Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania major

UniProt:

Q4Q4N7_LEIMA

TriTrypDb:

LmjF.32.3850 , LMJLV39_320046400 , LMJSD75_320046600

Length:

291

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

Q4Q4N7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: Q4Q4N7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	225	229	PF00656	0.496
CLV_NRD_NRD_1	120	122	PF00675	0.441
CLV_NRD_NRD_1	232	234	PF00675	0.493
CLV_NRD_NRD_1	34	36	PF00675	0.549
CLV_NRD_NRD_1	82	84	PF00675	0.547
CLV_PCSK_FUR_1	80	84	PF00082	0.508
CLV_PCSK_KEX2_1	232	234	PF00082	0.493
CLV_PCSK_KEX2_1	283	285	PF00082	0.749
CLV_PCSK_KEX2_1	34	36	PF00082	0.549
CLV_PCSK_KEX2_1	82	84	PF00082	0.551
CLV_PCSK_PC1ET2_1	283	285	PF00082	0.630
CLV_PCSK_SKI1_1	121	125	PF00082	0.488
CLV_PCSK_SKI1_1	185	189	PF00082	0.411
CLV_PCSK_SKI1_1	83	87	PF00082	0.592
DEG_APCC_DBOX_1	150	158	PF00400	0.574
DEG_Nend_UBRbox_1	1	4	PF02207	0.606
DEG_SPOP_SBC_1	265	269	PF00917	0.583
DOC_MAPK_MEF2A_6	158	167	PF00069	0.545
DOC_PP1_RVXF_1	107	113	PF00149	0.408
DOC_USP7_MATH_1	231	235	PF00917	0.469
DOC_USP7_MATH_1	4	8	PF00917	0.577
DOC_USP7_MATH_1	43	47	PF00917	0.578
DOC_USP7_MATH_1	9	13	PF00917	0.539
DOC_WW_Pin1_4	135	140	PF00397	0.529
DOC_WW_Pin1_4	266	271	PF00397	0.604
LIG_Actin_WH2_2	106	123	PF00022	0.358
LIG_Actin_WH2_2	71	89	PF00022	0.443
LIG_FHA_1	190	196	PF00498	0.435
LIG_FHA_2	23	29	PF00498	0.484
LIG_LIR_Gen_1	249	255	PF02991	0.550
LIG_LIR_Nem_3	249	253	PF02991	0.561
LIG_MYND_3	174	178	PF01753	0.443
LIG_SH2_STAT5	114	117	PF00017	0.319
LIG_SH2_STAT5	208	211	PF00017	0.421
LIG_SH3_1	158	164	PF00018	0.549
LIG_SH3_3	133	139	PF00018	0.560
LIG_SH3_3	158	164	PF00018	0.534
LIG_SUMO_SIM_par_1	22	28	PF11976	0.463
LIG_TRAF2_1	129	132	PF00917	0.482
LIG_TRAF2_1	169	172	PF00917	0.538
LIG_WRC_WIRS_1	247	252	PF05994	0.507
MOD_CK1_1	249	255	PF00069	0.547
MOD_CK1_1	257	263	PF00069	0.722
MOD_CK1_1	266	272	PF00069	0.525
MOD_CK1_1	53	59	PF00069	0.471
MOD_CK2_1	126	132	PF00069	0.565
MOD_CK2_1	53	59	PF00069	0.486
MOD_GlcNHglycan	11	14	PF01048	0.558
MOD_GlcNHglycan	128	131	PF01048	0.619
MOD_GlcNHglycan	257	260	PF01048	0.665
MOD_GlcNHglycan	6	9	PF01048	0.604
MOD_GlcNHglycan	87	90	PF01048	0.443
MOD_GSK3_1	260	267	PF00069	0.609
MOD_GSK3_1	43	50	PF00069	0.754
MOD_NEK2_1	126	131	PF00069	0.492
MOD_NEK2_1	85	90	PF00069	0.461
MOD_NEK2_1	95	100	PF00069	0.508
MOD_PIKK_1	189	195	PF00454	0.482
MOD_PIKK_1	257	263	PF00454	0.608
MOD_PIKK_1	43	49	PF00454	0.583
MOD_PIKK_1	95	101	PF00454	0.529
MOD_PKA_2	150	156	PF00069	0.577
MOD_PKA_2	231	237	PF00069	0.544
MOD_Plk_4	246	252	PF00069	0.539
MOD_ProDKin_1	135	141	PF00069	0.529
MOD_ProDKin_1	266	272	PF00069	0.600
TRG_DiLeu_BaEn_4	172	178	PF01217	0.392
TRG_ER_diArg_1	102	105	PF00400	0.474
TRG_NES_CRM1_1	242	255	PF08389	0.562
TRG_Pf-PMV_PEXEL_1	121	125	PF00026	0.368
TRG_Pf-PMV_PEXEL_1	158	162	PF00026	0.583

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I265	Leptomonas seymouri	32%	84%
A0A3Q8IEK8	Leishmania donovani	86%	100%
A4HL22	Leishmania braziliensis	59%	100%
A4I8K3	Leishmania infantum	86%	100%
E9B3G3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	100%