UDENN domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q5J9_LEIMA

TriTrypDb:

LmjF.32.0830 , LMJLV39_320014000 , LMJSD75_320014000

Length:

466

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q5J9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q5J9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	373	377	PF00656	0.726
CLV_C14_Caspase3-7	400	404	PF00656	0.790
CLV_NRD_NRD_1	186	188	PF00675	0.445
CLV_NRD_NRD_1	191	193	PF00675	0.479
CLV_NRD_NRD_1	260	262	PF00675	0.563
CLV_PCSK_KEX2_1	185	187	PF00082	0.446
CLV_PCSK_KEX2_1	190	192	PF00082	0.477
CLV_PCSK_PC7_1	186	192	PF00082	0.467
CLV_PCSK_SKI1_1	113	117	PF00082	0.581
CLV_PCSK_SKI1_1	192	196	PF00082	0.627
CLV_PCSK_SKI1_1	450	454	PF00082	0.633
CLV_PCSK_SKI1_1	65	69	PF00082	0.593
DEG_APCC_DBOX_1	191	199	PF00400	0.592
DEG_ODPH_VHL_1	171	183	PF01847	0.503
DEG_SCF_FBW7_1	343	349	PF00400	0.727
DEG_SPOP_SBC_1	338	342	PF00917	0.602
DEG_SPOP_SBC_1	366	370	PF00917	0.760
DOC_CKS1_1	343	348	PF01111	0.733
DOC_CKS1_1	456	461	PF01111	0.644
DOC_CYCLIN_yCln2_LP_2	421	427	PF00134	0.586
DOC_MAPK_gen_1	175	183	PF00069	0.518
DOC_MAPK_gen_1	185	195	PF00069	0.480
DOC_MAPK_gen_1	275	283	PF00069	0.528
DOC_PP1_RVXF_1	122	129	PF00149	0.591
DOC_PP1_RVXF_1	278	284	PF00149	0.543
DOC_PP4_FxxP_1	150	153	PF00568	0.519
DOC_PP4_FxxP_1	456	459	PF00568	0.656
DOC_PP4_FxxP_1	75	78	PF00568	0.587
DOC_USP7_MATH_1	201	205	PF00917	0.663
DOC_USP7_MATH_1	210	214	PF00917	0.592
DOC_USP7_MATH_1	322	326	PF00917	0.702
DOC_USP7_MATH_1	337	341	PF00917	0.721
DOC_USP7_MATH_1	34	38	PF00917	0.742
DOC_USP7_MATH_1	351	355	PF00917	0.697
DOC_USP7_MATH_1	397	401	PF00917	0.740
DOC_USP7_MATH_1	434	438	PF00917	0.649
DOC_USP7_MATH_2	313	319	PF00917	0.753
DOC_WW_Pin1_4	163	168	PF00397	0.709
DOC_WW_Pin1_4	17	22	PF00397	0.800
DOC_WW_Pin1_4	176	181	PF00397	0.525
DOC_WW_Pin1_4	342	347	PF00397	0.788
DOC_WW_Pin1_4	390	395	PF00397	0.707
DOC_WW_Pin1_4	455	460	PF00397	0.731
DOC_WW_Pin1_4	5	10	PF00397	0.772
DOC_WW_Pin1_4	98	103	PF00397	0.610
LIG_14-3-3_CanoR_1	113	118	PF00244	0.581
LIG_14-3-3_CanoR_1	23	33	PF00244	0.741
LIG_14-3-3_CanoR_1	275	284	PF00244	0.607
LIG_14-3-3_CanoR_1	450	459	PF00244	0.644
LIG_14-3-3_CanoR_1	65	73	PF00244	0.572
LIG_APCC_ABBA_1	309	314	PF00400	0.613
LIG_BIR_II_1	1	5	PF00653	0.720
LIG_FHA_1	114	120	PF00498	0.575
LIG_FHA_1	42	48	PF00498	0.481
LIG_FHA_2	155	161	PF00498	0.539
LIG_FHA_2	343	349	PF00498	0.777
LIG_FHA_2	383	389	PF00498	0.821
LIG_FHA_2	391	397	PF00498	0.837
LIG_FHA_2	443	449	PF00498	0.620
LIG_LIR_Apic_2	148	153	PF02991	0.521
LIG_LIR_Apic_2	454	459	PF02991	0.653
LIG_LIR_Gen_1	291	298	PF02991	0.586
LIG_LIR_Gen_1	44	50	PF02991	0.470
LIG_LIR_Gen_1	91	102	PF02991	0.664
LIG_LIR_Nem_3	291	297	PF02991	0.641
LIG_LIR_Nem_3	446	452	PF02991	0.621
LIG_LIR_Nem_3	91	97	PF02991	0.652
LIG_LYPXL_yS_3	56	59	PF13949	0.640
LIG_NBox_RRM_1	317	327	PF00076	0.741
LIG_Pex14_1	46	50	PF04695	0.324
LIG_Pex14_2	283	287	PF04695	0.678
LIG_Pex14_2	449	453	PF04695	0.630
LIG_Pex14_2	90	94	PF04695	0.613
LIG_SH2_STAP1	367	371	PF00017	0.804
LIG_SH2_STAT3	146	149	PF00017	0.499
LIG_SH2_STAT5	132	135	PF00017	0.370
LIG_SH2_STAT5	220	223	PF00017	0.535
LIG_SH3_3	104	110	PF00018	0.477
LIG_SH3_3	114	120	PF00018	0.415
LIG_SH3_3	167	173	PF00018	0.607
LIG_SH3_3	195	201	PF00018	0.652
LIG_SH3_3	340	346	PF00018	0.786
LIG_SH3_3	94	100	PF00018	0.573
LIG_TRAF2_1	385	388	PF00917	0.776
LIG_WRC_WIRS_1	284	289	PF05994	0.552
LIG_WW_3	8	12	PF00397	0.603
MOD_CDC14_SPxK_1	20	23	PF00782	0.774
MOD_CDC14_SPxK_1	8	11	PF00782	0.602
MOD_CDK_SPxK_1	17	23	PF00069	0.773
MOD_CDK_SPxK_1	5	11	PF00069	0.604
MOD_CK1_1	2	8	PF00069	0.739
MOD_CK1_1	219	225	PF00069	0.636
MOD_CK1_1	22	28	PF00069	0.696
MOD_CK1_1	342	348	PF00069	0.692
MOD_CK1_1	354	360	PF00069	0.744
MOD_CK1_1	392	398	PF00069	0.773
MOD_CK1_1	399	405	PF00069	0.681
MOD_CK1_1	419	425	PF00069	0.667
MOD_CK2_1	219	225	PF00069	0.543
MOD_CK2_1	283	289	PF00069	0.552
MOD_CK2_1	382	388	PF00069	0.753
MOD_CK2_1	392	398	PF00069	0.683
MOD_GlcNHglycan	317	320	PF01048	0.702
MOD_GlcNHglycan	36	39	PF01048	0.666
MOD_GSK3_1	15	22	PF00069	0.756
MOD_GSK3_1	24	31	PF00069	0.687
MOD_GSK3_1	271	278	PF00069	0.618
MOD_GSK3_1	279	286	PF00069	0.660
MOD_GSK3_1	338	345	PF00069	0.771
MOD_GSK3_1	347	354	PF00069	0.666
MOD_GSK3_1	366	373	PF00069	0.515
MOD_GSK3_1	392	399	PF00069	0.668
MOD_GSK3_1	451	458	PF00069	0.626
MOD_GSK3_1	61	68	PF00069	0.583
MOD_NEK2_1	174	179	PF00069	0.466
MOD_NEK2_1	276	281	PF00069	0.633
MOD_NEK2_1	283	288	PF00069	0.577
MOD_NEK2_1	389	394	PF00069	0.803
MOD_NEK2_1	416	421	PF00069	0.689
MOD_PIKK_1	246	252	PF00454	0.650
MOD_PIKK_1	451	457	PF00454	0.642
MOD_PKA_2	22	28	PF00069	0.647
MOD_PKA_2	269	275	PF00069	0.599
MOD_PKA_2	276	282	PF00069	0.650
MOD_PKA_2	327	333	PF00069	0.688
MOD_Plk_4	216	222	PF00069	0.650
MOD_Plk_4	279	285	PF00069	0.744
MOD_Plk_4	322	328	PF00069	0.683
MOD_Plk_4	41	47	PF00069	0.504
MOD_ProDKin_1	163	169	PF00069	0.698
MOD_ProDKin_1	17	23	PF00069	0.801
MOD_ProDKin_1	176	182	PF00069	0.515
MOD_ProDKin_1	342	348	PF00069	0.790
MOD_ProDKin_1	390	396	PF00069	0.711
MOD_ProDKin_1	455	461	PF00069	0.733
MOD_ProDKin_1	5	11	PF00069	0.778
MOD_ProDKin_1	98	104	PF00069	0.605
MOD_SUMO_rev_2	460	466	PF00179	0.664
TRG_ENDOCYTIC_2	123	126	PF00928	0.483
TRG_ENDOCYTIC_2	56	59	PF00928	0.640
TRG_ER_diArg_1	184	187	PF00400	0.450
TRG_ER_diArg_1	189	192	PF00400	0.466
TRG_ER_FFAT_2	454	462	PF00635	0.576
TRG_Pf-PMV_PEXEL_1	65	69	PF00026	0.593

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P801	Leptomonas seymouri	46%	97%
A0A3Q8IKU6	Leishmania donovani	87%	100%
A4HK64	Leishmania braziliensis	65%	100%
A4I7P9	Leishmania infantum	88%	100%
E9B2K7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	99%