CLASP_N domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q583_LEIMA

TriTrypDb:

LmjF.32.1950 , LMJLV39_320026000 , LMJSD75_320026000

Length:

424

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q583

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q583

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	59	63	PF00656	0.609
CLV_NRD_NRD_1	139	141	PF00675	0.508
CLV_NRD_NRD_1	170	172	PF00675	0.458
CLV_NRD_NRD_1	338	340	PF00675	0.616
CLV_NRD_NRD_1	389	391	PF00675	0.632
CLV_NRD_NRD_1	39	41	PF00675	0.567
CLV_NRD_NRD_1	420	422	PF00675	0.612
CLV_NRD_NRD_1	85	87	PF00675	0.721
CLV_PCSK_KEX2_1	170	172	PF00082	0.458
CLV_PCSK_KEX2_1	340	342	PF00082	0.615
CLV_PCSK_KEX2_1	388	390	PF00082	0.628
CLV_PCSK_KEX2_1	39	41	PF00082	0.567
CLV_PCSK_KEX2_1	420	422	PF00082	0.612
CLV_PCSK_PC1ET2_1	340	342	PF00082	0.612
CLV_PCSK_SKI1_1	197	201	PF00082	0.533
CLV_PCSK_SKI1_1	281	285	PF00082	0.395
CLV_PCSK_SKI1_1	390	394	PF00082	0.569
CLV_Separin_Metazoa	204	208	PF03568	0.420
DEG_APCC_DBOX_1	122	130	PF00400	0.547
DEG_Nend_UBRbox_3	1	3	PF02207	0.615
DEG_SPOP_SBC_1	398	402	PF00917	0.603
DOC_CKS1_1	333	338	PF01111	0.603
DOC_MAPK_gen_1	121	130	PF00069	0.548
DOC_MAPK_MEF2A_6	125	133	PF00069	0.534
DOC_USP7_MATH_1	12	16	PF00917	0.549
DOC_USP7_MATH_1	17	21	PF00917	0.536
DOC_USP7_MATH_1	176	180	PF00917	0.432
DOC_USP7_MATH_1	252	256	PF00917	0.396
DOC_USP7_MATH_1	361	365	PF00917	0.593
DOC_USP7_MATH_1	78	82	PF00917	0.566
DOC_USP7_UBL2_3	27	31	PF12436	0.585
DOC_USP7_UBL2_3	340	344	PF12436	0.615
DOC_WW_Pin1_4	316	321	PF00397	0.572
DOC_WW_Pin1_4	332	337	PF00397	0.541
DOC_WW_Pin1_4	382	387	PF00397	0.550
LIG_14-3-3_CanoR_1	149	156	PF00244	0.531
LIG_14-3-3_CanoR_1	230	240	PF00244	0.523
LIG_14-3-3_CanoR_1	332	336	PF00244	0.617
LIG_14-3-3_CanoR_1	360	370	PF00244	0.654
LIG_14-3-3_CanoR_1	389	398	PF00244	0.618
LIG_14-3-3_CanoR_1	405	409	PF00244	0.573
LIG_14-3-3_CanoR_1	98	102	PF00244	0.638
LIG_Actin_WH2_2	124	142	PF00022	0.469
LIG_BIR_III_4	62	66	PF00653	0.601
LIG_EH1_1	272	280	PF00400	0.386
LIG_FHA_1	323	329	PF00498	0.621
LIG_FHA_1	341	347	PF00498	0.559
LIG_FHA_2	102	108	PF00498	0.596
LIG_FHA_2	122	128	PF00498	0.440
LIG_FHA_2	198	204	PF00498	0.460
LIG_FHA_2	347	353	PF00498	0.589
LIG_LIR_Apic_2	90	96	PF02991	0.580
LIG_LIR_Gen_1	175	185	PF02991	0.501
LIG_LIR_Gen_1	282	291	PF02991	0.438
LIG_LIR_Nem_3	175	180	PF02991	0.456
LIG_LIR_Nem_3	227	232	PF02991	0.515
LIG_LIR_Nem_3	282	288	PF02991	0.492
LIG_LIR_Nem_3	45	50	PF02991	0.569
LIG_NRBOX	125	131	PF00104	0.551
LIG_NRBOX	212	218	PF00104	0.391
LIG_NRP_CendR_1	421	424	PF00754	0.610
LIG_Pex14_1	245	249	PF04695	0.426
LIG_SH2_NCK_1	299	303	PF00017	0.550
LIG_SH2_PTP2	285	288	PF00017	0.392
LIG_SH2_PTP2	93	96	PF00017	0.541
LIG_SH2_SRC	93	96	PF00017	0.592
LIG_SH2_STAT5	285	288	PF00017	0.456
LIG_SH2_STAT5	299	302	PF00017	0.650
LIG_SH2_STAT5	93	96	PF00017	0.700
LIG_SH3_3	330	336	PF00018	0.610
LIG_SH3_3	366	372	PF00018	0.606
LIG_SH3_5	154	158	PF00018	0.435
LIG_WRC_WIRS_1	177	182	PF05994	0.517
MOD_CDK_SPxK_1	382	388	PF00069	0.554
MOD_CDK_SPxxK_3	332	339	PF00069	0.606
MOD_CDK_SPxxK_3	382	389	PF00069	0.555
MOD_CK1_1	115	121	PF00069	0.605
MOD_CK1_1	331	337	PF00069	0.626
MOD_CK1_1	384	390	PF00069	0.625
MOD_CK1_1	404	410	PF00069	0.576
MOD_CK1_1	56	62	PF00069	0.615
MOD_CK2_1	101	107	PF00069	0.599
MOD_CK2_1	121	127	PF00069	0.442
MOD_CK2_1	176	182	PF00069	0.506
MOD_CK2_1	346	352	PF00069	0.597
MOD_CK2_1	51	57	PF00069	0.623
MOD_DYRK1A_RPxSP_1	332	336	PF00069	0.573
MOD_GlcNHglycan	300	303	PF01048	0.621
MOD_GSK3_1	111	118	PF00069	0.484
MOD_GSK3_1	248	255	PF00069	0.366
MOD_GSK3_1	328	335	PF00069	0.629
MOD_GSK3_1	342	349	PF00069	0.548
MOD_GSK3_1	361	368	PF00069	0.558
MOD_GSK3_1	376	383	PF00069	0.565
MOD_GSK3_1	397	404	PF00069	0.625
MOD_GSK3_1	52	59	PF00069	0.572
MOD_GSK3_1	97	104	PF00069	0.583
MOD_N-GLC_1	390	395	PF02516	0.597
MOD_N-GLC_1	398	403	PF02516	0.583
MOD_NEK2_1	111	116	PF00069	0.591
MOD_NEK2_1	232	237	PF00069	0.441
MOD_NEK2_1	328	333	PF00069	0.632
MOD_NEK2_1	380	385	PF00069	0.560
MOD_NEK2_1	403	408	PF00069	0.616
MOD_PIKK_1	112	118	PF00454	0.554
MOD_PIKK_1	12	18	PF00454	0.549
MOD_PIKK_1	239	245	PF00454	0.433
MOD_PIKK_1	314	320	PF00454	0.744
MOD_PKA_1	340	346	PF00069	0.599
MOD_PKA_2	148	154	PF00069	0.553
MOD_PKA_2	328	334	PF00069	0.659
MOD_PKA_2	340	346	PF00069	0.602
MOD_PKA_2	359	365	PF00069	0.540
MOD_PKA_2	404	410	PF00069	0.618
MOD_PKA_2	97	103	PF00069	0.551
MOD_PKB_1	388	396	PF00069	0.580
MOD_Plk_1	106	112	PF00069	0.567
MOD_Plk_1	398	404	PF00069	0.607
MOD_Plk_4	106	112	PF00069	0.549
MOD_Plk_4	365	371	PF00069	0.615
MOD_Plk_4	42	48	PF00069	0.562
MOD_Plk_4	97	103	PF00069	0.711
MOD_ProDKin_1	316	322	PF00069	0.570
MOD_ProDKin_1	332	338	PF00069	0.542
MOD_ProDKin_1	382	388	PF00069	0.554
MOD_SUMO_for_1	30	33	PF00179	0.589
MOD_SUMO_rev_2	406	415	PF00179	0.582
TRG_DiLeu_BaEn_1	107	112	PF01217	0.564
TRG_DiLeu_BaEn_4	79	85	PF01217	0.569
TRG_ENDOCYTIC_2	285	288	PF00928	0.484
TRG_ENDOCYTIC_2	47	50	PF00928	0.600
TRG_ER_diArg_1	122	125	PF00400	0.543
TRG_ER_diArg_1	169	171	PF00400	0.454
TRG_ER_diArg_1	388	390	PF00400	0.578
TRG_ER_diArg_1	419	421	PF00400	0.608
TRG_NES_CRM1_1	120	135	PF08389	0.541
TRG_Pf-PMV_PEXEL_1	171	175	PF00026	0.451

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HKI4	Leishmania braziliensis	52%	94%
E9B2X3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	76%	99%