Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q4U8_LEIMA

TriTrypDb:

LmjF.32.3240 , LMJLV39_320040600 , LMJSD75_320040600

Length:

1190

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q4U8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q4U8

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	534	538	PF00656	0.557
CLV_C14_Caspase3-7	696	700	PF00656	0.533
CLV_NRD_NRD_1	1066	1068	PF00675	0.589
CLV_NRD_NRD_1	1130	1132	PF00675	0.670
CLV_NRD_NRD_1	146	148	PF00675	0.565
CLV_NRD_NRD_1	190	192	PF00675	0.595
CLV_NRD_NRD_1	224	226	PF00675	0.645
CLV_NRD_NRD_1	244	246	PF00675	0.642
CLV_NRD_NRD_1	485	487	PF00675	0.684
CLV_NRD_NRD_1	554	556	PF00675	0.590

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Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P3U8	Leptomonas seymouri	33%	100%
A0A3Q8IFR5	Leishmania donovani	89%	99%
A4HKW9	Leishmania braziliensis	68%	100%
A4I8E9	Leishmania infantum	89%	99%
E9B3A7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	99%

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