Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

mucin-like protein, putative

Species:

Leishmania major

UniProt:

Q4Q4Z8_LEIMA

TriTrypDb:

LmjF.32.2770 , LMJLV39_320035200 , LMJSD75_320035400

Length:

960

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q4Z8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q4Z8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	243	247	PF00656	0.792
CLV_C14_Caspase3-7	825	829	PF00656	0.665
CLV_NRD_NRD_1	152	154	PF00675	0.765
CLV_NRD_NRD_1	172	174	PF00675	0.327
CLV_NRD_NRD_1	195	197	PF00675	0.504
CLV_NRD_NRD_1	267	269	PF00675	0.743
CLV_NRD_NRD_1	417	419	PF00675	0.780
CLV_NRD_NRD_1	448	450	PF00675	0.717
CLV_NRD_NRD_1	520	522	PF00675	0.755
CLV_NRD_NRD_1	627	629	PF00675	0.780
CLV_NRD_NRD_1	665	667	PF00675	0.752
CLV_NRD_NRD_1	905	907	PF00675	0.648
CLV_NRD_NRD_1	946	948	PF00675	0.753
CLV_PCSK_FUR_1	173	177	PF00082	0.673
CLV_PCSK_FUR_1	193	197	PF00082	0.388
CLV_PCSK_KEX2_1	152	154	PF00082	0.624
CLV_PCSK_KEX2_1	172	174	PF00082	0.327
CLV_PCSK_KEX2_1	175	177	PF00082	0.682
CLV_PCSK_KEX2_1	195	197	PF00082	0.393
CLV_PCSK_KEX2_1	267	269	PF00082	0.743
CLV_PCSK_KEX2_1	419	421	PF00082	0.845
CLV_PCSK_KEX2_1	448	450	PF00082	0.717
CLV_PCSK_KEX2_1	665	667	PF00082	0.742
CLV_PCSK_KEX2_1	670	672	PF00082	0.690
CLV_PCSK_KEX2_1	905	907	PF00082	0.648
CLV_PCSK_PC1ET2_1	175	177	PF00082	0.681
CLV_PCSK_PC1ET2_1	419	421	PF00082	0.845
CLV_PCSK_PC1ET2_1	670	672	PF00082	0.710
CLV_PCSK_PC7_1	666	672	PF00082	0.723
CLV_PCSK_SKI1_1	172	176	PF00082	0.584
CLV_PCSK_SKI1_1	260	264	PF00082	0.723
CLV_PCSK_SKI1_1	335	339	PF00082	0.852
CLV_PCSK_SKI1_1	356	360	PF00082	0.780
CLV_PCSK_SKI1_1	510	514	PF00082	0.618
CLV_PCSK_SKI1_1	628	632	PF00082	0.786
CLV_PCSK_SKI1_1	642	646	PF00082	0.754
CLV_PCSK_SKI1_1	671	675	PF00082	0.741
CLV_PCSK_SKI1_1	875	879	PF00082	0.803
CLV_Separin_Metazoa	169	173	PF03568	0.563
DEG_APCC_DBOX_1	674	682	PF00400	0.664
DEG_COP1_1	202	211	PF00400	0.740
DEG_Nend_UBRbox_1	1	4	PF02207	0.722
DEG_SCF_FBW7_1	708	715	PF00400	0.597
DEG_SPOP_SBC_1	33	37	PF00917	0.632
DEG_SPOP_SBC_1	430	434	PF00917	0.745
DEG_SPOP_SBC_1	611	615	PF00917	0.759
DEG_SPOP_SBC_1	648	652	PF00917	0.806
DEG_SPOP_SBC_1	829	833	PF00917	0.715
DOC_CDC14_PxL_1	57	65	PF14671	0.725
DOC_CKS1_1	227	232	PF01111	0.841
DOC_CKS1_1	342	347	PF01111	0.734
DOC_CKS1_1	889	894	PF01111	0.637
DOC_CYCLIN_RxL_1	353	362	PF00134	0.779
DOC_CYCLIN_RxL_1	507	516	PF00134	0.623
DOC_CYCLIN_yCln2_LP_2	477	483	PF00134	0.651
DOC_MAPK_DCC_7	675	683	PF00069	0.666
DOC_MAPK_FxFP_2	322	325	PF00069	0.830
DOC_PP2B_LxvP_1	30	33	PF13499	0.815
DOC_PP2B_LxvP_1	477	480	PF13499	0.601
DOC_PP2B_PxIxI_1	766	772	PF00149	0.765
DOC_PP4_FxxP_1	227	230	PF00568	0.839
DOC_PP4_FxxP_1	322	325	PF00568	0.668
DOC_PP4_FxxP_1	342	345	PF00568	0.743
DOC_PP4_FxxP_1	942	945	PF00568	0.766
DOC_USP7_MATH_1	16	20	PF00917	0.814
DOC_USP7_MATH_1	201	205	PF00917	0.801
DOC_USP7_MATH_1	294	298	PF00917	0.822
DOC_USP7_MATH_1	325	329	PF00917	0.833
DOC_USP7_MATH_1	34	38	PF00917	0.552
DOC_USP7_MATH_1	39	43	PF00917	0.789
DOC_USP7_MATH_1	430	434	PF00917	0.652
DOC_USP7_MATH_1	462	466	PF00917	0.834
DOC_USP7_MATH_1	561	565	PF00917	0.677
DOC_USP7_MATH_1	598	602	PF00917	0.732
DOC_USP7_MATH_1	606	610	PF00917	0.776
DOC_USP7_MATH_1	611	615	PF00917	0.669
DOC_USP7_MATH_1	727	731	PF00917	0.809
DOC_USP7_MATH_1	757	761	PF00917	0.813
DOC_USP7_MATH_1	777	781	PF00917	0.782
DOC_USP7_MATH_1	791	795	PF00917	0.588
DOC_USP7_MATH_1	817	821	PF00917	0.716
DOC_USP7_MATH_1	829	833	PF00917	0.619
DOC_USP7_MATH_1	861	865	PF00917	0.800
DOC_USP7_MATH_1	900	904	PF00917	0.733
DOC_USP7_MATH_1	913	917	PF00917	0.648
DOC_USP7_UBL2_3	522	526	PF12436	0.767
DOC_WW_Pin1_4	10	15	PF00397	0.790
DOC_WW_Pin1_4	133	138	PF00397	0.772
DOC_WW_Pin1_4	207	212	PF00397	0.768
DOC_WW_Pin1_4	221	226	PF00397	0.685
DOC_WW_Pin1_4	245	250	PF00397	0.739
DOC_WW_Pin1_4	341	346	PF00397	0.740
DOC_WW_Pin1_4	406	411	PF00397	0.786
DOC_WW_Pin1_4	426	431	PF00397	0.517
DOC_WW_Pin1_4	458	463	PF00397	0.660
DOC_WW_Pin1_4	541	546	PF00397	0.688
DOC_WW_Pin1_4	588	593	PF00397	0.691
DOC_WW_Pin1_4	635	640	PF00397	0.613
DOC_WW_Pin1_4	649	654	PF00397	0.542
DOC_WW_Pin1_4	708	713	PF00397	0.652
DOC_WW_Pin1_4	720	725	PF00397	0.698
DOC_WW_Pin1_4	775	780	PF00397	0.827
DOC_WW_Pin1_4	800	805	PF00397	0.733
DOC_WW_Pin1_4	888	893	PF00397	0.703
LIG_14-3-3_CanoR_1	284	289	PF00244	0.714
LIG_14-3-3_CanoR_1	335	345	PF00244	0.853
LIG_14-3-3_CanoR_1	420	428	PF00244	0.779
LIG_14-3-3_CanoR_1	562	566	PF00244	0.767
