rRNA-processing protein FYV7

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

rRNA processing, putative

Species:

Leishmania major

UniProt:

Q4Q5D3_LEIMA

TriTrypDb:

LmjF.32.1490 , LMJLV39_320020900 , LMJSD75_320020900

Length:

190

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q5D3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q5D3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	101	103	PF00675	0.326
CLV_NRD_NRD_1	131	133	PF00675	0.375
CLV_NRD_NRD_1	157	159	PF00675	0.327
CLV_NRD_NRD_1	33	35	PF00675	0.337
CLV_NRD_NRD_1	47	49	PF00675	0.311
CLV_NRD_NRD_1	67	69	PF00675	0.150
CLV_NRD_NRD_1	7	9	PF00675	0.537
CLV_NRD_NRD_1	95	97	PF00675	0.319
CLV_PCSK_KEX2_1	101	103	PF00082	0.328
CLV_PCSK_KEX2_1	131	133	PF00082	0.346
CLV_PCSK_KEX2_1	167	169	PF00082	0.374
CLV_PCSK_KEX2_1	59	61	PF00082	0.383
CLV_PCSK_KEX2_1	6	8	PF00082	0.549
CLV_PCSK_KEX2_1	95	97	PF00082	0.321
CLV_PCSK_PC1ET2_1	101	103	PF00082	0.314
CLV_PCSK_PC1ET2_1	167	169	PF00082	0.427
CLV_PCSK_PC1ET2_1	59	61	PF00082	0.329
CLV_PCSK_PC1ET2_1	95	97	PF00082	0.313
CLV_PCSK_SKI1_1	161	165	PF00082	0.392
CLV_PCSK_SKI1_1	17	21	PF00082	0.562
CLV_PCSK_SKI1_1	69	73	PF00082	0.407
DOC_PP1_RVXF_1	184	190	PF00149	0.242
DOC_USP7_MATH_1	157	161	PF00917	0.436
DOC_USP7_MATH_1	174	178	PF00917	0.354
DOC_USP7_UBL2_3	167	171	PF12436	0.432
DOC_USP7_UBL2_3	93	97	PF12436	0.328
LIG_14-3-3_CanoR_1	26	30	PF00244	0.483
LIG_BIR_II_1	1	5	PF00653	0.694
LIG_FHA_2	106	112	PF00498	0.309
LIG_FHA_2	26	32	PF00498	0.551
LIG_FHA_2	87	93	PF00498	0.323
LIG_LIR_Nem_3	45	50	PF02991	0.309
LIG_REV1ctd_RIR_1	18	27	PF16727	0.568
LIG_SH2_CRK	120	124	PF00017	0.394
LIG_SH2_CRK	47	51	PF00017	0.329
LIG_SH2_NCK_1	120	124	PF00017	0.444
LIG_SH2_STAP1	84	88	PF00017	0.329
LIG_TRAF2_1	143	146	PF00917	0.334
MOD_CK1_1	121	127	PF00069	0.480
MOD_CK2_1	121	127	PF00069	0.375
MOD_CK2_1	175	181	PF00069	0.433
MOD_CK2_1	25	31	PF00069	0.512
MOD_CK2_1	74	80	PF00069	0.344
MOD_CK2_1	86	92	PF00069	0.237
MOD_Cter_Amidation	32	35	PF01082	0.549
MOD_Cter_Amidation	4	7	PF01082	0.645
MOD_GlcNHglycan	120	123	PF01048	0.407
MOD_GSK3_1	175	182	PF00069	0.432
MOD_NEK2_1	104	109	PF00069	0.389
MOD_PKA_2	157	163	PF00069	0.430
MOD_PKA_2	25	31	PF00069	0.475
MOD_Plk_1	84	90	PF00069	0.297
MOD_Plk_4	179	185	PF00069	0.371
MOD_Plk_4	25	31	PF00069	0.490
MOD_SUMO_for_1	13	16	PF00179	0.504
TRG_ENDOCYTIC_2	120	123	PF00928	0.386
TRG_ENDOCYTIC_2	47	50	PF00928	0.326
TRG_ER_diArg_1	41	44	PF00400	0.329
TRG_ER_diArg_1	6	8	PF00400	0.497
TRG_NLS_MonoCore_2	93	98	PF00514	0.329
TRG_NLS_MonoExtC_3	166	171	PF00514	0.432
TRG_NLS_MonoExtN_4	93	99	PF00514	0.329
TRG_Pf-PMV_PEXEL_1	48	52	PF00026	0.348

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IMW6	Leptomonas seymouri	78%	100%
A0A0S4J953	Bodo saltans	46%	84%
A0A1X0NUH7	Trypanosomatidae	54%	96%
A0A3R7KF30	Trypanosoma rangeli	49%	96%
A0A3S7X5G7	Leishmania donovani	92%	100%
A4HKD6	Leishmania braziliensis	85%	100%
A4I807	Leishmania infantum	92%	100%
D0AA30	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	51%	94%
E9B2S4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%