Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q579_LEIMA

TriTrypDb:

LmjF.32.1975 , LMJLV39_320026500 , LMJSD75_320026500

Length:

150

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q579

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q579

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	147	149	PF00675	0.545
CLV_NRD_NRD_1	30	32	PF00675	0.626
CLV_NRD_NRD_1	60	62	PF00675	0.611
CLV_PCSK_FUR_1	6	10	PF00082	0.533
CLV_PCSK_KEX2_1	104	106	PF00082	0.700
CLV_PCSK_KEX2_1	146	148	PF00082	0.565
CLV_PCSK_KEX2_1	29	31	PF00082	0.575
CLV_PCSK_KEX2_1	34	36	PF00082	0.621
CLV_PCSK_KEX2_1	59	61	PF00082	0.610
CLV_PCSK_KEX2_1	8	10	PF00082	0.533
CLV_PCSK_PC1ET2_1	104	106	PF00082	0.700
CLV_PCSK_PC1ET2_1	146	148	PF00082	0.598
CLV_PCSK_PC1ET2_1	29	31	PF00082	0.575
CLV_PCSK_PC1ET2_1	34	36	PF00082	0.621
CLV_PCSK_PC1ET2_1	59	61	PF00082	0.635
CLV_PCSK_PC1ET2_1	8	10	PF00082	0.533
CLV_PCSK_PC7_1	30	36	PF00082	0.605
CLV_PCSK_SKI1_1	143	147	PF00082	0.590
DOC_USP7_MATH_1	64	68	PF00917	0.796
DOC_USP7_UBL2_3	142	146	PF12436	0.564
DOC_USP7_UBL2_3	4	8	PF12436	0.535
DOC_WW_Pin1_4	82	87	PF00397	0.769
LIG_14-3-3_CanoR_1	105	113	PF00244	0.646
LIG_14-3-3_CanoR_1	60	66	PF00244	0.787
LIG_14-3-3_CterR_2	147	150	PF00244	0.488
LIG_BIR_III_2	128	132	PF00653	0.690
LIG_FHA_1	132	138	PF00498	0.630
LIG_FHA_2	37	43	PF00498	0.775
LIG_LIR_Gen_1	110	121	PF02991	0.680
LIG_LIR_Nem_3	110	116	PF02991	0.605
LIG_SH2_STAT5	12	15	PF00017	0.517
LIG_SH2_STAT5	26	29	PF00017	0.540
MOD_CK1_1	107	113	PF00069	0.631
MOD_CK1_1	120	126	PF00069	0.496
MOD_CK1_1	36	42	PF00069	0.769
MOD_CK2_1	109	115	PF00069	0.636
MOD_CK2_1	36	42	PF00069	0.707
MOD_GlcNHglycan	101	104	PF01048	0.549
MOD_GlcNHglycan	119	122	PF01048	0.643
MOD_GlcNHglycan	133	137	PF01048	0.593
MOD_GlcNHglycan	53	56	PF01048	0.593
MOD_GlcNHglycan	70	73	PF01048	0.798
MOD_GlcNHglycan	93	96	PF01048	0.668
MOD_GSK3_1	120	127	PF00069	0.748
MOD_GSK3_1	132	139	PF00069	0.626
MOD_GSK3_1	29	36	PF00069	0.508
MOD_GSK3_1	64	71	PF00069	0.676
MOD_GSK3_1	84	91	PF00069	0.689
MOD_NEK2_2	141	146	PF00069	0.647
MOD_PKA_1	104	110	PF00069	0.634
MOD_PKA_1	29	35	PF00069	0.505
MOD_PKA_1	59	65	PF00069	0.736
MOD_PKA_2	104	110	PF00069	0.634
MOD_PKA_2	131	137	PF00069	0.658
MOD_PKA_2	22	28	PF00069	0.609
MOD_PKA_2	29	35	PF00069	0.679
MOD_PKA_2	36	42	PF00069	0.716
MOD_PKA_2	59	65	PF00069	0.736
MOD_PKB_1	49	57	PF00069	0.562
MOD_Plk_1	132	138	PF00069	0.683
MOD_Plk_4	22	28	PF00069	0.609
MOD_ProDKin_1	82	88	PF00069	0.768
TRG_NLS_MonoCore_2	57	62	PF00514	0.719
TRG_NLS_MonoExtC_3	57	63	PF00514	0.672
TRG_NLS_MonoExtN_4	143	150	PF00514	0.651
TRG_NLS_MonoExtN_4	2	7	PF00514	0.560
TRG_NLS_MonoExtN_4	57	62	PF00514	0.652
TRG_Pf-PMV_PEXEL_1	17	22	PF00026	0.561

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HXV1	Leptomonas seymouri	45%	100%
A0A1X0NU88	Trypanosomatidae	45%	100%
A0A3Q8IJB3	Leishmania donovani	87%	100%
A4HKI7	Leishmania braziliensis	63%	100%
A4I819	Leishmania infantum	87%	100%
D0AA85	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
E9B2X7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	100%