Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q4W1_LEIMA

TriTrypDb:

LmjF.32.3100 , LMJLV39_320039000 , LMJSD75_320039200

Length:

254

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q4W1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q4W1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	117	119	PF00675	0.513
CLV_NRD_NRD_1	40	42	PF00675	0.518
CLV_PCSK_KEX2_1	117	119	PF00082	0.513
CLV_PCSK_SKI1_1	118	122	PF00082	0.594
CLV_PCSK_SKI1_1	138	142	PF00082	0.443
CLV_PCSK_SKI1_1	57	61	PF00082	0.561
DEG_APCC_DBOX_1	117	125	PF00400	0.506
DEG_APCC_DBOX_1	223	231	PF00400	0.364
DEG_SPOP_SBC_1	79	83	PF00917	0.603
DOC_MAPK_MEF2A_6	224	231	PF00069	0.363
DOC_MAPK_NFAT4_5	224	232	PF00069	0.365
DOC_PP1_RVXF_1	55	62	PF00149	0.427
DOC_USP7_MATH_1	140	144	PF00917	0.601
DOC_USP7_MATH_1	155	159	PF00917	0.666
DOC_USP7_MATH_1	189	193	PF00917	0.677
DOC_USP7_MATH_1	2	6	PF00917	0.573
DOC_USP7_MATH_1	79	83	PF00917	0.738
DOC_WW_Pin1_4	88	93	PF00397	0.679
LIG_14-3-3_CanoR_1	182	190	PF00244	0.617
LIG_14-3-3_CanoR_1	34	39	PF00244	0.433
LIG_FHA_1	109	115	PF00498	0.387
LIG_FHA_1	14	20	PF00498	0.438
LIG_FHA_1	163	169	PF00498	0.706
LIG_FHA_2	6	12	PF00498	0.607
LIG_FHA_2	89	95	PF00498	0.610
LIG_GBD_Chelix_1	17	25	PF00786	0.435
LIG_LIR_Gen_1	223	231	PF02991	0.420
LIG_LIR_Nem_3	223	229	PF02991	0.459
LIG_NRBOX	226	232	PF00104	0.480
LIG_SH2_CRK	35	39	PF00017	0.430
LIG_SH2_STAT5	226	229	PF00017	0.481
LIG_SUMO_SIM_anti_2	225	231	PF11976	0.420
LIG_TRAF2_1	106	109	PF00917	0.488
LIG_TRAF2_1	70	73	PF00917	0.544
MOD_CK1_1	143	149	PF00069	0.581
MOD_CK1_1	163	169	PF00069	0.625
MOD_CK1_1	188	194	PF00069	0.689
MOD_CK1_1	5	11	PF00069	0.569
MOD_CK1_1	80	86	PF00069	0.708
MOD_CK2_1	5	11	PF00069	0.639
MOD_CK2_1	67	73	PF00069	0.670
MOD_CK2_1	81	87	PF00069	0.501
MOD_GlcNHglycan	157	160	PF01048	0.636
MOD_GlcNHglycan	187	190	PF01048	0.738
MOD_GlcNHglycan	191	194	PF01048	0.726
MOD_GlcNHglycan	196	199	PF01048	0.624
MOD_GlcNHglycan	69	72	PF01048	0.620
MOD_GSK3_1	108	115	PF00069	0.588
MOD_GSK3_1	185	192	PF00069	0.605
MOD_GSK3_1	33	40	PF00069	0.517
MOD_GSK3_1	77	84	PF00069	0.597
MOD_LATS_1	123	129	PF00433	0.488
MOD_NEK2_1	78	83	PF00069	0.749
MOD_PIKK_1	153	159	PF00454	0.636
MOD_PKA_2	33	39	PF00069	0.518
MOD_PKB_1	32	40	PF00069	0.518
MOD_PKB_1	63	71	PF00069	0.533
MOD_Plk_1	163	169	PF00069	0.558
MOD_Plk_1	57	63	PF00069	0.597
MOD_ProDKin_1	88	94	PF00069	0.677
TRG_DiLeu_BaEn_1	116	121	PF01217	0.446
TRG_DiLeu_BaEn_1	223	228	PF01217	0.476
TRG_ENDOCYTIC_2	226	229	PF00928	0.451
TRG_ENDOCYTIC_2	35	38	PF00928	0.417
TRG_ER_diArg_1	244	247	PF00400	0.670
TRG_ER_diArg_1	32	35	PF00400	0.527
TRG_Pf-PMV_PEXEL_1	118	122	PF00026	0.505
TRG_Pf-PMV_PEXEL_1	219	223	PF00026	0.549

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I8D0	Leptomonas seymouri	31%	70%
A0A3Q8IG66	Leishmania donovani	84%	83%
A4I8D5	Leishmania infantum	85%	83%
E9B394	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	91%