LIG_14-3-3_CanoR_1	582	592	PF00244	0.853
LIG_14-3-3_CanoR_1	597	606	PF00244	0.569
LIG_14-3-3_CanoR_1	628	637	PF00244	0.657
LIG_14-3-3_CanoR_1	707	712	PF00244	0.710
LIG_14-3-3_CanoR_1	786	793	PF00244	0.809
LIG_14-3-3_CanoR_1	816	823	PF00244	0.834
LIG_14-3-3_CanoR_1	836	840	PF00244	0.536
LIG_14-3-3_CanoR_1	865	871	PF00244	0.646
LIG_Actin_WH2_2	613	630	PF00022	0.630
LIG_BIR_III_4	876	880	PF00653	0.750
LIG_BRCT_BRCA1_1	126	130	PF00533	0.788
LIG_BRCT_BRCA1_1	223	227	PF00533	0.842
LIG_BRCT_BRCA1_1	338	342	PF00533	0.854
LIG_CSL_BTD_1	28	31	PF09270	0.813
LIG_deltaCOP1_diTrp_1	159	168	PF00928	0.696
LIG_EVH1_1	30	34	PF00568	0.814
LIG_FHA_1	283	289	PF00498	0.751
LIG_FHA_1	293	299	PF00498	0.691
LIG_FHA_1	471	477	PF00498	0.619
LIG_FHA_1	570	576	PF00498	0.758
LIG_FHA_1	622	628	PF00498	0.669
LIG_FHA_1	643	649	PF00498	0.827
LIG_FHA_1	69	75	PF00498	0.741
LIG_FHA_1	713	719	PF00498	0.828
LIG_FHA_1	736	742	PF00498	0.758
LIG_FHA_1	832	838	PF00498	0.789
LIG_FHA_1	850	856	PF00498	0.558
LIG_FHA_2	394	400	PF00498	0.786
LIG_FHA_2	656	662	PF00498	0.705
LIG_FHA_2	672	678	PF00498	0.590
LIG_GBD_Chelix_1	359	367	PF00786	0.825
LIG_LIR_Apic_2	224	230	PF02991	0.720
LIG_LIR_Apic_2	339	345	PF02991	0.742
LIG_LIR_Apic_2	73	78	PF02991	0.737
LIG_LIR_Apic_2	940	945	PF02991	0.624
LIG_LIR_Gen_1	127	137	PF02991	0.780
LIG_LIR_Gen_1	166	174	PF02991	0.652
LIG_LIR_Nem_3	127	133	PF02991	0.784
LIG_LIR_Nem_3	164	170	PF02991	0.511
LIG_LIR_Nem_3	454	458	PF02991	0.724
LIG_LRP6_Inhibitor_1	104	110	PF00058	0.677
LIG_MYND_1	484	488	PF01753	0.765
LIG_MYND_3	483	487	PF01753	0.766
LIG_PDZ_Class_2	955	960	PF00595	0.727
LIG_Pex14_1	163	167	PF04695	0.681
LIG_SH2_CRK	75	79	PF00017	0.736
LIG_SH2_SRC	251	254	PF00017	0.702
LIG_SH2_SRC	62	65	PF00017	0.575
LIG_SH2_STAT3	351	354	PF00017	0.732
LIG_SH2_STAT5	132	135	PF00017	0.780
LIG_SH2_STAT5	251	254	PF00017	0.738
LIG_SH2_STAT5	62	65	PF00017	0.722
LIG_SH3_1	508	514	PF00018	0.734
LIG_SH3_1	679	685	PF00018	0.737
LIG_SH3_2	889	894	PF14604	0.637
LIG_SH3_3	203	209	PF00018	0.813
LIG_SH3_3	25	31	PF00018	0.626
LIG_SH3_3	342	348	PF00018	0.623
LIG_SH3_3	491	497	PF00018	0.761
LIG_SH3_3	508	514	PF00018	0.560
LIG_SH3_3	544	550	PF00018	0.681
LIG_SH3_3	562	568	PF00018	0.686
LIG_SH3_3	650	656	PF00018	0.700
LIG_SH3_3	679	685	PF00018	0.763
LIG_SH3_3	71	77	PF00018	0.739
LIG_SH3_3	721	727	PF00018	0.736
LIG_SH3_3	751	757	PF00018	0.785
LIG_SH3_3	760	766	PF00018	0.691
LIG_SH3_3	8	14	PF00018	0.727
LIG_SH3_3	836	842	PF00018	0.857
LIG_SH3_3	848	854	PF00018	0.660
LIG_SH3_3	886	892	PF00018	0.726
LIG_SH3_3	894	900	PF00018	0.748
LIG_SH3_4	522	529	PF00018	0.765
LIG_SUMO_SIM_anti_2	473	480	PF11976	0.604
LIG_SUMO_SIM_par_1	553	558	PF11976	0.830
LIG_TRAF2_1	113	116	PF00917	0.569
LIG_TRAF2_1	178	181	PF00917	0.657
MOD_CAAXbox	957	960	PF01239	0.795
MOD_CDK_SPK_2	207	212	PF00069	0.746
MOD_CDK_SPK_2	458	463	PF00069	0.700
MOD_CDK_SPxK_1	888	894	PF00069	0.639
MOD_CDK_SPxxK_3	226	233	PF00069	0.841
MOD_CDK_SPxxK_3	635	642	PF00069	0.614
MOD_CK1_1	19	25	PF00069	0.689
MOD_CK1_1	202	208	PF00069	0.812
MOD_CK1_1	221	227	PF00069	0.523
MOD_CK1_1	287	293	PF00069	0.790
MOD_CK1_1	309	315	PF00069	0.852
MOD_CK1_1	328	334	PF00069	0.523
MOD_CK1_1	336	342	PF00069	0.603
MOD_CK1_1	35	41	PF00069	0.587
MOD_CK1_1	352	358	PF00069	0.561
MOD_CK1_1	429	435	PF00069	0.824
MOD_CK1_1	454	460	PF00069	0.791
MOD_CK1_1	461	467	PF00069	0.704
MOD_CK1_1	47	53	PF00069	0.753
MOD_CK1_1	471	477	PF00069	0.549
MOD_CK1_1	569	575	PF00069	0.714
MOD_CK1_1	591	597	PF00069	0.834
MOD_CK1_1	600	606	PF00069	0.659
MOD_CK1_1	619	625	PF00069	0.569
MOD_CK1_1	729	735	PF00069	0.841
MOD_CK1_1	778	784	PF00069	0.798
MOD_CK1_1	831	837	PF00069	0.854
MOD_CK1_1	84	90	PF00069	0.588
MOD_CK1_1	849	855	PF00069	0.570
MOD_CK1_1	890	896	PF00069	0.803
MOD_CK1_1	916	922	PF00069	0.829
MOD_CK1_1	937	943	PF00069	0.709
MOD_CK2_1	110	116	PF00069	0.616
MOD_CK2_1	393	399	PF00069	0.796
MOD_CK2_1	500	506	PF00069	0.789
MOD_CK2_1	62	68	PF00069	0.723
MOD_CK2_1	655	661	PF00069	0.623
MOD_CK2_1	890	896	PF00069	0.718
MOD_Cter_Amidation	668	671	PF01082	0.762
MOD_GlcNHglycan	18	21	PF01048	0.784
MOD_GlcNHglycan	292	295	PF01048	0.778
MOD_GlcNHglycan	316	319	PF01048	0.721
MOD_GlcNHglycan	335	338	PF01048	0.853
MOD_GlcNHglycan	369	372	PF01048	0.728
MOD_GlcNHglycan	37	40	PF01048	0.510
MOD_GlcNHglycan	381	384	PF01048	0.854
MOD_GlcNHglycan	41	44	PF01048	0.679
MOD_GlcNHglycan	46	49	PF01048	0.614
MOD_GlcNHglycan	470	473	PF01048	0.729
MOD_GlcNHglycan	487	491	PF01048	0.591
MOD_GlcNHglycan	502	505	PF01048	0.593
MOD_GlcNHglycan	557	560	PF01048	0.702
MOD_GlcNHglycan	568	571	PF01048	0.677
MOD_GlcNHglycan	600	603	PF01048	0.726
MOD_GlcNHglycan	606	609	PF01048	0.647
MOD_GlcNHglycan	631	634	PF01048	0.686
MOD_GlcNHglycan	686	689	PF01048	0.765
MOD_GlcNHglycan	699	702	PF01048	0.618
MOD_GlcNHglycan	743	746	PF01048	0.776
MOD_GlcNHglycan	759	762	PF01048	0.609
MOD_GlcNHglycan	848	851	PF01048	0.785
MOD_GlcNHglycan	936	939	PF01048	0.724
MOD_GSK3_1	12	19	PF00069	0.765
MOD_GSK3_1	214	221	PF00069	0.722
MOD_GSK3_1	229	236	PF00069	0.602
MOD_GSK3_1	290	297	PF00069	0.805
MOD_GSK3_1	308	315	PF00069	0.851
MOD_GSK3_1	324	331	PF00069	0.570
MOD_GSK3_1	35	42	PF00069	0.811
MOD_GSK3_1	373	380	PF00069	0.826
MOD_GSK3_1	393	400	PF00069	0.833
MOD_GSK3_1	406	413	PF00069	0.631
MOD_GSK3_1	426	433	PF00069	0.537
MOD_GSK3_1	437	444	PF00069	0.669
MOD_GSK3_1	447	454	PF00069	0.698
MOD_GSK3_1	458	465	PF00069	0.631
MOD_GSK3_1	566	573	PF00069	0.734
MOD_GSK3_1	584	591	PF00069	0.688
MOD_GSK3_1	597	604	PF00069	0.751
MOD_GSK3_1	606	613	PF00069	0.653
MOD_GSK3_1	644	651	PF00069	0.752
MOD_GSK3_1	708	715	PF00069	0.774
MOD_GSK3_1	716	723	PF00069	0.752
MOD_GSK3_1	726	733	PF00069	0.581
MOD_GSK3_1	767	774	PF00069	0.829
MOD_GSK3_1	775	782	PF00069	0.690
MOD_GSK3_1	787	794	PF00069	0.545
MOD_GSK3_1	796	803	PF00069	0.685
MOD_GSK3_1	827	834	PF00069	0.812
MOD_GSK3_1	842	849	PF00069	0.597
MOD_GSK3_1	861	868	PF00069	0.590
MOD_GSK3_1	913	920	PF00069	0.785
MOD_LATS_1	231	237	PF00433	0.842
MOD_N-GLC_1	202	207	PF02516	0.812
MOD_N-GLC_1	271	276	PF02516	0.634
MOD_N-GLC_1	598	603	PF02516	0.702
MOD_N-GLC_1	866	871	PF02516	0.793
MOD_N-GLC_2	441	443	PF02516	0.768
MOD_NEK2_1	199	204	PF00069	0.746
MOD_NEK2_1	282	287	PF00069	0.635
MOD_NEK2_1	365	370	PF00069	0.696
MOD_NEK2_1	436	441	PF00069	0.740
MOD_NEK2_1	447	452	PF00069	0.660
MOD_NEK2_1	555	560	PF00069	0.695
MOD_NEK2_1	583	588	PF00069	0.791
MOD_NEK2_1	706	711	PF00069	0.758
MOD_NEK2_1	731	736	PF00069	0.831
MOD_NEK2_2	70	75	PF00069	0.744
MOD_PIKK_1	287	293	PF00454	0.790
MOD_PIKK_1	309	315	PF00454	0.778
MOD_PIKK_1	612	618	PF00454	0.759
MOD_PK_1	306	312	PF00069	0.850
MOD_PKA_1	419	425	PF00069	0.776
MOD_PKA_2	109	115	PF00069	0.595
MOD_PKA_2	397	403	PF00069	0.718
MOD_PKA_2	419	425	PF00069	0.776
MOD_PKA_2	441	447	PF00069	0.813
MOD_PKA_2	462	468	PF00069	0.737
MOD_PKA_2	561	567	PF00069	0.852
MOD_PKA_2	583	589	PF00069	0.865
MOD_PKA_2	604	610	PF00069	0.686
MOD_PKA_2	706	712	PF00069	0.753
MOD_PKA_2	785	791	PF00069	0.812
MOD_PKA_2	835	841	PF00069	0.787
MOD_PKA_2	913	919	PF00069	0.692
MOD_PKB_1	304	312	PF00069	0.849
MOD_PKB_1	418	426	PF00069	0.779
MOD_PKB_1	582	590	PF00069	0.791
MOD_Plk_1	138	144	PF00069	0.757
MOD_Plk_1	202	208	PF00069	0.812
MOD_Plk_1	570	576	PF00069	0.641
MOD_Plk_1	866	872	PF00069	0.646
MOD_Plk_4	284	290	PF00069	0.786
MOD_Plk_4	294	300	PF00069	0.663
MOD_Plk_4	462	468	PF00069	0.800
MOD_Plk_4	62	68	PF00069	0.656
MOD_Plk_4	70	76	PF00069	0.744
MOD_Plk_4	736	742	PF00069	0.814
MOD_ProDKin_1	10	16	PF00069	0.788
MOD_ProDKin_1	133	139	PF00069	0.771
MOD_ProDKin_1	207	213	PF00069	0.771
MOD_ProDKin_1	221	227	PF00069	0.687
MOD_ProDKin_1	245	251	PF00069	0.740
MOD_ProDKin_1	341	347	PF00069	0.734
MOD_ProDKin_1	406	412	PF00069	0.786
MOD_ProDKin_1	426	432	PF00069	0.514
MOD_ProDKin_1	458	464	PF00069	0.659
MOD_ProDKin_1	541	547	PF00069	0.683
MOD_ProDKin_1	588	594	PF00069	0.690
MOD_ProDKin_1	635	641	PF00069	0.613
MOD_ProDKin_1	649	655	PF00069	0.543
MOD_ProDKin_1	708	714	PF00069	0.653
MOD_ProDKin_1	720	726	PF00069	0.693
MOD_ProDKin_1	775	781	PF00069	0.828
MOD_ProDKin_1	800	806	PF00069	0.727
MOD_ProDKin_1	888	894	PF00069	0.705
MOD_SUMO_for_1	390	393	PF00179	0.651
MOD_SUMO_for_1	877	880	PF00179	0.825
MOD_SUMO_rev_2	181	190	PF00179	0.700
TRG_DiLeu_BaEn_4	180	186	PF01217	0.667
TRG_DiLeu_BaLyEn_6	508	513	PF01217	0.740
TRG_ENDOCYTIC_2	132	135	PF00928	0.780
TRG_ENDOCYTIC_2	167	170	PF00928	0.576
TRG_ENDOCYTIC_2	98	101	PF00928	0.726
TRG_ER_diArg_1	152	154	PF00400	0.765
TRG_ER_diArg_1	171	173	PF00400	0.333
TRG_ER_diArg_1	266	268	PF00400	0.743
TRG_ER_diArg_1	299	302	PF00400	0.846
TRG_ER_diArg_1	418	421	PF00400	0.774
TRG_ER_diArg_1	447	449	PF00400	0.718
TRG_ER_diArg_1	664	666	PF00400	0.721

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S7X5W9	Leishmania donovani	88%	100%
A4HKR8	Leishmania braziliensis	60%	100%
A4I898	Leishmania infantum	88%	100%
E9B356	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	100%