EamA domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q542_LEIMA

TriTrypDb:

LmjF.32.2330 , LMJLV39_320030200 , LMJSD75_320030300

Length:

139


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	10
GO:0110165	cellular anatomical entity	1	10

Q4Q542

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q542


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_SKI1_1	59	63	PF00082	0.260
DEG_APCC_DBOX_1	74	82	PF00400	0.470
DEG_COP1_1	25	32	PF00400	0.387
DEG_Nend_Nbox_1	1	3	PF02207	0.330
DOC_MAPK_MEF2A_6	34	42	PF00069	0.336
DOC_PP1_RVXF_1	57	64	PF00149	0.253
DOC_USP7_MATH_1	135	139	PF00917	0.651
DOC_USP7_MATH_1	23	27	PF00917	0.404
DOC_WW_Pin1_4	111	116	PF00397	0.401
DOC_WW_Pin1_4	83	88	PF00397	0.479
LIG_Actin_WH2_2	43	61	PF00022	0.298
LIG_Clathr_ClatBox_1	106	110	PF01394	0.362
LIG_EH1_1	62	70	PF00400	0.252
LIG_FHA_1	94	100	PF00498	0.366
LIG_LIR_Nem_3	72	77	PF02991	0.575
LIG_PDZ_Class_2	134	139	PF00595	0.643
LIG_SH2_STAT5	39	42	PF00017	0.446
LIG_SH2_STAT5	77	80	PF00017	0.481
LIG_SH3_3	129	135	PF00018	0.463
MOD_GlcNHglycan	100	103	PF01048	0.287
MOD_GlcNHglycan	15	18	PF01048	0.461
MOD_GlcNHglycan	34	37	PF01048	0.599
MOD_GSK3_1	24	31	PF00069	0.314
MOD_GSK3_1	79	86	PF00069	0.479
MOD_N-GLC_1	4	9	PF02516	0.564
MOD_NEK2_1	32	37	PF00069	0.324
MOD_NEK2_1	69	74	PF00069	0.460
MOD_NEK2_1	98	103	PF00069	0.267
MOD_PIKK_1	79	85	PF00454	0.578
MOD_Plk_1	24	30	PF00069	0.294
MOD_Plk_1	4	10	PF00069	0.361
MOD_Plk_2-3	43	49	PF00069	0.331
MOD_Plk_4	28	34	PF00069	0.379
MOD_Plk_4	69	75	PF00069	0.482
MOD_ProDKin_1	111	117	PF00069	0.304
MOD_ProDKin_1	83	89	PF00069	0.475
TRG_ENDOCYTIC_2	39	42	PF00928	0.439
TRG_PTS2	1	42	PF00400	0.313


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1II38	Leptomonas seymouri	83%	73%
A0A0S4IRV5	Bodo saltans	46%	78%
A0A1X0NRG8	Trypanosomatidae	49%	73%
A0A1X0NUK8	Trypanosomatidae	48%	73%
A0A3Q8IH44	Leishmania donovani	99%	100%
A0A3R7KNK3	Trypanosoma rangeli	54%	78%
A4HKM4	Leishmania braziliensis	91%	100%
A4I856	Leishmania infantum	98%	100%
D0AAC3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	45%	87%