V-type proton ATPase subunit a

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

vacuolar proton-ATPase-like protein, putative

Species:

Leishmania major

UniProt:

Q4Q5J0_LEIMA

TriTrypDb:

LmjF.32.0920 , LMJLV39_320014900 , LMJSD75_320014900

Length:

893

Annotations

LeishMANIAdb annotations

Homologous to animal V-type proton pumps, vacuolar or lysosomal. For some reason, this family expanded in kinetoplastids. Localization: Endosomal (by homology) / Lysosomal (by homology)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 21
NetGPI	no	yes: 0, no: 21

Cellular components
Term	Name	Level	Count
GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain	5	22
GO:0016020	membrane	2	22
GO:0016469	proton-transporting two-sector ATPase complex	3	3
GO:0016471	vacuolar proton-transporting V-type ATPase complex	5	3
GO:0032991	protein-containing complex	1	22
GO:0033176	proton-transporting V-type ATPase complex	4	3
GO:0033177	proton-transporting two-sector ATPase complex, proton-transporting domain	3	22
GO:0033179	proton-transporting V-type ATPase, V0 domain	4	22
GO:0098796	membrane protein complex	2	22
GO:0110165	cellular anatomical entity	1	22
GO:0000323	lytic vacuole	6	1
GO:0005764	lysosome	7	1
GO:0005773	vacuole	5	1
GO:0005794	Golgi apparatus	5	1
GO:0020022	acidocalcisome	5	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

Expansion

Sequence features

Q4Q5J0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q5J0

Function

Biological processes
Term	Name	Level	Count
GO:0006873	intracellular monoatomic ion homeostasis	4	3
GO:0006885	regulation of pH	8	3
GO:0007035	vacuolar acidification	10	3
GO:0009987	cellular process	1	3
GO:0019725	cellular homeostasis	2	3
GO:0030003	intracellular monoatomic cation homeostasis	5	3
GO:0030004	obsolete cellular monovalent inorganic cation homeostasis	6	3
GO:0030641	regulation of cellular pH	7	3
GO:0042592	homeostatic process	3	3
GO:0048878	chemical homeostasis	4	3
GO:0050801	monoatomic ion homeostasis	5	3
GO:0051452	intracellular pH reduction	9	3
GO:0051453	regulation of intracellular pH	8	3
GO:0055067	obsolete monovalent inorganic cation homeostasis	7	3
GO:0055080	monoatomic cation homeostasis	6	3
GO:0055082	intracellular chemical homeostasis	3	3
GO:0065007	biological regulation	1	3
GO:0065008	regulation of biological quality	2	3
GO:0098771	inorganic ion homeostasis	6	3

Molecular functions
Term	Name	Level	Count
GO:0005215	transporter activity	1	22
GO:0005488	binding	1	3
GO:0005515	protein binding	2	3
GO:0008324	monoatomic cation transmembrane transporter activity	4	22
GO:0009678	pyrophosphate hydrolysis-driven proton transmembrane transporter activity	5	22
GO:0015075	monoatomic ion transmembrane transporter activity	3	22
GO:0015078	proton transmembrane transporter activity	5	22
GO:0015318	inorganic molecular entity transmembrane transporter activity	3	22
GO:0015399	primary active transmembrane transporter activity	4	22
GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	3	22
GO:0019899	enzyme binding	3	3
GO:0022804	active transmembrane transporter activity	3	22
GO:0022853	active monoatomic ion transmembrane transporter activity	4	22
GO:0022857	transmembrane transporter activity	2	22
GO:0022890	inorganic cation transmembrane transporter activity	4	22
GO:0042625	ATPase-coupled ion transmembrane transporter activity	3	22
GO:0042626	ATPase-coupled transmembrane transporter activity	2	22
GO:0044769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	4	22
GO:0046961	proton-transporting ATPase activity, rotational mechanism	4	22
GO:0051117	ATPase binding	4	3
GO:0140657	ATP-dependent activity	1	22
GO:0003824	catalytic activity	1	2
GO:0016787	hydrolase activity	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	696	700	PF00656	0.368
CLV_NRD_NRD_1	292	294	PF00675	0.479
CLV_NRD_NRD_1	347	349	PF00675	0.491
CLV_NRD_NRD_1	63	65	PF00675	0.448
CLV_NRD_NRD_1	671	673	PF00675	0.241
CLV_NRD_NRD_1	679	681	PF00675	0.251
CLV_NRD_NRD_1	69	71	PF00675	0.444
CLV_PCSK_FUR_1	292	296	PF00082	0.410
CLV_PCSK_KEX2_1	292	294	PF00082	0.522
CLV_PCSK_KEX2_1	347	349	PF00082	0.512
CLV_PCSK_KEX2_1	63	65	PF00082	0.448
CLV_PCSK_KEX2_1	666	668	PF00082	0.267
CLV_PCSK_KEX2_1	670	672	PF00082	0.250
CLV_PCSK_KEX2_1	678	680	PF00082	0.232
CLV_PCSK_PC1ET2_1	294	296	PF00082	0.523
CLV_PCSK_PC1ET2_1	666	668	PF00082	0.273
CLV_PCSK_PC7_1	667	673	PF00082	0.309
CLV_PCSK_SKI1_1	26	30	PF00082	0.525
CLV_PCSK_SKI1_1	295	299	PF00082	0.458
CLV_PCSK_SKI1_1	316	320	PF00082	0.466
CLV_PCSK_SKI1_1	347	351	PF00082	0.440
CLV_PCSK_SKI1_1	459	463	PF00082	0.297
CLV_PCSK_SKI1_1	56	60	PF00082	0.542
CLV_PCSK_SKI1_1	573	577	PF00082	0.267
DEG_APCC_DBOX_1	458	466	PF00400	0.304
DEG_SCF_TRCP1_1	716	721	PF00400	0.354
DOC_CKS1_1	156	161	PF01111	0.238
DOC_CKS1_1	505	510	PF01111	0.334
DOC_CYCLIN_RxL_1	64	78	PF00134	0.321
DOC_CYCLIN_yClb1_LxF_4	532	537	PF00134	0.266
DOC_MAPK_gen_1	205	215	PF00069	0.279
DOC_MAPK_gen_1	249	257	PF00069	0.296
DOC_MAPK_gen_1	292	300	PF00069	0.286
DOC_MAPK_gen_1	306	314	PF00069	0.266
DOC_MAPK_gen_1	515	524	PF00069	0.154
DOC_MAPK_gen_1	542	551	PF00069	0.246
DOC_MAPK_gen_1	683	692	PF00069	0.518
DOC_MAPK_MEF2A_6	13	22	PF00069	0.331
DOC_MAPK_MEF2A_6	249	257	PF00069	0.293
DOC_MAPK_MEF2A_6	542	551	PF00069	0.252
DOC_PP1_RVXF_1	532	538	PF00149	0.279
DOC_PP1_RVXF_1	571	577	PF00149	0.517
DOC_PP1_RVXF_1	68	75	PF00149	0.317
DOC_PP1_RVXF_1	861	867	PF00149	0.446
DOC_PP2B_LxvP_1	577	580	PF13499	0.348
DOC_PP2B_LxvP_1	655	658	PF13499	0.319
DOC_PP4_FxxP_1	54	57	PF00568	0.266
DOC_PP4_FxxP_1	621	624	PF00568	0.246
DOC_PP4_FxxP_1	745	748	PF00568	0.354
DOC_USP7_MATH_1	164	168	PF00917	0.319
DOC_USP7_MATH_1	174	178	PF00917	0.306
DOC_USP7_MATH_1	233	237	PF00917	0.316
DOC_USP7_MATH_1	353	357	PF00917	0.311
DOC_USP7_MATH_1	705	709	PF00917	0.470
DOC_USP7_MATH_1	748	752	PF00917	0.381
DOC_USP7_UBL2_3	309	313	PF12436	0.332
DOC_USP7_UBL2_3	569	573	PF12436	0.532
DOC_WW_Pin1_4	155	160	PF00397	0.332
DOC_WW_Pin1_4	240	245	PF00397	0.261
DOC_WW_Pin1_4	504	509	PF00397	0.247
LIG_14-3-3_CanoR_1	103	107	PF00244	0.295
LIG_14-3-3_CanoR_1	183	188	PF00244	0.309
LIG_14-3-3_CanoR_1	306	312	PF00244	0.294
LIG_14-3-3_CanoR_1	382	390	PF00244	0.332
LIG_14-3-3_CanoR_1	683	692	PF00244	0.438
LIG_APCC_ABBA_1	365	370	PF00400	0.238
LIG_BRCT_BRCA1_1	177	181	PF00533	0.290
LIG_BRCT_BRCA1_1	811	815	PF00533	0.306
LIG_BRCT_BRCA1_1	828	832	PF00533	0.252
LIG_Clathr_ClatBox_1	849	853	PF01394	0.297
LIG_CSL_BTD_1	336	339	PF09270	0.252
LIG_CtBP_PxDLS_1	883	887	PF00389	0.516
LIG_deltaCOP1_diTrp_1	568	578	PF00928	0.487
LIG_EH1_1	770	778	PF00400	0.532
LIG_eIF4E_1	149	155	PF01652	0.238
LIG_eIF4E_1	572	578	PF01652	0.438
LIG_EVH1_2	374	378	PF00568	0.266
LIG_FHA_1	124	130	PF00498	0.287
LIG_FHA_1	443	449	PF00498	0.438
LIG_FHA_1	57	63	PF00498	0.262
LIG_FHA_1	685	691	PF00498	0.479
LIG_FHA_1	731	737	PF00498	0.557
LIG_FHA_1	755	761	PF00498	0.438
LIG_FHA_1	821	827	PF00498	0.258
LIG_FHA_1	843	849	PF00498	0.289
LIG_FHA_2	119	125	PF00498	0.329
LIG_FHA_2	128	134	PF00498	0.272
LIG_FHA_2	156	162	PF00498	0.210
LIG_FHA_2	261	267	PF00498	0.285
LIG_FHA_2	30	36	PF00498	0.283
LIG_FHA_2	374	380	PF00498	0.249
LIG_FHA_2	757	763	PF00498	0.519
LIG_FHA_2	96	102	PF00498	0.295
LIG_LIR_Apic_2	52	57	PF02991	0.268
LIG_LIR_Apic_2	618	624	PF02991	0.250
LIG_LIR_Gen_1	178	188	PF02991	0.334
LIG_LIR_Gen_1	235	244	PF02991	0.283
LIG_LIR_Gen_1	310	319	PF02991	0.258
LIG_LIR_Gen_1	536	546	PF02991	0.246
LIG_LIR_Gen_1	581	589	PF02991	0.302
LIG_LIR_Gen_1	766	776	PF02991	0.476
LIG_LIR_Gen_1	795	806	PF02991	0.446
LIG_LIR_Nem_3	178	184	PF02991	0.311
LIG_LIR_Nem_3	186	191	PF02991	0.278
LIG_LIR_Nem_3	235	240	PF02991	0.281
LIG_LIR_Nem_3	310	314	PF02991	0.262
LIG_LIR_Nem_3	335	340	PF02991	0.323
LIG_LIR_Nem_3	384	390	PF02991	0.248
LIG_LIR_Nem_3	411	415	PF02991	0.255
LIG_LIR_Nem_3	466	471	PF02991	0.364
LIG_LIR_Nem_3	478	482	PF02991	0.187
LIG_LIR_Nem_3	492	496	PF02991	0.214
LIG_LIR_Nem_3	536	541	PF02991	0.246
LIG_LIR_Nem_3	568	574	PF02991	0.485
LIG_LIR_Nem_3	581	585	PF02991	0.294
LIG_LIR_Nem_3	588	594	PF02991	0.286
LIG_LIR_Nem_3	766	771	PF02991	0.459
LIG_LIR_Nem_3	795	801	PF02991	0.446
LIG_LIR_Nem_3	812	818	PF02991	0.297
LIG_PCNA_PIPBox_1	852	861	PF02747	0.446
LIG_Pex14_2	383	387	PF04695	0.255
LIG_Pex14_2	412	416	PF04695	0.246
LIG_Pex14_2	427	431	PF04695	0.297
LIG_Pex14_2	54	58	PF04695	0.283
LIG_Pex14_2	555	559	PF04695	0.365
LIG_Pex14_2	578	582	PF04695	0.378
LIG_Pex14_2	869	873	PF04695	0.446
LIG_PTB_Apo_2	474	481	PF02174	0.297
LIG_PTB_Apo_2	561	568	PF02174	0.306
LIG_PTB_Apo_2	626	633	PF02174	0.238
LIG_PTB_Apo_2	691	698	PF02174	0.382
LIG_PTB_Apo_2	868	875	PF02174	0.451
LIG_PTB_Phospho_1	561	567	PF10480	0.306
LIG_PTB_Phospho_1	691	697	PF10480	0.354
LIG_PTB_Phospho_1	868	874	PF10480	0.451
LIG_REV1ctd_RIR_1	433	443	PF16727	0.285
LIG_SH2_CRK	152	156	PF00017	0.238
LIG_SH2_CRK	471	475	PF00017	0.441
LIG_SH2_CRK	538	542	PF00017	0.246
LIG_SH2_CRK	591	595	PF00017	0.297
LIG_SH2_NCK_1	697	701	PF00017	0.410
LIG_SH2_SRC	169	172	PF00017	0.349
LIG_SH2_SRC	302	305	PF00017	0.324
LIG_SH2_SRC	780	783	PF00017	0.466
LIG_SH2_STAP1	567	571	PF00017	0.532
LIG_SH2_STAP1	697	701	PF00017	0.410
LIG_SH2_STAT5	262	265	PF00017	0.341
LIG_SH2_STAT5	311	314	PF00017	0.294
LIG_SH2_STAT5	414	417	PF00017	0.297
LIG_SH2_STAT5	460	463	PF00017	0.291
LIG_SH2_STAT5	491	494	PF00017	0.283
LIG_SH2_STAT5	659	662	PF00017	0.545
LIG_SH2_STAT5	697	700	PF00017	0.410
LIG_SH2_STAT5	780	783	PF00017	0.447
LIG_SH2_STAT5	787	790	PF00017	0.445
LIG_SH2_STAT5	798	801	PF00017	0.433
LIG_SH3_3	153	159	PF00018	0.365
LIG_SH3_3	502	508	PF00018	0.278
LIG_SH3_3	511	517	PF00018	0.278
LIG_SH3_3	624	630	PF00018	0.236
LIG_SUMO_SIM_anti_2	593	598	PF11976	0.348
LIG_SUMO_SIM_anti_2	612	618	PF11976	0.120
LIG_SUMO_SIM_par_1	211	216	PF11976	0.267
LIG_SUMO_SIM_par_1	460	466	PF11976	0.285
LIG_SUMO_SIM_par_1	612	618	PF11976	0.332
LIG_SUMO_SIM_par_1	687	693	PF11976	0.528
LIG_SUMO_SIM_par_1	822	827	PF11976	0.326
LIG_SUMO_SIM_par_1	882	887	PF11976	0.396
LIG_TRAF2_1	751	754	PF00917	0.507
LIG_TRAF2_1	98	101	PF00917	0.332
LIG_TRFH_1	620	624	PF08558	0.297
LIG_TYR_ITIM	418	423	PF00017	0.315
LIG_UBA3_1	187	194	PF00899	0.404
LIG_UBA3_1	246	252	PF00899	0.417
LIG_UBA3_1	430	439	PF00899	0.313
LIG_UBA3_1	594	599	PF00899	0.265
LIG_WRC_WIRS_1	586	591	PF05994	0.279
LIG_WRC_WIRS_1	815	820	PF05994	0.353
LIG_WW_3	515	519	PF00397	0.168
MOD_CK1_1	165	171	PF00069	0.320
MOD_CK1_1	193	199	PF00069	0.369
MOD_CK1_1	328	334	PF00069	0.311
MOD_CK1_1	360	366	PF00069	0.357
MOD_CK1_1	489	495	PF00069	0.331
MOD_CK1_1	688	694	PF00069	0.356
MOD_CK1_1	695	701	PF00069	0.358
MOD_CK1_1	756	762	PF00069	0.426
MOD_CK1_1	790	796	PF00069	0.455
MOD_CK1_1	809	815	PF00069	0.294
MOD_CK2_1	118	124	PF00069	0.311
MOD_CK2_1	127	133	PF00069	0.253
MOD_CK2_1	260	266	PF00069	0.359
MOD_CK2_1	29	35	PF00069	0.397
MOD_CK2_1	373	379	PF00069	0.342
MOD_CK2_1	562	568	PF00069	0.285
MOD_CK2_1	609	615	PF00069	0.314
MOD_CK2_1	714	720	PF00069	0.265
MOD_CK2_1	748	754	PF00069	0.448
MOD_CK2_1	756	762	PF00069	0.421
MOD_CK2_1	95	101	PF00069	0.363
MOD_GlcNHglycan	327	330	PF01048	0.309
MOD_GlcNHglycan	334	337	PF01048	0.301
MOD_GlcNHglycan	355	358	PF01048	0.327
MOD_GlcNHglycan	488	491	PF01048	0.305
MOD_GlcNHglycan	704	708	PF01048	0.389
MOD_GlcNHglycan	716	719	PF01048	0.400
MOD_GlcNHglycan	720	723	PF01048	0.423
MOD_GlcNHglycan	8	11	PF01048	0.465
MOD_GlcNHglycan	829	832	PF01048	0.319
MOD_GlcNHglycan	855	858	PF01048	0.302
MOD_GlcNHglycan	95	98	PF01048	0.368
MOD_GSK3_1	123	130	PF00069	0.429
MOD_GSK3_1	175	182	PF00069	0.394
MOD_GSK3_1	272	279	PF00069	0.323
MOD_GSK3_1	317	324	PF00069	0.318
MOD_GSK3_1	328	335	PF00069	0.294
MOD_GSK3_1	353	360	PF00069	0.334
MOD_GSK3_1	373	380	PF00069	0.266
MOD_GSK3_1	485	492	PF00069	0.382
MOD_GSK3_1	499	506	PF00069	0.359
MOD_GSK3_1	558	565	PF00069	0.285
MOD_GSK3_1	600	607	PF00069	0.330
MOD_GSK3_1	684	691	PF00069	0.386
MOD_GSK3_1	714	721	PF00069	0.427
MOD_GSK3_1	749	756	PF00069	0.422
MOD_GSK3_1	788	795	PF00069	0.301
MOD_GSK3_1	802	809	PF00069	0.287
MOD_GSK3_1	816	823	PF00069	0.351
MOD_GSK3_1	884	891	PF00069	0.550
MOD_N-GLC_1	165	170	PF02516	0.283
MOD_N-GLC_1	357	362	PF02516	0.417
MOD_N-GLC_1	562	567	PF02516	0.276
MOD_N-GLC_1	827	832	PF02516	0.422
MOD_N-GLC_2	323	325	PF02516	0.324
MOD_NEK2_1	102	107	PF00069	0.369
MOD_NEK2_1	162	167	PF00069	0.373
MOD_NEK2_1	190	195	PF00069	0.438
MOD_NEK2_1	274	279	PF00069	0.342
MOD_NEK2_1	29	34	PF00069	0.345
MOD_NEK2_1	307	312	PF00069	0.375
MOD_NEK2_1	327	332	PF00069	0.275
MOD_NEK2_1	377	382	PF00069	0.342
MOD_NEK2_1	383	388	PF00069	0.329
MOD_NEK2_1	463	468	PF00069	0.346
MOD_NEK2_1	480	485	PF00069	0.182
MOD_NEK2_1	486	491	PF00069	0.345
MOD_NEK2_1	537	542	PF00069	0.313
MOD_NEK2_1	558	563	PF00069	0.361
MOD_NEK2_1	585	590	PF00069	0.298
MOD_NEK2_1	685	690	PF00069	0.354
MOD_NEK2_1	806	811	PF00069	0.326
MOD_NEK2_1	816	821	PF00069	0.307
MOD_NEK2_1	884	889	PF00069	0.524
MOD_OFUCOSY	325	332	PF10250	0.325
MOD_PIKK_1	806	812	PF00454	0.307
MOD_PK_1	609	615	PF00069	0.285
MOD_PKA_2	102	108	PF00069	0.281
MOD_PKA_2	204	210	PF00069	0.303
MOD_PKA_2	381	387	PF00069	0.372
MOD_PKA_2	685	691	PF00069	0.296
MOD_PKA_2	711	717	PF00069	0.342
MOD_Plk_1	118	124	PF00069	0.341
MOD_Plk_1	165	171	PF00069	0.354
MOD_Plk_1	283	289	PF00069	0.435
MOD_Plk_1	342	348	PF00069	0.404
MOD_Plk_1	562	568	PF00069	0.276
MOD_Plk_1	75	81	PF00069	0.372
MOD_Plk_2-3	260	266	PF00069	0.226
MOD_Plk_4	102	108	PF00069	0.316
MOD_Plk_4	183	189	PF00069	0.417
MOD_Plk_4	233	239	PF00069	0.376
MOD_Plk_4	242	248	PF00069	0.317
MOD_Plk_4	29	35	PF00069	0.334
MOD_Plk_4	296	302	PF00069	0.291
MOD_Plk_4	307	313	PF00069	0.341
MOD_Plk_4	360	366	PF00069	0.306
MOD_Plk_4	373	379	PF00069	0.266
MOD_Plk_4	463	469	PF00069	0.380
MOD_Plk_4	562	568	PF00069	0.340
MOD_Plk_4	590	596	PF00069	0.344
MOD_Plk_4	609	615	PF00069	0.256
MOD_Plk_4	685	691	PF00069	0.383
MOD_Plk_4	756	762	PF00069	0.427
MOD_Plk_4	794	800	PF00069	0.297
MOD_ProDKin_1	155	161	PF00069	0.417
MOD_ProDKin_1	240	246	PF00069	0.318
MOD_ProDKin_1	504	510	PF00069	0.298
MOD_SUMO_for_1	312	315	PF00179	0.417
MOD_SUMO_rev_2	186	196	PF00179	0.246
MOD_SUMO_rev_2	497	502	PF00179	0.246
MOD_SUMO_rev_2	530	535	PF00179	0.298
TRG_DiLeu_BaEn_1	581	586	PF01217	0.348
TRG_DiLeu_BaEn_2	217	223	PF01217	0.285
TRG_DiLeu_BaEn_4	197	203	PF01217	0.417
TRG_DiLeu_BaLyEn_6	150	155	PF01217	0.246
TRG_ENDOCYTIC_2	152	155	PF00928	0.417
TRG_ENDOCYTIC_2	311	314	PF00928	0.317
TRG_ENDOCYTIC_2	399	402	PF00928	0.239
TRG_ENDOCYTIC_2	420	423	PF00928	0.295
TRG_ENDOCYTIC_2	460	463	PF00928	0.297
TRG_ENDOCYTIC_2	471	474	PF00928	0.297
TRG_ENDOCYTIC_2	476	479	PF00928	0.297
TRG_ENDOCYTIC_2	538	541	PF00928	0.297
TRG_ENDOCYTIC_2	591	594	PF00928	0.297
TRG_ENDOCYTIC_2	659	662	PF00928	0.431
TRG_ENDOCYTIC_2	798	801	PF00928	0.297
TRG_ER_diArg_1	292	295	PF00400	0.353
TRG_ER_diArg_1	346	348	PF00400	0.422
TRG_ER_diArg_1	62	64	PF00400	0.306
TRG_ER_diArg_1	670	672	PF00400	0.278
TRG_ER_diArg_1	678	680	PF00400	0.310
TRG_NES_CRM1_1	853	868	PF08389	0.297
TRG_Pf-PMV_PEXEL_1	153	157	PF00026	0.447
TRG_Pf-PMV_PEXEL_1	348	352	PF00026	0.359
TRG_Pf-PMV_PEXEL_1	724	729	PF00026	0.285

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P622	Leptomonas seymouri	41%	100%
A0A0N1PFQ1	Leptomonas seymouri	70%	97%
A0A0S4JG87	Bodo saltans	37%	99%
A0A0S4JMR5	Bodo saltans	43%	100%
A0A1X0NV83	Trypanosomatidae	50%	100%
A0A1X0NWN0	Trypanosomatidae	43%	100%
A0A3Q8IB62	Leishmania donovani	43%	100%
A0A3Q8IGN1	Leishmania donovani	95%	100%
A0A3R7KUW1	Trypanosoma rangeli	48%	100%
A0A422NJD7	Trypanosoma rangeli	42%	100%
A1A5G6	Xenopus tropicalis	33%	100%
A4HD35	Leishmania braziliensis	41%	100%
A4HK73	Leishmania braziliensis	85%	100%
A4I0M2	Leishmania infantum	42%	100%
A4I7Q8	Leishmania infantum	95%	100%
B2MZD0	Caenorhabditis elegans	30%	74%
C9ZNR3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
E9AWI3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9B2L6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
G5EEK9	Caenorhabditis elegans	31%	100%
G5EGP4	Caenorhabditis elegans	27%	100%
O13742	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	30%	100%
O97681	Bos taurus	31%	100%
P15920	Mus musculus	31%	100%
P25286	Rattus norvegicus	32%	100%
P30628	Caenorhabditis elegans	30%	99%
P32563	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	30%	100%
P37296	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	30%	100%
Q01290	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	32%	100%
Q13488	Homo sapiens	31%	100%
Q29466	Bos taurus	33%	100%
Q4QAY7	Leishmania major	42%	100%
Q54E04	Dictyostelium discoideum	34%	100%
Q5R422	Pongo abelii	32%	100%
Q8AVM5	Xenopus laevis	33%	100%
Q8RWZ7	Arabidopsis thaliana	31%	100%
Q8W4S4	Arabidopsis thaliana	34%	100%
Q920R6	Mus musculus	32%	100%
Q93050	Homo sapiens	33%	100%
Q9HBG4	Homo sapiens	33%	100%
Q9I8D0	Gallus gallus	30%	100%
Q9SJT7	Arabidopsis thaliana	32%	100%
Q9Y487	Homo sapiens	31%	100%
Q9Z1G4	Mus musculus	32%	100%
V5BQN9	Trypanosoma cruzi	51%	100%
V5D763	Trypanosoma cruzi	42%	100%