Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q550_LEIMA

TriTrypDb:

LmjF.32.2250 , LMJLV39_320029400 , LMJSD75_320029500

Length:

347

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q550

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q550

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	170	174	PF00656	0.548
CLV_NRD_NRD_1	243	245	PF00675	0.431
CLV_NRD_NRD_1	332	334	PF00675	0.449
CLV_PCSK_KEX2_1	242	244	PF00082	0.494
CLV_PCSK_KEX2_1	277	279	PF00082	0.453
CLV_PCSK_KEX2_1	319	321	PF00082	0.521
CLV_PCSK_PC1ET2_1	277	279	PF00082	0.453
CLV_PCSK_PC1ET2_1	319	321	PF00082	0.368
CLV_PCSK_PC7_1	238	244	PF00082	0.472
CLV_PCSK_SKI1_1	110	114	PF00082	0.365
CLV_PCSK_SKI1_1	319	323	PF00082	0.500
DEG_SCF_FBW7_1	59	66	PF00400	0.511
DEG_SPOP_SBC_1	194	198	PF00917	0.586
DOC_CYCLIN_RxL_1	313	324	PF00134	0.402
DOC_MAPK_gen_1	242	251	PF00069	0.556
DOC_MAPK_MEF2A_6	242	250	PF00069	0.409
DOC_PP1_RVXF_1	108	114	PF00149	0.284
DOC_WW_Pin1_4	171	176	PF00397	0.599
DOC_WW_Pin1_4	293	298	PF00397	0.620
DOC_WW_Pin1_4	43	48	PF00397	0.651
DOC_WW_Pin1_4	59	64	PF00397	0.559
LIG_14-3-3_CanoR_1	149	157	PF00244	0.409
LIG_14-3-3_CanoR_1	216	224	PF00244	0.617
LIG_BRCT_BRCA1_1	232	236	PF00533	0.478
LIG_FHA_1	10	16	PF00498	0.794
LIG_FHA_1	135	141	PF00498	0.376
LIG_FHA_1	179	185	PF00498	0.720
LIG_FHA_1	200	206	PF00498	0.677
LIG_FHA_1	227	233	PF00498	0.538
LIG_FHA_1	261	267	PF00498	0.404
LIG_FHA_1	28	34	PF00498	0.531
LIG_FHA_1	326	332	PF00498	0.462
LIG_FHA_2	115	121	PF00498	0.367
LIG_FHA_2	196	202	PF00498	0.660
LIG_FHA_2	210	216	PF00498	0.654
LIG_PTAP_UEV_1	288	293	PF05743	0.570
LIG_SH2_GRB2like	129	132	PF00017	0.438
LIG_SH2_STAP1	142	146	PF00017	0.458
LIG_SH2_STAT5	114	117	PF00017	0.332
LIG_SH2_STAT5	129	132	PF00017	0.397
LIG_SH2_STAT5	180	183	PF00017	0.677
LIG_SH3_3	169	175	PF00018	0.618
LIG_SH3_3	286	292	PF00018	0.566
LIG_SH3_3	299	305	PF00018	0.507
LIG_SUMO_SIM_anti_2	122	129	PF11976	0.415
LIG_TRAF2_1	279	282	PF00917	0.515
LIG_UBA3_1	248	254	PF00899	0.407
LIG_WW_3	305	309	PF00397	0.478
MOD_CK1_1	10	16	PF00069	0.583
MOD_CK1_1	179	185	PF00069	0.593
MOD_CK1_1	196	202	PF00069	0.658
MOD_CK1_1	226	232	PF00069	0.697
MOD_CK1_1	3	9	PF00069	0.659
MOD_CK1_1	31	37	PF00069	0.666
MOD_CK1_1	40	46	PF00069	0.574
MOD_CK1_1	57	63	PF00069	0.530
MOD_CK2_1	114	120	PF00069	0.441
MOD_CK2_1	26	32	PF00069	0.658
MOD_CK2_1	276	282	PF00069	0.514
MOD_GlcNHglycan	168	172	PF01048	0.625
MOD_GlcNHglycan	181	184	PF01048	0.512
MOD_GlcNHglycan	2	5	PF01048	0.583
MOD_GlcNHglycan	42	45	PF01048	0.640
MOD_GlcNHglycan	94	97	PF01048	0.527
MOD_GSK3_1	149	156	PF00069	0.452
MOD_GSK3_1	167	174	PF00069	0.504
MOD_GSK3_1	179	186	PF00069	0.771
MOD_GSK3_1	189	196	PF00069	0.654
MOD_GSK3_1	226	233	PF00069	0.638
MOD_GSK3_1	27	34	PF00069	0.597
MOD_GSK3_1	292	299	PF00069	0.557
MOD_GSK3_1	3	10	PF00069	0.615
MOD_GSK3_1	36	43	PF00069	0.638
MOD_GSK3_1	55	62	PF00069	0.470
MOD_GSK3_1	73	80	PF00069	0.583
MOD_GSK3_1	92	99	PF00069	0.294
MOD_N-GLC_1	230	235	PF02516	0.520
MOD_N-GLC_1	40	45	PF02516	0.656
MOD_N-GLC_1	7	12	PF02516	0.734
MOD_NEK2_1	112	117	PF00069	0.398
MOD_NEK2_1	325	330	PF00069	0.390
MOD_NEK2_2	77	82	PF00069	0.523
MOD_PKA_2	148	154	PF00069	0.379
MOD_PKA_2	215	221	PF00069	0.593
MOD_Plk_1	167	173	PF00069	0.559
MOD_Plk_1	209	215	PF00069	0.583
MOD_Plk_1	40	46	PF00069	0.793
MOD_Plk_1	96	102	PF00069	0.353
MOD_Plk_2-3	209	215	PF00069	0.673
MOD_Plk_2-3	276	282	PF00069	0.514
MOD_Plk_4	296	302	PF00069	0.535
MOD_Plk_4	325	331	PF00069	0.386
MOD_ProDKin_1	171	177	PF00069	0.600
MOD_ProDKin_1	293	299	PF00069	0.620
MOD_ProDKin_1	43	49	PF00069	0.650
MOD_ProDKin_1	59	65	PF00069	0.556
TRG_DiLeu_BaEn_4	275	281	PF01217	0.379
TRG_DiLeu_BaLyEn_6	86	91	PF01217	0.461
TRG_ER_diArg_1	242	244	PF00400	0.444
TRG_Pf-PMV_PEXEL_1	278	282	PF00026	0.474

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I1Y8	Leptomonas seymouri	46%	99%
A0A3S7X5S5	Leishmania donovani	93%	100%
A4HKL6	Leishmania braziliensis	64%	100%
A4I848	Leishmania infantum	93%	100%
E9B306	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%