Vacuolar ATPase assembly integral membrane protein VMA21 homolog

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q4R3_LEIMA

TriTrypDb:

LmjF.32.3590 , LMJLV39_320043900 , LMJSD75_320043900

Length:

117


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	9
GO:0110165	cellular anatomical entity	1	9

Q4Q4R3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q4R3


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	85	87	PF00675	0.405
CLV_PCSK_KEX2_1	84	86	PF00082	0.425
DOC_CYCLIN_yCln2_LP_2	60	66	PF00134	0.333
DOC_PP2B_LxvP_1	60	63	PF13499	0.307
DOC_USP7_MATH_1	72	76	PF00917	0.418
LIG_14-3-3_CanoR_1	85	95	PF00244	0.746
LIG_Actin_WH2_2	67	82	PF00022	0.425
LIG_BRCT_BRCA1_1	67	71	PF00533	0.425
LIG_FHA_1	20	26	PF00498	0.680
LIG_FHA_1	55	61	PF00498	0.283
LIG_IRF3_LxIS_1	44	49	PF10401	0.419
LIG_LIR_Gen_1	104	114	PF02991	0.567
LIG_LIR_Gen_1	27	37	PF02991	0.471
LIG_LIR_Gen_1	41	50	PF02991	0.311
LIG_LIR_Gen_1	68	79	PF02991	0.381
LIG_LIR_Nem_3	104	109	PF02991	0.617
LIG_LIR_Nem_3	27	32	PF02991	0.559
LIG_LIR_Nem_3	41	46	PF02991	0.311
LIG_LIR_Nem_3	68	74	PF02991	0.399
LIG_SH2_PTP2	43	46	PF00017	0.333
LIG_SH2_STAP1	96	100	PF00017	0.699
LIG_SH2_STAT5	43	46	PF00017	0.333
LIG_SH3_3	106	112	PF00018	0.714
LIG_SUMO_SIM_par_1	35	41	PF11976	0.354
MOD_CK1_1	5	11	PF00069	0.673
MOD_CK1_1	56	62	PF00069	0.249
MOD_GlcNHglycan	26	29	PF01048	0.376
MOD_GlcNHglycan	4	7	PF01048	0.465
MOD_GlcNHglycan	48	51	PF01048	0.564
MOD_GlcNHglycan	60	63	PF01048	0.365
MOD_GSK3_1	38	45	PF00069	0.434
MOD_GSK3_1	54	61	PF00069	0.368
MOD_NEK2_1	46	51	PF00069	0.544
MOD_PIKK_1	19	25	PF00454	0.652
MOD_PIKK_1	86	92	PF00454	0.710
MOD_PKB_1	84	92	PF00069	0.700
MOD_Plk_4	38	44	PF00069	0.474
MOD_Plk_4	74	80	PF00069	0.365
TRG_ENDOCYTIC_2	43	46	PF00928	0.333
TRG_ER_diArg_1	84	86	PF00400	0.613


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PBG0	Leptomonas seymouri	57%	96%
A0A1X0NRX6	Trypanosomatidae	38%	98%
A0A3R7LD90	Trypanosoma rangeli	32%	98%
A0A3S7X638	Leishmania donovani	89%	100%
A4I8H9	Leishmania infantum	88%	100%
E9AIV3	Leishmania braziliensis	73%	100%
E9B3D9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	100%
V5DMF6	Trypanosoma cruzi	34%	98%