Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q536_LEIMA

TriTrypDb:

LmjF.32.2390 , LMJLV39_320030800 , LMJSD75_320030900

Length:

523

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 8
NetGPI	no	yes: 0, no: 8

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q536

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q536

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	294	298	PF00656	0.753
CLV_C14_Caspase3-7	519	523	PF00656	0.654
CLV_NRD_NRD_1	123	125	PF00675	0.722
CLV_NRD_NRD_1	139	141	PF00675	0.608
CLV_NRD_NRD_1	143	145	PF00675	0.542
CLV_NRD_NRD_1	147	149	PF00675	0.623
CLV_NRD_NRD_1	226	228	PF00675	0.687
CLV_NRD_NRD_1	318	320	PF00675	0.609
CLV_NRD_NRD_1	455	457	PF00675	0.579
CLV_NRD_NRD_1	67	69	PF00675	0.627

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P596	Leptomonas seymouri	41%	96%
A0A1X0NRH9	Trypanosomatidae	24%	100%
A0A3Q8IL99	Leishmania donovani	89%	100%
A4HKN0	Leishmania braziliensis	71%	99%
A4I857	Leishmania infantum	89%	100%
D0AAC7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	26%	100%
E9B318	Leishmania mexicana (strain MHOM/GT/2001/U1103)	86%	100%

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