Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q4R7_LEIMA

TriTrypDb:

LmjF.32.3550 , LMJLV39_320043500 , LMJSD75_320043500

Length:

444

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q4R7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q4R7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	176	180	PF00656	0.568
CLV_C14_Caspase3-7	379	383	PF00656	0.688
CLV_NRD_NRD_1	254	256	PF00675	0.661
CLV_NRD_NRD_1	257	259	PF00675	0.628
CLV_NRD_NRD_1	356	358	PF00675	0.702
CLV_NRD_NRD_1	369	371	PF00675	0.663
CLV_NRD_NRD_1	405	407	PF00675	0.697
CLV_PCSK_FUR_1	403	407	PF00082	0.578
CLV_PCSK_KEX2_1	254	256	PF00082	0.620
CLV_PCSK_KEX2_1	320	322	PF00082	0.651
CLV_PCSK_KEX2_1	355	357	PF00082	0.646
CLV_PCSK_KEX2_1	368	370	PF00082	0.559
CLV_PCSK_KEX2_1	403	405	PF00082	0.691
CLV_PCSK_KEX2_1	414	416	PF00082	0.613
CLV_PCSK_KEX2_1	73	75	PF00082	0.609
CLV_PCSK_PC1ET2_1	320	322	PF00082	0.651
CLV_PCSK_PC1ET2_1	414	416	PF00082	0.701
CLV_PCSK_PC1ET2_1	73	75	PF00082	0.700
CLV_PCSK_SKI1_1	172	176	PF00082	0.596
CLV_PCSK_SKI1_1	415	419	PF00082	0.676
DEG_MDM2_SWIB_1	220	228	PF02201	0.578
DEG_Nend_Nbox_1	1	3	PF02207	0.643
DOC_MAPK_MEF2A_6	165	173	PF00069	0.544
DOC_USP7_MATH_1	101	105	PF00917	0.606
DOC_USP7_MATH_1	123	127	PF00917	0.548
DOC_USP7_MATH_1	192	196	PF00917	0.717
DOC_USP7_MATH_1	233	237	PF00917	0.524
DOC_USP7_MATH_1	319	323	PF00917	0.733
DOC_USP7_MATH_1	349	353	PF00917	0.647
DOC_USP7_MATH_1	36	40	PF00917	0.527
DOC_USP7_MATH_1	408	412	PF00917	0.575
DOC_USP7_MATH_1	421	425	PF00917	0.524
DOC_USP7_MATH_1	69	73	PF00917	0.549
DOC_USP7_UBL2_3	410	414	PF12436	0.659
DOC_WW_Pin1_4	190	195	PF00397	0.749
DOC_WW_Pin1_4	342	347	PF00397	0.658
DOC_WW_Pin1_4	389	394	PF00397	0.665
DOC_WW_Pin1_4	92	97	PF00397	0.561
LIG_14-3-3_CanoR_1	122	132	PF00244	0.581
LIG_14-3-3_CanoR_1	270	274	PF00244	0.688
LIG_14-3-3_CanoR_1	275	284	PF00244	0.689
LIG_14-3-3_CanoR_1	439	444	PF00244	0.604
LIG_14-3-3_CanoR_1	68	75	PF00244	0.603
LIG_Actin_WH2_2	156	174	PF00022	0.587
LIG_Actin_WH2_2	215	231	PF00022	0.510
LIG_BIR_III_2	93	97	PF00653	0.542
LIG_Clathr_ClatBox_1	219	223	PF01394	0.502
LIG_DCNL_PONY_1	1	4	PF03556	0.567
LIG_deltaCOP1_diTrp_1	223	227	PF00928	0.439
LIG_FHA_1	155	161	PF00498	0.618
LIG_FHA_1	173	179	PF00498	0.479
LIG_FHA_1	248	254	PF00498	0.507
LIG_FHA_2	148	154	PF00498	0.577
LIG_FHA_2	88	94	PF00498	0.706
LIG_GBD_Chelix_1	206	214	PF00786	0.589
LIG_GBD_Chelix_1	53	61	PF00786	0.599
LIG_LIR_Gen_1	223	232	PF02991	0.644
LIG_LIR_Gen_1	5	14	PF02991	0.505
LIG_LIR_Nem_3	223	227	PF02991	0.631
LIG_LIR_Nem_3	5	10	PF02991	0.506
LIG_PCNA_PIPBox_1	1	10	PF02747	0.477
LIG_PDZ_Class_1	439	444	PF00595	0.602
LIG_Pex14_1	213	217	PF04695	0.579
LIG_Pex14_2	217	221	PF04695	0.563
LIG_SH2_STAP1	300	304	PF00017	0.564
LIG_SH2_STAT3	299	302	PF00017	0.620
LIG_SH2_STAT5	216	219	PF00017	0.577
LIG_SH2_STAT5	75	78	PF00017	0.582
LIG_SH3_3	138	144	PF00018	0.610
LIG_SH3_3	343	349	PF00018	0.653
LIG_SH3_3	79	85	PF00018	0.562
LIG_TRAF2_1	18	21	PF00917	0.601
LIG_UBA3_1	45	52	PF00899	0.499
LIG_WRC_WIRS_1	4	9	PF05994	0.470
MOD_CK1_1	195	201	PF00069	0.655
MOD_CK1_1	231	237	PF00069	0.559
MOD_CK1_1	3	9	PF00069	0.614
MOD_CK1_1	375	381	PF00069	0.694
MOD_CK1_1	39	45	PF00069	0.475
MOD_CK1_1	87	93	PF00069	0.647
MOD_CK2_1	15	21	PF00069	0.590
MOD_CK2_1	333	339	PF00069	0.633
MOD_Cter_Amidation	353	356	PF01082	0.563
MOD_GlcNHglycan	101	104	PF01048	0.622
MOD_GlcNHglycan	107	110	PF01048	0.703
MOD_GlcNHglycan	126	129	PF01048	0.477
MOD_GlcNHglycan	156	160	PF01048	0.635
MOD_GlcNHglycan	199	202	PF01048	0.500
MOD_GlcNHglycan	233	236	PF01048	0.587
MOD_GlcNHglycan	277	280	PF01048	0.613
MOD_GlcNHglycan	312	315	PF01048	0.615
MOD_GlcNHglycan	351	354	PF01048	0.669
MOD_GlcNHglycan	382	386	PF01048	0.657
MOD_GlcNHglycan	422	426	PF01048	0.589
MOD_GlcNHglycan	64	68	PF01048	0.635
MOD_GlcNHglycan	86	89	PF01048	0.694
MOD_GSK3_1	101	108	PF00069	0.637
MOD_GSK3_1	143	150	PF00069	0.693
MOD_GSK3_1	151	158	PF00069	0.633
MOD_GSK3_1	192	199	PF00069	0.549
MOD_GSK3_1	227	234	PF00069	0.609
MOD_GSK3_1	254	261	PF00069	0.735
MOD_GSK3_1	310	317	PF00069	0.604
MOD_GSK3_1	372	379	PF00069	0.689
MOD_GSK3_1	383	390	PF00069	0.545
MOD_GSK3_1	63	70	PF00069	0.584
MOD_GSK3_1	92	99	PF00069	0.679
MOD_N-GLC_1	376	381	PF02516	0.556
MOD_NEK2_1	173	178	PF00069	0.599
MOD_NEK2_1	196	201	PF00069	0.527
MOD_NEK2_1	206	211	PF00069	0.543
MOD_NEK2_1	227	232	PF00069	0.608
MOD_NEK2_1	330	335	PF00069	0.659
MOD_NEK2_1	63	68	PF00069	0.579
MOD_PIKK_1	101	107	PF00454	0.705
MOD_PIKK_1	331	337	PF00454	0.657
MOD_PIKK_1	36	42	PF00454	0.563
MOD_PKA_1	254	260	PF00069	0.605
MOD_PKA_1	320	326	PF00069	0.647
MOD_PKA_1	73	79	PF00069	0.774
MOD_PKA_2	105	111	PF00069	0.606
MOD_PKA_2	154	160	PF00069	0.497
MOD_PKA_2	228	234	PF00069	0.512
MOD_PKA_2	254	260	PF00069	0.624
MOD_PKA_2	269	275	PF00069	0.551
MOD_PKA_2	320	326	PF00069	0.647
MOD_PKA_2	67	73	PF00069	0.643
MOD_Plk_1	155	161	PF00069	0.608
MOD_Plk_1	376	382	PF00069	0.572
MOD_Plk_4	192	198	PF00069	0.651
MOD_Plk_4	3	9	PF00069	0.638
MOD_ProDKin_1	190	196	PF00069	0.749
MOD_ProDKin_1	342	348	PF00069	0.660
MOD_ProDKin_1	389	395	PF00069	0.668
MOD_ProDKin_1	92	98	PF00069	0.561
TRG_ENDOCYTIC_2	216	219	PF00928	0.606
TRG_ER_diArg_1	119	122	PF00400	0.633
TRG_ER_diArg_1	253	255	PF00400	0.561
TRG_ER_diArg_1	355	357	PF00400	0.636
TRG_ER_diArg_1	367	370	PF00400	0.609
TRG_ER_diArg_1	403	406	PF00400	0.651
TRG_ER_diArg_1	438	441	PF00400	0.639

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3S5H7T2	Leishmania donovani	83%	100%
A4HKZ5	Leishmania braziliensis	58%	99%
A4I8H5	Leishmania infantum	83%	100%
E9B3D5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	100%