LeishMANIAdb
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Paraflagellar_rod_protein_-_putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Paraflagellar_rod_protein_-_putative
Gene product:
Paraflagellar Rod Proteome Component 9, putative
Species:
Leishmania major
UniProt:
Q4Q5B2_LEIMA
TriTrypDb:
LmjF.32.1680 , LMJLV39_320023000 , LMJSD75_320023000 *
Length:
136

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Cellular components
Term Name Level Count
GO:0005929 cilium 4 3
GO:0042995 cell projection 2 3
GO:0043226 organelle 2 3
GO:0043227 membrane-bounded organelle 3 3
GO:0110165 cellular anatomical entity 1 3
GO:0120025 plasma membrane bounded cell projection 3 3
GO:0031514 motile cilium 5 1

Expansion

Sequence features

Q4Q5B2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q5B2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 5 9 PF00656 0.694
CLV_NRD_NRD_1 126 128 PF00675 0.525
CLV_PCSK_FUR_1 64 68 PF00082 0.603
CLV_PCSK_KEX2_1 126 128 PF00082 0.629
CLV_PCSK_KEX2_1 63 65 PF00082 0.613
CLV_PCSK_KEX2_1 66 68 PF00082 0.575
CLV_PCSK_PC1ET2_1 63 65 PF00082 0.613
CLV_PCSK_PC1ET2_1 66 68 PF00082 0.575
CLV_PCSK_SKI1_1 63 67 PF00082 0.551
DEG_Nend_UBRbox_2 1 3 PF02207 0.730
DOC_PP2B_LxvP_1 24 27 PF13499 0.571
LIG_BRCT_BRCA1_1 27 31 PF00533 0.546
LIG_FHA_2 3 9 PF00498 0.699
LIG_Integrin_isoDGR_2 105 107 PF01839 0.570
LIG_LIR_Gen_1 28 39 PF02991 0.555
LIG_LIR_Nem_3 28 34 PF02991 0.552
LIG_SH2_STAT5 73 76 PF00017 0.508
LIG_UBA3_1 88 97 PF00899 0.577
MOD_Cter_Amidation 61 64 PF01082 0.634
MOD_GSK3_1 101 108 PF00069 0.637
MOD_GSK3_1 2 9 PF00069 0.704
MOD_N-GLC_1 6 11 PF02516 0.644
MOD_NEK2_1 121 126 PF00069 0.441
MOD_Plk_1 40 46 PF00069 0.535
MOD_Plk_1 6 12 PF00069 0.644
MOD_Plk_2-3 2 8 PF00069 0.710
MOD_Plk_4 40 46 PF00069 0.542
MOD_SUMO_for_1 65 68 PF00179 0.538
MOD_SUMO_rev_2 58 65 PF00179 0.629
TRG_ER_diArg_1 126 129 PF00400 0.629
TRG_NLS_MonoExtC_3 62 67 PF00514 0.617

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I9A7 Leptomonas seymouri 64% 100%
A0A3Q8IGZ2 Leishmania donovani 95% 100%
A4HKF5 Leishmania braziliensis 68% 100%
A4I7Y3 Leishmania infantum 96% 100%
E9B2U4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 90% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS