LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania major
UniProt:
Q4Q553_LEIMA
TriTrypDb:
LmjF.32.2220 , LMJLV39_000006200 * , LMJLV39_320029100 * , LMJSD75_320029200 *
Length:
1389

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. yes yes: 10
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q553
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1075 1079 PF00656 0.461
CLV_C14_Caspase3-7 437 441 PF00656 0.543
CLV_C14_Caspase3-7 911 915 PF00656 0.600
CLV_C14_Caspase3-7 974 978 PF00656 0.614
CLV_NRD_NRD_1 1290 1292 PF00675 0.548
CLV_NRD_NRD_1 1331 1333 PF00675 0.481
CLV_NRD_NRD_1 1357 1359 PF00675 0.495
CLV_NRD_NRD_1 197 199 PF00675 0.479
CLV_NRD_NRD_1 446 448 PF00675 0.534
CLV_NRD_NRD_1 740 742 PF00675 0.609
CLV_NRD_NRD_1 887 889 PF00675 0.439
CLV_NRD_NRD_1 940 942 PF00675 0.590
CLV_NRD_NRD_1 979 981 PF00675 0.503
CLV_PCSK_FUR_1 964 968 PF00082 0.520
CLV_PCSK_KEX2_1 1071 1073 PF00082 0.570
CLV_PCSK_KEX2_1 1330 1332 PF00082 0.544
CLV_PCSK_KEX2_1 1357 1359 PF00082 0.495
CLV_PCSK_KEX2_1 158 160 PF00082 0.658
CLV_PCSK_KEX2_1 388 390 PF00082 0.645
CLV_PCSK_KEX2_1 740 742 PF00082 0.609
CLV_PCSK_KEX2_1 826 828 PF00082 0.447
CLV_PCSK_KEX2_1 949 951 PF00082 0.662
CLV_PCSK_KEX2_1 966 968 PF00082 0.434
CLV_PCSK_PC1ET2_1 1071 1073 PF00082 0.605
CLV_PCSK_PC1ET2_1 158 160 PF00082 0.658
CLV_PCSK_PC1ET2_1 388 390 PF00082 0.645
CLV_PCSK_PC1ET2_1 826 828 PF00082 0.447
CLV_PCSK_PC1ET2_1 949 951 PF00082 0.661
CLV_PCSK_PC1ET2_1 966 968 PF00082 0.401
CLV_PCSK_SKI1_1 1105 1109 PF00082 0.584
CLV_PCSK_SKI1_1 1115 1119 PF00082 0.394
CLV_PCSK_SKI1_1 158 162 PF00082 0.555
CLV_PCSK_SKI1_1 41 45 PF00082 0.622
CLV_PCSK_SKI1_1 918 922 PF00082 0.516
CLV_PCSK_SKI1_1 958 962 PF00082 0.509
CLV_PCSK_SKI1_1 980 984 PF00082 0.612
CLV_PCSK_SKI1_1 995 999 PF00082 0.575
DEG_APCC_DBOX_1 1104 1112 PF00400 0.501
DEG_APCC_DBOX_1 1114 1122 PF00400 0.395
DEG_APCC_DBOX_1 158 166 PF00400 0.497
DEG_APCC_DBOX_1 200 208 PF00400 0.552
DEG_APCC_DBOX_1 481 489 PF00400 0.469
DEG_APCC_DBOX_1 940 948 PF00400 0.581
DOC_CYCLIN_RxL_1 386 395 PF00134 0.538
DOC_CYCLIN_RxL_1 977 984 PF00134 0.476
DOC_MAPK_gen_1 877 886 PF00069 0.414
DOC_MAPK_MEF2A_6 18 26 PF00069 0.493
DOC_MAPK_RevD_3 812 827 PF00069 0.437
DOC_MAPK_RevD_3 873 889 PF00069 0.450
DOC_MIT_MIM_1 560 571 PF04212 0.636
DOC_MIT_MIM_1 610 621 PF04212 0.625
DOC_MIT_MIM_1 660 671 PF04212 0.638
DOC_MIT_MIM_1 710 721 PF04212 0.630
DOC_PP1_RVXF_1 784 790 PF00149 0.422
DOC_PP4_FxxP_1 1310 1313 PF00568 0.565
DOC_USP7_MATH_1 1008 1012 PF00917 0.680
DOC_USP7_MATH_1 101 105 PF00917 0.720
DOC_USP7_MATH_1 114 118 PF00917 0.564
DOC_USP7_MATH_1 1144 1148 PF00917 0.541
DOC_USP7_MATH_1 1162 1166 PF00917 0.457
DOC_USP7_MATH_1 1257 1261 PF00917 0.516
DOC_USP7_MATH_1 1302 1306 PF00917 0.492
DOC_USP7_MATH_1 333 337 PF00917 0.671
DOC_USP7_MATH_1 39 43 PF00917 0.572
DOC_USP7_MATH_1 549 553 PF00917 0.639
DOC_USP7_MATH_1 599 603 PF00917 0.646
DOC_USP7_MATH_1 649 653 PF00917 0.700
DOC_USP7_MATH_1 699 703 PF00917 0.728
DOC_USP7_MATH_1 837 841 PF00917 0.513
DOC_USP7_UBL2_3 422 426 PF12436 0.536
DOC_USP7_UBL2_3 854 858 PF12436 0.521
DOC_USP7_UBL2_3 865 869 PF12436 0.524
DOC_USP7_UBL2_3 904 908 PF12436 0.716
DOC_WW_Pin1_4 106 111 PF00397 0.667
DOC_WW_Pin1_4 1142 1147 PF00397 0.570
DOC_WW_Pin1_4 1212 1217 PF00397 0.476
DOC_WW_Pin1_4 1252 1257 PF00397 0.674
DOC_WW_Pin1_4 1309 1314 PF00397 0.607
DOC_WW_Pin1_4 1382 1387 PF00397 0.585
DOC_WW_Pin1_4 173 178 PF00397 0.608
DOC_WW_Pin1_4 280 285 PF00397 0.660
DOC_WW_Pin1_4 5 10 PF00397 0.569
DOC_WW_Pin1_4 63 68 PF00397 0.448
LIG_14-3-3_CanoR_1 1083 1089 PF00244 0.546
LIG_14-3-3_CanoR_1 1115 1125 PF00244 0.493
LIG_14-3-3_CanoR_1 1282 1286 PF00244 0.525
LIG_14-3-3_CanoR_1 1291 1297 PF00244 0.500
LIG_14-3-3_CanoR_1 1301 1307 PF00244 0.436
LIG_14-3-3_CanoR_1 1330 1338 PF00244 0.566
LIG_14-3-3_CanoR_1 1357 1362 PF00244 0.557
LIG_14-3-3_CanoR_1 1377 1387 PF00244 0.533
LIG_14-3-3_CanoR_1 247 254 PF00244 0.479
LIG_14-3-3_CanoR_1 41 51 PF00244 0.567
LIG_14-3-3_CanoR_1 548 556 PF00244 0.677
LIG_14-3-3_CanoR_1 571 575 PF00244 0.698
LIG_14-3-3_CanoR_1 598 606 PF00244 0.784
LIG_14-3-3_CanoR_1 621 625 PF00244 0.630
LIG_14-3-3_CanoR_1 648 656 PF00244 0.607
LIG_14-3-3_CanoR_1 671 675 PF00244 0.721
LIG_14-3-3_CanoR_1 698 706 PF00244 0.675
LIG_14-3-3_CanoR_1 721 725 PF00244 0.688
LIG_14-3-3_CanoR_1 879 886 PF00244 0.446
LIG_14-3-3_CanoR_1 980 989 PF00244 0.557
LIG_Actin_WH2_2 799 817 PF00022 0.539
LIG_APCC_ABBA_1 456 461 PF00400 0.544
LIG_BIR_II_1 1 5 PF00653 0.544
LIG_BRCT_BRCA1_1 1 5 PF00533 0.413
LIG_CaM_IQ_9 218 233 PF13499 0.520
LIG_FHA_1 1085 1091 PF00498 0.616
LIG_FHA_1 1148 1154 PF00498 0.581
LIG_FHA_1 1213 1219 PF00498 0.464
LIG_FHA_1 1306 1312 PF00498 0.406
LIG_FHA_1 1368 1374 PF00498 0.488
LIG_FHA_1 239 245 PF00498 0.471
LIG_FHA_1 369 375 PF00498 0.571
LIG_FHA_1 42 48 PF00498 0.621
LIG_FHA_1 809 815 PF00498 0.593
LIG_FHA_1 879 885 PF00498 0.568
LIG_FHA_2 1046 1052 PF00498 0.600
LIG_FHA_2 1285 1291 PF00498 0.581
LIG_FHA_2 342 348 PF00498 0.749
LIG_FHA_2 463 469 PF00498 0.572
LIG_FHA_2 542 548 PF00498 0.651
LIG_FHA_2 592 598 PF00498 0.680
LIG_FHA_2 642 648 PF00498 0.607
LIG_FHA_2 692 698 PF00498 0.672
LIG_FHA_2 703 709 PF00498 0.577
LIG_FHA_2 968 974 PF00498 0.631
LIG_LIR_Apic_2 1308 1313 PF02991 0.554
LIG_LIR_Gen_1 1175 1184 PF02991 0.557
LIG_LIR_Gen_1 308 315 PF02991 0.524
LIG_LIR_Gen_1 58 68 PF02991 0.454
LIG_LIR_Nem_3 1335 1341 PF02991 0.545
LIG_LIR_Nem_3 1343 1349 PF02991 0.585
LIG_LIR_Nem_3 1359 1364 PF02991 0.488
LIG_LIR_Nem_3 308 313 PF02991 0.532
LIG_LIR_Nem_3 58 63 PF02991 0.459
LIG_MYND_3 1126 1130 PF01753 0.536
LIG_PCNA_yPIPBox_3 1052 1060 PF02747 0.609
LIG_PTAP_UEV_1 1145 1150 PF05743 0.459
LIG_PTB_Apo_2 27 34 PF02174 0.469
LIG_PTB_Phospho_1 27 33 PF10480 0.467
LIG_SH2_CRK 1195 1199 PF00017 0.438
LIG_SH2_CRK 1346 1350 PF00017 0.527
LIG_SH2_STAT5 1324 1327 PF00017 0.462
LIG_SH2_STAT5 304 307 PF00017 0.588
LIG_SH2_STAT5 60 63 PF00017 0.453
LIG_SH2_STAT5 87 90 PF00017 0.477
LIG_SH3_2 1384 1389 PF14604 0.590
LIG_SH3_3 1143 1149 PF00018 0.465
LIG_SH3_3 1250 1256 PF00018 0.531
LIG_SH3_3 1381 1387 PF00018 0.582
LIG_SUMO_SIM_anti_2 1220 1225 PF11976 0.399
LIG_SUMO_SIM_par_1 1217 1222 PF11976 0.490
LIG_SUMO_SIM_par_1 1369 1376 PF11976 0.501
LIG_SUMO_SIM_par_1 179 187 PF11976 0.516
LIG_TRAF2_1 1013 1016 PF00917 0.418
LIG_TRAF2_1 1155 1158 PF00917 0.550
LIG_TRAF2_1 143 146 PF00917 0.576
LIG_TRAF2_1 164 167 PF00917 0.637
LIG_TRAF2_1 249 252 PF00917 0.508
LIG_TRAF2_1 344 347 PF00917 0.583
LIG_TRAF2_1 555 558 PF00917 0.654
LIG_TRAF2_1 605 608 PF00917 0.663
LIG_TRAF2_1 655 658 PF00917 0.634
LIG_TRAF2_1 705 708 PF00917 0.653
LIG_TRAF2_1 909 912 PF00917 0.546
LIG_TYR_ITIM 1193 1198 PF00017 0.419
LIG_UBA3_1 453 457 PF00899 0.529
LIG_WW_3 299 303 PF00397 0.581
MOD_CDC14_SPxK_1 66 69 PF00782 0.452
MOD_CDK_SPxK_1 63 69 PF00069 0.449
MOD_CDK_SPxxK_3 1382 1389 PF00069 0.585
MOD_CK1_1 104 110 PF00069 0.655
MOD_CK1_1 113 119 PF00069 0.590
MOD_CK1_1 1147 1153 PF00069 0.625
MOD_CK1_1 1212 1218 PF00069 0.469
MOD_CK1_1 1260 1266 PF00069 0.514
MOD_CK1_1 1295 1301 PF00069 0.613
MOD_CK1_1 1305 1311 PF00069 0.512
MOD_CK1_1 1322 1328 PF00069 0.450
MOD_CK1_1 278 284 PF00069 0.700
MOD_CK1_1 42 48 PF00069 0.599
MOD_CK1_1 518 524 PF00069 0.553
MOD_CK1_1 702 708 PF00069 0.621
MOD_CK2_1 1045 1051 PF00069 0.686
MOD_CK2_1 1107 1113 PF00069 0.392
MOD_CK2_1 1148 1154 PF00069 0.666
MOD_CK2_1 126 132 PF00069 0.547
MOD_CK2_1 1369 1375 PF00069 0.474
MOD_CK2_1 246 252 PF00069 0.518
MOD_CK2_1 341 347 PF00069 0.689
MOD_CK2_1 551 557 PF00069 0.621
MOD_CK2_1 601 607 PF00069 0.630
MOD_CK2_1 651 657 PF00069 0.629
MOD_CK2_1 701 707 PF00069 0.745
MOD_CK2_1 906 912 PF00069 0.554
MOD_CK2_1 967 973 PF00069 0.567
MOD_GlcNHglycan 1118 1121 PF01048 0.459
MOD_GlcNHglycan 1146 1149 PF01048 0.548
MOD_GlcNHglycan 1150 1153 PF01048 0.535
MOD_GlcNHglycan 1164 1167 PF01048 0.462
MOD_GlcNHglycan 1186 1189 PF01048 0.553
MOD_GlcNHglycan 1211 1214 PF01048 0.518
MOD_GlcNHglycan 1267 1270 PF01048 0.520
MOD_GlcNHglycan 1304 1307 PF01048 0.581
MOD_GlcNHglycan 132 135 PF01048 0.605
MOD_GlcNHglycan 1320 1324 PF01048 0.500
MOD_GlcNHglycan 1327 1330 PF01048 0.536
MOD_GlcNHglycan 285 288 PF01048 0.670
MOD_GlcNHglycan 553 556 PF01048 0.567
MOD_GlcNHglycan 560 563 PF01048 0.653
MOD_GlcNHglycan 603 606 PF01048 0.650
MOD_GlcNHglycan 610 613 PF01048 0.594
MOD_GlcNHglycan 63 66 PF01048 0.518
MOD_GlcNHglycan 653 656 PF01048 0.643
MOD_GlcNHglycan 660 663 PF01048 0.593
MOD_GlcNHglycan 710 713 PF01048 0.578
MOD_GlcNHglycan 831 834 PF01048 0.511
MOD_GlcNHglycan 84 87 PF01048 0.553
MOD_GlcNHglycan 92 96 PF01048 0.532
MOD_GSK3_1 1 8 PF00069 0.508
MOD_GSK3_1 101 108 PF00069 0.726
MOD_GSK3_1 1084 1091 PF00069 0.622
MOD_GSK3_1 109 116 PF00069 0.799
MOD_GSK3_1 1144 1151 PF00069 0.578
MOD_GSK3_1 1229 1236 PF00069 0.397
MOD_GSK3_1 126 133 PF00069 0.585
MOD_GSK3_1 1301 1308 PF00069 0.583
MOD_GSK3_1 1318 1325 PF00069 0.484
MOD_GSK3_1 1378 1385 PF00069 0.490
MOD_GSK3_1 275 282 PF00069 0.672
MOD_GSK3_1 518 525 PF00069 0.572
MOD_GSK3_1 52 59 PF00069 0.458
MOD_GSK3_1 898 905 PF00069 0.561
MOD_LATS_1 1299 1305 PF00433 0.514
MOD_LATS_1 993 999 PF00433 0.424
MOD_N-GLC_1 110 115 PF02516 0.694
MOD_N-GLC_1 1257 1262 PF02516 0.539
MOD_N-GLC_1 278 283 PF02516 0.586
MOD_N-GLC_1 478 483 PF02516 0.458
MOD_N-GLC_1 518 523 PF02516 0.541
MOD_N-GLC_2 1265 1267 PF02516 0.419
MOD_NEK2_1 1 6 PF00069 0.548
MOD_NEK2_1 1045 1050 PF00069 0.522
MOD_NEK2_1 1107 1112 PF00069 0.442
MOD_NEK2_1 1198 1203 PF00069 0.561
MOD_NEK2_1 165 170 PF00069 0.667
MOD_NEK2_1 275 280 PF00069 0.595
MOD_NEK2_1 359 364 PF00069 0.574
MOD_NEK2_1 391 396 PF00069 0.525
MOD_NEK2_1 421 426 PF00069 0.562
MOD_NEK2_1 478 483 PF00069 0.480
MOD_NEK2_1 520 525 PF00069 0.693
MOD_NEK2_1 570 575 PF00069 0.708
MOD_NEK2_1 61 66 PF00069 0.546
MOD_NEK2_1 620 625 PF00069 0.693
MOD_NEK2_1 670 675 PF00069 0.611
MOD_NEK2_1 720 725 PF00069 0.659
MOD_NEK2_1 902 907 PF00069 0.551
MOD_NEK2_1 960 965 PF00069 0.623
MOD_PIKK_1 1167 1173 PF00454 0.489
MOD_PIKK_1 246 252 PF00454 0.508
MOD_PIKK_1 326 332 PF00454 0.634
MOD_PIKK_1 333 339 PF00454 0.581
MOD_PIKK_1 434 440 PF00454 0.731
MOD_PIKK_1 494 500 PF00454 0.578
MOD_PIKK_1 549 555 PF00454 0.637
MOD_PIKK_1 599 605 PF00454 0.685
MOD_PIKK_1 649 655 PF00454 0.615
MOD_PIKK_1 699 705 PF00454 0.657
MOD_PIKK_1 745 751 PF00454 0.624
MOD_PIKK_1 981 987 PF00454 0.448
MOD_PIKK_1 995 1001 PF00454 0.444
MOD_PKA_1 1330 1336 PF00069 0.540
MOD_PKA_1 1357 1363 PF00069 0.560
MOD_PKA_1 966 972 PF00069 0.513
MOD_PKA_2 1088 1094 PF00069 0.541
MOD_PKA_2 1281 1287 PF00069 0.534
MOD_PKA_2 1318 1324 PF00069 0.680
MOD_PKA_2 1330 1336 PF00069 0.602
MOD_PKA_2 1356 1362 PF00069 0.561
MOD_PKA_2 246 252 PF00069 0.481
MOD_PKA_2 331 337 PF00069 0.614
MOD_PKA_2 368 374 PF00069 0.563
MOD_PKA_2 558 564 PF00069 0.631
MOD_PKA_2 570 576 PF00069 0.698
MOD_PKA_2 608 614 PF00069 0.614
MOD_PKA_2 620 626 PF00069 0.580
MOD_PKA_2 658 664 PF00069 0.635
MOD_PKA_2 670 676 PF00069 0.616
MOD_PKA_2 708 714 PF00069 0.628
MOD_PKA_2 720 726 PF00069 0.595
MOD_PKA_2 878 884 PF00069 0.523
MOD_PKA_2 966 972 PF00069 0.513
MOD_Plk_1 1219 1225 PF00069 0.486
MOD_Plk_1 1257 1263 PF00069 0.508
MOD_Plk_1 1319 1325 PF00069 0.446
MOD_Plk_1 478 484 PF00069 0.463
MOD_Plk_1 518 524 PF00069 0.639
MOD_Plk_4 1 7 PF00069 0.420
MOD_Plk_4 1088 1094 PF00069 0.458
MOD_Plk_4 114 120 PF00069 0.603
MOD_Plk_4 1219 1225 PF00069 0.475
MOD_Plk_4 1292 1298 PF00069 0.524
MOD_Plk_4 449 455 PF00069 0.559
MOD_Plk_4 56 62 PF00069 0.427
MOD_ProDKin_1 106 112 PF00069 0.665
MOD_ProDKin_1 1142 1148 PF00069 0.567
MOD_ProDKin_1 1212 1218 PF00069 0.467
MOD_ProDKin_1 1252 1258 PF00069 0.670
MOD_ProDKin_1 1309 1315 PF00069 0.609
MOD_ProDKin_1 1382 1388 PF00069 0.586
MOD_ProDKin_1 173 179 PF00069 0.609
MOD_ProDKin_1 280 286 PF00069 0.665
MOD_ProDKin_1 5 11 PF00069 0.569
MOD_ProDKin_1 63 69 PF00069 0.449
MOD_SUMO_for_1 207 210 PF00179 0.558
MOD_SUMO_for_1 261 264 PF00179 0.501
MOD_SUMO_for_1 806 809 PF00179 0.446
MOD_SUMO_for_1 846 849 PF00179 0.617
MOD_SUMO_for_1 895 898 PF00179 0.507
MOD_SUMO_rev_2 1064 1073 PF00179 0.582
MOD_SUMO_rev_2 1286 1294 PF00179 0.562
MOD_SUMO_rev_2 152 160 PF00179 0.646
MOD_SUMO_rev_2 249 255 PF00179 0.516
MOD_SUMO_rev_2 264 270 PF00179 0.504
MOD_SUMO_rev_2 429 437 PF00179 0.535
MOD_SUMO_rev_2 440 450 PF00179 0.513
MOD_SUMO_rev_2 790 795 PF00179 0.467
MOD_SUMO_rev_2 808 817 PF00179 0.488
MOD_SUMO_rev_2 819 828 PF00179 0.424
TRG_DiLeu_BaEn_1 132 137 PF01217 0.537
TRG_DiLeu_BaEn_1 157 162 PF01217 0.648
TRG_DiLeu_BaEn_4 1375 1381 PF01217 0.545
TRG_DiLeu_BaEn_4 848 854 PF01217 0.473
TRG_ENDOCYTIC_2 1195 1198 PF00928 0.459
TRG_ENDOCYTIC_2 1346 1349 PF00928 0.435
TRG_ENDOCYTIC_2 60 63 PF00928 0.453
TRG_ENDOCYTIC_2 986 989 PF00928 0.597
TRG_ER_diArg_1 1330 1332 PF00400 0.536
TRG_ER_diArg_1 482 485 PF00400 0.453
TRG_ER_diArg_1 740 742 PF00400 0.609
TRG_NLS_MonoExtC_3 1070 1076 PF00514 0.605
TRG_NLS_MonoExtC_3 197 203 PF00514 0.462
TRG_NLS_MonoExtN_4 1068 1075 PF00514 0.598
TRG_Pf-PMV_PEXEL_1 198 203 PF00026 0.635
TRG_Pf-PMV_PEXEL_1 469 473 PF00026 0.454
TRG_Pf-PMV_PEXEL_1 942 946 PF00026 0.520
TRG_Pf-PMV_PEXEL_1 980 985 PF00026 0.511

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I394 Leptomonas seymouri 37% 69%
A0A3S7X5P9 Leishmania donovani 82% 84%
A4HKL2 Leishmania braziliensis 56% 84%
A4I845 Leishmania infantum 77% 89%
E9B303 Leishmania mexicana (strain MHOM/GT/2001/U1103) 76% 90%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS