LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q577_LEIMA
TriTrypDb:
LmjF.32.1990 , LMJLV39_320026700 * , LMJSD75_320026800
Length:
111

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q577
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q577

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 107 109 PF00675 0.673
CLV_NRD_NRD_1 38 40 PF00675 0.672
CLV_NRD_NRD_1 70 72 PF00675 0.632
CLV_PCSK_KEX2_1 107 109 PF00082 0.673
CLV_PCSK_KEX2_1 14 16 PF00082 0.638
CLV_PCSK_KEX2_1 70 72 PF00082 0.632
CLV_PCSK_PC1ET2_1 14 16 PF00082 0.638
DOC_ANK_TNKS_1 70 77 PF00023 0.644
DOC_USP7_MATH_1 102 106 PF00917 0.533
LIG_BIR_II_1 1 5 PF00653 0.694
LIG_LIR_Apic_2 99 104 PF02991 0.626
LIG_PROFILIN_1 92 98 PF00235 0.604
LIG_SH2_CRK 101 105 PF00017 0.626
LIG_SH2_NCK_1 101 105 PF00017 0.626
LIG_SH3_1 90 96 PF00018 0.605
LIG_SH3_3 44 50 PF00018 0.545
LIG_SH3_3 6 12 PF00018 0.764
LIG_SH3_3 89 95 PF00018 0.650
LIG_WW_2 95 98 PF00397 0.596
MOD_CK1_1 48 54 PF00069 0.569
MOD_GlcNHglycan 32 35 PF01048 0.637
MOD_PIKK_1 48 54 PF00454 0.646
TRG_ER_diArg_1 106 108 PF00400 0.600
TRG_ER_diArg_1 17 20 PF00400 0.645
TRG_ER_diArg_1 69 71 PF00400 0.632

Homologs

Protein Taxonomy Sequence identity Coverage
A0A3S7X5P3 Leishmania donovani 74% 88%
A4HKI9 Leishmania braziliensis 70% 100%
A4I821 Leishmania infantum 78% 92%
E9B2X9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 82% 100%

Download

Download
LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS