LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q5B7_LEIMA
TriTrypDb:
LmjF.32.1635 , LMJLV39_320022500 * , LMJSD75_320022500 *
Length:
250

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q5B7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q5B7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_KEX2_1 111 113 PF00082 0.603
CLV_PCSK_PC1ET2_1 111 113 PF00082 0.603
CLV_PCSK_SKI1_1 27 31 PF00082 0.535
CLV_PCSK_SKI1_1 50 54 PF00082 0.489
CLV_PCSK_SKI1_1 98 102 PF00082 0.679
DEG_APCC_DBOX_1 129 137 PF00400 0.606
DEG_SCF_FBW7_1 207 212 PF00400 0.616
DEG_SCF_FBW7_1 220 227 PF00400 0.542
DEG_SPOP_SBC_1 187 191 PF00917 0.547
DOC_CKS1_1 123 128 PF01111 0.504
DOC_CKS1_1 176 181 PF01111 0.531
DOC_CKS1_1 221 226 PF01111 0.584
DOC_PP4_FxxP_1 123 126 PF00568 0.508
DOC_PP4_FxxP_1 200 203 PF00568 0.628
DOC_USP7_MATH_1 153 157 PF00917 0.631
DOC_USP7_MATH_1 186 190 PF00917 0.623
DOC_USP7_MATH_1 45 49 PF00917 0.574
DOC_USP7_MATH_2 179 185 PF00917 0.604
DOC_USP7_UBL2_3 234 238 PF12436 0.581
DOC_USP7_UBL2_3 245 249 PF12436 0.471
DOC_WW_Pin1_4 122 127 PF00397 0.558
DOC_WW_Pin1_4 156 161 PF00397 0.601
DOC_WW_Pin1_4 175 180 PF00397 0.603
DOC_WW_Pin1_4 188 193 PF00397 0.622
DOC_WW_Pin1_4 195 200 PF00397 0.638
DOC_WW_Pin1_4 205 210 PF00397 0.651
DOC_WW_Pin1_4 220 225 PF00397 0.546
DOC_WW_Pin1_4 37 42 PF00397 0.753
DOC_WW_Pin1_4 65 70 PF00397 0.653
LIG_14-3-3_CanoR_1 130 134 PF00244 0.637
LIG_14-3-3_CanoR_1 155 160 PF00244 0.632
LIG_14-3-3_CanoR_1 182 188 PF00244 0.570
LIG_14-3-3_CanoR_1 67 76 PF00244 0.720
LIG_Actin_WH2_2 95 113 PF00022 0.596
LIG_BIR_II_1 1 5 PF00653 0.514
LIG_BRCT_BRCA1_1 239 243 PF00533 0.456
LIG_BRCT_BRCA1_2 239 245 PF00533 0.456
LIG_FHA_1 167 173 PF00498 0.621
LIG_FHA_1 206 212 PF00498 0.610
LIG_FHA_1 75 81 PF00498 0.568
LIG_FHA_2 176 182 PF00498 0.608
LIG_FHA_2 188 194 PF00498 0.456
LIG_LIR_Apic_2 198 203 PF02991 0.629
LIG_LIR_Gen_1 240 247 PF02991 0.454
LIG_LIR_Nem_3 36 42 PF02991 0.573
LIG_MLH1_MIPbox_1 239 243 PF16413 0.456
LIG_NRP_CendR_1 249 250 PF00754 0.516
LIG_PCNA_PIPBox_1 236 245 PF02747 0.460
LIG_PCNA_yPIPBox_3 234 243 PF02747 0.472
LIG_REV1ctd_RIR_1 240 249 PF16727 0.461
LIG_SH3_3 15 21 PF00018 0.599
LIG_SH3_3 189 195 PF00018 0.562
LIG_SH3_3 201 207 PF00018 0.606
LIG_SH3_3 218 224 PF00018 0.705
LIG_SH3_3 73 79 PF00018 0.599
LIG_SUMO_SIM_anti_2 97 103 PF11976 0.622
LIG_TRAF2_1 162 165 PF00917 0.718
LIG_TRAF2_1 215 218 PF00917 0.553
MOD_CDK_SPxxK_3 175 182 PF00069 0.712
MOD_CDK_SPxxK_3 199 206 PF00069 0.527
MOD_CK1_1 156 162 PF00069 0.577
MOD_CK1_1 168 174 PF00069 0.572
MOD_CK1_1 227 233 PF00069 0.739
MOD_CK1_1 34 40 PF00069 0.544
MOD_CK1_1 48 54 PF00069 0.657
MOD_CK1_1 68 74 PF00069 0.619
MOD_CK2_1 110 116 PF00069 0.643
MOD_CK2_1 175 181 PF00069 0.575
MOD_CK2_1 187 193 PF00069 0.456
MOD_CK2_1 211 217 PF00069 0.646
MOD_CK2_1 29 35 PF00069 0.655
MOD_GlcNHglycan 112 115 PF01048 0.657
MOD_GlcNHglycan 151 154 PF01048 0.712
MOD_GlcNHglycan 211 214 PF01048 0.641
MOD_GlcNHglycan 31 34 PF01048 0.521
MOD_GlcNHglycan 53 56 PF01048 0.597
MOD_GlcNHglycan 70 73 PF01048 0.621
MOD_GSK3_1 149 156 PF00069 0.580
MOD_GSK3_1 171 178 PF00069 0.594
MOD_GSK3_1 195 202 PF00069 0.578
MOD_GSK3_1 205 212 PF00069 0.584
MOD_GSK3_1 216 223 PF00069 0.607
MOD_GSK3_1 237 244 PF00069 0.458
MOD_GSK3_1 29 36 PF00069 0.536
MOD_GSK3_1 46 53 PF00069 0.540
MOD_GSK3_1 55 62 PF00069 0.637
MOD_N-GLC_1 103 108 PF02516 0.514
MOD_NEK2_1 11 16 PF00069 0.589
MOD_NEK2_1 211 216 PF00069 0.650
MOD_PIKK_1 143 149 PF00454 0.549
MOD_PIKK_1 181 187 PF00454 0.521
MOD_PIKK_1 227 233 PF00454 0.562
MOD_PK_1 103 109 PF00069 0.581
MOD_PKA_2 129 135 PF00069 0.641
MOD_PKA_2 181 187 PF00069 0.742
MOD_Plk_1 216 222 PF00069 0.630
MOD_Plk_4 103 109 PF00069 0.653
MOD_Plk_4 171 177 PF00069 0.571
MOD_Plk_4 216 222 PF00069 0.532
MOD_ProDKin_1 122 128 PF00069 0.555
MOD_ProDKin_1 156 162 PF00069 0.599
MOD_ProDKin_1 175 181 PF00069 0.489
MOD_ProDKin_1 188 194 PF00069 0.622
MOD_ProDKin_1 195 201 PF00069 0.639
MOD_ProDKin_1 205 211 PF00069 0.652
MOD_ProDKin_1 220 226 PF00069 0.547
MOD_ProDKin_1 37 43 PF00069 0.757
MOD_ProDKin_1 65 71 PF00069 0.654

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P9J6 Leptomonas seymouri 36% 99%
A0A3S7X5K9 Leishmania donovani 86% 100%
A4I7X8 Leishmania infantum 86% 100%
E9B2T9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 82% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS