Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania major

UniProt:

Q4Q4Q3_LEIMA

TriTrypDb:

LmjF.32.3690 , LMJLV39_320044800 , LMJSD75_320044900

Length:

973

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q4Q3

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q4Q3

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_MEL_PAP_1	490	496	PF00089	0.651
CLV_NRD_NRD_1	135	137	PF00675	0.820
CLV_NRD_NRD_1	247	249	PF00675	0.768
CLV_NRD_NRD_1	29	31	PF00675	0.832
CLV_NRD_NRD_1	553	555	PF00675	0.835
CLV_NRD_NRD_1	607	609	PF00675	0.816
CLV_NRD_NRD_1	65	67	PF00675	0.804
CLV_NRD_NRD_1	652	654	PF00675	0.537
CLV_NRD_NRD_1	726	728	PF00675	0.855
CLV_NRD_NRD_1	828	830	PF00675	0.813
CLV_NRD_NRD_1	849	851	PF00675	0.823
CLV_NRD_NRD_1	92	94	PF00675	0.695
CLV_NRD_NRD_1	967	969	PF00675	0.638
CLV_PCSK_FUR_1	132	136	PF00082	0.823
CLV_PCSK_FUR_1	63	67	PF00082	0.805
CLV_PCSK_KEX2_1	132	134	PF00082	0.824
CLV_PCSK_KEX2_1	135	137	PF00082	0.771
CLV_PCSK_KEX2_1	240	242	PF00082	0.796
CLV_PCSK_KEX2_1	247	249	PF00082	0.679
CLV_PCSK_KEX2_1	274	276	PF00082	0.644
CLV_PCSK_KEX2_1	63	65	PF00082	0.805
CLV_PCSK_KEX2_1	652	654	PF00082	0.537
CLV_PCSK_KEX2_1	725	727	PF00082	0.843
CLV_PCSK_KEX2_1	739	741	PF00082	0.525
CLV_PCSK_KEX2_1	92	94	PF00082	0.695
CLV_PCSK_KEX2_1	967	969	PF00082	0.568
CLV_PCSK_PC1ET2_1	240	242	PF00082	0.796
CLV_PCSK_PC1ET2_1	274	276	PF00082	0.644
CLV_PCSK_PC1ET2_1	739	741	PF00082	0.840
CLV_PCSK_PC7_1	60	66	PF00082	0.800
CLV_PCSK_PC7_1	735	741	PF00082	0.836
CLV_PCSK_SKI1_1	253	257	PF00082	0.762
CLV_PCSK_SKI1_1	477	481	PF00082	0.650
CLV_PCSK_SKI1_1	701	705	PF00082	0.782
CLV_PCSK_SKI1_1	740	744	PF00082	0.839
CLV_Separin_Metazoa	655	659	PF03568	0.697
DEG_APCC_DBOX_1	671	679	PF00400	0.574
DEG_SPOP_SBC_1	418	422	PF00917	0.825
DEG_SPOP_SBC_1	709	713	PF00917	0.847
DOC_CDC14_PxL_1	928	936	PF14671	0.733
DOC_CYCLIN_RxL_1	938	948	PF00134	0.537
DOC_CYCLIN_yCln2_LP_2	911	917	PF00134	0.570
DOC_CYCLIN_yCln2_LP_2	922	928	PF00134	0.576
DOC_MAPK_gen_1	274	280	PF00069	0.636
DOC_MAPK_gen_1	408	417	PF00069	0.760
DOC_MAPK_gen_1	723	731	PF00069	0.749
DOC_MAPK_gen_1	783	793	PF00069	0.606
DOC_MAPK_MEF2A_6	786	795	PF00069	0.626
DOC_MAPK_MEF2A_6	872	881	PF00069	0.597
DOC_PP1_RVXF_1	491	497	PF00149	0.815
DOC_PP2B_LxvP_1	524	527	PF13499	0.636
DOC_PP2B_LxvP_1	545	548	PF13499	0.815
DOC_PP4_FxxP_1	324	327	PF00568	0.831
DOC_PP4_FxxP_1	881	884	PF00568	0.594
DOC_USP7_MATH_1	127	131	PF00917	0.825
DOC_USP7_MATH_1	140	144	PF00917	0.611
DOC_USP7_MATH_1	17	21	PF00917	0.571
DOC_USP7_MATH_1	175	179	PF00917	0.832
DOC_USP7_MATH_1	287	291	PF00917	0.779
DOC_USP7_MATH_1	304	308	PF00917	0.812
DOC_USP7_MATH_1	310	314	PF00917	0.727
DOC_USP7_MATH_1	341	345	PF00917	0.674
DOC_USP7_MATH_1	353	357	PF00917	0.676
DOC_USP7_MATH_1	36	40	PF00917	0.697
DOC_USP7_MATH_1	390	394	PF00917	0.663
DOC_USP7_MATH_1	419	423	PF00917	0.773
DOC_USP7_MATH_1	483	487	PF00917	0.813
DOC_USP7_MATH_1	492	496	PF00917	0.667
DOC_USP7_MATH_1	527	531	PF00917	0.829
DOC_USP7_MATH_1	681	685	PF00917	0.548
DOC_USP7_MATH_1	696	700	PF00917	0.585
DOC_USP7_MATH_1	709	713	PF00917	0.668
DOC_USP7_MATH_1	771	775	PF00917	0.764
DOC_USP7_MATH_1	779	783	PF00917	0.750
DOC_USP7_MATH_1	831	835	PF00917	0.606
DOC_USP7_MATH_1	884	888	PF00917	0.617
DOC_WW_Pin1_4	204	209	PF00397	0.825
DOC_WW_Pin1_4	283	288	PF00397	0.768
DOC_WW_Pin1_4	3	8	PF00397	0.778
DOC_WW_Pin1_4	32	37	PF00397	0.819
DOC_WW_Pin1_4	323	328	PF00397	0.797
DOC_WW_Pin1_4	339	344	PF00397	0.504
DOC_WW_Pin1_4	364	369	PF00397	0.692
DOC_WW_Pin1_4	388	393	PF00397	0.789
DOC_WW_Pin1_4	427	432	PF00397	0.796
DOC_WW_Pin1_4	436	441	PF00397	0.650
DOC_WW_Pin1_4	442	447	PF00397	0.573
DOC_WW_Pin1_4	457	462	PF00397	0.565
DOC_WW_Pin1_4	499	504	PF00397	0.816
DOC_WW_Pin1_4	710	715	PF00397	0.842
DOC_WW_Pin1_4	742	747	PF00397	0.680
DOC_WW_Pin1_4	796	801	PF00397	0.817
DOC_WW_Pin1_4	813	818	PF00397	0.586
LIG_14-3-3_CanoR_1	203	208	PF00244	0.836
LIG_14-3-3_CanoR_1	223	227	PF00244	0.526
LIG_14-3-3_CanoR_1	247	252	PF00244	0.643
LIG_14-3-3_CanoR_1	30	36	PF00244	0.821
LIG_14-3-3_CanoR_1	400	406	PF00244	0.705
LIG_14-3-3_CanoR_1	484	494	PF00244	0.766
LIG_14-3-3_CanoR_1	518	523	PF00244	0.833
LIG_14-3-3_CanoR_1	53	62	PF00244	0.790
LIG_14-3-3_CanoR_1	562	570	PF00244	0.659
LIG_14-3-3_CanoR_1	599	605	PF00244	0.607
LIG_14-3-3_CanoR_1	608	613	PF00244	0.646
LIG_14-3-3_CanoR_1	644	648	PF00244	0.565
LIG_14-3-3_CanoR_1	710	714	PF00244	0.735
LIG_14-3-3_CanoR_1	725	730	PF00244	0.613
LIG_14-3-3_CanoR_1	740	746	PF00244	0.734
LIG_14-3-3_CanoR_1	759	768	PF00244	0.834
LIG_14-3-3_CanoR_1	786	792	PF00244	0.732
LIG_14-3-3_CanoR_1	812	817	PF00244	0.822
LIG_BIR_II_1	1	5	PF00653	0.778
LIG_BRCT_BRCA1_1	390	394	PF00533	0.660
LIG_deltaCOP1_diTrp_1	80	85	PF00928	0.727
LIG_deltaCOP1_diTrp_1	873	881	PF00928	0.595
LIG_DLG_GKlike_1	247	255	PF00625	0.575
LIG_FHA_1	108	114	PF00498	0.819
LIG_FHA_1	209	215	PF00498	0.629
LIG_FHA_1	230	236	PF00498	0.826
LIG_FHA_1	374	380	PF00498	0.607
LIG_FHA_1	50	56	PF00498	0.789
LIG_FHA_1	519	525	PF00498	0.666
LIG_FHA_1	530	536	PF00498	0.690
LIG_FHA_1	634	640	PF00498	0.786
LIG_FHA_1	643	649	PF00498	0.571
LIG_FHA_1	790	796	PF00498	0.705
LIG_FHA_1	833	839	PF00498	0.691
LIG_FHA_1	889	895	PF00498	0.833
LIG_FHA_1	907	913	PF00498	0.517
LIG_FHA_1	917	923	PF00498	0.635
LIG_FHA_1	935	941	PF00498	0.483
LIG_FHA_2	110	116	PF00498	0.629
LIG_FHA_2	223	229	PF00498	0.802
LIG_FHA_2	241	247	PF00498	0.548
LIG_FHA_2	518	524	PF00498	0.796
LIG_FHA_2	532	538	PF00498	0.605
LIG_FHA_2	665	671	PF00498	0.640
LIG_FHA_2	818	824	PF00498	0.754
LIG_Integrin_RGD_1	104	106	PF01839	0.799
LIG_LIR_Gen_1	82	91	PF02991	0.700
LIG_LIR_Gen_1	823	832	PF02991	0.664
LIG_LIR_LC3C_4	376	379	PF02991	0.606
LIG_LIR_Nem_3	82	88	PF02991	0.706
LIG_LIR_Nem_3	823	828	PF02991	0.669
LIG_LIR_Nem_3	873	879	PF02991	0.591
LIG_MYND_1	503	507	PF01753	0.748
LIG_PDZ_Class_2	968	973	PF00595	0.677
LIG_Pex14_1	81	85	PF04695	0.723
LIG_SH2_CRK	11	15	PF00017	0.743
LIG_SH2_STAT3	553	556	PF00017	0.637
LIG_SH2_STAT5	213	216	PF00017	0.645
LIG_SH2_STAT5	459	462	PF00017	0.617
LIG_SH2_STAT5	970	973	PF00017	0.705
LIG_SH3_2	734	739	PF14604	0.683
LIG_SH3_3	277	283	PF00018	0.818
LIG_SH3_3	443	449	PF00018	0.685
LIG_SH3_3	532	538	PF00018	0.728
LIG_SH3_3	545	551	PF00018	0.620
LIG_SH3_3	622	628	PF00018	0.684
LIG_SH3_3	728	734	PF00018	0.687
LIG_SH3_3	765	771	PF00018	0.630
LIG_SH3_3	880	886	PF00018	0.606
LIG_Sin3_3	375	382	PF02671	0.604
LIG_SUMO_SIM_anti_2	789	796	PF11976	0.597
LIG_SUMO_SIM_par_1	789	796	PF11976	0.630
LIG_SUMO_SIM_par_1	833	840	PF11976	0.612
LIG_TRAF2_1	199	202	PF00917	0.848
LIG_TRAF2_1	243	246	PF00917	0.790
LIG_TRAF2_1	667	670	PF00917	0.636
MOD_CDC14_SPxK_1	342	345	PF00782	0.824
MOD_CDC14_SPxK_1	35	38	PF00782	0.814
MOD_CDK_SPK_2	796	801	PF00069	0.617
MOD_CDK_SPxK_1	32	38	PF00069	0.819
MOD_CDK_SPxK_1	339	345	PF00069	0.831
MOD_CDK_SPxK_1	429	435	PF00069	0.826
MOD_CDK_SPxK_1	457	463	PF00069	0.824
MOD_CDK_SPxxK_3	323	330	PF00069	0.835
MOD_CDK_SPxxK_3	499	506	PF00069	0.818
MOD_CK1_1	123	129	PF00069	0.827
MOD_CK1_1	151	157	PF00069	0.659
MOD_CK1_1	2	8	PF00069	0.783
MOD_CK1_1	20	26	PF00069	0.532
MOD_CK1_1	222	228	PF00069	0.814
MOD_CK1_1	308	314	PF00069	0.826
MOD_CK1_1	344	350	PF00069	0.651
MOD_CK1_1	356	362	PF00069	0.657
MOD_CK1_1	363	369	PF00069	0.726
MOD_CK1_1	395	401	PF00069	0.774
MOD_CK1_1	420	426	PF00069	0.782
MOD_CK1_1	462	468	PF00069	0.817
MOD_CK1_1	54	60	PF00069	0.790
MOD_CK1_1	796	802	PF00069	0.683
MOD_CK1_1	815	821	PF00069	0.613
MOD_CK1_1	888	894	PF00069	0.680
MOD_CK1_1	933	939	PF00069	0.744
MOD_CK2_1	118	124	PF00069	0.825
MOD_CK2_1	181	187	PF00069	0.851
MOD_CK2_1	222	228	PF00069	0.807
MOD_CK2_1	240	246	PF00069	0.545
MOD_CK2_1	517	523	PF00069	0.795
MOD_CK2_1	531	537	PF00069	0.608
MOD_CK2_1	664	670	PF00069	0.639
MOD_CK2_1	817	823	PF00069	0.750
MOD_CK2_1	884	890	PF00069	0.619
MOD_Cter_Amidation	28	31	PF01082	0.834
MOD_DYRK1A_RPxSP_1	710	714	PF00069	0.840
MOD_GlcNHglycan	124	128	PF01048	0.827
MOD_GlcNHglycan	142	145	PF01048	0.529
MOD_GlcNHglycan	150	153	PF01048	0.688
MOD_GlcNHglycan	159	162	PF01048	0.537
MOD_GlcNHglycan	176	180	PF01048	0.566
MOD_GlcNHglycan	183	186	PF01048	0.739
MOD_GlcNHglycan	196	199	PF01048	0.530
MOD_GlcNHglycan	214	217	PF01048	0.557
MOD_GlcNHglycan	232	235	PF01048	0.532
MOD_GlcNHglycan	258	261	PF01048	0.827
MOD_GlcNHglycan	356	359	PF01048	0.771
MOD_GlcNHglycan	394	397	PF01048	0.794
MOD_GlcNHglycan	422	425	PF01048	0.777
MOD_GlcNHglycan	464	467	PF01048	0.815
MOD_GlcNHglycan	485	488	PF01048	0.814
MOD_GlcNHglycan	499	502	PF01048	0.593
MOD_GlcNHglycan	564	567	PF01048	0.838
MOD_GlcNHglycan	589	592	PF01048	0.664
MOD_GlcNHglycan	688	691	PF01048	0.646
MOD_GlcNHglycan	69	73	PF01048	0.813
MOD_GlcNHglycan	705	708	PF01048	0.564
MOD_GlcNHglycan	795	798	PF01048	0.630
MOD_GlcNHglycan	845	848	PF01048	0.711
MOD_GlcNHglycan	887	890	PF01048	0.758
MOD_GlcNHglycan	895	898	PF01048	0.630
MOD_GSK3_1	105	112	PF00069	0.810
MOD_GSK3_1	114	121	PF00069	0.676
MOD_GSK3_1	122	129	PF00069	0.552
MOD_GSK3_1	140	147	PF00069	0.528
MOD_GSK3_1	151	158	PF00069	0.641
MOD_GSK3_1	165	172	PF00069	0.713
MOD_GSK3_1	17	24	PF00069	0.758
MOD_GSK3_1	204	211	PF00069	0.725
MOD_GSK3_1	217	224	PF00069	0.737
MOD_GSK3_1	283	290	PF00069	0.608
MOD_GSK3_1	304	311	PF00069	0.824
MOD_GSK3_1	32	39	PF00069	0.576
MOD_GSK3_1	356	363	PF00069	0.786
MOD_GSK3_1	364	371	PF00069	0.703
MOD_GSK3_1	384	391	PF00069	0.664
MOD_GSK3_1	436	443	PF00069	0.838
MOD_GSK3_1	49	56	PF00069	0.515
MOD_GSK3_1	527	534	PF00069	0.724
MOD_GSK3_1	562	569	PF00069	0.701
MOD_GSK3_1	587	594	PF00069	0.731
MOD_GSK3_1	614	621	PF00069	0.641
MOD_GSK3_1	642	649	PF00069	0.721
MOD_GSK3_1	710	717	PF00069	0.738
MOD_GSK3_1	725	732	PF00069	0.612
MOD_GSK3_1	742	749	PF00069	0.828
MOD_GSK3_1	759	766	PF00069	0.526
MOD_GSK3_1	789	796	PF00069	0.743
MOD_GSK3_1	813	820	PF00069	0.685
MOD_GSK3_1	884	891	PF00069	0.740
MOD_GSK3_1	930	937	PF00069	0.653
MOD_LATS_1	560	566	PF00433	0.832
MOD_N-GLC_1	256	261	PF02516	0.779
MOD_N-GLC_1	31	36	PF02516	0.619
MOD_N-GLC_1	354	359	PF02516	0.826
MOD_N-GLC_1	363	368	PF02516	0.695
MOD_N-GLC_1	642	647	PF02516	0.528
MOD_N-GLC_1	686	691	PF02516	0.773
MOD_N-GLC_1	787	792	PF02516	0.672
MOD_NEK2_1	114	119	PF00069	0.580
MOD_NEK2_1	155	160	PF00069	0.677
MOD_NEK2_1	401	406	PF00069	0.732
MOD_NEK2_1	531	536	PF00069	0.683
MOD_NEK2_1	642	647	PF00069	0.728
MOD_NEK2_1	729	734	PF00069	0.769
MOD_NEK2_1	793	798	PF00069	0.812
MOD_NEK2_1	832	837	PF00069	0.763
MOD_NEK2_1	934	939	PF00069	0.641
MOD_NEK2_1	99	104	PF00069	0.786
MOD_NEK2_2	127	132	PF00069	0.824
MOD_NEK2_2	566	571	PF00069	0.641
MOD_NEK2_2	696	701	PF00069	0.776
MOD_PIKK_1	217	223	PF00454	0.705
MOD_PIKK_1	395	401	PF00454	0.784
MOD_PIKK_1	623	629	PF00454	0.837
MOD_PIKK_1	715	721	PF00454	0.850
MOD_PIKK_1	729	735	PF00454	0.567
MOD_PIKK_1	759	765	PF00454	0.835
MOD_PIKK_1	79	85	PF00454	0.733
MOD_PIKK_1	837	843	PF00454	0.804
MOD_PKA_1	240	246	PF00069	0.792
MOD_PKA_1	247	253	PF00069	0.683
MOD_PKA_1	30	36	PF00069	0.821
MOD_PKA_1	554	560	PF00069	0.829
MOD_PKA_1	608	614	PF00069	0.802
MOD_PKA_1	725	731	PF00069	0.841
MOD_PKA_2	202	208	PF00069	0.836
MOD_PKA_2	222	228	PF00069	0.527
MOD_PKA_2	240	246	PF00069	0.580
MOD_PKA_2	247	253	PF00069	0.583
MOD_PKA_2	344	350	PF00069	0.624
MOD_PKA_2	407	413	PF00069	0.794
MOD_PKA_2	483	489	PF00069	0.813
MOD_PKA_2	492	498	PF00069	0.666
MOD_PKA_2	517	523	PF00069	0.785
MOD_PKA_2	614	620	PF00069	0.796
MOD_PKA_2	643	649	PF00069	0.575
MOD_PKA_2	709	715	PF00069	0.842
MOD_PKA_2	725	731	PF00069	0.590
MOD_PKA_2	771	777	PF00069	0.759
MOD_PKB_1	606	614	PF00069	0.805
MOD_Plk_1	114	120	PF00069	0.823
MOD_Plk_1	123	129	PF00069	0.681
MOD_Plk_1	155	161	PF00069	0.805
MOD_Plk_1	276	282	PF00069	0.672
MOD_Plk_1	642	648	PF00069	0.523
MOD_Plk_1	681	687	PF00069	0.674
MOD_Plk_1	696	702	PF00069	0.570
MOD_Plk_1	787	793	PF00069	0.675
MOD_Plk_1	832	838	PF00069	0.812
MOD_Plk_1	906	912	PF00069	0.608
MOD_Plk_2-3	109	115	PF00069	0.824
MOD_Plk_2-3	44	50	PF00069	0.801
MOD_Plk_4	109	115	PF00069	0.774
MOD_Plk_4	209	215	PF00069	0.629
MOD_Plk_4	287	293	PF00069	0.632
MOD_Plk_4	373	379	PF00069	0.609
MOD_Plk_4	401	407	PF00069	0.701
MOD_Plk_4	44	50	PF00069	0.801
MOD_Plk_4	608	614	PF00069	0.705
MOD_Plk_4	643	649	PF00069	0.717
MOD_Plk_4	789	795	PF00069	0.671
MOD_Plk_4	832	838	PF00069	0.635
MOD_ProDKin_1	204	210	PF00069	0.822
MOD_ProDKin_1	283	289	PF00069	0.769
MOD_ProDKin_1	3	9	PF00069	0.779
MOD_ProDKin_1	32	38	PF00069	0.819
MOD_ProDKin_1	323	329	PF00069	0.798
MOD_ProDKin_1	339	345	PF00069	0.506
MOD_ProDKin_1	364	370	PF00069	0.686
MOD_ProDKin_1	388	394	PF00069	0.791
MOD_ProDKin_1	427	433	PF00069	0.792
MOD_ProDKin_1	436	442	PF00069	0.651
MOD_ProDKin_1	457	463	PF00069	0.824
MOD_ProDKin_1	499	505	PF00069	0.819
MOD_ProDKin_1	710	716	PF00069	0.844
MOD_ProDKin_1	742	748	PF00069	0.678
MOD_ProDKin_1	796	802	PF00069	0.819
MOD_ProDKin_1	813	819	PF00069	0.586
MOD_SUMO_rev_2	495	500	PF00179	0.782
MOD_SUMO_rev_2	659	668	PF00179	0.502
TRG_DiLeu_BaEn_1	109	114	PF01217	0.580
TRG_DiLeu_BaEn_1	833	838	PF01217	0.613
TRG_DiLeu_BaEn_1	94	99	PF01217	0.721
TRG_ENDOCYTIC_2	951	954	PF00928	0.578
TRG_ER_diArg_1	131	134	PF00400	0.824
TRG_ER_diArg_1	605	608	PF00400	0.815
TRG_ER_diArg_1	62	65	PF00400	0.803
TRG_ER_diArg_1	651	653	PF00400	0.554
TRG_ER_diArg_1	672	675	PF00400	0.719
TRG_ER_diArg_1	725	727	PF00400	0.803
TRG_ER_diArg_1	91	93	PF00400	0.695
TRG_Pf-PMV_PEXEL_1	298	302	PF00026	0.592

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A3Q8IH67	Leishmania donovani	84%	100%
A4I8I7	Leishmania infantum	84%	100%
E9B3E7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	78%	100%