Staphylococcal nuclease domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Staphylococcal nuclease homologue/Tudor domain containing protein, putative

Species:

Leishmania major

UniProt:

Q4Q5I7_LEIMA

TriTrypDb:

LmjF.32.0950 , LMJLV39_320015300 , LMJSD75_320015300

Length:

934

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	yes	yes: 4
Pissara et al.	yes	yes: 16

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 7

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	2
GO:0005737	cytoplasm	2	11
GO:0005829	cytosol	2	2
GO:0016442	RISC complex	4	11
GO:0031332	RNAi effector complex	3	11
GO:0031974	membrane-enclosed lumen	2	2
GO:0031981	nuclear lumen	5	2
GO:0032838	plasma membrane bounded cell projection cytoplasm	4	2
GO:0032991	protein-containing complex	1	11
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0043233	organelle lumen	3	2
GO:0070013	intracellular organelle lumen	4	2
GO:0097014	ciliary plasm	5	2
GO:0099568	cytoplasmic region	3	2
GO:0110165	cellular anatomical entity	1	11
GO:1990904	ribonucleoprotein complex	2	11

Expansion

Sequence features

Q4Q5I7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q5I7

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	2
GO:0006401	RNA catabolic process	5	2
GO:0006402	mRNA catabolic process	6	2
GO:0006725	cellular aromatic compound metabolic process	3	2
GO:0006807	nitrogen compound metabolic process	2	2
GO:0008152	metabolic process	1	2
GO:0009056	catabolic process	2	2
GO:0009057	macromolecule catabolic process	4	2
GO:0009892	negative regulation of metabolic process	4	11
GO:0009987	cellular process	1	2
GO:0010468	regulation of gene expression	5	11
GO:0010605	negative regulation of macromolecule metabolic process	5	11
GO:0010629	negative regulation of gene expression	6	11
GO:0016070	RNA metabolic process	5	2
GO:0016071	mRNA metabolic process	6	2
GO:0019222	regulation of metabolic process	3	11
GO:0019439	aromatic compound catabolic process	4	2
GO:0031047	RNA-mediated gene silencing	7	11
GO:0034641	cellular nitrogen compound metabolic process	3	2
GO:0034655	nucleobase-containing compound catabolic process	4	2
GO:0043170	macromolecule metabolic process	3	2
GO:0044237	cellular metabolic process	2	2
GO:0044238	primary metabolic process	2	2
GO:0044248	cellular catabolic process	3	2
GO:0044260	obsolete cellular macromolecule metabolic process	3	2
GO:0044265	obsolete cellular macromolecule catabolic process	4	2
GO:0044270	cellular nitrogen compound catabolic process	4	2
GO:0046483	heterocycle metabolic process	3	2
GO:0046700	heterocycle catabolic process	4	2
GO:0048519	negative regulation of biological process	3	11
GO:0050789	regulation of biological process	2	11
GO:0060255	regulation of macromolecule metabolic process	4	11
GO:0065007	biological regulation	1	11
GO:0071704	organic substance metabolic process	2	2
GO:0090304	nucleic acid metabolic process	4	2
GO:1901360	organic cyclic compound metabolic process	3	2
GO:1901361	organic cyclic compound catabolic process	4	2
GO:1901575	organic substance catabolic process	3	2

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	2
GO:0003723	RNA binding	4	2
GO:0003824	catalytic activity	1	11
GO:0004518	nuclease activity	4	11
GO:0005488	binding	1	2
GO:0016787	hydrolase activity	2	11
GO:0016788	hydrolase activity, acting on ester bonds	3	11
GO:0097159	organic cyclic compound binding	2	2
GO:1901363	heterocyclic compound binding	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	205	209	PF00656	0.657
CLV_C14_Caspase3-7	236	240	PF00656	0.404
CLV_C14_Caspase3-7	345	349	PF00656	0.703
CLV_C14_Caspase3-7	848	852	PF00656	0.488
CLV_NRD_NRD_1	136	138	PF00675	0.476
CLV_NRD_NRD_1	42	44	PF00675	0.404
CLV_NRD_NRD_1	733	735	PF00675	0.334
CLV_NRD_NRD_1	894	896	PF00675	0.588
CLV_NRD_NRD_1	905	907	PF00675	0.492
CLV_NRD_NRD_1	914	916	PF00675	0.287
CLV_PCSK_KEX2_1	291	293	PF00082	0.437
CLV_PCSK_KEX2_1	42	44	PF00082	0.369
CLV_PCSK_KEX2_1	894	896	PF00082	0.555
CLV_PCSK_KEX2_1	905	907	PF00082	0.471
CLV_PCSK_PC1ET2_1	291	293	PF00082	0.437
CLV_PCSK_SKI1_1	13	17	PF00082	0.546
CLV_PCSK_SKI1_1	138	142	PF00082	0.448
CLV_PCSK_SKI1_1	229	233	PF00082	0.382
CLV_PCSK_SKI1_1	28	32	PF00082	0.373
CLV_PCSK_SKI1_1	421	425	PF00082	0.364
CLV_PCSK_SKI1_1	607	611	PF00082	0.490
CLV_PCSK_SKI1_1	666	670	PF00082	0.461
CLV_PCSK_SKI1_1	682	686	PF00082	0.421
DEG_APCC_DBOX_1	385	393	PF00400	0.385
DEG_APCC_DBOX_1	526	534	PF00400	0.566
DEG_APCC_DBOX_1	860	868	PF00400	0.521
DEG_APCC_KENBOX_2	563	567	PF00400	0.515
DEG_COP1_1	870	880	PF00400	0.587
DOC_CDC14_PxL_1	34	42	PF14671	0.404
DOC_CKS1_1	576	581	PF01111	0.385
DOC_CYCLIN_RxL_1	134	144	PF00134	0.478
DOC_CYCLIN_RxL_1	884	893	PF00134	0.543
DOC_MAPK_DCC_7	297	305	PF00069	0.642
DOC_MAPK_gen_1	447	457	PF00069	0.446
DOC_MAPK_gen_1	525	532	PF00069	0.462
DOC_MAPK_gen_1	780	788	PF00069	0.533
DOC_MAPK_MEF2A_6	178	186	PF00069	0.500
DOC_MAPK_MEF2A_6	266	274	PF00069	0.439
DOC_MAPK_MEF2A_6	458	466	PF00069	0.473
DOC_MAPK_MEF2A_6	546	553	PF00069	0.478
DOC_MAPK_MEF2A_6	564	573	PF00069	0.357
DOC_PP1_RVXF_1	68	75	PF00149	0.369
DOC_PP1_RVXF_1	785	792	PF00149	0.566
DOC_PP2B_LxvP_1	776	779	PF13499	0.603
DOC_PP4_FxxP_1	567	570	PF00568	0.408
DOC_USP7_MATH_1	251	255	PF00917	0.446
DOC_USP7_MATH_1	328	332	PF00917	0.839
DOC_USP7_UBL2_3	262	266	PF12436	0.516
DOC_USP7_UBL2_3	498	502	PF12436	0.494
DOC_USP7_UBL2_3	783	787	PF12436	0.582
DOC_WW_Pin1_4	178	183	PF00397	0.482
DOC_WW_Pin1_4	247	252	PF00397	0.446
DOC_WW_Pin1_4	347	352	PF00397	0.717
DOC_WW_Pin1_4	403	408	PF00397	0.369
DOC_WW_Pin1_4	47	52	PF00397	0.490
DOC_WW_Pin1_4	505	510	PF00397	0.660
DOC_WW_Pin1_4	575	580	PF00397	0.385
DOC_WW_Pin1_4	750	755	PF00397	0.578
DOC_WW_Pin1_4	814	819	PF00397	0.576
LIG_14-3-3_CanoR_1	150	156	PF00244	0.576
LIG_14-3-3_CanoR_1	386	390	PF00244	0.384
LIG_14-3-3_CanoR_1	410	414	PF00244	0.369
LIG_14-3-3_CanoR_1	42	49	PF00244	0.405
LIG_14-3-3_CanoR_1	450	456	PF00244	0.482
LIG_14-3-3_CanoR_1	527	533	PF00244	0.586
LIG_14-3-3_CanoR_1	64	68	PF00244	0.385
LIG_14-3-3_CanoR_1	772	776	PF00244	0.613
LIG_14-3-3_CanoR_1	894	901	PF00244	0.570
LIG_Actin_WH2_2	530	548	PF00022	0.484
LIG_Actin_WH2_2	816	832	PF00022	0.601
LIG_AP2alpha_2	590	592	PF02296	0.426
LIG_APCC_ABBAyCdc20_2	501	507	PF00400	0.439
LIG_BIR_II_1	1	5	PF00653	0.447
LIG_BIR_III_4	379	383	PF00653	0.604
LIG_BIR_III_4	660	664	PF00653	0.400
LIG_BRCT_BRCA1_1	45	49	PF00533	0.439
LIG_BRCT_BRCA1_1	579	583	PF00533	0.455
LIG_CAP-Gly_1	928	934	PF01302	0.730
LIG_CtBP_PxDLS_1	157	161	PF00389	0.631
LIG_deltaCOP1_diTrp_1	415	423	PF00928	0.385
LIG_EH1_1	219	227	PF00400	0.516
LIG_eIF4E_1	57	63	PF01652	0.490
LIG_FHA_1	181	187	PF00498	0.466
LIG_FHA_1	269	275	PF00498	0.445
LIG_FHA_1	354	360	PF00498	0.571
LIG_FHA_1	371	377	PF00498	0.303
LIG_FHA_1	444	450	PF00498	0.375
LIG_FHA_1	452	458	PF00498	0.385
LIG_FHA_1	473	479	PF00498	0.372
LIG_FHA_1	608	614	PF00498	0.464
LIG_FHA_1	674	680	PF00498	0.595
LIG_FHA_1	792	798	PF00498	0.591
LIG_FHA_1	97	103	PF00498	0.516
LIG_FHA_2	107	113	PF00498	0.402
LIG_FHA_2	18	24	PF00498	0.633
LIG_FHA_2	203	209	PF00498	0.521
LIG_FHA_2	274	280	PF00498	0.504
LIG_FHA_2	343	349	PF00498	0.682
LIG_FHA_2	410	416	PF00498	0.371
LIG_FHA_2	48	54	PF00498	0.462
LIG_FHA_2	625	631	PF00498	0.473
LIG_FHA_2	870	876	PF00498	0.437
LIG_IRF3_LxIS_1	182	188	PF10401	0.519
LIG_KLC1_Yacidic_2	76	81	PF13176	0.490
LIG_LIR_Apic_2	565	570	PF02991	0.421
LIG_LIR_Gen_1	124	133	PF02991	0.428
LIG_LIR_Gen_1	239	249	PF02991	0.454
LIG_LIR_Gen_1	261	272	PF02991	0.426
LIG_LIR_Gen_1	438	444	PF02991	0.445
LIG_LIR_Gen_1	470	478	PF02991	0.358
LIG_LIR_Gen_1	526	537	PF02991	0.579
LIG_LIR_Gen_1	785	795	PF02991	0.578
LIG_LIR_Gen_1	810	819	PF02991	0.575
LIG_LIR_Gen_1	842	849	PF02991	0.570
LIG_LIR_Nem_3	121	126	PF02991	0.373
LIG_LIR_Nem_3	2	6	PF02991	0.418
LIG_LIR_Nem_3	239	244	PF02991	0.375
LIG_LIR_Nem_3	26	30	PF02991	0.567
LIG_LIR_Nem_3	261	267	PF02991	0.426
LIG_LIR_Nem_3	412	416	PF02991	0.369
LIG_LIR_Nem_3	438	442	PF02991	0.445
LIG_LIR_Nem_3	470	476	PF02991	0.358
LIG_LIR_Nem_3	526	532	PF02991	0.571
LIG_LIR_Nem_3	705	711	PF02991	0.464
LIG_LIR_Nem_3	785	791	PF02991	0.528
LIG_LIR_Nem_3	810	814	PF02991	0.575
LIG_LIR_Nem_3	817	823	PF02991	0.573
LIG_LIR_Nem_3	842	846	PF02991	0.519
LIG_PTB_Apo_2	863	870	PF02174	0.521
LIG_PTB_Phospho_1	863	869	PF10480	0.524
LIG_REV1ctd_RIR_1	218	228	PF16727	0.516
LIG_REV1ctd_RIR_1	474	484	PF16727	0.426
LIG_SH2_CRK	355	359	PF00017	0.503
LIG_SH2_CRK	439	443	PF00017	0.454
LIG_SH2_CRK	811	815	PF00017	0.601
LIG_SH2_NCK_1	57	61	PF00017	0.490
LIG_SH2_NCK_1	843	847	PF00017	0.527
LIG_SH2_PTP2	264	267	PF00017	0.485
LIG_SH2_PTP2	299	302	PF00017	0.673
LIG_SH2_SRC	299	302	PF00017	0.637
LIG_SH2_SRC	79	82	PF00017	0.490
LIG_SH2_STAP1	416	420	PF00017	0.369
LIG_SH2_STAP1	439	443	PF00017	0.426
LIG_SH2_STAP1	473	477	PF00017	0.426
LIG_SH2_STAP1	55	59	PF00017	0.490
LIG_SH2_STAT5	264	267	PF00017	0.485
LIG_SH2_STAT5	299	302	PF00017	0.673
LIG_SH2_STAT5	3	6	PF00017	0.420
LIG_SH2_STAT5	34	37	PF00017	0.454
LIG_SH2_STAT5	355	358	PF00017	0.610
LIG_SH2_STAT5	428	431	PF00017	0.411
LIG_SH2_STAT5	529	532	PF00017	0.462
LIG_SH2_STAT5	561	564	PF00017	0.458
LIG_SH2_STAT5	724	727	PF00017	0.536
LIG_SH2_STAT5	79	82	PF00017	0.389
LIG_SH2_STAT5	828	831	PF00017	0.517
LIG_SH2_STAT5	869	872	PF00017	0.454
LIG_SH3_1	506	512	PF00018	0.660
LIG_SH3_1	803	809	PF00018	0.538
LIG_SH3_2	509	514	PF14604	0.631
LIG_SH3_3	176	182	PF00018	0.451
LIG_SH3_3	301	307	PF00018	0.717
LIG_SH3_3	331	337	PF00018	0.774
LIG_SH3_3	48	54	PF00018	0.426
LIG_SH3_3	506	512	PF00018	0.615
LIG_SH3_3	549	555	PF00018	0.464
LIG_SH3_3	557	563	PF00018	0.375
LIG_SH3_3	803	809	PF00018	0.540
LIG_SUMO_SIM_anti_2	183	188	PF11976	0.469
LIG_SUMO_SIM_anti_2	431	438	PF11976	0.283
LIG_SUMO_SIM_anti_2	635	640	PF11976	0.490
LIG_SUMO_SIM_par_1	181	188	PF11976	0.437
LIG_SUMO_SIM_par_1	244	250	PF11976	0.490
LIG_SUMO_SIM_par_1	372	379	PF11976	0.489
LIG_SUMO_SIM_par_1	431	438	PF11976	0.462
LIG_TRAF2_1	156	159	PF00917	0.591
LIG_TRAF2_1	254	257	PF00917	0.516
LIG_TRAF2_1	497	500	PF00917	0.489
LIG_TRAF2_1	50	53	PF00917	0.490
LIG_TRAF2_1	845	848	PF00917	0.556
LIG_TRAF2_1	909	912	PF00917	0.587
LIG_TYR_ITIM	233	238	PF00017	0.490
LIG_TYR_ITIM	437	442	PF00017	0.437
LIG_UBA3_1	184	190	PF00899	0.570
LIG_UBA3_1	245	252	PF00899	0.516
LIG_WRC_WIRS_1	473	478	PF05994	0.385
LIG_WRC_WIRS_1	529	534	PF05994	0.457
LIG_WW_3	114	118	PF00397	0.454
MOD_CDK_SPK_2	247	252	PF00069	0.446
MOD_CDK_SPK_2	750	755	PF00069	0.578
MOD_CDK_SPxK_1	750	756	PF00069	0.578
MOD_CDK_SPxxK_3	403	410	PF00069	0.369
MOD_CK1_1	127	133	PF00069	0.454
MOD_CK1_1	247	253	PF00069	0.369
MOD_CK1_1	406	412	PF00069	0.385
MOD_CK1_1	485	491	PF00069	0.405
MOD_CK1_1	624	630	PF00069	0.461
MOD_CK1_1	706	712	PF00069	0.534
MOD_CK2_1	171	177	PF00069	0.554
MOD_CK2_1	185	191	PF00069	0.550
MOD_CK2_1	251	257	PF00069	0.516
MOD_CK2_1	47	53	PF00069	0.420
MOD_CK2_1	847	853	PF00069	0.606
MOD_CK2_1	869	875	PF00069	0.444
MOD_CK2_1	876	882	PF00069	0.484
MOD_GlcNHglycan	129	132	PF01048	0.428
MOD_GlcNHglycan	141	144	PF01048	0.514
MOD_GlcNHglycan	282	285	PF01048	0.528
MOD_GlcNHglycan	317	320	PF01048	0.789
MOD_GlcNHglycan	378	383	PF01048	0.581
MOD_GlcNHglycan	45	48	PF01048	0.519
MOD_GlcNHglycan	579	582	PF01048	0.486
MOD_GlcNHglycan	673	676	PF01048	0.607
MOD_GlcNHglycan	764	767	PF01048	0.390
MOD_GlcNHglycan	830	833	PF01048	0.674
MOD_GlcNHglycan	85	88	PF01048	0.423
MOD_GlcNHglycan	896	899	PF01048	0.597
MOD_GSK3_1	247	254	PF00069	0.392
MOD_GSK3_1	268	275	PF00069	0.398
MOD_GSK3_1	43	50	PF00069	0.527
MOD_GSK3_1	468	475	PF00069	0.412
MOD_GSK3_1	702	709	PF00069	0.503
MOD_GSK3_1	762	769	PF00069	0.600
MOD_N-GLC_1	268	273	PF02516	0.429
MOD_N-GLC_1	607	612	PF02516	0.478
MOD_N-GLC_1	632	637	PF02516	0.426
MOD_N-GLC_1	743	748	PF02516	0.403
MOD_NEK2_1	129	134	PF00069	0.507
MOD_NEK2_1	185	190	PF00069	0.459
MOD_NEK2_1	192	197	PF00069	0.429
MOD_NEK2_1	361	366	PF00069	0.461
MOD_NEK2_1	385	390	PF00069	0.519
MOD_NEK2_1	423	428	PF00069	0.410
MOD_NEK2_1	468	473	PF00069	0.362
MOD_NEK2_1	521	526	PF00069	0.550
MOD_NEK2_1	62	67	PF00069	0.390
MOD_NEK2_1	622	627	PF00069	0.397
MOD_NEK2_1	83	88	PF00069	0.429
MOD_NEK2_2	472	477	PF00069	0.426
MOD_PIKK_1	124	130	PF00454	0.478
MOD_PIKK_1	192	198	PF00454	0.519
MOD_PK_1	756	762	PF00069	0.539
MOD_PKA_1	894	900	PF00069	0.613
MOD_PKA_2	385	391	PF00069	0.375
MOD_PKA_2	392	398	PF00069	0.362
MOD_PKA_2	409	415	PF00069	0.322
MOD_PKA_2	41	47	PF00069	0.407
MOD_PKA_2	63	69	PF00069	0.385
MOD_PKA_2	771	777	PF00069	0.613
MOD_PKA_2	894	900	PF00069	0.605
MOD_Plk_1	210	216	PF00069	0.659
MOD_Plk_1	268	274	PF00069	0.456
MOD_Plk_1	607	613	PF00069	0.478
MOD_Plk_1	632	638	PF00069	0.426
MOD_Plk_1	743	749	PF00069	0.569
MOD_Plk_1	766	772	PF00069	0.525
MOD_Plk_2-3	847	853	PF00069	0.606
MOD_Plk_4	180	186	PF00069	0.449
MOD_Plk_4	30	36	PF00069	0.479
MOD_Plk_4	361	367	PF00069	0.511
MOD_Plk_4	370	376	PF00069	0.466
MOD_Plk_4	472	478	PF00069	0.417
MOD_Plk_4	528	534	PF00069	0.450
MOD_Plk_4	63	69	PF00069	0.369
MOD_Plk_4	719	725	PF00069	0.505
MOD_Plk_4	756	762	PF00069	0.559
MOD_Plk_4	771	777	PF00069	0.575
MOD_ProDKin_1	178	184	PF00069	0.481
MOD_ProDKin_1	247	253	PF00069	0.446
MOD_ProDKin_1	347	353	PF00069	0.715
MOD_ProDKin_1	403	409	PF00069	0.369
MOD_ProDKin_1	47	53	PF00069	0.490
MOD_ProDKin_1	505	511	PF00069	0.661
MOD_ProDKin_1	575	581	PF00069	0.385
MOD_ProDKin_1	750	756	PF00069	0.578
MOD_ProDKin_1	814	820	PF00069	0.576
MOD_SUMO_for_1	497	500	PF00179	0.490
MOD_SUMO_for_1	684	687	PF00179	0.620
MOD_SUMO_rev_2	211	221	PF00179	0.493
MOD_SUMO_rev_2	325	334	PF00179	0.830
MOD_SUMO_rev_2	415	423	PF00179	0.447
MOD_SUMO_rev_2	494	504	PF00179	0.475
MOD_SUMO_rev_2	590	599	PF00179	0.369
MOD_SUMO_rev_2	781	789	PF00179	0.566
TRG_DiLeu_BaEn_1	58	63	PF01217	0.385
TRG_DiLeu_BaEn_2	216	222	PF01217	0.516
TRG_DiLeu_BaEn_2	418	424	PF01217	0.385
TRG_DiLeu_BaEn_2	594	600	PF01217	0.400
TRG_DiLeu_BaLyEn_6	221	226	PF01217	0.490
TRG_ENDOCYTIC_2	126	129	PF00928	0.384
TRG_ENDOCYTIC_2	235	238	PF00928	0.464
TRG_ENDOCYTIC_2	264	267	PF00928	0.458
TRG_ENDOCYTIC_2	439	442	PF00928	0.454
TRG_ENDOCYTIC_2	473	476	PF00928	0.369
TRG_ENDOCYTIC_2	529	532	PF00928	0.462
TRG_ENDOCYTIC_2	811	814	PF00928	0.601
TRG_ENDOCYTIC_2	843	846	PF00928	0.522
TRG_ENDOCYTIC_2	868	871	PF00928	0.433
TRG_ENDOCYTIC_2	924	927	PF00928	0.553
TRG_ER_diArg_1	424	427	PF00400	0.490
TRG_ER_diArg_1	525	528	PF00400	0.568
TRG_ER_diArg_1	904	906	PF00400	0.556
TRG_NLS_MonoCore_2	288	293	PF00514	0.439
TRG_NLS_MonoExtN_4	289	294	PF00514	0.439
TRG_Pf-PMV_PEXEL_1	120	124	PF00026	0.516

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IMX5	Leptomonas seymouri	77%	99%
A0A0S4KLR8	Bodo saltans	41%	100%
A0A1X0NW15	Trypanosomatidae	53%	100%
A0A3Q8IFE0	Leishmania donovani	96%	100%
A0A3R7K553	Trypanosoma rangeli	51%	100%
A4HK76	Leishmania braziliensis	87%	100%
A4I7R1	Leishmania infantum	97%	100%
D0A9W6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	100%
E9B2L9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
Q5REU4	Pongo abelii	28%	100%
Q66X93	Rattus norvegicus	28%	100%
Q78PY7	Mus musculus	28%	100%
Q7KZF4	Homo sapiens	28%	100%
Q7ZT42	Danio rerio	28%	100%
Q863B3	Bos taurus	28%	100%
Q8VZG7	Arabidopsis thaliana	27%	94%
Q9FLT0	Arabidopsis thaliana	27%	95%
Q9W0S7	Drosophila melanogaster	27%	100%
Q9Y7U7	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	26%	100%
V5BL57	Trypanosoma cruzi	50%	100%