Protein SDA1

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Protein SDA1

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q5A0_LEIMA

TriTrypDb:

LmjF.32.1800 , LMJLV39_320024200 , LMJSD75_320024200

Length:

243

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q5A0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q5A0

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	116	120	PF00656	0.645
CLV_C14_Caspase3-7	126	130	PF00656	0.508
CLV_NRD_NRD_1	142	144	PF00675	0.574
CLV_NRD_NRD_1	147	149	PF00675	0.568
CLV_NRD_NRD_1	166	168	PF00675	0.583
CLV_NRD_NRD_1	19	21	PF00675	0.520
CLV_NRD_NRD_1	234	236	PF00675	0.573
CLV_NRD_NRD_1	38	40	PF00675	0.437
CLV_NRD_NRD_1	45	47	PF00675	0.488
CLV_NRD_NRD_1	66	68	PF00675	0.444
CLV_PCSK_FUR_1	35	39	PF00082	0.408
CLV_PCSK_KEX2_1	141	143	PF00082	0.581
CLV_PCSK_KEX2_1	147	149	PF00082	0.562
CLV_PCSK_KEX2_1	166	168	PF00082	0.601
CLV_PCSK_KEX2_1	19	21	PF00082	0.520
CLV_PCSK_KEX2_1	31	33	PF00082	0.482
CLV_PCSK_KEX2_1	37	39	PF00082	0.463
CLV_PCSK_KEX2_1	66	68	PF00082	0.444
CLV_PCSK_PC1ET2_1	31	33	PF00082	0.522
CLV_PCSK_PC1ET2_1	37	39	PF00082	0.592
CLV_PCSK_PC7_1	143	149	PF00082	0.514
CLV_PCSK_SKI1_1	23	27	PF00082	0.466
DEG_Nend_UBRbox_1	1	4	PF02207	0.576
DOC_MAPK_gen_1	26	36	PF00069	0.437
DOC_USP7_MATH_1	12	16	PF00917	0.609
DOC_USP7_MATH_1	204	208	PF00917	0.558
DOC_USP7_MATH_1	238	242	PF00917	0.548
DOC_USP7_MATH_1	99	103	PF00917	0.615
DOC_USP7_UBL2_3	77	81	PF12436	0.595
DOC_WW_Pin1_4	176	181	PF00397	0.569
LIG_14-3-3_CanoR_1	167	173	PF00244	0.582
LIG_14-3-3_CanoR_1	221	230	PF00244	0.636
LIG_BIR_III_4	82	86	PF00653	0.546
LIG_BRCT_BRCA1_1	6	10	PF00533	0.582
LIG_FHA_1	237	243	PF00498	0.550
LIG_FHA_1	28	34	PF00498	0.439
LIG_Pex14_2	230	234	PF04695	0.542
LIG_RPA_C_Fungi	136	148	PF08784	0.572
LIG_SH2_STAT5	63	66	PF00017	0.491
LIG_TRAF2_1	49	52	PF00917	0.487
MOD_CK1_1	110	116	PF00069	0.612
MOD_CK1_1	54	60	PF00069	0.457
MOD_CK2_1	117	123	PF00069	0.577
MOD_CK2_1	12	18	PF00069	0.479
MOD_CK2_1	94	100	PF00069	0.652
MOD_GlcNHglycan	119	122	PF01048	0.647
MOD_GlcNHglycan	202	205	PF01048	0.674
MOD_GlcNHglycan	206	209	PF01048	0.722
MOD_GlcNHglycan	210	213	PF01048	0.629
MOD_GlcNHglycan	95	99	PF01048	0.702
MOD_GSK3_1	113	120	PF00069	0.592
MOD_GSK3_1	200	207	PF00069	0.560
MOD_GSK3_1	222	229	PF00069	0.609
MOD_LATS_1	219	225	PF00433	0.644
MOD_N-GLC_1	222	227	PF02516	0.684
MOD_NEK2_1	27	32	PF00069	0.450
MOD_NEK2_1	59	64	PF00069	0.450
MOD_NEK2_2	238	243	PF00069	0.552
MOD_PKA_2	160	166	PF00069	0.719
MOD_PKA_2	208	214	PF00069	0.709
MOD_Plk_1	110	116	PF00069	0.604
MOD_Plk_1	226	232	PF00069	0.549
MOD_Plk_1	51	57	PF00069	0.473
MOD_Plk_4	59	65	PF00069	0.450
MOD_ProDKin_1	176	182	PF00069	0.571
TRG_ER_diArg_1	141	143	PF00400	0.648
TRG_ER_diArg_1	165	167	PF00400	0.634
TRG_ER_diArg_1	38	40	PF00400	0.406
TRG_ER_diArg_1	65	67	PF00400	0.445
TRG_NLS_Bipartite_1	19	41	PF00514	0.450
TRG_NLS_MonoExtN_4	35	41	PF00514	0.435

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PFN4	Leptomonas seymouri	51%	100%
A0A3Q8IH03	Leishmania donovani	82%	100%
A4HKG7	Leishmania braziliensis	65%	100%
A4I7Z4	Leishmania infantum	86%	100%
E9B2V6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%