LeishMANIAdb
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CHCH domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
CHCH domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania major
UniProt:
Q4Q516_LEIMA
TriTrypDb:
LmjF.32.2590 , LMJLV39_320033200 * , LMJSD75_320033500
Length:
132

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 8
NetGPI no yes: 0, no: 8
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q516
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q516

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 69 71 PF00675 0.613
CLV_PCSK_KEX2_1 69 71 PF00082 0.574
CLV_PCSK_SKI1_1 62 66 PF00082 0.699
DOC_CKS1_1 72 77 PF01111 0.574
DOC_USP7_MATH_1 22 26 PF00917 0.717
DOC_USP7_MATH_2 27 33 PF00917 0.555
DOC_USP7_UBL2_3 62 66 PF12436 0.693
DOC_WW_Pin1_4 7 12 PF00397 0.721
DOC_WW_Pin1_4 71 76 PF00397 0.567
LIG_14-3-3_CanoR_1 48 56 PF00244 0.636
LIG_14-3-3_CanoR_1 69 73 PF00244 0.646
LIG_BRCT_BRCA1_1 111 115 PF00533 0.518
LIG_FHA_2 3 9 PF00498 0.686
LIG_LIR_Apic_2 71 75 PF02991 0.567
LIG_LIR_Nem_3 29 33 PF02991 0.787
LIG_LIR_Nem_3 63 68 PF02991 0.692
LIG_PDZ_Class_2 127 132 PF00595 0.531
LIG_Pex14_1 72 76 PF04695 0.570
LIG_SH3_3 21 27 PF00018 0.664
LIG_TRAF2_1 5 8 PF00917 0.615
MOD_CK1_1 71 77 PF00069 0.604
MOD_CK2_1 2 8 PF00069 0.686
MOD_GlcNHglycan 11 14 PF01048 0.719
MOD_GlcNHglycan 59 62 PF01048 0.654
MOD_N-GLC_1 2 7 PF02516 0.791
MOD_NEK2_1 115 120 PF00069 0.412
MOD_PIKK_1 22 28 PF00454 0.551
MOD_PIKK_1 88 94 PF00454 0.595
MOD_PKA_2 68 74 PF00069 0.645
MOD_ProDKin_1 7 13 PF00069 0.721
MOD_ProDKin_1 71 77 PF00069 0.570
TRG_ER_diArg_1 68 70 PF00400 0.649

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PF38 Leptomonas seymouri 53% 100%
A0A1X0NRK0 Trypanosomatidae 54% 100%
A0A3Q8IH69 Leishmania donovani 89% 100%
A0A422NHY0 Trypanosoma rangeli 53% 100%
A4HKP9 Leishmania braziliensis 76% 100%
A4I880 Leishmania infantum 89% 100%
E9B338 Leishmania mexicana (strain MHOM/GT/2001/U1103) 86% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS