Dihydrolipoyl dehydrogenase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

dihydrolipoamide dehydrogenase, putative

Species:

Leishmania major

UniProt:

Q4Q4U1_LEIMA

TriTrypDb:

LmjF.32.3310 , LMJLV39_320041300 , LMJSD75_320041300

Length:

476

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 2
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 20

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	yes	yes: 6

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 12

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0005739	mitochondrion	5	2
GO:0032991	protein-containing complex	1	2
GO:0043226	organelle	2	2
GO:0043227	membrane-bounded organelle	3	2
GO:0043229	intracellular organelle	3	2
GO:0043231	intracellular membrane-bounded organelle	4	2
GO:0045239	tricarboxylic acid cycle enzyme complex	3	2
GO:0045240	dihydrolipoyl dehydrogenase complex	4	2
GO:0045252	oxoglutarate dehydrogenase complex	4	2
GO:0110165	cellular anatomical entity	1	2
GO:1902494	catalytic complex	2	2
GO:1990204	oxidoreductase complex	3	2
GO:1990234	transferase complex	3	2

Expansion

Sequence features

Q4Q4U1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q4U1

Function

Biological processes
Term	Name	Level	Count
GO:0009987	cellular process	1	12
GO:0019725	cellular homeostasis	2	12
GO:0042592	homeostatic process	3	12
GO:0045454	cell redox homeostasis	3	12
GO:0050789	regulation of biological process	2	12
GO:0050794	regulation of cellular process	3	12
GO:0065007	biological regulation	1	12
GO:0065008	regulation of biological quality	2	12

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003824	catalytic activity	1	12
GO:0004148	dihydrolipoyl dehydrogenase activity	5	12
GO:0005488	binding	1	12
GO:0016491	oxidoreductase activity	2	12
GO:0016667	oxidoreductase activity, acting on a sulfur group of donors	3	12
GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0050660	flavin adenine dinucleotide binding	4	12
GO:0097159	organic cyclic compound binding	2	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	263	267	PF00656	0.379
CLV_NRD_NRD_1	283	285	PF00675	0.337
CLV_NRD_NRD_1	3	5	PF00675	0.598
CLV_PCSK_KEX2_1	283	285	PF00082	0.337
CLV_PCSK_KEX2_1	3	5	PF00082	0.563
CLV_PCSK_KEX2_1	379	381	PF00082	0.347
CLV_PCSK_KEX2_1	42	44	PF00082	0.320
CLV_PCSK_PC1ET2_1	379	381	PF00082	0.347
CLV_PCSK_PC1ET2_1	42	44	PF00082	0.320
CLV_PCSK_SKI1_1	228	232	PF00082	0.411
CLV_PCSK_SKI1_1	241	245	PF00082	0.313
CLV_PCSK_SKI1_1	408	412	PF00082	0.379
CLV_PCSK_SKI1_1	43	47	PF00082	0.352
CLV_PCSK_SKI1_1	59	63	PF00082	0.260
CLV_PCSK_SKI1_1	99	103	PF00082	0.335
DEG_Nend_Nbox_1	1	3	PF02207	0.559
DEG_SPOP_SBC_1	170	174	PF00917	0.320
DOC_CYCLIN_RxL_1	56	65	PF00134	0.320
DOC_MAPK_gen_1	413	423	PF00069	0.382
DOC_MAPK_MEF2A_6	414	423	PF00069	0.379
DOC_MAPK_RevD_3	132	148	PF00069	0.354
DOC_PP4_FxxP_1	126	129	PF00568	0.377
DOC_USP7_MATH_1	152	156	PF00917	0.320
DOC_USP7_MATH_1	224	228	PF00917	0.463
DOC_USP7_MATH_1	456	460	PF00917	0.335
LIG_14-3-3_CanoR_1	217	226	PF00244	0.390
LIG_Actin_WH2_2	21	38	PF00022	0.354
LIG_APCC_ABBA_1	162	167	PF00400	0.320
LIG_FHA_1	103	109	PF00498	0.224
LIG_FHA_1	129	135	PF00498	0.391
LIG_FHA_1	172	178	PF00498	0.324
LIG_FHA_1	229	235	PF00498	0.346
LIG_FHA_1	244	250	PF00498	0.320
LIG_FHA_1	257	263	PF00498	0.320
LIG_FHA_1	285	291	PF00498	0.320
LIG_FHA_1	35	41	PF00498	0.353
LIG_FHA_1	413	419	PF00498	0.320
LIG_FHA_1	85	91	PF00498	0.371
LIG_FHA_2	151	157	PF00498	0.320
LIG_FHA_2	208	214	PF00498	0.320
LIG_FHA_2	220	226	PF00498	0.320
LIG_FHA_2	361	367	PF00498	0.320
LIG_FHA_2	455	461	PF00498	0.320
LIG_LIR_Apic_2	123	129	PF02991	0.377
LIG_LIR_Gen_1	200	209	PF02991	0.357
LIG_LIR_Gen_1	300	310	PF02991	0.335
LIG_LIR_Gen_1	403	410	PF02991	0.320
LIG_LIR_Nem_3	159	165	PF02991	0.463
LIG_LIR_Nem_3	200	205	PF02991	0.336
LIG_LIR_Nem_3	300	306	PF02991	0.335
LIG_LIR_Nem_3	403	409	PF02991	0.320
LIG_LRP6_Inhibitor_1	127	133	PF00058	0.395
LIG_PDZ_Class_2	471	476	PF00595	0.414
LIG_SH2_CRK	354	358	PF00017	0.394
LIG_SH2_GRB2like	362	365	PF00017	0.463
LIG_SH2_NCK_1	354	358	PF00017	0.397
LIG_SH2_NCK_1	362	366	PF00017	0.315
LIG_SH2_SRC	318	321	PF00017	0.335
LIG_SH2_STAP1	12	16	PF00017	0.335
LIG_SH2_STAT5	110	113	PF00017	0.335
LIG_SH2_STAT5	24	27	PF00017	0.317
LIG_SH2_STAT5	362	365	PF00017	0.320
LIG_SH3_3	158	164	PF00018	0.320
LIG_SUMO_SIM_anti_2	13	18	PF11976	0.356
LIG_SUMO_SIM_anti_2	208	213	PF11976	0.338
LIG_SUMO_SIM_par_1	256	264	PF11976	0.355
LIG_TRAF2_1	334	337	PF00917	0.463
LIG_TYR_ITIM	352	357	PF00017	0.392
MOD_CK1_1	146	152	PF00069	0.359
MOD_CK1_1	155	161	PF00069	0.281
MOD_CK1_1	256	262	PF00069	0.505
MOD_CK1_1	392	398	PF00069	0.413
MOD_CK2_1	150	156	PF00069	0.320
MOD_CK2_1	207	213	PF00069	0.320
MOD_CK2_1	360	366	PF00069	0.320
MOD_CK2_1	454	460	PF00069	0.320
MOD_Cter_Amidation	281	284	PF01082	0.337
MOD_GlcNHglycan	249	252	PF01048	0.341
MOD_GlcNHglycan	391	394	PF01048	0.413
MOD_GlcNHglycan	89	93	PF01048	0.462
MOD_GSK3_1	146	153	PF00069	0.320
MOD_GSK3_1	224	231	PF00069	0.463
MOD_GSK3_1	243	250	PF00069	0.299
MOD_GSK3_1	408	415	PF00069	0.379
MOD_GSK3_1	8	15	PF00069	0.569
MOD_GSK3_1	84	91	PF00069	0.433
MOD_N-GLC_1	253	258	PF02516	0.475
MOD_N-GLC_1	352	357	PF02516	0.347
MOD_N-GLC_1	84	89	PF02516	0.496
MOD_NEK2_1	171	176	PF00069	0.324
MOD_NEK2_1	243	248	PF00069	0.333
MOD_NEK2_1	277	282	PF00069	0.335
MOD_NEK2_1	448	453	PF00069	0.323
MOD_NEK2_1	46	51	PF00069	0.345
MOD_NEK2_1	470	475	PF00069	0.425
MOD_NEK2_1	62	67	PF00069	0.372
MOD_NEK2_1	88	93	PF00069	0.433
MOD_Plk_1	12	18	PF00069	0.463
MOD_Plk_1	140	146	PF00069	0.443
MOD_Plk_1	207	213	PF00069	0.354
MOD_Plk_1	352	358	PF00069	0.346
MOD_Plk_1	84	90	PF00069	0.371
MOD_Plk_2-3	84	90	PF00069	0.354
MOD_Plk_4	115	121	PF00069	0.349
MOD_Plk_4	12	18	PF00069	0.463
MOD_Plk_4	122	128	PF00069	0.372
MOD_Plk_4	146	152	PF00069	0.320
MOD_Plk_4	197	203	PF00069	0.344
MOD_Plk_4	207	213	PF00069	0.320
MOD_Plk_4	352	358	PF00069	0.487
MOD_SUMO_for_1	235	238	PF00179	0.331
MOD_SUMO_rev_2	141	149	PF00179	0.339
TRG_DiLeu_BaEn_1	273	278	PF01217	0.463
TRG_ENDOCYTIC_2	354	357	PF00928	0.396
TRG_ER_diArg_1	2	4	PF00400	0.567
TRG_ER_diArg_1	283	285	PF00400	0.329
TRG_NLS_MonoExtC_3	377	383	PF00514	0.395
TRG_Pf-PMV_PEXEL_1	417	422	PF00026	0.463

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P491	Leptomonas seymouri	90%	100%
A0A0N1HUA4	Leptomonas seymouri	27%	84%
A0A0N1I1H2	Leptomonas seymouri	29%	97%
A0A0N1IHT7	Leptomonas seymouri	29%	94%
A0A0N1IIN8	Leptomonas seymouri	26%	91%
A0A0S4J6A3	Bodo saltans	30%	96%
A0A0S4JDA8	Bodo saltans	72%	100%
A0A0S4KLJ6	Bodo saltans	27%	76%
A0A1X0NJ18	Trypanosomatidae	25%	74%
A0A1X0NK15	Trypanosomatidae	28%	81%
A0A1X0NRW2	Trypanosomatidae	78%	100%
A0A1X0NZX1	Trypanosomatidae	27%	94%
A0A1X0P0G9	Trypanosomatidae	29%	97%
A0A3Q8IDT8	Leishmania donovani	30%	94%
A0A3Q8IF30	Leishmania donovani	27%	87%
A0A3Q8ITM5	Leishmania donovani	99%	100%
A0A3R7KY91	Trypanosoma rangeli	75%	100%
A0A3R7NB58	Trypanosoma rangeli	28%	97%
A0A3R7NSH5	Trypanosoma rangeli	27%	94%
A0A3S7WP12	Leishmania donovani	27%	97%
A0A3S7X4X4	Leishmania donovani	25%	76%
A0A422NPA5	Trypanosoma rangeli	25%	77%
A0A422NPB5	Trypanosoma rangeli	28%	81%
A1AIE2	Escherichia coli O1:K1 / APEC	30%	100%
A1JI37	Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081)	31%	100%
A1KM51	Mycobacterium bovis (strain BCG / Pasteur 1173P2)	35%	100%
A1U1Y5	Marinobacter nauticus (strain ATCC 700491 / DSM 11845 / VT8)	31%	100%
A2TIL1	Callithrix jacchus	26%	91%
A4H480	Leishmania braziliensis	29%	97%
A4HIY7	Leishmania braziliensis	30%	94%
A4HJQ2	Leishmania braziliensis	27%	92%
A4HKX6	Leishmania braziliensis	92%	100%
A4HSF7	Leishmania infantum	27%	97%
A4I4P1	Leishmania infantum	30%	94%
A4I769	Leishmania infantum	25%	100%
A4I8F6	Leishmania infantum	99%	100%
A4TRG4	Yersinia pestis (strain Pestoides F)	31%	100%
A4VMU6	Pseudomonas stutzeri (strain A1501)	30%	100%
A4WG49	Enterobacter sp. (strain 638)	31%	100%
A4X398	Salinispora tropica (strain ATCC BAA-916 / DSM 44818 / CNB-440)	23%	100%
A4XSQ1	Pseudomonas mendocina (strain ymp)	30%	100%
A4YER6	Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2)	24%	100%
A5F4K5	Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)	31%	100%
A5U665	Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)	35%	100%
A5W6F5	Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1)	32%	100%
A6TGE6	Klebsiella pneumoniae subsp. pneumoniae (strain ATCC 700721 / MGH 78578)	30%	100%
A6V3A6	Pseudomonas aeruginosa (strain PA7)	29%	100%
A6VW16	Marinomonas sp. (strain MWYL1)	32%	100%
A7FD10	Yersinia pseudotuberculosis serotype O:1b (strain IP 31758)	31%	100%
A7ZUI2	Escherichia coli O139:H28 (strain E24377A / ETEC)	30%	100%
A8A770	Escherichia coli O9:H4 (strain HS)	30%	100%
A8AKW0	Citrobacter koseri (strain ATCC BAA-895 / CDC 4225-83 / SGSC4696)	30%	100%
A8GL77	Serratia proteamaculans (strain 568)	30%	100%
A8M2W8	Salinispora arenicola (strain CNS-205)	25%	100%
A8MS68	Arabidopsis thaliana	35%	76%
A9N0H2	Salmonella paratyphi B (strain ATCC BAA-1250 / SPB7)	30%	100%
A9R6N5	Yersinia pestis bv. Antiqua (strain Angola)	31%	100%
B0KH90	Pseudomonas putida (strain GB-1)	32%	100%
B1IVB6	Escherichia coli (strain ATCC 8739 / DSM 1576 / NBRC 3972 / NCIMB 8545 / WDCM 00012 / Crooks)	30%	100%
B1J606	Pseudomonas putida (strain W619)	32%	100%
B1JQ50	Yersinia pseudotuberculosis serotype O:3 (strain YPIII)	31%	100%
B1LNS2	Escherichia coli (strain SMS-3-5 / SECEC)	30%	100%
B1MX70	Leuconostoc citreum (strain KM20)	21%	100%
B1XBX3	Escherichia coli (strain K12 / DH10B)	30%	100%
B2JZF3	Yersinia pseudotuberculosis serotype IB (strain PB1/+)	31%	100%
B2TWF7	Shigella boydii serotype 18 (strain CDC 3083-94 / BS512)	30%	100%
B2VGA0	Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99)	31%	100%
B3EKW5	Chlorobium phaeobacteroides (strain BS1)	25%	100%
B3QXE1	Chloroherpeton thalassium (strain ATCC 35110 / GB-78)	24%	100%
B4F1H1	Proteus mirabilis (strain HI4320)	31%	100%
B4S9F8	Prosthecochloris aestuarii (strain DSM 271 / SK 413)	25%	100%
B4U394	Streptococcus equi subsp. zooepidemicus (strain MGCS10565)	23%	100%
B5BJN6	Salmonella paratyphi A (strain AKU_12601)	30%	100%
B5QXQ7	Salmonella enteritidis PT4 (strain P125109)	30%	100%
B5REZ6	Salmonella gallinarum (strain 287/91 / NCTC 13346)	30%	100%
B5XZ14	Klebsiella pneumoniae (strain 342)	30%	100%
B5Z064	Escherichia coli O157:H7 (strain EC4115 / EHEC)	30%	100%
B6I5I0	Escherichia coli (strain SE11)	30%	100%
B7LA64	Escherichia coli (strain 55989 / EAEC)	30%	100%
B7LUN3	Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73)	30%	100%
B7M718	Escherichia coli O8 (strain IAI1)	30%	100%
B7MIA0	Escherichia coli O45:K1 (strain S88 / ExPEC)	30%	100%
B7MR55	Escherichia coli O81 (strain ED1a)	30%	100%
B7NFR2	Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC)	30%	100%
B7NU38	Escherichia coli O7:K1 (strain IAI39 / ExPEC)	30%	100%
B7UNU0	Escherichia coli O127:H6 (strain E2348/69 / EPEC)	30%	100%
B7UZU5	Pseudomonas aeruginosa (strain LESB58)	30%	100%
B7VM91	Vibrio atlanticus (strain LGP32)	31%	100%
B9A1H3	Emiliania huxleyi	26%	96%
C0Q478	Salmonella paratyphi C (strain RKS4594)	30%	100%
C1AFH2	Mycobacterium bovis (strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019)	35%	100%
C1DR10	Azotobacter vinelandii (strain DJ / ATCC BAA-1303)	31%	100%
C3K4W1	Pseudomonas fluorescens (strain SBW25)	31%	100%
C3LPZ2	Vibrio cholerae serotype O1 (strain M66-2)	31%	100%
C4K3I8	Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT)	29%	100%
C5A0R1	Escherichia coli (strain K12 / MC4100 / BW2952)	30%	100%
C9ZLC8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	94%
C9ZMF4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	79%
C9ZWN2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	27%	87%
D0A4H8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	28%	97%
D0AAR5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	77%	100%
D0VWY5	Marichromatium gracile	29%	100%
E9AE44	Leishmania major	30%	94%
E9AHL8	Leishmania infantum	27%	87%
E9AKE1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	27%	97%
E9ALP1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	30%	94%
E9B263	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	74%
E9B264	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	87%
E9B3B4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	97%	100%
F4JLP5	Arabidopsis thaliana	34%	84%
G0SB20	Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719)	53%	94%
O00087	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	55%	93%
O04955	Brassica rapa subsp. pekinensis	28%	95%
O05139	Pseudomonas fluorescens	31%	100%
O05204	Staphylococcus aureus (strain NCTC 8325 / PS 47)	29%	94%
O05940	Rhizobium etli (strain CFN 42 / ATCC 51251)	40%	99%
O08749	Mus musculus	51%	94%
O15770	Plasmodium falciparum (isolate 3D7)	28%	87%
O17953	Caenorhabditis elegans	55%	96%
O18480	Manduca sexta	53%	96%
O32823	Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)	25%	100%
O34324	Bacillus subtilis (strain 168)	34%	100%
O50286	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	42%	100%
O50311	Chlorobaculum parvum (strain DSM 263 / NCIMB 8327)	39%	100%
O62768	Bos taurus	28%	95%
O84561	Chlamydia trachomatis (strain D/UW-3/Cx)	39%	100%
O89049	Rattus norvegicus	28%	95%
P00390	Homo sapiens	28%	91%
P00392	Pseudomonas aeruginosa	31%	85%
P06715	Escherichia coli (strain K12)	31%	100%
P08332	Shigella flexneri	30%	84%
P09063	Pseudomonas putida	40%	100%
P09622	Homo sapiens	53%	94%
P09623	Sus scrofa	53%	94%
P09624	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	55%	95%
P0A0E4	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	34%	87%
P0A0E5	Staphylococcus aureus	34%	87%
P0A0E6	Staphylococcus aureus (strain Mu50 / ATCC 700699)	44%	100%
P0A0E7	Staphylococcus aureus (strain MW2)	44%	100%
P0A0E8	Staphylococcus aureus	44%	100%
P0A9P0	Escherichia coli (strain K12)	41%	100%
P0A9P1	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	41%	100%
P0A9P2	Escherichia coli O157:H7	41%	100%
P0A9P3	Shigella flexneri	41%	100%
P11959	Geobacillus stearothermophilus	45%	100%
P13110	Trypanosoma congolense	28%	97%
P14218	Pseudomonas fluorescens	49%	100%
P16171	Bacillus cereus	36%	75%
P17239	Acidithiobacillus ferrooxidans	28%	87%
P18925	Azotobacter vinelandii	49%	100%
P21880	Bacillus subtilis (strain 168)	44%	100%
P23189	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	31%	100%
P27306	Escherichia coli (strain K12)	30%	100%
P27456	Pisum sativum	28%	86%
P28593	Trypanosoma cruzi	27%	97%
P30341	Streptomyces lividans	30%	100%
P30635	Caenorhabditis elegans	27%	95%
P31023	Pisum sativum	58%	95%
P31046	Pseudomonas putida	51%	100%
P31052	Pseudomonas putida	49%	100%
P35484	Acholeplasma laidlawii	39%	100%
P37062	Enterococcus faecalis (strain ATCC 700802 / V583)	26%	100%
P39040	Crithidia fasciculata	28%	97%
P39050	Leishmania donovani	26%	97%
P39051	Trypanosoma brucei brucei	28%	97%
P41921	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	30%	99%
P42770	Arabidopsis thaliana	27%	84%
P43783	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	29%	100%
P43784	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	41%	100%
P47513	Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)	37%	100%
P47791	Mus musculus	28%	95%
P48638	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	28%	100%
P48639	Burkholderia cepacia	27%	100%
P48640	Glycine max	27%	88%
P48641	Arabidopsis thaliana	28%	95%
P48642	Oryza sativa subsp. japonica	27%	96%
P49819	Canis lupus familiaris	52%	94%
P50529	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	31%	100%
P50970	Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)	38%	100%
P52992	Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337)	49%	100%
P54533	Bacillus subtilis (strain 168)	41%	100%
P57112	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	30%	100%
P57303	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	35%	100%
P61076	Plasmodium falciparum (isolate 3D7)	28%	77%
P66005	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	40%	100%
P66007	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	35%	100%
P66008	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	30%	100%
P66009	Salmonella typhi	30%	100%
P66012	Staphylococcus aureus (strain Mu50 / ATCC 700699)	28%	94%
P66013	Staphylococcus aureus (strain MW2)	28%	94%
P70619	Rattus norvegicus	25%	100%
P72740	Synechocystis sp. (strain PCC 6803 / Kazusa)	35%	100%
P75393	Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)	38%	100%
P77212	Escherichia coli (strain K12)	29%	100%
P78965	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	29%	100%
P80461	Nicotiana tabacum	27%	85%
P85207	Thermus scotoductus (strain ATCC 700910 / SA-01)	46%	100%
P90597	Trypanosoma cruzi	77%	100%
P91938	Drosophila melanogaster	28%	80%
P94188	Alcaligenes sp.	30%	85%
P94284	Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31)	27%	100%
P94702	Enterobacter agglomerans	29%	85%
P95596	Rhodobacter capsulatus	54%	100%
P99084	Staphylococcus aureus (strain N315)	44%	100%
P99118	Staphylococcus aureus (strain N315)	28%	94%
P9WHH0	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	25%	100%
P9WHH1	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	25%	100%
P9WHH2	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	26%	100%
P9WHH3	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	26%	100%
P9WHH4	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	35%	100%
P9WHH5	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	35%	100%
P9WHH6	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	25%	97%
P9WHH7	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	25%	97%
P9WHH8	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	40%	100%
P9WHH9	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	40%	100%
Q02733	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	33%	95%
Q02PF5	Pseudomonas aeruginosa (strain UCBPP-PA14)	30%	100%
Q04829	Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2)	41%	100%
Q04933	Trypanosoma brucei brucei	75%	99%
Q0TA96	Escherichia coli O6:K15:H31 (strain 536 / UPEC)	30%	100%
Q16881	Homo sapiens	27%	73%
Q17745	Caenorhabditis elegans	25%	71%
Q1CBU5	Yersinia pestis bv. Antiqua (strain Antiqua)	31%	100%
Q1CNP4	Yersinia pestis bv. Antiqua (strain Nepal516)	31%	100%
Q1I7F0	Pseudomonas entomophila (strain L48)	32%	100%
Q1QX78	Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11)	30%	100%
Q1R3U7	Escherichia coli (strain UTI89 / UPEC)	30%	100%
Q25861	Plasmodium falciparum (isolate FCH-5)	28%	88%
Q2NQZ3	Sodalis glossinidius (strain morsitans)	30%	100%
Q2SIP2	Hahella chejuensis (strain KCTC 2396)	32%	100%
Q3K9F5	Pseudomonas fluorescens (strain Pf0-1)	31%	100%
Q41219	Glycine max	57%	91%
Q43154	Spinacia oleracea	29%	97%
Q43621	Pisum sativum	27%	96%
Q48A14	Colwellia psychrerythraea (strain 34H / ATCC BAA-681)	31%	100%
Q48KI8	Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6)	30%	100%
Q4KFA6	Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5)	31%	100%
Q4Q5Z6	Leishmania major	25%	85%
Q4Q5Z7	Leishmania major	25%	77%
Q4QJG7	Leishmania major	28%	97%
Q4ZV77	Pseudomonas syringae pv. syringae (strain B728a)	31%	100%
Q50068	Mycobacterium leprae (strain TN)	39%	100%
Q51772	Pseudomonas fluorescens	31%	87%
Q52109	Acinetobacter calcoaceticus	31%	85%
Q54465	Shewanella putrefaciens	33%	85%
Q54EW8	Dictyostelium discoideum	54%	98%
Q56839	Xanthobacter autotrophicus (strain ATCC BAA-1158 / Py2)	23%	91%
Q57H91	Salmonella choleraesuis (strain SC-B67)	30%	100%
Q58065	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	26%	100%
Q5E212	Aliivibrio fischeri (strain ATCC 700601 / ES114)	33%	100%
Q5HGY8	Staphylococcus aureus (strain COL)	44%	100%
Q5HIR6	Staphylococcus aureus (strain COL)	29%	94%
Q5HRY2	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	25%	94%
Q5JGP4	Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)	26%	100%
Q5NVA2	Pongo abelii	27%	95%
Q5PK71	Salmonella paratyphi A (strain ATCC 9150 / SARB42)	30%	100%
Q5R4B1	Pongo abelii	52%	94%
Q5UWH2	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	38%	100%
Q5UYG6	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	42%	100%
Q5XC60	Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)	27%	100%
Q60151	Streptococcus thermophilus	29%	100%
Q60HG3	Macaca fascicularis	52%	94%
Q66G61	Yersinia pseudotuberculosis serotype I (strain IP32953)	31%	100%
Q6BPI1	Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968)	26%	97%
Q6C5H4	Yarrowia lipolytica (strain CLIB 122 / E 150)	31%	100%
Q6CZB1	Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)	32%	100%
Q6FRV2	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	29%	100%
Q6GAB8	Staphylococcus aureus (strain MSSA476)	44%	100%
Q6GC92	Staphylococcus aureus (strain MSSA476)	28%	94%
Q6GHY9	Staphylococcus aureus (strain MRSA252)	44%	100%
Q6GJR8	Staphylococcus aureus (strain MRSA252)	28%	94%
Q6HA23	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	29%	98%
Q6LLT9	Photobacterium profundum (strain SS9)	32%	100%
Q6P6R2	Rattus norvegicus	52%	94%
Q74ZK4	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	28%	99%
Q7MBG9	Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)	31%	100%
Q7MQ83	Vibrio vulnificus (strain YJ016)	31%	100%
Q811C4	Mesocricetus auratus	52%	99%
Q83MI1	Shigella flexneri	31%	100%
Q86VQ6	Homo sapiens	27%	74%
Q873E8	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	28%	100%
Q87KN5	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	30%	100%
Q884I6	Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)	30%	100%
Q88KY8	Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)	32%	100%
Q89AQ8	Buchnera aphidicola subsp. Baizongia pistaciae (strain Bp)	36%	100%
Q8CIZ7	Cricetulus griseus	52%	94%
Q8CMQ1	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	25%	94%
Q8DD46	Vibrio vulnificus (strain CMCP6)	31%	100%
Q8DUN5	Streptococcus mutans serotype c (strain ATCC 700610 / UA159)	25%	100%
Q8EWR4	Malacoplasma penetrans (strain HF-2)	23%	100%
Q8FB93	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	30%	100%
Q8K9T7	Buchnera aphidicola subsp. Schizaphis graminum (strain Sg)	37%	100%
Q8KCW2	Chlorobaculum tepidum (strain ATCC 49652 / DSM 12025 / NBRC 103806 / TLS)	41%	100%
Q8NTE1	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)	40%	100%
Q8T137	Dictyostelium discoideum	28%	100%
Q8U1M0	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)	24%	100%
Q8X727	Escherichia coli O157:H7	30%	100%
Q8ZA97	Yersinia pestis	31%	100%
Q928B5	Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)	25%	100%
Q93379	Caenorhabditis elegans	27%	100%
Q94655	Plasmodium falciparum (isolate K1 / Thailand)	28%	95%
Q99MD6	Mus musculus	28%	73%
Q9HN74	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	41%	100%
Q9HUY1	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	48%	100%
Q9I1L9	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	38%	100%
Q9I3D1	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	49%	100%
Q9JLT4	Mus musculus	30%	91%
Q9JMH6	Mus musculus	28%	78%
Q9KPF6	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	42%	100%
Q9M5K2	Arabidopsis thaliana	59%	94%
Q9M5K3	Arabidopsis thaliana	59%	94%
Q9MYY8	Sus scrofa	27%	95%
Q9N2I8	Bos taurus	29%	93%
Q9NNW7	Homo sapiens	28%	91%
Q9PJI3	Chlamydia muridarum (strain MoPn / Nigg)	39%	100%
Q9SPB1	Vigna unguiculata	57%	91%
Q9UYU5	Pyrococcus abyssi (strain GE5 / Orsay)	25%	100%
Q9VNT5	Drosophila melanogaster	26%	92%
Q9XBQ9	Azotobacter vinelandii	31%	100%
Q9Z0J5	Rattus norvegicus	30%	90%
Q9Z773	Chlamydia pneumoniae	39%	100%
V5AJG2	Trypanosoma cruzi	27%	97%
V5B6P6	Trypanosoma cruzi	29%	86%
V5BB90	Trypanosoma cruzi	25%	87%
V5BDX2	Trypanosoma cruzi	28%	93%
V5BVJ1	Trypanosoma cruzi	77%	100%