LeishMANIAdb
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Rubis-subs-bind domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Rubis-subs-bind domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q5J2_LEIMA
TriTrypDb:
LmjF.32.0900 , LMJLV39_320014700 * , LMJSD75_320014700 *
Length:
133

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q5J2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q5J2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 6 10 PF00656 0.682
CLV_NRD_NRD_1 118 120 PF00675 0.497
CLV_NRD_NRD_1 87 89 PF00675 0.542
CLV_PCSK_KEX2_1 85 87 PF00082 0.519
CLV_PCSK_PC1ET2_1 85 87 PF00082 0.652
CLV_PCSK_PC7_1 82 88 PF00082 0.652
DOC_USP7_MATH_1 113 117 PF00917 0.480
DOC_USP7_UBL2_3 97 101 PF12436 0.637
DOC_WW_Pin1_4 114 119 PF00397 0.620
LIG_BIR_II_1 1 5 PF00653 0.794
LIG_FHA_1 10 16 PF00498 0.714
LIG_SH2_GRB2like 72 75 PF00017 0.628
LIG_SH2_STAT5 72 75 PF00017 0.470
LIG_TRAF2_1 44 47 PF00917 0.641
LIG_TRAF2_1 52 55 PF00917 0.437
LIG_TRAF2_1 63 66 PF00917 0.558
MOD_CAAXbox 130 133 PF01239 0.630
MOD_CDC14_SPxK_1 117 120 PF00782 0.488
MOD_CDK_SPK_2 114 119 PF00069 0.620
MOD_CDK_SPxK_1 114 120 PF00069 0.481
MOD_CK1_1 17 23 PF00069 0.586
MOD_CK1_1 2 8 PF00069 0.769
MOD_GSK3_1 1 8 PF00069 0.780
MOD_N-GLC_1 73 78 PF02516 0.626
MOD_NEK2_1 1 6 PF00069 0.719
MOD_NEK2_1 14 19 PF00069 0.673
MOD_NEK2_1 38 43 PF00069 0.683
MOD_NEK2_1 73 78 PF00069 0.626
MOD_PIKK_1 9 15 PF00454 0.738
MOD_PIKK_1 90 96 PF00454 0.639
MOD_Plk_1 73 79 PF00069 0.556
MOD_ProDKin_1 114 120 PF00069 0.621
TRG_DiLeu_BaEn_4 54 60 PF01217 0.629
TRG_DiLeu_BaEn_4 65 71 PF01217 0.555
TRG_ER_diArg_1 86 88 PF00400 0.537
TRG_NLS_MonoCore_2 84 89 PF00514 0.586
TRG_NLS_MonoExtC_3 84 90 PF00514 0.583
TRG_NLS_MonoExtN_4 82 89 PF00514 0.582

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3Q8ID08 Leishmania donovani 93% 100%
A4HK71 Leishmania braziliensis 83% 100%
A4I7Q6 Leishmania infantum 94% 100%
E9B2L4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 100%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS