Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q4Q9_LEIMA

TriTrypDb:

LmjF.32.3630 , LMJLV39_320044300 , LMJSD75_320044300

Length:

317

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q4Q9

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q4Q9

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	278	282	PF00656	0.544
CLV_C14_Caspase3-7	57	61	PF00656	0.669
CLV_PCSK_SKI1_1	201	205	PF00082	0.422
DEG_Nend_UBRbox_2	1	3	PF02207	0.657
DEG_SCF_FBW7_1	123	128	PF00400	0.639
DOC_CYCLIN_yCln2_LP_2	300	306	PF00134	0.713
DOC_MAPK_gen_1	214	222	PF00069	0.486
DOC_PP2B_LxvP_1	103	106	PF13499	0.826
DOC_PP2B_LxvP_1	300	303	PF13499	0.696
DOC_USP7_MATH_1	115	119	PF00917	0.660
DOC_USP7_MATH_1	130	134	PF00917	0.557
DOC_USP7_MATH_1	167	171	PF00917	0.717
DOC_USP7_MATH_1	254	258	PF00917	0.611
DOC_USP7_MATH_1	286	290	PF00917	0.680
DOC_USP7_MATH_1	304	308	PF00917	0.509
DOC_USP7_MATH_1	53	57	PF00917	0.670
DOC_USP7_MATH_1	61	65	PF00917	0.804
DOC_USP7_MATH_1	75	79	PF00917	0.811
DOC_USP7_MATH_1	8	12	PF00917	0.824
DOC_USP7_MATH_1	98	102	PF00917	0.690
DOC_USP7_MATH_2	89	95	PF00917	0.782
DOC_WW_Pin1_4	121	126	PF00397	0.822
DOC_WW_Pin1_4	13	18	PF00397	0.692
LIG_14-3-3_CanoR_1	214	222	PF00244	0.504
LIG_14-3-3_CanoR_1	228	237	PF00244	0.504
LIG_14-3-3_CanoR_1	27	37	PF00244	0.581
LIG_14-3-3_CanoR_1	276	280	PF00244	0.629
LIG_14-3-3_CanoR_1	55	59	PF00244	0.617
LIG_Actin_WH2_2	251	267	PF00022	0.530
LIG_CaM_IQ_9	235	250	PF13499	0.526
LIG_CSL_BTD_1	207	210	PF09270	0.549
LIG_EH1_1	137	145	PF00400	0.586
LIG_FHA_1	126	132	PF00498	0.628
LIG_FHA_1	202	208	PF00498	0.429
LIG_FHA_1	215	221	PF00498	0.315
LIG_FHA_2	156	162	PF00498	0.759
LIG_FHA_2	285	291	PF00498	0.657
LIG_GBD_Chelix_1	292	300	PF00786	0.671
LIG_LIR_Nem_3	205	211	PF02991	0.544
LIG_LIR_Nem_3	38	43	PF02991	0.603
LIG_Pex14_1	208	212	PF04695	0.536
LIG_SH2_CRK	212	216	PF00017	0.501
LIG_SH2_GRB2like	221	224	PF00017	0.542
LIG_SH2_PTP2	36	39	PF00017	0.620
LIG_SH2_SRC	36	39	PF00017	0.663
LIG_SH2_SRC	58	61	PF00017	0.577
LIG_SH2_STAP1	43	47	PF00017	0.712
LIG_SH2_STAT3	236	239	PF00017	0.513
LIG_SH2_STAT5	221	224	PF00017	0.607
LIG_SH2_STAT5	236	239	PF00017	0.367
LIG_SH2_STAT5	36	39	PF00017	0.638
LIG_SH2_STAT5	47	50	PF00017	0.558
LIG_SH2_STAT5	58	61	PF00017	0.723
LIG_SH3_3	204	210	PF00018	0.647
LIG_TRAF2_1	89	92	PF00917	0.791
MOD_CK1_1	101	107	PF00069	0.660
MOD_CK1_1	11	17	PF00069	0.705
MOD_CK1_1	231	237	PF00069	0.507
MOD_CK1_1	277	283	PF00069	0.669
MOD_CK1_1	94	100	PF00069	0.674
MOD_CK2_1	155	161	PF00069	0.643
MOD_CK2_1	38	44	PF00069	0.597
MOD_CK2_1	71	77	PF00069	0.794
MOD_DYRK1A_RPxSP_1	13	17	PF00069	0.760
MOD_GlcNHglycan	100	103	PF01048	0.713
MOD_GlcNHglycan	117	120	PF01048	0.637
MOD_GlcNHglycan	13	16	PF01048	0.598
MOD_GlcNHglycan	132	135	PF01048	0.524
MOD_GlcNHglycan	2	6	PF01048	0.735
MOD_GlcNHglycan	230	233	PF01048	0.501
MOD_GlcNHglycan	296	299	PF01048	0.661
MOD_GlcNHglycan	40	43	PF01048	0.557
MOD_GlcNHglycan	60	64	PF01048	0.475
MOD_GlcNHglycan	73	76	PF01048	0.744
MOD_GlcNHglycan	77	80	PF01048	0.760
MOD_GlcNHglycan	8	11	PF01048	0.675
MOD_GlcNHglycan	96	99	PF01048	0.528
MOD_GSK3_1	117	124	PF00069	0.665
MOD_GSK3_1	125	132	PF00069	0.660
MOD_GSK3_1	210	217	PF00069	0.528
MOD_GSK3_1	224	231	PF00069	0.563
MOD_GSK3_1	71	78	PF00069	0.731
MOD_GSK3_1	94	101	PF00069	0.683
MOD_N-GLC_1	71	76	PF02516	0.733
MOD_NEK2_1	1	6	PF00069	0.610
MOD_NEK2_1	215	220	PF00069	0.501
MOD_PIKK_1	189	195	PF00454	0.574
MOD_PIKK_1	304	310	PF00454	0.754
MOD_PIKK_1	8	14	PF00454	0.731
MOD_PKA_2	242	248	PF00069	0.529
MOD_PKA_2	275	281	PF00069	0.630
MOD_PKA_2	28	34	PF00069	0.631
MOD_PKA_2	54	60	PF00069	0.546
MOD_PKA_2	83	89	PF00069	0.777
MOD_Plk_1	91	97	PF00069	0.751
MOD_Plk_1	98	104	PF00069	0.706
MOD_Plk_4	231	237	PF00069	0.581
MOD_Plk_4	54	60	PF00069	0.555
MOD_ProDKin_1	121	127	PF00069	0.820
MOD_ProDKin_1	13	19	PF00069	0.691
MOD_SUMO_rev_2	171	180	PF00179	0.667
MOD_SUMO_rev_2	218	227	PF00179	0.604
TRG_ENDOCYTIC_2	212	215	PF00928	0.497
TRG_ER_diArg_1	26	29	PF00400	0.694
TRG_ER_diArg_1	267	270	PF00400	0.642

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IK58	Leptomonas seymouri	39%	71%
A0A3Q8IJP5	Leishmania donovani	90%	73%
A4HL02	Leishmania braziliensis	70%	99%
E9AHM4	Leishmania infantum	90%	85%
E9B3E3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	84%	100%