LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q5F0_LEIMA
TriTrypDb:
LmjF.32.1320 , LMJLV39_320019300 * , LMJSD75_320019300
Length:
543

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 1
GO:0110165 cellular anatomical entity 1 1
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Expansion

Sequence features

Q4Q5F0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q5F0

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 135 137 PF00675 0.647
CLV_NRD_NRD_1 203 205 PF00675 0.642
CLV_NRD_NRD_1 291 293 PF00675 0.522
CLV_NRD_NRD_1 338 340 PF00675 0.596
CLV_NRD_NRD_1 513 515 PF00675 0.445
CLV_NRD_NRD_1 94 96 PF00675 0.427
CLV_PCSK_FUR_1 336 340 PF00082 0.544
CLV_PCSK_KEX2_1 203 205 PF00082 0.667
CLV_PCSK_KEX2_1 222 224 PF00082 0.656
CLV_PCSK_KEX2_1 291 293 PF00082 0.522
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Homologs

ProteinTaxonomySequence identityCoverage
A0A3Q8IKZ7 Leishmania donovani 92% 100%
A4HKC0 Leishmania braziliensis 68% 98%
A4I7U9 Leishmania infantum 92% 100%
E9B2Q7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 87% 100%
V5BL88 Trypanosoma cruzi 26% 87%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS