Putative ATP-dependent RNA helicase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP-dependent RNA helicase, putative

Species:

Leishmania major

UniProt:

Q4Q552_LEIMA

TriTrypDb:

LmjF.32.2230 , LMJLV39_320029200 , LMJSD75_320029300

Length:

773

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005730	nucleolus	5	2
GO:0043226	organelle	2	2
GO:0043228	non-membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043232	intracellular non-membrane-bounded organelle	4	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

Q4Q552

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q552

Function

Biological processes
Term	Name	Level	Count
GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	10	2
GO:0000470	maturation of LSU-rRNA	9	2
GO:0006139	nucleobase-containing compound metabolic process	3	2
GO:0006364	rRNA processing	8	2
GO:0006396	RNA processing	6	2
GO:0006725	cellular aromatic compound metabolic process	3	2
GO:0006807	nitrogen compound metabolic process	2	2
GO:0008152	metabolic process	1	2
GO:0009987	cellular process	1	2
GO:0016070	RNA metabolic process	5	2
GO:0016072	rRNA metabolic process	7	2
GO:0034470	ncRNA processing	7	2
GO:0034641	cellular nitrogen compound metabolic process	3	2
GO:0034660	ncRNA metabolic process	6	2
GO:0043170	macromolecule metabolic process	3	2
GO:0044237	cellular metabolic process	2	2
GO:0044238	primary metabolic process	2	2
GO:0046483	heterocycle metabolic process	3	2
GO:0071704	organic substance metabolic process	2	2
GO:0090304	nucleic acid metabolic process	4	2
GO:1901360	organic cyclic compound metabolic process	3	2

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003723	RNA binding	4	11
GO:0003824	catalytic activity	1	12
GO:0004386	helicase activity	2	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0016787	hydrolase activity	2	12
GO:0017076	purine nucleotide binding	4	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:0140640	catalytic activity, acting on a nucleic acid	2	12
GO:0140657	ATP-dependent activity	1	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	181	185	PF00656	0.714
CLV_C14_Caspase3-7	426	430	PF00656	0.632
CLV_C14_Caspase3-7	435	439	PF00656	0.519
CLV_NRD_NRD_1	105	107	PF00675	0.570
CLV_NRD_NRD_1	109	111	PF00675	0.699
CLV_NRD_NRD_1	170	172	PF00675	0.674
CLV_NRD_NRD_1	197	199	PF00675	0.525
CLV_NRD_NRD_1	333	335	PF00675	0.254
CLV_NRD_NRD_1	470	472	PF00675	0.711
CLV_NRD_NRD_1	520	522	PF00675	0.333
CLV_NRD_NRD_1	6	8	PF00675	0.528
CLV_NRD_NRD_1	727	729	PF00675	0.615
CLV_NRD_NRD_1	742	744	PF00675	0.433
CLV_NRD_NRD_1	88	90	PF00675	0.576
CLV_PCSK_FUR_1	106	110	PF00082	0.768
CLV_PCSK_KEX2_1	107	109	PF00082	0.503
CLV_PCSK_KEX2_1	197	199	PF00082	0.524
CLV_PCSK_KEX2_1	332	334	PF00082	0.262
CLV_PCSK_KEX2_1	520	522	PF00082	0.295
CLV_PCSK_KEX2_1	6	8	PF00082	0.529
CLV_PCSK_KEX2_1	727	729	PF00082	0.577
CLV_PCSK_KEX2_1	741	743	PF00082	0.469
CLV_PCSK_KEX2_1	88	90	PF00082	0.581
CLV_PCSK_PC1ET2_1	107	109	PF00082	0.664
CLV_PCSK_PC1ET2_1	727	729	PF00082	0.583
CLV_PCSK_SKI1_1	143	147	PF00082	0.784
CLV_PCSK_SKI1_1	520	524	PF00082	0.296
DEG_APCC_DBOX_1	363	371	PF00400	0.533
DEG_APCC_DBOX_1	413	421	PF00400	0.533
DEG_APCC_DBOX_1	698	706	PF00400	0.319
DEG_APCC_DBOX_1	740	748	PF00400	0.652
DOC_ANK_TNKS_1	374	381	PF00023	0.451
DOC_CKS1_1	344	349	PF01111	0.451
DOC_CKS1_1	626	631	PF01111	0.385
DOC_CYCLIN_RxL_1	363	374	PF00134	0.442
DOC_MAPK_gen_1	520	527	PF00069	0.493
DOC_MAPK_RevD_3	52	66	PF00069	0.515
DOC_PP1_RVXF_1	254	261	PF00149	0.451
DOC_PP2B_LxvP_1	283	286	PF13499	0.491
DOC_PP2B_LxvP_1	587	590	PF13499	0.451
DOC_PP4_FxxP_1	139	142	PF00568	0.733
DOC_PP4_FxxP_1	206	209	PF00568	0.405
DOC_PP4_FxxP_1	260	263	PF00568	0.451
DOC_PP4_FxxP_1	52	55	PF00568	0.638
DOC_PP4_FxxP_1	626	629	PF00568	0.345
DOC_USP7_MATH_1	113	117	PF00917	0.753
DOC_USP7_MATH_1	403	407	PF00917	0.451
DOC_USP7_MATH_1	442	446	PF00917	0.587
DOC_USP7_MATH_1	490	494	PF00917	0.468
DOC_USP7_MATH_1	590	594	PF00917	0.499
DOC_USP7_MATH_1	685	689	PF00917	0.378
DOC_USP7_UBL2_3	4	8	PF12436	0.532
DOC_USP7_UBL2_3	729	733	PF12436	0.557
DOC_WW_Pin1_4	343	348	PF00397	0.451
DOC_WW_Pin1_4	625	630	PF00397	0.386
LIG_14-3-3_CanoR_1	396	400	PF00244	0.461
LIG_14-3-3_CanoR_1	414	418	PF00244	0.342
LIG_14-3-3_CanoR_1	509	515	PF00244	0.496
LIG_14-3-3_CanoR_1	562	567	PF00244	0.501
LIG_14-3-3_CanoR_1	610	620	PF00244	0.451
LIG_14-3-3_CanoR_1	735	740	PF00244	0.681
LIG_14-3-3_CanoR_1	88	98	PF00244	0.684
LIG_Actin_WH2_2	676	694	PF00022	0.424
LIG_APCC_ABBA_1	566	571	PF00400	0.491
LIG_BIR_III_2	489	493	PF00653	0.551
LIG_BIR_III_4	483	487	PF00653	0.627
LIG_BIR_III_4	57	61	PF00653	0.638
LIG_BRCT_BRCA1_1	532	536	PF00533	0.451
LIG_BRCT_BRCA1_1	542	546	PF00533	0.451
LIG_BRCT_BRCA1_1	622	626	PF00533	0.422
LIG_BRCT_BRCA1_1	66	70	PF00533	0.634
LIG_BRCT_BRCA1_1	705	709	PF00533	0.424
LIG_BRCT_BRCA1_1	767	771	PF00533	0.612
LIG_Clathr_ClatBox_1	210	214	PF01394	0.426
LIG_Clathr_ClatBox_1	367	371	PF01394	0.533
LIG_deltaCOP1_diTrp_1	571	578	PF00928	0.462
LIG_eIF4E_1	133	139	PF01652	0.720
LIG_FHA_1	277	283	PF00498	0.468
LIG_FHA_1	285	291	PF00498	0.464
LIG_FHA_1	292	298	PF00498	0.433
LIG_FHA_1	548	554	PF00498	0.410
LIG_FHA_1	572	578	PF00498	0.427
LIG_FHA_1	603	609	PF00498	0.441
LIG_FHA_1	692	698	PF00498	0.319
LIG_FHA_2	424	430	PF00498	0.596
LIG_FHA_2	626	632	PF00498	0.388
LIG_FHA_2	721	727	PF00498	0.620
LIG_LIR_Apic_2	136	142	PF02991	0.677
LIG_LIR_Apic_2	257	263	PF02991	0.451
LIG_LIR_Apic_2	49	55	PF02991	0.667
LIG_LIR_Apic_2	623	629	PF02991	0.421
LIG_LIR_Apic_2	646	651	PF02991	0.394
LIG_LIR_Gen_1	242	250	PF02991	0.526
LIG_LIR_Gen_1	565	571	PF02991	0.528
LIG_LIR_Nem_3	242	247	PF02991	0.471
LIG_LIR_Nem_3	565	569	PF02991	0.500
LIG_LIR_Nem_3	631	637	PF02991	0.380
LIG_LIR_Nem_3	763	767	PF02991	0.631
LIG_LIR_Nem_3	92	97	PF02991	0.650
LIG_MAD2	43	51	PF02301	0.504
LIG_MLH1_MIPbox_1	66	70	PF16413	0.672
LIG_MYND_1	600	604	PF01753	0.451
LIG_PCNA_PIPBox_1	505	514	PF02747	0.412
LIG_PCNA_yPIPBox_3	375	389	PF02747	0.537
LIG_PCNA_yPIPBox_3	505	516	PF02747	0.412
LIG_PCNA_yPIPBox_3	653	665	PF02747	0.303
LIG_Pex14_1	594	598	PF04695	0.451
LIG_REV1ctd_RIR_1	67	75	PF16727	0.670
LIG_RPA_C_Fungi	193	205	PF08784	0.597
LIG_SH2_CRK	244	248	PF00017	0.303
LIG_SH2_CRK	512	516	PF00017	0.360
LIG_SH2_CRK	598	602	PF00017	0.303
LIG_SH2_PTP2	500	503	PF00017	0.409
LIG_SH2_SRC	598	601	PF00017	0.303
LIG_SH2_STAT5	128	131	PF00017	0.666
LIG_SH2_STAT5	500	503	PF00017	0.434
LIG_SH2_STAT5	512	515	PF00017	0.312
LIG_SH2_STAT5	607	610	PF00017	0.303
LIG_SH2_STAT5	637	640	PF00017	0.409
LIG_SH2_STAT5	731	734	PF00017	0.540
LIG_SH3_1	598	604	PF00018	0.303
LIG_SH3_3	341	347	PF00018	0.303
LIG_SH3_3	598	604	PF00018	0.303
LIG_SH3_3	714	720	PF00018	0.319
LIG_SH3_3	764	770	PF00018	0.643
LIG_SUMO_SIM_anti_2	187	195	PF11976	0.669
LIG_SUMO_SIM_par_1	114	123	PF11976	0.509
LIG_SUMO_SIM_par_1	214	219	PF11976	0.489
LIG_SUMO_SIM_par_1	366	372	PF11976	0.416
LIG_TRAF2_1	628	631	PF00917	0.361
LIG_TRAF2_1	723	726	PF00917	0.569
LIG_UBA3_1	264	269	PF00899	0.371
LIG_WRC_WIRS_1	511	516	PF05994	0.424
LIG_WRC_WIRS_1	563	568	PF05994	0.412
MOD_CDK_SPxK_1	343	349	PF00069	0.303
MOD_CK1_1	155	161	PF00069	0.707
MOD_CK1_1	167	173	PF00069	0.749
MOD_CK1_1	254	260	PF00069	0.303
MOD_CK1_1	296	302	PF00069	0.372
MOD_CK1_1	674	680	PF00069	0.319
MOD_CK2_1	175	181	PF00069	0.665
MOD_CK2_1	405	411	PF00069	0.319
MOD_CK2_1	625	631	PF00069	0.383
MOD_CK2_1	720	726	PF00069	0.564
MOD_Cter_Amidation	4	7	PF01082	0.535
MOD_Cter_Amidation	469	472	PF01082	0.674
MOD_GlcNHglycan	102	105	PF01048	0.722
MOD_GlcNHglycan	146	149	PF01048	0.692
MOD_GlcNHglycan	155	158	PF01048	0.671
MOD_GlcNHglycan	166	169	PF01048	0.735
MOD_GlcNHglycan	253	256	PF01048	0.303
MOD_GlcNHglycan	336	339	PF01048	0.360
MOD_GlcNHglycan	401	404	PF01048	0.303
MOD_GlcNHglycan	443	447	PF01048	0.615
MOD_GlcNHglycan	532	535	PF01048	0.424
MOD_GlcNHglycan	673	676	PF01048	0.305
MOD_GSK3_1	144	151	PF00069	0.726
MOD_GSK3_1	293	300	PF00069	0.359
MOD_GSK3_1	334	341	PF00069	0.412
MOD_GSK3_1	395	402	PF00069	0.300
MOD_GSK3_1	438	445	PF00069	0.601
MOD_GSK3_1	474	481	PF00069	0.594
MOD_GSK3_1	526	533	PF00069	0.303
MOD_GSK3_1	567	574	PF00069	0.415
MOD_GSK3_1	616	623	PF00069	0.512
MOD_N-GLC_1	752	757	PF02516	0.660
MOD_N-GLC_1	760	765	PF02516	0.663
MOD_NEK2_1	399	404	PF00069	0.302
MOD_NEK2_1	415	420	PF00069	0.413
MOD_NEK2_1	423	428	PF00069	0.415
MOD_NEK2_1	527	532	PF00069	0.303
MOD_NEK2_1	540	545	PF00069	0.303
MOD_NEK2_1	709	714	PF00069	0.358
MOD_PIKK_1	501	507	PF00454	0.434
MOD_PIKK_1	89	95	PF00454	0.680
MOD_PKA_1	89	95	PF00069	0.587
MOD_PKA_2	164	170	PF00069	0.780
MOD_PKA_2	227	233	PF00069	0.303
MOD_PKA_2	395	401	PF00069	0.280
MOD_PKA_2	413	419	PF00069	0.415
MOD_PKA_2	720	726	PF00069	0.648
MOD_PKB_1	332	340	PF00069	0.424
MOD_PKB_1	560	568	PF00069	0.412
MOD_Plk_1	113	119	PF00069	0.715
MOD_Plk_1	124	130	PF00069	0.579
MOD_Plk_1	233	239	PF00069	0.424
MOD_Plk_1	360	366	PF00069	0.370
MOD_Plk_1	547	553	PF00069	0.217
MOD_Plk_2-3	429	435	PF00069	0.620
MOD_Plk_2-3	478	484	PF00069	0.763
MOD_Plk_4	113	119	PF00069	0.732
MOD_Plk_4	124	130	PF00069	0.653
MOD_Plk_4	293	299	PF00069	0.370
MOD_Plk_4	338	344	PF00069	0.335
MOD_Plk_4	395	401	PF00069	0.290
MOD_Plk_4	429	435	PF00069	0.552
MOD_Plk_4	510	516	PF00069	0.396
MOD_Plk_4	547	553	PF00069	0.437
MOD_Plk_4	590	596	PF00069	0.388
MOD_Plk_4	620	626	PF00069	0.440
MOD_Plk_4	760	766	PF00069	0.601
MOD_ProDKin_1	343	349	PF00069	0.303
MOD_ProDKin_1	625	631	PF00069	0.383
MOD_SUMO_rev_2	136	145	PF00179	0.567
TRG_DiLeu_BaEn_1	189	194	PF01217	0.673
TRG_DiLeu_BaEn_1	242	247	PF01217	0.339
TRG_DiLeu_BaEn_1	331	336	PF01217	0.318
TRG_DiLeu_BaEn_2	629	635	PF01217	0.371
TRG_DiLeu_BaEn_2	759	765	PF01217	0.628
TRG_DiLeu_BaLyEn_6	206	211	PF01217	0.443
TRG_DiLeu_BaLyEn_6	260	265	PF01217	0.388
TRG_DiLeu_BaLyEn_6	363	368	PF01217	0.418
TRG_ENDOCYTIC_2	244	247	PF00928	0.303
TRG_ENDOCYTIC_2	512	515	PF00928	0.295
TRG_ER_diArg_1	10	13	PF00400	0.551
TRG_ER_diArg_1	106	109	PF00400	0.749
TRG_ER_diArg_1	332	334	PF00400	0.338
TRG_ER_diArg_1	364	367	PF00400	0.338
TRG_ER_diArg_1	560	563	PF00400	0.303
TRG_ER_diArg_1	741	743	PF00400	0.552
TRG_NES_CRM1_1	361	374	PF08389	0.315
TRG_NLS_Bipartite_1	88	110	PF00514	0.716
TRG_NLS_MonoCore_2	105	110	PF00514	0.743
TRG_NLS_MonoExtC_3	105	110	PF00514	0.717
TRG_NLS_MonoExtC_3	6	11	PF00514	0.539
TRG_NLS_MonoExtN_4	106	111	PF00514	0.735
TRG_NLS_MonoExtN_4	4	11	PF00514	0.543
TRG_Pf-PMV_PEXEL_1	366	371	PF00026	0.292
TRG_Pf-PMV_PEXEL_1	375	379	PF00026	0.303

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HWK5	Leptomonas seymouri	74%	98%
A0A0N1I6K5	Leptomonas seymouri	33%	100%
A0A0S4IWD0	Bodo saltans	36%	100%
A0A0S4JSZ9	Bodo saltans	23%	100%
A0A0S4KKU4	Bodo saltans	64%	100%
A0A1X0NVD0	Trypanosomatidae	26%	100%
A0A1X0NVK0	Trypanosomatidae	57%	100%
A0A1X0P7S4	Trypanosomatidae	35%	100%
A0A3Q8ICA8	Leishmania donovani	22%	100%
A0A3R7M1K3	Trypanosoma rangeli	56%	100%
A0A3R7NGQ1	Trypanosoma rangeli	36%	100%
A0A3R7RJV1	Trypanosoma rangeli	26%	100%
A0A3S5H5H4	Leishmania donovani	28%	100%
A0A3S5H6T7	Leishmania donovani	30%	100%
A0A3S7X579	Leishmania donovani	26%	100%
A0A3S7X5R1	Leishmania donovani	95%	100%
A0A3S7XAN8	Leishmania donovani	34%	100%
A1CB55	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	28%	100%
A1CIQ5	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	34%	100%
A1CL59	Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107)	28%	100%
A1CW14	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	33%	100%
A1D699	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	28%	100%
A1DE84	Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)	29%	100%
A2QE29	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	28%	100%
A2RA55	Aspergillus niger (strain CBS 513.88 / FGSC A1513)	29%	100%
A3GGE9	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	31%	100%
A3LNR6	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	33%	100%
A3LWH3	Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545)	28%	100%
A4H481	Leishmania braziliensis	27%	100%
A4H7Y3	Leishmania braziliensis	29%	100%
A4HK38	Leishmania braziliensis	25%	100%
A4HKL3	Leishmania braziliensis	83%	100%
A4HP48	Leishmania braziliensis	36%	100%
A4HSF8	Leishmania infantum	28%	100%
A4HUT1	Leishmania infantum	22%	100%
A4HWB0	Leishmania infantum	30%	100%
A4I7M5	Leishmania infantum	27%	100%
A4I846	Leishmania infantum	95%	100%
A4IDF5	Leishmania infantum	34%	100%
A4R8B5	Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958)	33%	100%
A5DAR2	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	28%	100%
A5DGM4	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	27%	100%
A5DLF4	Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324)	31%	100%
A5E2I8	Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239)	26%	100%
A6RSH5	Botryotinia fuckeliana (strain B05.10)	29%	88%
A6ZPU3	Saccharomyces cerevisiae (strain YJM789)	31%	100%
A6ZZY8	Saccharomyces cerevisiae (strain YJM789)	28%	100%
A7A237	Saccharomyces cerevisiae (strain YJM789)	26%	100%
A7ESL8	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	31%	96%
A7F8V8	Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1)	29%	88%
A7TJ71	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	31%	100%
A7TNT1	Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294 / BCRC 21397 / CBS 2163 / NBRC 10782 / NRRL Y-8283 / UCD 57-17)	27%	100%
D0A6Z3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	23%	100%
D0AAB3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	57%	100%
E9AKE2	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	100%
E9AQ10	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9ASV6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	100%
E9B2I0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	100%
E9B304	Leishmania mexicana (strain MHOM/GT/2001/U1103)	93%	100%
O49289	Arabidopsis thaliana	26%	91%
O60173	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	26%	100%
O74764	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	29%	100%
O80792	Arabidopsis thaliana	27%	91%
P0CQ82	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	31%	90%
P0CQ83	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	31%	90%
P0CQ84	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	36%	100%
P0CQ85	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	36%	100%
P15424	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	27%	100%
P20448	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	31%	100%
P25808	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	26%	100%
P36120	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	100%
Q09916	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	34%	100%
Q0CF43	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	29%	100%
Q0CMM5	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	33%	96%
Q0CQF3	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	28%	100%
Q0CZS8	Aspergillus terreus (strain NIH 2624 / FGSC A1156)	33%	100%
Q0DBS1	Oryza sativa subsp. japonica	31%	100%
Q0DBU5	Oryza sativa subsp. japonica	28%	100%
Q0DLB9	Oryza sativa subsp. japonica	32%	100%
Q0UHM7	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	28%	93%
Q0UMB9	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	31%	96%
Q0UP45	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	29%	100%
Q0UR48	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	33%	100%
Q13206	Homo sapiens	31%	88%
Q1E9T9	Coccidioides immitis (strain RS)	28%	100%
Q1EA54	Coccidioides immitis (strain RS)	33%	100%
Q1EB31	Coccidioides immitis (strain RS)	31%	96%
Q2UE66	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	29%	100%
Q4HZ68	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	28%	100%
Q4IAS1	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	30%	97%
Q4IBS2	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	27%	99%
Q4IEK8	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	33%	100%
Q4P0Y5	Ustilago maydis (strain 521 / FGSC 9021)	27%	79%
Q4P9E5	Ustilago maydis (strain 521 / FGSC 9021)	30%	100%
Q4Q1P0	Leishmania major	34%	100%
Q4Q5M6	Leishmania major	26%	100%
Q4QFH1	Leishmania major	30%	100%
Q4QJG6	Leishmania major	28%	100%
Q4WQM4	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	33%	100%
Q4WV71	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	28%	100%
Q4WYJ7	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	28%	100%
Q54EC2	Dictyostelium discoideum	27%	100%
Q59N29	Candida albicans (strain SC5314 / ATCC MYA-2876)	26%	100%
Q59S50	Candida albicans (strain SC5314 / ATCC MYA-2876)	27%	100%
Q5AF95	Candida albicans (strain SC5314 / ATCC MYA-2876)	30%	100%
Q5AK59	Candida albicans (strain SC5314 / ATCC MYA-2876)	36%	100%
Q5BFU1	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	32%	95%
Q5BGX6	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	30%	99%
Q5ZBH5	Oryza sativa subsp. japonica	28%	100%
Q5ZLN8	Gallus gallus	32%	100%
Q650T9	Oryza sativa subsp. japonica	29%	100%
Q6BH93	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	32%	100%
Q6BKH3	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	27%	97%
Q6BSM3	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	27%	100%
Q6C193	Yarrowia lipolytica (strain CLIB 122 / E 150)	28%	100%
Q6C835	Yarrowia lipolytica (strain CLIB 122 / E 150)	30%	97%
Q6CGD1	Yarrowia lipolytica (strain CLIB 122 / E 150)	31%	100%
Q6CK32	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	29%	100%
Q6CRF4	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	33%	100%
Q6FKS8	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	26%	100%
Q6FNA2	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	29%	80%
Q6FPT7	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	32%	100%
Q6NZQ2	Mus musculus	31%	100%
Q754J2	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	28%	100%
Q75C76	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	33%	100%
Q7RZ35	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	31%	94%
Q7S2N9	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	32%	100%
Q7S5R1	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	27%	100%
Q7XJN0	Arabidopsis thaliana	32%	100%
Q80Y44	Mus musculus	28%	88%
Q86B47	Drosophila melanogaster	29%	79%
Q873H9	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	25%	100%
Q8NHQ9	Homo sapiens	32%	100%
Q8TFL3	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	27%	100%
Q94C75	Arabidopsis thaliana	29%	100%
Q9C8S9	Arabidopsis thaliana	27%	97%
Q9FNM7	Arabidopsis thaliana	29%	91%
Q9H8H2	Homo sapiens	33%	91%
Q9NVP1	Homo sapiens	36%	100%
Q9UTP9	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	32%	100%
Q9VD51	Drosophila melanogaster	36%	100%
V5DCA1	Trypanosoma cruzi	57%	100%