MOD_Plk_1 346 352 PF00069 0.492
MOD_Plk_1 388 394 PF00069 0.380
MOD_Plk_1 419 425 PF00069 0.455
MOD_Plk_1 592 598 PF00069 0.355
MOD_Plk_1 63 69 PF00069 0.499
MOD_Plk_1 644 650 PF00069 0.443
MOD_Plk_1 802 808 PF00069 0.339
MOD_Plk_2-3 136 142 PF00069 0.477
MOD_Plk_2-3 307 313 PF00069 0.380
MOD_Plk_2-3 459 465 PF00069 0.438
MOD_Plk_4 1057 1063 PF00069 0.487
MOD_Plk_4 1102 1108 PF00069 0.455
MOD_Plk_4 1168 1174 PF00069 0.310
MOD_Plk_4 136 142 PF00069 0.404
MOD_Plk_4 245 251 PF00069 0.335
MOD_Plk_4 307 313 PF00069 0.385
MOD_Plk_4 337 343 PF00069 0.413
MOD_Plk_4 358 364 PF00069 0.357
MOD_Plk_4 383 389 PF00069 0.401
MOD_Plk_4 390 396 PF00069 0.347
MOD_Plk_4 432 438 PF00069 0.417
MOD_Plk_4 522 528 PF00069 0.310
MOD_Plk_4 689 695 PF00069 0.366
MOD_Plk_4 814 820 PF00069 0.337
MOD_ProDKin_1 1028 1034 PF00069 0.718
MOD_ProDKin_1 1042 1048 PF00069 0.678
MOD_ProDKin_1 11 17 PF00069 0.667
MOD_ProDKin_1 1265 1271 PF00069 0.310
MOD_ProDKin_1 356 362 PF00069 0.390
MOD_ProDKin_1 435 441 PF00069 0.390
MOD_ProDKin_1 909 915 PF00069 0.472
MOD_ProDKin_1 927 933 PF00069 0.440
MOD_ProDKin_1 955 961 PF00069 0.565
MOD_ProDKin_1 970 976 PF00069 0.709
MOD_SUMO_for_1 1140 1143 PF00179 0.310
MOD_SUMO_rev_2 116 124 PF00179 0.436
MOD_SUMO_rev_2 1216 1225 PF00179 0.310
MOD_SUMO_rev_2 618 627 PF00179 0.520
MOD_SUMO_rev_2 834 844 PF00179 0.368
TRG_DiLeu_BaEn_1 390 395 PF01217 0.353
TRG_DiLeu_BaEn_1 546 551 PF01217 0.322
TRG_DiLeu_BaEn_2 1056 1062 PF01217 0.549
TRG_DiLeu_BaEn_2 597 603 PF01217 0.359
TRG_DiLeu_LyEn_5 546 551 PF01217 0.322
TRG_ENDOCYTIC_2 1118 1121 PF00928 0.310
TRG_ENDOCYTIC_2 1172 1175 PF00928 0.310
TRG_ENDOCYTIC_2 259 262 PF00928 0.323
TRG_ENDOCYTIC_2 320 323 PF00928 0.407
TRG_ENDOCYTIC_2 362 365 PF00928 0.373
TRG_ENDOCYTIC_2 718 721 PF00928 0.321
TRG_ENDOCYTIC_2 877 880 PF00928 0.407
TRG_ER_diArg_1 1200 1202 PF00400 0.351
TRG_ER_diArg_1 286 288 PF00400 0.445
TRG_ER_diArg_1 46 48 PF00400 0.507
TRG_ER_diArg_1 628 631 PF00400 0.452
TRG_ER_diArg_1 725 728 PF00400 0.396
TRG_NLS_MonoExtC_3 858 863 PF00514 0.409
TRG_Pf-PMV_PEXEL_1 1138 1142 PF00026 0.310
TRG_Pf-PMV_PEXEL_1 549 553 PF00026 0.334
TRG_Pf-PMV_PEXEL_1 583 587 PF00026 0.394
TRG_Pf-PMV_PEXEL_1 594 598 PF00026 0.296

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P7M0 Leptomonas seymouri 64% 89%
A0A3S7X5A9 Leishmania donovani 93% 100%
A4HK62 Leishmania braziliensis 81% 100%
A4I7P7 Leishmania infantum 95% 100%
E9B2K5 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS