RRM domain-containing protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q5I4_LEIMA

TriTrypDb:

LmjF.32.0980 , LMJLV39_320015600 , LMJSD75_320015600

Length:

560

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q5I4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q5I4

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	6
GO:0005488	binding	1	6
GO:0097159	organic cyclic compound binding	2	6
GO:1901363	heterocyclic compound binding	2	6

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	539	541	PF00675	0.754
CLV_PCSK_KEX2_1	242	244	PF00082	0.432
CLV_PCSK_KEX2_1	539	541	PF00082	0.751
CLV_PCSK_PC1ET2_1	242	244	PF00082	0.432
CLV_PCSK_SKI1_1	161	165	PF00082	0.466
CLV_PCSK_SKI1_1	213	217	PF00082	0.504
CLV_PCSK_SKI1_1	242	246	PF00082	0.436
CLV_PCSK_SKI1_1	279	283	PF00082	0.495
CLV_PCSK_SKI1_1	75	79	PF00082	0.540
DEG_APCC_DBOX_1	270	278	PF00400	0.534

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IMP7	Leptomonas seymouri	53%	100%
A0A1X0NUL4	Trypanosomatidae	33%	87%
A0A3S7X5C4	Leishmania donovani	94%	100%
A4HK79	Leishmania braziliensis	74%	100%
A4I7R4	Leishmania infantum	94%	100%
E9B2M2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%

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